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aminoglutethimide and Lymph Node Metastasis

aminoglutethimide has been researched along with Lymph Node Metastasis in 16 studies

Aminoglutethimide: An aromatase inhibitor that is used in the treatment of advanced BREAST CANCER.
aminoglutethimide : A dicarboximide that is a six-membered cyclic compound having ethyl and 4-aminophenyl substituents at the 3-position.

Research Excerpts

ExcerptRelevanceReference
"3 months, women who received anastrozole (n = 387) had a statistically significantly reduced risk of recurrence (locoregional recurrence, contralateral breast cancer, or distant metastasis) compared with women who received no further treatment (n = 469; hazard ratio = 0."9.12Extended adjuvant therapy with anastrozole among postmenopausal breast cancer patients: results from the randomized Austrian Breast and Colorectal Cancer Study Group Trial 6a. ( Dadak, C; Gnant, M; Greil, R; Hofbauer, F; Jakesz, R; Kubista, E; Kwasny, W; Mlineritsch, B; Renner, K; Rücklinger, E; Samonigg, H; Schmid, M; Stierer, M; Tausch, C, 2007)
"The study purpose was to evaluate aminoglutethimide (AG) as adjuvant therapy in patients with primary node-positive breast cancer in a randomized double-blind placebo-controlled trial."9.07Adjuvant aminoglutethimide for postmenopausal patients with primary breast cancer: analysis at 8 years. ( Coombes, RC; Easton, D; Ford, HT; Jones, AL; Law, M; McKinna, JA; Nash, A; Powles, TJ; Smith, IE; Tidy, A, 1992)
"Three hundred and twenty-two postmenopausal patients with primary breast cancer and ipsilateral axillary node involvement were randomized to receive aminoglutethimide and hydrocortisone or placebo for 2 years in a double blind randomized trial between April 1980 and March 1985."9.06Adjuvant aminoglutethimide therapy for postmenopausal patients with primary breast cancer. ( Bradbeer, J; Chilvers, C; Coombes, RC; Easton, D; Ford, HT; McKinna, A; Powles, TJ; Smith, IE; White, H; Yarnold, J, 1987)
"3 months, women who received anastrozole (n = 387) had a statistically significantly reduced risk of recurrence (locoregional recurrence, contralateral breast cancer, or distant metastasis) compared with women who received no further treatment (n = 469; hazard ratio = 0."5.12Extended adjuvant therapy with anastrozole among postmenopausal breast cancer patients: results from the randomized Austrian Breast and Colorectal Cancer Study Group Trial 6a. ( Dadak, C; Gnant, M; Greil, R; Hofbauer, F; Jakesz, R; Kubista, E; Kwasny, W; Mlineritsch, B; Renner, K; Rücklinger, E; Samonigg, H; Schmid, M; Stierer, M; Tausch, C, 2007)
"In order to evaluate the effectiveness of second and third line hormone therapy for postmenopausal (spontaneous or surgical) women with metastatic tamoxifen-resistant breast cancer, 293 women aged 36 to 91 (mean 63."5.07[2d and 3d line hormonal therapy in postmenopausal metastatic breast tumor. Comparison of medroxyprogesterone acetate and aminoglutethimide in tamoxifen-resistant patients]. ( Ayme, Y; Carton, M; Daban, A; Delozier, T; Fargeot, P; Ferri, L; Fumoleau, P; Garcia-Giralt, E; Gorins, A; Omodei Zorini, C, 1994)
"The study purpose was to evaluate aminoglutethimide (AG) as adjuvant therapy in patients with primary node-positive breast cancer in a randomized double-blind placebo-controlled trial."5.07Adjuvant aminoglutethimide for postmenopausal patients with primary breast cancer: analysis at 8 years. ( Coombes, RC; Easton, D; Ford, HT; Jones, AL; Law, M; McKinna, JA; Nash, A; Powles, TJ; Smith, IE; Tidy, A, 1992)
"Three hundred and twenty-two postmenopausal patients with primary breast cancer and ipsilateral axillary node involvement were randomized to receive aminoglutethimide and hydrocortisone or placebo for 2 years in a double blind randomized trial between April 1980 and March 1985."5.06Adjuvant aminoglutethimide therapy for postmenopausal patients with primary breast cancer. ( Bradbeer, J; Chilvers, C; Coombes, RC; Easton, D; Ford, HT; McKinna, A; Powles, TJ; Smith, IE; White, H; Yarnold, J, 1987)
"Of 221 patients with breast cancer of known epidermal growth factor receptor (EGFR) and oestrogen receptor (ER) status, 99 had developed recurrences during the period of follow-up (range 3-60 months, median 24 months)."1.28Relationship between c-erbB-2 protein product expression and response to endocrine therapy in advanced breast cancer. ( Angus, B; Cairns, J; Farndon, J; Harris, AL; Horne, CH; Nicholson, S; Sainsbury, JR; Wright, C, 1992)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19906 (37.50)18.7374
1990's8 (50.00)18.2507
2000's2 (12.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hobdy, EM1
Shafi, NQ1
Kummar, S1
Jakesz, R1
Greil, R1
Gnant, M1
Schmid, M1
Kwasny, W1
Kubista, E1
Mlineritsch, B1
Tausch, C1
Stierer, M1
Hofbauer, F1
Renner, K1
Dadak, C1
Rücklinger, E1
Samonigg, H1
Beccati, MD1
Degli Azzi Vitelleschi, I1
Marangolo, M1
Semiglazov, VF1
Ivanov, VG1
Moiseenko, VM1
Bershteĭn, LM1
Ivanova, OA1
Tsyrlina, EV1
Barash, NIu1
Bozhok, AA1
Garcia-Giralt, E1
Omodei Zorini, C1
Ferri, L1
Ayme, Y1
Carton, M1
Daban, A1
Delozier, T1
Fargeot, P1
Fumoleau, P1
Gorins, A1
Bonneterre, J1
Adenis, A1
Pion, JM1
Cambier, L1
Kamus, E1
Hecquet, B1
Cameron, DA1
Anderson, ED2
Levack, P1
Hawkins, RA2
Anderson, TJ2
Leonard, RC2
Forrest, AP2
Chetty, U2
Scott, RD1
Wright, C1
Nicholson, S2
Angus, B1
Sainsbury, JR1
Farndon, J1
Cairns, J1
Harris, AL1
Horne, CH1
Jones, AL1
Powles, TJ3
Law, M1
Tidy, A1
Easton, D3
Coombes, RC3
Smith, IE3
McKinna, JA1
Nash, A1
Ford, HT2
Henry, JA1
Piggott, NH1
Mallick, UK1
Farndon, JR1
Westley, BR1
May, FE1
Jonat, W1
Maass, H1
Lönning, PE1
Wiedemann, G1
Kvinnsland, S1
Lundgren, S1
Chilvers, C2
Thomas, L1
Adcock, H1
Gazet, JC1
Nash, AG1
Bradbeer, J2
McKinna, A1
White, H1
Yarnold, J1

Trials

7 trials available for aminoglutethimide and Lymph Node Metastasis

ArticleYear
Extended adjuvant therapy with anastrozole among postmenopausal breast cancer patients: results from the randomized Austrian Breast and Colorectal Cancer Study Group Trial 6a.
    Journal of the National Cancer Institute, 2007, Dec-19, Volume: 99, Issue:24

    Topics: Aged; Aged, 80 and over; Aminoglutethimide; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase

2007
[2d and 3d line hormonal therapy in postmenopausal metastatic breast tumor. Comparison of medroxyprogesterone acetate and aminoglutethimide in tamoxifen-resistant patients].
    La Clinica terapeutica, 1994, Volume: 145, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Aminoglutethimide; Breast Neoplasms; Drug Resistance; Female; Humans

1994
Primary systemic therapy for operable breast cancer--10-year survival data after chemotherapy and hormone therapy.
    British journal of cancer, 1997, Volume: 76, Issue:8

    Topics: Adult; Aged; Aminoglutethimide; Androstenedione; Antineoplastic Combined Chemotherapy Protocols; Axi

1997
Adjuvant aminoglutethimide for postmenopausal patients with primary breast cancer: analysis at 8 years.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1992, Volume: 10, Issue:10

    Topics: Aged; Aminoglutethimide; Breast Neoplasms; Chemotherapy, Adjuvant; Double-Blind Method; Female; Huma

1992
Primary systemic therapy for operable breast cancer.
    British journal of cancer, 1991, Volume: 63, Issue:4

    Topics: Adult; Aged; Aminoglutethimide; Androstenedione; Antineoplastic Combined Chemotherapy Protocols; Aro

1991
A double blind randomised clinical trial of adjuvant aminoglutethimide versus placebo given to post menopausal patients with histologically confirmed stage II breast cancer.
    Breast cancer research and treatment, 1986, Volume: 7 Suppl

    Topics: Aged; Aminoglutethimide; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Doub

1986
Adjuvant aminoglutethimide therapy for postmenopausal patients with primary breast cancer.
    Cancer research, 1987, May-01, Volume: 47, Issue:9

    Topics: Aged; Aminoglutethimide; Breast Neoplasms; Clinical Trials as Topic; Double-Blind Method; Female; Hu

1987

Other Studies

9 other studies available for aminoglutethimide and Lymph Node Metastasis

ArticleYear
Prostate cancer metastasis to supraclavicular lymph node.
    Clinical advances in hematology & oncology : H&O, 2004, Volume: 2, Issue:4

    Topics: Acid Phosphatase; Adenocarcinoma; Aged; Aminoglutethimide; Antineoplastic Combined Chemotherapy Prot

2004
[Pharmacological suppression of the adrenal gland. Considerations on a clinical case].
    La Clinica terapeutica, 1982, Jul-31, Volume: 102, Issue:2

    Topics: Adenocarcinoma, Mucinous; Adrenocortical Hyperfunction; Adult; Aminoglutethimide; Antineoplastic Age

1982
[The adjuvant hormonal therapy of breast cancer].
    Voprosy onkologii, 1995, Volume: 41, Issue:2

    Topics: Aminoglutethimide; Antineoplastic Agents, Hormonal; Breast Neoplasms; Chemotherapy, Adjuvant; Diethy

1995
Aminoglutethimide (AG) and hydrocortisone (HC) in bone metastases: a retrospective study.
    The Journal of steroid biochemistry and molecular biology, 1993, Volume: 44, Issue:4-6

    Topics: Adult; Aged; Aminoglutethimide; Bone Neoplasms; Breast Neoplasms; Female; Follow-Up Studies; Humans;

1993
Treatment of an adrenal cortical carcinoma with a combination of o,p'-DDD and aminoglutethimide.
    Postgraduate medical journal, 1975, Volume: 51, Issue:591

    Topics: 11-Hydroxycorticosteroids; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenalectomy; Adult;

1975
Relationship between c-erbB-2 protein product expression and response to endocrine therapy in advanced breast cancer.
    British journal of cancer, 1992, Volume: 65, Issue:1

    Topics: Adult; Aged; Aminoglutethimide; Biomarkers, Tumor; Breast Neoplasms; ErbB Receptors; Female; Follow-

1992
pNR-2/pS2 immunohistochemical staining in breast cancer: correlation with prognostic factors and endocrine response.
    British journal of cancer, 1991, Volume: 63, Issue:4

    Topics: Aminoglutethimide; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Female; Humans; Immuno

1991
[Endocrine therapy of breast cancer].
    Zentralblatt fur Gynakologie, 1987, Volume: 109, Issue:10

    Topics: Aminoglutethimide; Antibodies, Monoclonal; Breast Neoplasms; Combined Modality Therapy; Female; Horm

1987
[Which hormone therapy should be used in advanced breast carcinoma in males?].
    Deutsche medizinische Wochenschrift (1946), 1988, Sep-02, Volume: 113, Issue:35

    Topics: Adenocarcinoma; Aged; Aminoglutethimide; Axilla; Breast Neoplasms; Dexamethasone; Drug Evaluation; H

1988