Page last updated: 2024-10-22

aminoglutethimide and Hormone-Dependent Neoplasms

aminoglutethimide has been researched along with Hormone-Dependent Neoplasms in 52 studies

Aminoglutethimide: An aromatase inhibitor that is used in the treatment of advanced BREAST CANCER.
aminoglutethimide : A dicarboximide that is a six-membered cyclic compound having ethyl and 4-aminophenyl substituents at the 3-position.

Research Excerpts

ExcerptRelevanceReference
"Aminoglutethimide is an effective treatment for advanced postmenopausal breast cancer, acting in a novel way."8.77Aminoglutethimide--a new endocrine therapy in breast cancer. A cancer research review. ( Harris, AL, 1985)
"44 postmenopausal women with progressive soft tissue, osseous and/or pleuropulmonal metastases of breast cancer were treated with aminoglutethimide (Rodazol) and hydrocortisone."7.68[Results of hormone therapy with aminoglutethimide (Rodazol) in postmenopausal metastatic breast cancer]. ( Brockmann, B; Geschke, E; Schmidt, UM, 1991)
"About one third of unselected postmenopausal women with advanced breast cancer respond to treatment with aminoglutethimide and hydrocortisone, but they all eventually relapse, and further progression of disease occurs."7.67Endocrine changes associated with relapse in advanced breast cancer patients on aminoglutethimide therapy. ( Dowsett, M; Harris, AL; Jeffcoate, SL; Smith, IE, 1984)
"Thirty-four postmenopausal patients with advanced breast cancer had an overall objective response rate of 47% when treated with aminoglutethimide and hydrocortisone initially and a response rate of 24% when crossed over to therapy with tamoxifen after progression on aminoglutethimide."7.66Cross-over comparison of tamoxifen and aminoglutethimide in advanced breast cancer. ( Boucher, AE; Dixon, RJ; Harvey, HA; Lipton, A; Santen, RJ; Shafik, AS; White, DS, 1982)
"Aminoglutethimide (AG) is an effective chemical ablative form of therapy for metastatic breast cancer in postmenopausal women."7.66Influence of estrogen receptor status on response of metastatic breast cancer to aminoglutethimide therapy. ( Cox, CE; Harvey, HA; Lawrence, BV; Lipton, A; Santen, RJ; Smart, EK; Wells, SA; White, DS, 1980)
"Human breast neoplasms can be divided into hormone-dependent and hormone-independent subtypes."5.26Adequacy of estrogen suppression with aminoglutethimide and hydrocortisone as treatment of human breast cancer: correlation of hormonal data with clinical responses. ( Boucher, AE; Harvey, H; Lipton, A; Samojlik, E; Santen, RJ; Worgul, TJ, 1982)
"Randomized clinical trials have established the role of third-generation aromatase inhibitors (AIs) (letrozole, anastrozole, and exemestane) as standard treatment for patients with hormone-sensitive metastatic breast cancer who have experienced disease progression with antiestrogen therapy."4.82A comparison of the efficacy of aromatase inhibitors in second-line treatment of metastatic breast cancer. ( Rose, C, 2003)
"The new generation of selective aromatase inhibitors (anastrozole, letrozole and exemestane) offer a significant efficacy and safety advantage over both older agents in this class (aminoglutethimide) and the progestins (megestrol acetate (MA)), as second-line treatment for postmenopausal women with advanced hormone-dependent breast cancer who have failed on tamoxifen therapy."4.81A summary of second-line randomized studies of aromatase inhibitors. ( Buzdar, AU, 2001)
" Among the steroid substrate analogs, 4-hydroxyandrostenedione has been shown to be effective in breast cancer patients with advanced disease and was recently approved for treatment in the United Kingdom."4.78Aromatase, its inhibitors and their use in breast cancer treatment. ( Brodie, AM, 1993)
"Aminoglutethimide is an effective treatment for advanced postmenopausal breast cancer, acting in a novel way."4.77Aminoglutethimide--a new endocrine therapy in breast cancer. A cancer research review. ( Harris, AL, 1985)
"We evaluated the comparative effects of aminoglutethimide (AG) on androgen and estrogen levels estrone ([E1], estradiol [E2], plasma dehydroepiandrosterone-sulfate [DHEA-S], testosterone [T], dihydrotestosterone [DHT], delta 4-androstenedione [delta 4-A]), follicle-stimulating hormone (FSH), luteinizing hormone (LH), and prolactin in postmenopausal patients with breast cancer randomly allocated to either AG treatment or bilateral surgical adrenalectomy as a control group."4.76Preservation of androgen secretion during estrogen suppression with aminoglutethimide in the treatment of metastatic breast carcinoma. ( Samojlik, E; Santen, RJ; Veldhuis, JD; Wells, SA, 1980)
"Eleven postmenopausal patients with advanced breast cancer were assessed for their response and endocrine changes to low-dose aminoglutethimide (250 mg twice a day) therapy without steroid administration."3.68Low-dose aminoglutethimide therapy without glucocorticoid administration. Clinical and hormonal findings. ( Kahán, Z; Tóth, I; Vecsernyés, M, 1992)
"44 postmenopausal women with progressive soft tissue, osseous and/or pleuropulmonal metastases of breast cancer were treated with aminoglutethimide (Rodazol) and hydrocortisone."3.68[Results of hormone therapy with aminoglutethimide (Rodazol) in postmenopausal metastatic breast cancer]. ( Brockmann, B; Geschke, E; Schmidt, UM, 1991)
"About one third of unselected postmenopausal women with advanced breast cancer respond to treatment with aminoglutethimide and hydrocortisone, but they all eventually relapse, and further progression of disease occurs."3.67Endocrine changes associated with relapse in advanced breast cancer patients on aminoglutethimide therapy. ( Dowsett, M; Harris, AL; Jeffcoate, SL; Smith, IE, 1984)
"Thirty-four postmenopausal patients with advanced breast cancer had an overall objective response rate of 47% when treated with aminoglutethimide and hydrocortisone initially and a response rate of 24% when crossed over to therapy with tamoxifen after progression on aminoglutethimide."3.66Cross-over comparison of tamoxifen and aminoglutethimide in advanced breast cancer. ( Boucher, AE; Dixon, RJ; Harvey, HA; Lipton, A; Santen, RJ; Shafik, AS; White, DS, 1982)
"Aminoglutethimide (AG) is an effective chemical ablative form of therapy for metastatic breast cancer in postmenopausal women."3.66Influence of estrogen receptor status on response of metastatic breast cancer to aminoglutethimide therapy. ( Cox, CE; Harvey, HA; Lawrence, BV; Lipton, A; Santen, RJ; Smart, EK; Wells, SA; White, DS, 1980)
"In conclusion, in a group of metastatic breast cancer patients, treated routinely by systemic therapies it was found, that the use of higher cut-off point for EGF-R positivity can improve the prediction of endocrine sensitivity."2.69Content of epidermal growth factor receptor in metastatic breast cancer: its role in endocrine sensitivity prediction. ( Branković-Magić, MV; Mitrovic, LB; Nesković-Konstantinović, ZB; Nikolić-Vukosavljević, DB; Spuzić, I, 2000)
" Patients were then treated with aminoglutethimide according to one of two dosage regimens: (a) aminoglutethimide 1000 mg/day + hydrocortisone 20 mg/day, and (b) aminoglutethimide 250 mg/day."2.66Correlation of breast tumour aromatase activity and response to aromatase inhibition with aminoglutethimide. ( Bezwoda, WR; Dansey, R; Mansoor, N, 1987)
"Thus, management of metastatic breast cancer has largely shifted from surgeons to medical oncologists."2.40Use of aromatase inhibitors in postmenopausal women with advanced breast cancer. ( Buzdar, AU; Roseman, BJ; Singletary, SE, 1997)
"Aminoglutethimide is an inhibitor of adrenal steroid biosynthesis and blocks the conversion of cholesterol to pregnenolone, and therefore reduces levels of adrenal androgens, which are a source of estrogens in both premenopausal and postmenopausal women."2.40[Aromatase inhibitors--new possibilities in treatment of breast carcinoma]. ( Friedrichs, K; Jänicke, F, 1998)
"Aminoglutethimide was the first widely used aromatase inhibitor but had several clinical drawbacks."2.40Use of aromatase inhibitors in breast carcinoma. ( Harvey, HA; Santen, RJ, 1999)
"Research using cell-lines of human breast cancer also suggests that anti-progestins and agents capable of antagonizing steroid-induced growth factors will inhibit tumour growth."2.37Fundamental research leading to improved endocrine therapy for breast cancer. ( Miller, WR, 1987)
"One-third of the cases of breast cancer in postmenopausal women are hormone-dependent and the lesions regress upon treatment with antiestrogens or inhibition of estrogen biosynthesis."2.37Enzymatic control of estrogen production in human breast cancer: relative significance of aromatase versus sulfatase pathways. ( Feil, PD; Leszczynski, D; Manni, A; Santen, RJ; Santner, SJ; Tilson-Mallet, N; Wright, C, 1986)
" These findings led to development of a practical regimen of escalating aminoglutethimide dosage in combination with hydrocortisone for treatment of patients with breast carcinoma."1.26In vivo and in vitro pharmacological studies of aminoglutethimide as an aromatase inhibitor. ( Rosen, HR; Samojlik, E; Santen, RJ; Santner, SJ; Tilsen-Mallett, N; Veldhuis, JD, 1982)
"Human breast neoplasms can be divided into hormone-dependent and hormone-independent subtypes."1.26Adequacy of estrogen suppression with aminoglutethimide and hydrocortisone as treatment of human breast cancer: correlation of hormonal data with clinical responses. ( Boucher, AE; Harvey, H; Lipton, A; Samojlik, E; Santen, RJ; Worgul, TJ, 1982)

Research

Studies (52)

TimeframeStudies, this research(%)All Research%
pre-199026 (50.00)18.7374
1990's19 (36.54)18.2507
2000's7 (13.46)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hill, J1
Moore, H1
Vogel, CL1
Rose, C1
Vicent, MJ1
Greco, F1
Nicholson, RI2
Paul, A1
Griffiths, PC1
Duncan, R1
Mauri, D1
Pavlidis, N1
Polyzos, NP1
Ioannidis, JP1
Bruning, PF1
Bonfrer, JM1
De Jong-Bakker, M1
Nooyen, W1
Kvinnsland, S1
Lønning, PE1
Dahl, O1
Harvey, HA5
Lipton, A4
White, DS2
Santen, RJ9
Boucher, AE2
Shafik, AS1
Dixon, RJ1
Dowsett, M3
Harris, AL3
Smith, IE2
Jeffcoate, SL1
Samojlik, E3
Veldhuis, JD2
Wells, SA2
Santner, SJ2
Tilsen-Mallett, N1
Rosen, HR1
Worgul, TJ1
Harvey, H1
Sterns, EE1
Bird, CE1
Mackie, KW1
Lawrence, BV1
Cox, CE1
Smart, EK1
Brodie, AM2
Pronzato, P1
Rubagotti, A1
Amoroso, D1
Bertelli, G1
Queirolo, P1
Sertoli, MR1
Rosso, M1
Gallotti, P1
Monzeglio, C1
Rosso, R1
Stein, M1
Hultborn, R1
Johansson-Terje, I1
Bergh, J1
Glas, U1
Hallsten, L1
Hatschek, T1
Holmberg, E1
Ideström, K1
Norberg, B1
Ranstam, J1
Söderberg, M1
Wallgren, UB1
Roseman, BJ1
Buzdar, AU2
Singletary, SE1
Cameron, DA1
Anderson, ED1
Levack, P1
Hawkins, RA1
Anderson, TJ1
Leonard, RC1
Forrest, AP1
Chetty, U1
Bare, RL1
Torti, FM1
Friedrichs, K1
Jänicke, F1
Ragaz, J1
Nesković-Konstantinović, ZB1
Nikolić-Vukosavljević, DB1
Branković-Magić, MV1
Mitrovic, LB1
Spuzić, I1
Kardinal, CG1
Donegan, WL1
Kahán, Z1
Tóth, I1
Vecsernyés, M1
Schmidt, UM1
Brockmann, B1
Geschke, E1
Clavel, M1
Fukuoka, M1
Kitawaki, J1
Yamamoto, T1
Okada, H1
Garcia Giralt, E1
Omodei Zorini, C1
von Matthiessen, H1
Distler, W1
Miller, WR2
Fukutomi, T1
Knönagel, H1
Hauri, D1
Wander, HE1
Teichmann, AT1
Cremer, P1
Wieland, H1
Kruse, B1
Nagel, GA1
Kuhn, W1
Seidel, D1
Paridaens, RJ1
Arrigo, C1
Heuson, JC1
Leszczynski, D1
Tilson-Mallet, N1
Feil, PD1
Wright, C1
Manni, A1
Walker, KJ1
Davies, P1
Gorgone, S1
Lorenzini, C1
Palmeri, R1
Belnome, N1
Calbo, L1
Dattola, P1
Melita, P1
Bezwoda, WR1
Mansoor, N1
Dansey, R1
Wing, LY1
Goss, P1
Coombes, RC1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Stereotactic Body Radiotherapy (SBRT) for the Treatment of OligoMetastasis in Breast Cancer Patients (STOMP): A Prospective Feasibility Trial[NCT03295916]Early Phase 130 participants (Anticipated)Interventional2018-01-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

24 reviews available for aminoglutethimide and Hormone-Dependent Neoplasms

ArticleYear
Aromatase inhibitors in breast cancer: current and evolving roles.
    Cleveland Clinic journal of medicine, 2002, Volume: 69, Issue:7

    Topics: Aminoglutethimide; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Breast Neoplasm

2002
Update on the current use of hormonals as therapy in advanced breast cancer.
    Anti-cancer drugs, 2003, Volume: 14, Issue:4

    Topics: Aminoglutethimide; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical

2003
A comparison of the efficacy of aromatase inhibitors in second-line treatment of metastatic breast cancer.
    American journal of clinical oncology, 2003, Volume: 26, Issue:4

    Topics: Aminoglutethimide; Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast

2003
Survival with aromatase inhibitors and inactivators versus standard hormonal therapy in advanced breast cancer: meta-analysis.
    Journal of the National Cancer Institute, 2006, Sep-20, Volume: 98, Issue:18

    Topics: Adult; Aged; Aminoglutethimide; Anastrozole; Androstenedione; Antineoplastic Agents, Hormonal; Aroma

2006
Preservation of androgen secretion during estrogen suppression with aminoglutethimide in the treatment of metastatic breast carcinoma.
    The Journal of clinical investigation, 1980, Volume: 65, Issue:3

    Topics: Adrenalectomy; Aged; Aminoglutethimide; Androgens; Breast Neoplasms; Castration; Estrogens; Female;

1980
Aromatase, its inhibitors and their use in breast cancer treatment.
    Pharmacology & therapeutics, 1993, Volume: 60, Issue:3

    Topics: Aminoglutethimide; Androstenedione; Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Breast N

1993
Use of aromatase inhibitors in postmenopausal women with advanced breast cancer.
    Journal of surgical oncology, 1997, Volume: 66, Issue:3

    Topics: Aminoglutethimide; Anastrozole; Androstenedione; Antineoplastic Agents; Antineoplastic Agents, Hormo

1997
Emerging role of aromatase inhibitors in the treatment of breast cancer.
    Oncology (Williston Park, N.Y.), 1998, Volume: 12, Issue:3 Suppl 5

    Topics: Aged; Aminoglutethimide; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast

1998
Endocrine therapy of prostate cancer.
    Cancer treatment and research, 1998, Volume: 94

    Topics: 5-alpha Reductase Inhibitors; Adenocarcinoma; Aminoglutethimide; Androgen Antagonists; Antineoplasti

1998
[Aromatase inhibitors--new possibilities in treatment of breast carcinoma].
    Praxis, 1998, Apr-22, Volume: 87, Issue:17

    Topics: Aminoglutethimide; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols;

1998
Theoretical considerations for the ideal aromatase inhibitor.
    Breast cancer research and treatment, 1998, Volume: 49 Suppl 1

    Topics: Aminoglutethimide; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neopla

1998
Aromatase inhibitors: a dose-response effect?
    Endocrine-related cancer, 1999, Volume: 6, Issue:2

    Topics: Aminoglutethimide; Anastrozole; Animals; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplas

1999
Status of aromatase inhibitors in relation to other breast cancer treatment modalities.
    Endocrine-related cancer, 1999, Volume: 6, Issue:2

    Topics: Aminoglutethimide; Anticarcinogenic Agents; Antineoplastic Agents; Aromatase Inhibitors; Breast Neop

1999
Use of aromatase inhibitors in breast carcinoma.
    Endocrine-related cancer, 1999, Volume: 6, Issue:1

    Topics: Adult; Aminoglutethimide; Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents, Hormo

1999
A summary of second-line randomized studies of aromatase inhibitors.
    The Journal of steroid biochemistry and molecular biology, 2001, Volume: 79, Issue:1-5

    Topics: Aminoglutethimide; Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Drug Toleran

2001
Cancer of the breast. Endocrine and hormonal therapy.
    Major problems in clinical surgery, 1979, Volume: 5

    Topics: Adrenal Cortex Hormones; Adrenalectomy; Adult; Aged; Aminoglutethimide; Antineoplastic Agents; Breas

1979
Management of breast cancer with bone metastases.
    Bone, 1991, Volume: 12 Suppl 1

    Topics: Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms;

1991
[Hormonal treatment of breast tumor].
    La Clinica terapeutica, 1990, Feb-28, Volume: 132, Issue:4

    Topics: Adrenalectomy; Aminoglutethimide; Antineoplastic Agents; Breast Neoplasms; Drug Administration Sched

1990
Aromatase inhibitors in the treatment of advanced breast cancer.
    Cancer treatment reviews, 1989, Volume: 16, Issue:2

    Topics: Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Fadrozole; Female; Human

1989
Fundamental research leading to improved endocrine therapy for breast cancer.
    Journal of steroid biochemistry, 1987, Volume: 27, Issue:1-3

    Topics: Adrenal Cortex Hormones; Aminoglutethimide; Antineoplastic Agents; Breast Neoplasms; Combined Modali

1987
Enzymatic control of estrogen production in human breast cancer: relative significance of aromatase versus sulfatase pathways.
    Annals of the New York Academy of Sciences, 1986, Volume: 464

    Topics: 17-Hydroxysteroid Dehydrogenases; Adrenalectomy; Aminoglutethimide; Androstenedione; Animals; Aromat

1986
Hormone agonists and antagonists in the treatment of hormone sensitive breast and prostate cancer.
    Cancer surveys, 1986, Volume: 5, Issue:3

    Topics: Aminoglutethimide; Androgen Antagonists; Breast Neoplasms; Estrogen Antagonists; Female; Gonadotropi

1986
Aminoglutethimide--a new endocrine therapy in breast cancer. A cancer research review.
    Experimental cell biology, 1985, Volume: 53, Issue:1

    Topics: Adrenal Glands; Aminoglutethimide; Aromatase Inhibitors; Breast Neoplasms; Estrogens; Female; Humans

1985
Could aminoglutethimide replace adrenalectomy?
    Breast cancer research and treatment, 1985, Volume: 6, Issue:3

    Topics: Adrenal Cortex; Adrenalectomy; Aminoglutethimide; Bone Neoplasms; Breast Neoplasms; Clinical Trials

1985

Trials

6 trials available for aminoglutethimide and Hormone-Dependent Neoplasms

ArticleYear
Second-line hormonotherapy for breast cancer. Uselessness of first-line continuation.
    American journal of clinical oncology, 1993, Volume: 16, Issue:6

    Topics: Aged; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; H

1993
Second-line endocrine treatment of advanced breast cancer--a randomized cross-over study of medroxy-progesterone acetate and aminoglutethimide.
    Acta oncologica (Stockholm, Sweden), 1996, Volume: 35 Suppl 5

    Topics: Aminoglutethimide; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cross-Over Studies; Humans; Me

1996
Primary systemic therapy for operable breast cancer--10-year survival data after chemotherapy and hormone therapy.
    British journal of cancer, 1997, Volume: 76, Issue:8

    Topics: Adult; Aged; Aminoglutethimide; Androstenedione; Antineoplastic Combined Chemotherapy Protocols; Axi

1997
Content of epidermal growth factor receptor in metastatic breast cancer: its role in endocrine sensitivity prediction.
    Neoplasma, 2000, Volume: 47, Issue:2

    Topics: Adult; Aminoglutethimide; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Prot

2000
Correlation of breast tumour aromatase activity and response to aromatase inhibition with aminoglutethimide.
    Oncology, 1987, Volume: 44, Issue:6

    Topics: Aminoglutethimide; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Drug Evaluation; Estrogens; Fe

1987
Could aminoglutethimide replace adrenalectomy?
    Breast cancer research and treatment, 1985, Volume: 6, Issue:3

    Topics: Adrenal Cortex; Adrenalectomy; Aminoglutethimide; Bone Neoplasms; Breast Neoplasms; Clinical Trials

1985

Other Studies

23 other studies available for aminoglutethimide and Hormone-Dependent Neoplasms

ArticleYear
Polymer therapeutics designed for a combination therapy of hormone-dependent cancer.
    Angewandte Chemie (International ed. in English), 2005, Jun-27, Volume: 44, Issue:26

    Topics: Aminoglutethimide; Antibiotics, Antineoplastic; Breast Neoplasms; Cell Line, Tumor; Doxorubicin; Dru

2005
Influence of ACTH on aminoglutethimide induced reduction of plasma steroids in postmenopausal breast cancer.
    Journal of steroid biochemistry, 1984, Volume: 21, Issue:3

    Topics: Adrenocorticotropic Hormone; Aminoglutethimide; Breast Neoplasms; Cosyntropin; Drug Therapy, Combina

1984
Treatment of breast carcinoma with aminoglutethimide.
    Acta radiologica. Oncology, 1984, Volume: 23, Issue:6

    Topics: Aminoglutethimide; Breast Neoplasms; Cortisone; Dexamethasone; Drug Resistance; Drug Therapy, Combin

1984
Aminoglutethimide.
    Lancet (London, England), 1981, May-30, Volume: 1, Issue:8231

    Topics: Aged; Aminoglutethimide; Breast Neoplasms; Female; Humans; Menopause; Middle Aged; Neoplasms, Hormon

1981
Cross-over comparison of tamoxifen and aminoglutethimide in advanced breast cancer.
    Cancer research, 1982, Volume: 42, Issue:8 Suppl

    Topics: Aminoglutethimide; Breast Neoplasms; Female; Humans; Hydrocortisone; Menopause; Middle Aged; Neoplas

1982
Endocrine changes associated with relapse in advanced breast cancer patients on aminoglutethimide therapy.
    The Journal of clinical endocrinology and metabolism, 1984, Volume: 58, Issue:1

    Topics: Aminoglutethimide; Androstenedione; Breast Neoplasms; Dehydroepiandrosterone; Estradiol; Estrone; Fe

1984
Introduction to the conference, Aromatase: New Perspectives for Breast Cancer.
    Cancer research, 1982, Volume: 42, Issue:8 Suppl

    Topics: Aminoglutethimide; Animals; Aromatase Inhibitors; Breast Neoplasms; Estrogen Antagonists; Estrogens;

1982
In vivo and in vitro pharmacological studies of aminoglutethimide as an aromatase inhibitor.
    Cancer research, 1982, Volume: 42, Issue:8 Suppl

    Topics: Adrenal Cortex; Aminoglutethimide; Aromatase Inhibitors; Breast Neoplasms; Dexamethasone; Drug Admin

1982
Adequacy of estrogen suppression with aminoglutethimide and hydrocortisone as treatment of human breast cancer: correlation of hormonal data with clinical responses.
    Cancer research, 1982, Volume: 42, Issue:8 Suppl

    Topics: Adrenalectomy; Aminoglutethimide; Androgens; Aromatase Inhibitors; Breast Neoplasms; Carcinoembryoni

1982
Is aminoglutethimide an alternative to adrenalectomy for metastatic carcinoma of the breast?
    Canadian journal of surgery. Journal canadien de chirurgie, 1982, Volume: 25, Issue:6

    Topics: Adrenalectomy; Adult; Aged; Aminoglutethimide; Breast Neoplasms; Drug Therapy, Combination; Female;

1982
Influence of estrogen receptor status on response of metastatic breast cancer to aminoglutethimide therapy.
    Cancer, 1980, Feb-15, Volume: 45, Issue:4

    Topics: Aminoglutethimide; Breast Neoplasms; Female; Humans; Menopause; Middle Aged; Neoplasms, Hormone-Depe

1980
[Aromatase inhibitor].
    Medizinische Monatsschrift fur Pharmazeuten, 1993, Volume: 16, Issue:3

    Topics: Aminoglutethimide; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Estrogens; Female;

1993
Low-dose aminoglutethimide therapy without glucocorticoid administration. Clinical and hormonal findings.
    Oncology, 1992, Volume: 49, Issue:1

    Topics: Aged; Aminoglutethimide; Breast Neoplasms; Female; Glucocorticoids; Hormones; Humans; Menopause; Mid

1992
[Results of hormone therapy with aminoglutethimide (Rodazol) in postmenopausal metastatic breast cancer].
    Geburtshilfe und Frauenheilkunde, 1991, Volume: 51, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aminoglutethimide; Breast Neoplasms; Female; Follow-Up Studies; Huma

1991
[Growth inhibition of MCF-7 human breast cancer cells by aromatase inhibitors].
    Nihon Sanka Fujinka Gakkai zasshi, 1991, Volume: 43, Issue:12

    Topics: Aminoglutethimide; Aromatase Inhibitors; Breast Neoplasms; Cyproterone; Cyproterone Acetate; Female;

1991
Endocrine and clinical aspects of new compounds for treatment of hormone-related cancer in gynecology.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1990, Volume: 118

    Topics: Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Buserelin; Female; Goser

1990
[Experimental multihormone therapy on human breast carcinomas grown in nude mice].
    Nihon Geka Gakkai zasshi, 1989, Volume: 90, Issue:12

    Topics: Aminoglutethimide; Animals; Drug Therapy, Combination; Estrogens; Female; Mammary Neoplasms, Experim

1989
[The effect of aminoglutethimide on steroid synthesis of the adrenal gland and its use in prostate cancer].
    Helvetica chirurgica acta, 1989, Volume: 56, Issue:3

    Topics: Adrenal Cortex; Aged; Aged, 80 and over; Aminoglutethimide; Androgens; Combined Modality Therapy; Hu

1989
[Changes in serum lipoproteins under hormonal therapy of breast carcinoma and other endocrine-dependent tumors].
    Onkologie, 1985, Volume: 8, Issue:2

    Topics: Aminoglutethimide; Breast Neoplasms; Cholesterol; Cortisone; Drug Therapy, Combination; Female; Huma

1985
[Therapeutic results obtained with aminoglutethimide in advanced-stage breast cancer. Factors predictive of a response].
    Acta clinica Belgica. Supplementum, 1986, Volume: 11

    Topics: Adult; Aged; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Es

1986
Clinical studies with aminoglutethimide in advanced breast carcinoma.
    Acta clinica Belgica. Supplementum, 1986, Volume: 11

    Topics: Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Drug Evaluation

1986
[Aminoglutethimide in the treatment of metastasizing breast carcinoma in old age].
    Chirurgia italiana, 1987, Volume: 39, Issue:2

    Topics: Aged; Aged, 80 and over; Aminoglutethimide; Breast Neoplasms; Female; Humans; Menopause; Middle Aged

1987
Aromatase inhibitors and the treatment of breast cancer.
    Journal of steroid biochemistry, 1986, Volume: 24, Issue:1

    Topics: Adult; Aged; Aminoglutethimide; Androstenedione; Animals; Aromatase Inhibitors; Breast Neoplasms; Es

1986