aminoglutethimide has been researched along with Hypercholesterolemia in 4 studies
Aminoglutethimide: An aromatase inhibitor that is used in the treatment of advanced BREAST CANCER.
aminoglutethimide : A dicarboximide that is a six-membered cyclic compound having ethyl and 4-aminophenyl substituents at the 3-position.
Hypercholesterolemia: A condition with abnormally high levels of CHOLESTEROL in the blood. It is defined as a cholesterol value exceeding the 95th percentile for the population.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Plasma levels of cholesterol, HDL cholesterol (HDL chol), LDL cholesterol (LDL chol), triglycerides, Al apoprotein and B apoprotein were studied in 73 patients receiving 500 mg aminoglutethimide (AG)/day and 40 mg hydrocortisone/day for advanced breast cancer." | 3.67 | [Aminoglutethimide-induced dyslipemia. Clinical study]. ( Bonneterre, J; Demaille, A; Fournier, C; Hecquet, B; Nguyen, M, 1985) |
| "Treatment with aminoglutethimide alone on day 7 post hCG did not further depress the already low HMG-CoA reductase activity, but ACAT and cholesterol ester storage were stimulated while sterol esterase activity was not altered." | 1.26 | Regulation of ovarian cholesterol metabolism: control of 3-hydroxy-3-methylglutaryl coenzyme A reductase and acyl coenzyme A:cholesterol acyltransferase. ( Schuler, LA; Strauss, JF; Toaff, ME, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bonneterre, J | 2 |
| Nguyen, M | 2 |
| Hecquet, B | 2 |
| Cappelaere, P | 1 |
| Schuler, LA | 1 |
| Toaff, ME | 1 |
| Strauss, JF | 1 |
| DiBartolomeis, MJ | 1 |
| Moore, RW | 1 |
| Peterson, RE | 1 |
| Jefcoate, CR | 1 |
| Fournier, C | 1 |
| Demaille, A | 1 |
4 other studies available for aminoglutethimide and Hypercholesterolemia
| Article | Year |
|---|---|
Aminoglutethimide-induced hypercholesterolaemia.
Topics: Aminoglutethimide; Breast Neoplasms; Female; Humans; Hypercholesterolemia; Time Factors | 1984 |
Regulation of ovarian cholesterol metabolism: control of 3-hydroxy-3-methylglutaryl coenzyme A reductase and acyl coenzyme A:cholesterol acyltransferase.
Topics: Acyltransferases; Adenine; Aminoglutethimide; Animals; Cholesterol; Chorionic Gonadotropin; Female; | 1981 |
Hypercholesterolemia and the regulation of adrenal steroidogenesis in 2,3,7,8-tetrachlorodibenzo-p-dioxin-treated rats.
Topics: Adrenal Glands; Aminoglutethimide; Animals; Cholesterol; Cholesterol Side-Chain Cleavage Enzyme; Cor | 1986 |
[Aminoglutethimide-induced dyslipemia. Clinical study].
Topics: Aminoglutethimide; Apolipoprotein A-I; Apolipoproteins A; Apolipoproteins B; Breast Neoplasms; Chole | 1985 |