aminoglutethimide and Glial Cell Tumors studies

aminoglutethimide and Glial Cell Tumors

Aminoglutethimide: An aromatase inhibitor that is used in the treatment of advanced BREAST CANCER.
aminoglutethimide : A dicarboximide that is a six-membered cyclic compound having ethyl and 4-aminophenyl substituents at the 3-position.

Research Excerpts

Excerpt	Relevance	Reference
" C6 rat glioma tumor cells in culture biosynthesize both pregnenolone (P) and D."	3.70	Detection of P450c17-independent pathways for dehydroepiandrosterone (DHEA) biosynthesis in brain glial tumor cells. ( Cascio, C; Lieberman, S; Lin, YY; Papadopoulos, V; Prasad, VV, 1998)
"Incubation of C6 glioma cells in the presence of aminoglutethimide, an inhibitor of cholesterol metabolism, together with either adenosine 3',5'-cyclic monophosphate (cAMP) analogues or agents that increase cAMP synthesis, such as cholera toxin, forskolin, and isoproterenol, stimulated the rate of pregnenolone formation by their isolated mitochondria."	3.69	Regulation of C6 glioma cell steroidogenesis by adenosine 3',5'-cyclic monophosphate. ( Guarneri, P; Papadopoulos, V, 1994)

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (100.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

0 (0.00)

18.7374

1990's

2 (100.00)

18.2507

2000's

0 (0.00)

29.6817

2010's

0 (0.00)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Papadopoulos, V	2
Guarneri, P	1
Cascio, C	1
Prasad, VV	1
Lin, YY	1
Lieberman, S	1

Studies

Papadopoulos, V

Guarneri, P

Cascio, C

Prasad, VV

Lin, YY

Lieberman, S

Other Studies

2 other studies available for aminoglutethimide and Glial Cell Tumors

Article	Year
Regulation of C6 glioma cell steroidogenesis by adenosine 3',5'-cyclic monophosphate. Glia, 1994, Volume: 10, Issue:1 Topics: Adenylyl Cyclases; Aminoglutethimide; Animals; Cyclic AMP; Glioma; Humans; Isoproterenol; Mevalonic	1994
Detection of P450c17-independent pathways for dehydroepiandrosterone (DHEA) biosynthesis in brain glial tumor cells. Proceedings of the National Academy of Sciences of the United States of America, 1998, Mar-17, Volume: 95, Issue:6 Topics: Aminoglutethimide; Animals; Brain Neoplasms; Cholesterol Side-Chain Cleavage Enzyme; Cytochrome P-45	1998

Article

Year

Regulation of C6 glioma cell steroidogenesis by adenosine 3',5'-cyclic monophosphate.

Glia, 1994, Volume: 10, Issue:1

Topics: Adenylyl Cyclases; Aminoglutethimide; Animals; Cyclic AMP; Glioma; Humans; Isoproterenol; Mevalonic

1994

Detection of P450c17-independent pathways for dehydroepiandrosterone (DHEA) biosynthesis in brain glial tumor cells.

Proceedings of the National Academy of Sciences of the United States of America, 1998, Mar-17, Volume: 95, Issue:6

Topics: Aminoglutethimide; Animals; Brain Neoplasms; Cholesterol Side-Chain Cleavage Enzyme; Cytochrome P-45

1998