aminoglutethimide has been researched along with Glioma in 2 studies
Aminoglutethimide: An aromatase inhibitor that is used in the treatment of advanced BREAST CANCER.
aminoglutethimide : A dicarboximide that is a six-membered cyclic compound having ethyl and 4-aminophenyl substituents at the 3-position.
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
| Excerpt | Relevance | Reference |
|---|---|---|
| " C6 rat glioma tumor cells in culture biosynthesize both pregnenolone (P) and D." | 3.70 | Detection of P450c17-independent pathways for dehydroepiandrosterone (DHEA) biosynthesis in brain glial tumor cells. ( Cascio, C; Lieberman, S; Lin, YY; Papadopoulos, V; Prasad, VV, 1998) |
| "Incubation of C6 glioma cells in the presence of aminoglutethimide, an inhibitor of cholesterol metabolism, together with either adenosine 3',5'-cyclic monophosphate (cAMP) analogues or agents that increase cAMP synthesis, such as cholera toxin, forskolin, and isoproterenol, stimulated the rate of pregnenolone formation by their isolated mitochondria." | 3.69 | Regulation of C6 glioma cell steroidogenesis by adenosine 3',5'-cyclic monophosphate. ( Guarneri, P; Papadopoulos, V, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Papadopoulos, V | 2 |
| Guarneri, P | 1 |
| Cascio, C | 1 |
| Prasad, VV | 1 |
| Lin, YY | 1 |
| Lieberman, S | 1 |
2 other studies available for aminoglutethimide and Glioma
| Article | Year |
|---|---|
Regulation of C6 glioma cell steroidogenesis by adenosine 3',5'-cyclic monophosphate.
Topics: Adenylyl Cyclases; Aminoglutethimide; Animals; Cyclic AMP; Glioma; Humans; Isoproterenol; Mevalonic | 1994 |
Detection of P450c17-independent pathways for dehydroepiandrosterone (DHEA) biosynthesis in brain glial tumor cells.
Topics: Aminoglutethimide; Animals; Brain Neoplasms; Cholesterol Side-Chain Cleavage Enzyme; Cytochrome P-45 | 1998 |