Page last updated: 2024-10-22

aminoglutethimide and Disease Models, Animal

aminoglutethimide has been researched along with Disease Models, Animal in 13 studies

Aminoglutethimide: An aromatase inhibitor that is used in the treatment of advanced BREAST CANCER.
aminoglutethimide : A dicarboximide that is a six-membered cyclic compound having ethyl and 4-aminophenyl substituents at the 3-position.

Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Research Excerpts

ExcerptRelevanceReference
" The combination of AGLD (5 mg/kg) with phenobarbital (PB, applied at its subeffective dose of 15 mg/kg) significantly shortened motor seizure and afterdischarge duration in amygdala-kindled seizures."7.73Aminoglutethimide but not spironolactone enhances the anticonvulsant effect of some antiepileptics against amygdala-kindled seizures in rats. ( Borowicz, KK; Czuczwar, SJ, 2005)
" The combination of AGLD (5 mg/kg) with phenobarbital (PB, applied at its subeffective dose of 15 mg/kg) significantly shortened motor seizure and afterdischarge duration in amygdala-kindled seizures."3.73Aminoglutethimide but not spironolactone enhances the anticonvulsant effect of some antiepileptics against amygdala-kindled seizures in rats. ( Borowicz, KK; Czuczwar, SJ, 2005)
"Pleurisy was induced by intrapleural injection of carrageenan in mice pre-treated or not with PK11195."1.32Involvement of steroids in anti-inflammatory effects of PK11195 in a murine model of pleurisy. ( da Silva, MB; Farges, RC; Fröde, TS, 2004)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19904 (30.77)18.7374
1990's0 (0.00)18.2507
2000's4 (30.77)29.6817
2010's2 (15.38)24.3611
2020's3 (23.08)2.80

Authors

AuthorsStudies
Solinski, HJ1
Dranchak, P1
Oliphant, E1
Gu, X1
Earnest, TW1
Braisted, J1
Inglese, J1
Hoon, MA1
Abrams, RPM1
Yasgar, A1
Teramoto, T1
Lee, MH1
Dorjsuren, D1
Eastman, RT1
Malik, N1
Zakharov, AV1
Li, W1
Bachani, M1
Brimacombe, K1
Steiner, JP1
Hall, MD1
Balasubramanian, A1
Jadhav, A1
Padmanabhan, R1
Simeonov, A1
Nath, A1
Holanda, VAD1
Oliveira, MC1
da Silva Junior, ED1
Gavioli, EC1
Bencze, M1
Vavřínová, A1
Zicha, J1
Behuliak, M1
Harvey, PW1
da Silva, MB1
Farges, RC1
Fröde, TS1
Borowicz, KK1
Czuczwar, SJ1
Yuan, HB1
Huang, Y1
Zheng, S1
Zuo, Z1
Watanabe, S1
Yamakami, J1
Tsuchiya, M1
Terajima, T1
Kizu, J1
Hori, S1
Shessel, FS1
Block, NL1
Stover, B1
Claflin, A1
Malinin, TI1
Politano, VA1
McGuire, WL1
Chamness, GC1
Horwitz, KB1
Zava, DT1
Goldman, AS2

Reviews

2 reviews available for aminoglutethimide and Disease Models, Animal

ArticleYear
Adrenocortical endocrine disruption.
    The Journal of steroid biochemistry and molecular biology, 2016, Volume: 155, Issue:Pt B

    Topics: Adrenal Cortex; Adrenal Insufficiency; Aminoglutethimide; Animals; Cell Line, Tumor; Corticosterone;

2016
Prolactin and estrogen receptors in breast cancer.
    Pathobiology annual, 1977, Volume: 7

    Topics: Aminoglutethimide; Animals; Breast Neoplasms; Dexamethasone; Disease Models, Animal; Estrogen Antago

1977

Other Studies

11 other studies available for aminoglutethimide and Disease Models, Animal

ArticleYear
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
    Science translational medicine, 2019, 07-10, Volume: 11, Issue:500

    Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S

2019
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr

2020
Tamsulosin facilitates depressive-like behaviors in mice: Involvement of endogenous glucocorticoids.
    Brain research bulletin, 2022, Volume: 178

    Topics: Adaptation, Psychological; Adrenergic alpha-1 Receptor Antagonists; Aminoglutethimide; Animals; Arom

2022
Pharmacological suppression of endogenous glucocorticoid synthesis attenuated blood pressure and heart rate response to acute restraint in Wistar rats.
    Physiological research, 2020, 07-16, Volume: 69, Issue:3

    Topics: Adrenalectomy; Aminoglutethimide; Animals; Antimetabolites; Aromatase Inhibitors; Blood Pressure; Di

2020
Involvement of steroids in anti-inflammatory effects of PK11195 in a murine model of pleurisy.
    Mediators of inflammation, 2004, Volume: 13, Issue:2

    Topics: Adenosine Deaminase; Aminoglutethimide; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Ca

2004
Aminoglutethimide but not spironolactone enhances the anticonvulsant effect of some antiepileptics against amygdala-kindled seizures in rats.
    Journal of neural transmission (Vienna, Austria : 1996), 2005, Volume: 112, Issue:7

    Topics: Adrenergic Agents; Aminoglutethimide; Amygdala; Animals; Anticonvulsants; Clonazepam; Disease Models

2005
Hypothermic preconditioning reduces Purkinje cell death possibly by preventing the over-expression of inducible nitric oxide synthase in rat cerebellar slices after an in vitro simulated ischemia.
    Neuroscience, 2006, Oct-13, Volume: 142, Issue:2

    Topics: Aminoglutethimide; Analysis of Variance; Animals; Blotting, Western; Cell Death; Cerebellum; Disease

2006
Anti-inflammatory effect of theophylline in rats and its involvement of the glucocorticoid-glucocorticoid receptor system.
    Journal of pharmacological sciences, 2008, Volume: 106, Issue:4

    Topics: Aminoglutethimide; Animals; Anti-Inflammatory Agents; Carrageenan; Disease Models, Animal; Dose-Resp

2008
Endocrine manipulation of the Dunning prostatic adenocarcinoma.
    Investigative urology, 1980, Volume: 17, Issue:6

    Topics: Adenocarcinoma; Adrenalectomy; Aminoglutethimide; Animals; Castration; Diethylstilbestrol; Disease M

1980
Production of congenital lipoid adrenal hyperplasia in rats and inhibition of cholesterol side-chain cleavage.
    Endocrinology, 1970, Volume: 86, Issue:6

    Topics: Adrenal Glands; Adrenal Hyperplasia, Congenital; Aminoglutethimide; Aniline Compounds; Animals; Anti

1970
Experimental congenital lipoid adrenal hyperplasia: prevention of anatomic defects produced by aminoglutethimide.
    Endocrinology, 1970, Volume: 87, Issue:5

    Topics: Adrenal Glands; Adrenal Hyperplasia, Congenital; Aminoglutethimide; Aniline Compounds; Animals; Anti

1970