Page last updated: 2024-10-22

aminoglutethimide and Endometrial Neoplasms

aminoglutethimide has been researched along with Endometrial Neoplasms in 4 studies

Aminoglutethimide: An aromatase inhibitor that is used in the treatment of advanced BREAST CANCER.
aminoglutethimide : A dicarboximide that is a six-membered cyclic compound having ethyl and 4-aminophenyl substituents at the 3-position.

Endometrial Neoplasms: Tumors or cancer of ENDOMETRIUM, the mucous lining of the UTERUS. These neoplasms can be benign or malignant. Their classification and grading are based on the various cell types and the percent of undifferentiated cells.

Research Excerpts

ExcerptRelevanceReference
"Thirty-nine patients of endometrial cancer were treated with hydroxyprogesterone caproate, AG or combination of both, and their effects were compared."2.68[Comparison between the roles of aminoglutethimide and hydroxyprogesterone caproates in the treatment of endometrial cancer]. ( Liu, XS; Zhang, X, 1995)
"AG also can be used to treat endometrial carcinoma."2.68Exploration for drug therapy in endometrial carcinoma. ( Cao, B; Zhang, X, 1996)
"Estrogen receptors of human endometrial cancer Ishikawa cells were found to be present in moderate amounts (160-200 fmol/mg protein), and to specifically bind moxestrol (R2858) with a very high affinity characterized by a Kd around 60 pM, when measured under equilibrium conditions."1.29Lack of estrogenic potential of progesterone- or 19-nor-progesterone-derived progestins as opposed to testosterone or 19-nor-testosterone derivatives on endometrial Ishikawa cells. ( Botella, J; Delansorne, R; Duc, I; Duranti, E; Paris, J; Viader, V, 1995)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (75.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Spano, JP1
Soria, JC1
Kambouchner, M1
Piperno-Neuman, S1
Morin, F1
Morere, JF1
Martin, A1
Breau, JL1
Botella, J1
Duranti, E1
Viader, V1
Duc, I1
Delansorne, R1
Paris, J1
Liu, XS1
Zhang, X2
Cao, B1

Trials

2 trials available for aminoglutethimide and Endometrial Neoplasms

ArticleYear
[Comparison between the roles of aminoglutethimide and hydroxyprogesterone caproates in the treatment of endometrial cancer].
    Zhonghua fu chan ke za zhi, 1995, Volume: 30, Issue:8

    Topics: 17 alpha-Hydroxyprogesterone Caproate; Aminoglutethimide; Antineoplastic Agents, Hormonal; Antineopl

1995
Exploration for drug therapy in endometrial carcinoma.
    Chinese medical journal, 1996, Volume: 109, Issue:5

    Topics: 17 alpha-Hydroxyprogesterone Caproate; Adenocarcinoma; Aged; Aged, 80 and over; Aminoglutethimide; A

1996

Other Studies

2 other studies available for aminoglutethimide and Endometrial Neoplasms

ArticleYear
Long-term survival of patients given hormonal therapy for metastatic endometrial stromal sarcoma.
    Medical oncology (Northwood, London, England), 2003, Volume: 20, Issue:1

    Topics: Adult; Aminoglutethimide; Antineoplastic Agents, Hormonal; Chemotherapy, Adjuvant; Disease-Free Surv

2003
Lack of estrogenic potential of progesterone- or 19-nor-progesterone-derived progestins as opposed to testosterone or 19-nor-testosterone derivatives on endometrial Ishikawa cells.
    The Journal of steroid biochemistry and molecular biology, 1995, Volume: 55, Issue:1

    Topics: Adenocarcinoma; Alkaline Phosphatase; Aminoglutethimide; Aromatase Inhibitors; Binding, Competitive;

1995