Page last updated: 2024-10-22

aminoglutethimide and Cushing Syndrome

aminoglutethimide has been researched along with Cushing Syndrome in 77 studies

Aminoglutethimide: An aromatase inhibitor that is used in the treatment of advanced BREAST CANCER.
aminoglutethimide : A dicarboximide that is a six-membered cyclic compound having ethyl and 4-aminophenyl substituents at the 3-position.

Cushing Syndrome: A condition caused by prolonged exposure to excess levels of cortisol (HYDROCORTISONE) or other GLUCOCORTICOIDS from endogenous or exogenous sources. It is characterized by upper body OBESITY; OSTEOPOROSIS; HYPERTENSION; DIABETES MELLITUS; HIRSUTISM; AMENORRHEA; and excess body fluid. Endogenous Cushing syndrome or spontaneous hypercortisolism is divided into two groups, those due to an excess of ADRENOCORTICOTROPIN and those that are ACTH-independent.

Research Excerpts

ExcerptRelevanceReference
"Fifteen patients with endogenous Cushing's syndrome were treated with metyrapone and/or amino-glutethimide."9.05Aminoglutethimide and metyrapone in the management of Cushing's syndrome. ( Adamson, U; Sjöberg, HE; Thorén, M, 1985)
"The adrenostatic effect of metyrapone (Metopiron) and aminoglutethimide (Orimeten) was assessed retrospectively in ten patients with ACTH-dependent Cushing's syndrome, four of them with the ectopic form."7.67[Adrenostatic treatment of ACTH-dependent Cushing syndrome using metyrapone and aminoglutethimide]. ( Allolio, B; Jaursch-Hancke, C; Kaulen, D; Reincke, M; Winkelmann, W, 1987)
"Eighteen patients with Cushing's syndrome (16 pituitary-dependent Cushing's disease, 1 ectopic ACTH syndrome, 1 primary adrenal adenoma) were given a combination of aminoglutethimide and metyrapone, with the object of controlling cortisol overproduction using less toxic doses than would be required with each drug alone."7.65Drug controlled of Cushing's syndrome. Combined aminoglutethimide and metyrapone therapy. ( Burke, CW; Burley, DM; Child, DF; Fraser, TR; Rees, LH, 1976)
"Fifteen patients with endogenous Cushing's syndrome were treated with metyrapone and/or amino-glutethimide."5.05Aminoglutethimide and metyrapone in the management of Cushing's syndrome. ( Adamson, U; Sjöberg, HE; Thorén, M, 1985)
"Inhibitors of steroid synthesis such as o,p'-DDD, aminoglutethimide, metyrapone, trilostane and ketoconazole are usually used for treatment of Cushing's syndrome in order to reduce the steroid production in the patients showing several complications, including severe hypertension and diabetes mellitus, and also an incomplete remission after the surgical treatment."4.79[Clinical usefulness of pharmacological treatment of Cushing's syndrome]. ( Nishikawa, T; Saito, J, 1994)
"Surgery with immediate adjuvant long term mitotane administration was the most effective form of therapy for patients with adrenocortical carcinoma."3.69Adrenocortical carcinoma. A clinical study and treatment results of 52 patients. ( Kasperlik-Załuska, AA; Makowska, AM; Migdalska, BM; Zgliczyński, S, 1995)
"The adrenostatic effect of metyrapone (Metopiron) and aminoglutethimide (Orimeten) was assessed retrospectively in ten patients with ACTH-dependent Cushing's syndrome, four of them with the ectopic form."3.67[Adrenostatic treatment of ACTH-dependent Cushing syndrome using metyrapone and aminoglutethimide]. ( Allolio, B; Jaursch-Hancke, C; Kaulen, D; Reincke, M; Winkelmann, W, 1987)
"Eighteen patients with Cushing's syndrome (16 pituitary-dependent Cushing's disease, 1 ectopic ACTH syndrome, 1 primary adrenal adenoma) were given a combination of aminoglutethimide and metyrapone, with the object of controlling cortisol overproduction using less toxic doses than would be required with each drug alone."3.65Drug controlled of Cushing's syndrome. Combined aminoglutethimide and metyrapone therapy. ( Burke, CW; Burley, DM; Child, DF; Fraser, TR; Rees, LH, 1976)
"Thus, we should treat Cushing's syndrome as soon as possible, since many complications, including cardiovascular diseases and infections, will soon occur when the definite diagnosis is delayed."2.44[Medical treatment for Cushing's syndrome]. ( Nishikawa, T; Omura, M; Saito, J, 2008)
"Cushing syndrome is documented by laboratory examinations."1.26The treatment of ACTH Paraneoplastic syndrome with aminoglutethimide. ( Banks, D; Chapman, J; Chinn, B; Pearson, S; Vaughn, CB, 1979)
"Amelioration of the hypercortisolism occurred after removal of the bronchial adenoma."1.25Cushing's syndrome associated with a bronchial adenoma. Possible periodic hormonogenesis. ( Bruderman, I; Griffel, WB; Gutman, A; Myers, B; Shapiro, MS, 1975)

Research

Studies (77)

TimeframeStudies, this research(%)All Research%
pre-199061 (79.22)18.7374
1990's12 (15.58)18.2507
2000's4 (5.19)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Leal-Cerro, A1
Soto Moreno, A1
Mangas, MA1
León Justel, A1
Webb, S1
Vong, CH1
Forest, M1
Nicolino, M1
Nishikawa, T2
Saito, J2
Omura, M1
Gillis, D1
Rösler, A1
Hannon, TS1
Koplewitz, BZ1
Hirsch, HJ1
Schteingart, DE2
Conn, JW2
Gogel, EL1
Salber, PR1
Tyrrell, JB1
Rosenblum, ML1
Findling, JW1
Jacobelli, A2
Agostino, A1
Altomonte, G1
Van Gaal, L1
Delvigne, C1
Abs, R1
De Leeuw, I1
Bekaert, J1
Bergstrand, CG1
Nilsson, KO1
Kasperlik-Załuska, A4
Migdalska, B4
Krieger, DT1
Chen, JL1
Bricaire, H4
Luton, JP3
Miller, JW1
Crapo, L1
Freeman, DA1
Solomon, CG1
Dluhy, RG1
Kasperlik-Załuska, AA1
Migdalska, BM1
Zgliczyński, S1
Makowska, AM1
Miura, K2
Stratakis, CA1
Chrousos, GP1
Engelhardt, D2
Weber, MM1
Kishi, DT1
Child, DF1
Burke, CW1
Burley, DM2
Rees, LH1
Fraser, TR1
Ghnassia, JP1
Neri, V2
Schieppati, G1
Rondena, M1
Cozzi, C1
Vaughn, CB1
Pearson, S1
Chapman, J1
Chinn, B1
Banks, D1
Ross, WM1
Evered, DC1
Hunter, P1
Benaim, M1
Cook, D1
Hall, R2
Neumann, P1
Knappe, G1
Stahl, F1
Kublun, G1
Bruns, W1
Wulfert, P1
Koelmeyer, TD1
Woods, WP1
McElduff, A1
Clifton-Bligh, P1
Posen, S1
deAsis, DN1
Samaan, NA1
Marek, J1
Motlik, K2
Zachmann, M1
Gitzelmann, RP1
Zagalak, M1
Prader, A1
Scott, RD1
Shapiro, MS1
Gutman, A1
Bruderman, I1
Myers, B1
Griffel, WB1
Kong, HL1
Lee, KO1
Cheah, JS1
Murphy, BE1
Schramm, J1
Wüster, C1
Jeske, W2
Wiśniewska-Woźniak, T2
Sek, S1
Pan, CY1
Luo, GC1
Li, JY1
Wang, YZ1
Lu, SZ1
Ma, SQ1
Guo, AY1
Reincke, M1
Allolio, B1
Jaursch-Hancke, C1
Kaulen, D1
Winkelmann, W1
Thorén, M1
Adamson, U1
Sjöberg, HE1
Carey, RM1
Orth, DN2
Hartmann, WH1
Gorden, P1
Becker, CE1
Levey, GS1
Roth, J1
Pinsker, P1
Stárka, L2
Hradec, E1
Horký, K3
Küchel, O4
Gregorová, I2
Jiránková, J2
Matys, Z2
Gregorvá, I1
Fishman, LM1
Liddle, GW2
Island, DP1
Fleischer, N1
Smilo, RP1
Earll, JM1
Forsham, PH1
Cash, R2
Brough, AJ1
Cohen, MN1
Satoh, PS1
Brun, J1
Revol, A1
Queneau, P1
Melby, JC1
Raith, L1
Borgia, MC1
Borgia, C1
Sellini, M1
Touitou, Y1
Legrand, JC1
Desgrez, P1
Aida, M1
Hunter, PR1
Ross, W1
Cook, DB1
Odagiri, E1
Yamaguchi, H1
Idemura, H1
Idemura, R1
Suda, T1
Hanson, TJ1
Ballonoff, LB1
Northcutt, RC1
Felt, V1
Geyer, G1
Schmitt, KW1
Juselius, R1
Hanlon, J1
Steed, D1
Givens, JR1
Camacho, A1
Patterson, P1
Hughss, SW1
Raggatt, PR1
Engel, LL1
Symington, T1
Hamilton, W1
Albeaux-Fernet, M1
Lumbroso, P1
Netter, A1
Sebaoun, J1
Barnett, IG1
Nabarro, JD1
LeQuesne, LP1
Faglia, G1
Gattinoni, L1
Travaglini, P1
Acerbi, L1
Ambrosi, B1
Philbert, M1
Mathieu de Fossey, B1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
An Open-label Study of the Efficacy and Safety of CORLUX (Mifepristone) in the Treatment of the Signs and Symptoms of Endogenous Cushing's Syndrome[NCT00569582]Phase 350 participants (Actual)Interventional2007-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Decrease in Diastolic Blood Pressure.

Responder is defined as subject with a decrease greater than or equal to 5mm Hg in diastolic blood pressure from baseline to week 24 or last visit. (NCT00569582)
Timeframe: Baseline to Week 24

Interventionparticipants (Number)
Mifepristone8

Improvement in Diabetes and/or Glucose Intolerance.

Responder is defined as subject with a decrease greater than or equal to 25% in area under the curve for glucose on 2-hour oral glucose test from baseline to week 24 or last visit, for Cushing's patients with type-2 diabetes mellitus/impaired glucose tolerance. (NCT00569582)
Timeframe: Baseline to Week 24

Interventionparticipants (Number)
Mifepristone15

Reviews

13 reviews available for aminoglutethimide and Cushing Syndrome

ArticleYear
[The medical management of Cushing's syndrome].
    Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion, 2009, Volume: 56, Issue:4

    Topics: Adrenal Cortex; Adrenalectomy; Adrenocorticotropic Hormone; Aminoglutethimide; Combined Modality The

2009
[Medical treatment for Cushing's syndrome].
    Nihon rinsho. Japanese journal of clinical medicine, 2008, Volume: 66, Issue:1

    Topics: Aminoglutethimide; Aromatase Inhibitors; Cushing Syndrome; Humans; Ketoconazole; Metyrapone; Steroid

2008
Treatment of Cushing's disease in children.
    Acta paediatrica Scandinavica, 1982, Volume: 71, Issue:1

    Topics: Adrenalectomy; Adrenocorticotropic Hormone; Aminoglutethimide; Bromocriptine; Child; Cushing Syndrom

1982
Pathophysiology and treatment of Cushing's disease.
    Progress in clinical and biological research, 1982, Volume: 87

    Topics: Adrenal Glands; Adrenalectomy; Aminoglutethimide; Cushing Syndrome; Delayed-Action Preparations; Hum

1982
The medical treatment of Cushing's syndrome.
    Endocrine reviews, 1993, Volume: 14, Issue:4

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Aminoglutethimide; Animals; Bromocriptine; Cushing Syndrom

1993
[Non-invasive therapy of Cushing's syndrome].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1994, Sep-10, Volume: 83, Issue:9

    Topics: Aminoglutethimide; Betamethasone; Bromocriptine; Clinical Trials as Topic; Cushing Syndrome; Cyprohe

1994
Steroid biosynthesis inhibitors in Cushing's syndrome.
    The Clinical investigator, 1994, Volume: 72, Issue:7

    Topics: Adrenal Cortex Hormones; Aminoglutethimide; Cushing Syndrome; Dihydrotestosterone; Etomidate; Humans

1994
Therapy of Cushing's syndrome with steroid biosynthesis inhibitors.
    The Journal of steroid biochemistry and molecular biology, 1994, Volume: 49, Issue:4-6

    Topics: 3-Hydroxysteroid Dehydrogenases; Aminoglutethimide; Cushing Syndrome; Dihydrotestosterone; Etomidate

1994
[Clinical usefulness of pharmacological treatment of Cushing's syndrome].
    Nihon rinsho. Japanese journal of clinical medicine, 1994, Volume: 52, Issue:3

    Topics: Administration, Oral; Aminoglutethimide; Cushing Syndrome; Dihydrotestosterone; Humans; Ketoconazole

1994
Current therapeutic concepts--Cushing's syndrome.
    Journal of the American Pharmaceutical Association, 1975, Volume: 15, Issue:5

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocorticotropic Hormone; Aminoglutethimide; Ci

1975
[Agents inhibiting steroid biosynthesis--aminoglutethimide and o,p'-DDD].
    Nihon rinsho. Japanese journal of clinical medicine, 1974, Nov-10, Volume: 32, Issue:11

    Topics: Adrenal Cortex; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aminogl

1974
[Cushing's syndrome].
    Annals of the New York Academy of Sciences, 1973, Jun-15, Volume: 214

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Aminoglutethimide; Cushing Syndrome

1973
Aminoglutethimide: a "side-effect" turned to therapeutic advantage.
    Postgraduate medical journal, 1970, Volume: 46, Issue:537

    Topics: Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Insufficiency; Adrenocortical Hyperfunctio

1970

Trials

7 trials available for aminoglutethimide and Cushing Syndrome

ArticleYear
Treatment of major depression with steroid suppressive drugs.
    The Journal of steroid biochemistry and molecular biology, 1991, Volume: 39, Issue:2

    Topics: Adrenocortical Hyperfunction; Adult; Aged; Aminoglutethimide; Cushing Syndrome; Depressive Disorder;

1991
[Role of aminoglutethimide in the treatment of adrenal hyperfunction].
    Polskie Archiwum Medycyny Wewnetrznej, 1986, Volume: 76, Issue:5-6

    Topics: Adolescent; Adult; Aminoglutethimide; Child; Clinical Trials as Topic; Cushing Syndrome; Female; Hum

1986
Aminoglutethimide and metyrapone in the management of Cushing's syndrome.
    Acta endocrinologica, 1985, Volume: 109, Issue:4

    Topics: ACTH Syndrome, Ectopic; Adolescent; Adrenal Gland Neoplasms; Adult; Aminoglutethimide; Clinical Tria

1985
Qualitative alterations in urinary 17-ketosteroid excretion during aminoglutethimide administration.
    The Journal of clinical endocrinology and metabolism, 1969, Volume: 29, Issue:2

    Topics: 17-Ketosteroids; Adrenocortical Hyperfunction; Aminoglutethimide; Androsterone; Aniline Compounds; A

1969
Aminoglutethimide (Elipten-Ciba) as an inhibitor of adrenal steroidogenesis: mechanism of action and therapeutic trial.
    The Journal of clinical endocrinology and metabolism, 1967, Volume: 27, Issue:9

    Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aminoglutethimide; Anim

1967
[Use of aminoglutethimide in the treatment of Cushing's syndrome].
    Minerva medica, 1974, Jan-17, Volume: 65, Issue:3

    Topics: 17-Hydroxycorticosteroids; Adrenocorticotropic Hormone; Aminoglutethimide; Clinical Trials as Topic;

1974
Effect of aminoglutethimide and reserpine on the human pituitary-adrenal axis: remission of a case of Cushing's disease.
    Metabolism: clinical and experimental, 1970, Volume: 19, Issue:10

    Topics: 17-Hydroxycorticosteroids; Addison Disease; Adrenal Glands; Adult; Aldosterone; Aminoglutethimide; A

1970

Other Studies

57 other studies available for aminoglutethimide and Cushing Syndrome

ArticleYear
Ketoconazole treatment for Cushing syndrome in McCune-Albright syndrome.
    The Journal of pediatrics, 2009, Volume: 154, Issue:3

    Topics: Adrenergic Agents; Adrenocorticotropic Hormone; Aminoglutethimide; Antifungal Agents; Chemical and D

2009
Prolonged remission of severe Cushing syndrome without adrenalectomy in an infant with McCune-Albright syndrome.
    The Journal of pediatrics, 2008, Volume: 152, Issue:6

    Topics: Adrenalectomy; Adrenergic Agents; Aminoglutethimide; Child; Cushing Syndrome; Enzyme Inhibitors; Fem

2008
Effects of aminoglutethimide upon adrenal function and cortisol metabolism in Cushing's syndrome.
    The Journal of clinical endocrinology and metabolism, 1967, Volume: 27, Issue:12

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Glands; Adrenocortical Hyperfunction

1967
Cushing's disease in a patient with a 'nonfunctioning' pituitary tumor. Spontaneous development and remission.
    Archives of internal medicine, 1983, Volume: 143, Issue:5

    Topics: Adenoma, Chromophobe; Adrenocorticotropic Hormone; Adult; Aminoglutethimide; Cushing Syndrome; Femal

1983
[Treatment of glycoactive hypercorticism].
    La Clinica terapeutica, 1984, Nov-30, Volume: 111, Issue:4

    Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; A

1984
Cushing's syndrome, due to ectopic ACTH-secretion, successfully treated with aminoglutethimide, radiotherapy and chemotherapy.
    Acta clinica Belgica, 1981, Volume: 36, Issue:3

    Topics: Adrenocorticotropic Hormone; Adult; Aminoglutethimide; Carcinoma, Small Cell; Cushing Syndrome; Huma

1981
[Aminoglutethimide in the treatment of Cushing's syndrome (observation of 10 cases)].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1983, Mar-14, Volume: 38, Issue:11

    Topics: 17-Hydroxycorticosteroids; Adult; Aminoglutethimide; Cushing Syndrome; Dose-Response Relationship, D

1983
[Preliminary results of treatment of hypercorticism with aminoglutethimide].
    Zhonghua nei ke za zhi, 1982, Volume: 21, Issue:12

    Topics: Adolescent; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocortical Hyperfunction; Adult; Aminoglute

1982
Aminoglutethimide pretreatment before surgery and pituitary irradiation in Cushing's disease.
    Endokrynologia Polska, 1982, Volume: 33, Issue:1-3

    Topics: Adrenalectomy; Adult; Aminoglutethimide; Cushing Syndrome; Female; Humans; Hydrocortisone; Pituitary

1982
Aminoglutethimide.
    The Medical letter on drugs and therapeutics, 1981, Aug-07, Volume: 23, Issue:16

    Topics: Adult; Aminoglutethimide; Breast Neoplasms; Cushing Syndrome; Female; Humans

1981
[Cushing's syndrome. Medical treatment of adrenal hypercorticism].
    Hormone research, 1980, Volume: 13, Issue:4-5

    Topics: Adrenal Gland Neoplasms; Aminoglutethimide; Androstanols; Bromocriptine; Cushing Syndrome; Cyprohept

1980
Adrenal carcinoma.
    Current therapy in endocrinology and metabolism, 1994, Volume: 5

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Aminoglutethimide; Carcinoma; Cushing Syndrome; Dia

1994
Paraneoplastic endocrine syndromes.
    Current therapy in endocrinology and metabolism, 1994, Volume: 5

    Topics: Acromegaly; Adrenocorticotropic Hormone; Aminoglutethimide; Bromocriptine; Calcitonin; Cushing Syndr

1994
Adrenocortical carcinoma. A clinical study and treatment results of 52 patients.
    Cancer, 1995, May-15, Volume: 75, Issue:10

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Cortex Neoplasms; Adrenocortical Car

1995
Capillaritis (purpura simplex) associated with use of aminoglutethimide in Cushing's syndrome.
    American journal of hospital pharmacy, 1994, Oct-15, Volume: 51, Issue:20

    Topics: Aminoglutethimide; Cushing Syndrome; Drug Eruptions; Female; Humans; Middle Aged; Purpura; Time Fact

1994
Drug controlled of Cushing's syndrome. Combined aminoglutethimide and metyrapone therapy.
    Acta endocrinologica, 1976, Volume: 82, Issue:2

    Topics: Adrenocorticotropic Hormone; Aminoglutethimide; Cushing Syndrome; Dexamethasone; Drug Evaluation; Dr

1976
[Medical treatment and Cushing's disease].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1977, Jun-23, Volume: 53, Issue:24

    Topics: Aminoglutethimide; Bromocriptine; Cushing Syndrome; Cyproheptadine; Humans; Mitotane

1977
[Use of aminoglutethimide in a case of Cushing's syndrome due to ectopic ACTH production].
    La Clinica terapeutica, 1977, Oct-31, Volume: 83, Issue:2

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aminoglutethimide; Cushing Syndrome; Humans; Male; Midd

1977
The treatment of ACTH Paraneoplastic syndrome with aminoglutethimide.
    Journal of the National Medical Association, 1979, Volume: 71, Issue:1

    Topics: Adrenocorticotropic Hormone; Aminoglutethimide; Carcinoma, Small Cell; Cushing Syndrome; Female; Hum

1979
Treatment of Cushing's disease with adrenal blocking drugs and megavoltage therapy to the pituitary.
    Clinical radiology, 1979, Volume: 30, Issue:2

    Topics: Adrenocorticotropic Hormone; Adult; Age Factors; Aged; Aminoglutethimide; Cushing Syndrome; Female;

1979
[The effect of aminoglutethimide in the treatment of adrenal gland hyperfunction].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1979, May-01, Volume: 34, Issue:9

    Topics: Adenoma; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Adult; Aminoglutethimide; Cushin

1979
Carcinoma of the lung presenting as Cushing's syndrome.
    The New Zealand medical journal, 1977, Jan-12, Volume: 85, Issue:579

    Topics: Aminoglutethimide; Carcinoma, Bronchogenic; Cortisone; Cushing Syndrome; Cyclophosphamide; Diagnosis

1977
Metastatic medullary carcinoma of the thyroid complicated by Cushing's syndrome.
    The Medical journal of Australia, 1979, Mar-10, Volume: 1, Issue:5

    Topics: Adult; Aminoglutethimide; Carcinoma; Cushing Syndrome; Dexamethasone; Drug Therapy, Combination; Hum

1979
Feminizing adrenocortical carcinoma with Cushing's syndrome and pseudohyperparathyroidism.
    Archives of internal medicine, 1978, Volume: 138, Issue:2

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adult

1978
Ultrastructural changes of the adrenal cortex in Cushing's syndrome treated with aminoglutethimide (Elipten Ciba)
    Virchows Archiv. B, Cell pathology, 1975, Volume: 18, Issue:2

    Topics: Adrenal Cortex; Adrenal Glands; Aminoglutethimide; Cushing Syndrome; Endoplasmic Reticulum; Histiocy

1975
Effect of aminoglutethimide on urinary cortisol and cortisol metabolites in adolescents with Cushing's syndrome.
    Clinical endocrinology, 1977, Volume: 7, Issue:1

    Topics: Adolescent; Aminoglutethimide; Cushing Syndrome; Female; Humans; Hydrocortisone; Male; Time Factors

1977
Treatment of an adrenal cortical carcinoma with a combination of o,p'-DDD and aminoglutethimide.
    Postgraduate medical journal, 1975, Volume: 51, Issue:591

    Topics: 11-Hydroxycorticosteroids; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenalectomy; Adult;

1975
Cushing's syndrome associated with a bronchial adenoma. Possible periodic hormonogenesis.
    Israel journal of medical sciences, 1975, Volume: 11, Issue:9

    Topics: Adenoma; Adrenalectomy; Adult; Aminoglutethimide; Bronchial Neoplasms; Cushing Syndrome; Dexamethaso

1975
Medical treatment of Cushing's syndrome with aminoglutethimide and ketoconazole.
    Singapore medical journal, 1992, Volume: 33, Issue:5

    Topics: Adenoma; Adrenal Gland Neoplasms; Aminoglutethimide; Cushing Syndrome; Humans; Hydrocortisone; Ketoc

1992
[Inhibited depressive syndrome in a patient with Cushing disease and anterior hypophysial insufficiency].
    Der Nervenarzt, 1991, Volume: 62, Issue:3

    Topics: Aminoglutethimide; Cushing Syndrome; Depressive Disorder; Empty Sella Syndrome; Female; Humans; Hydr

1991
The relationship between cortisol and ACTH in patients with Cushing's disease following neurosurgery or pharmacotherapy.
    Endokrynologia Polska, 1989, Volume: 40, Issue:2

    Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Aminoglutethimide; Cushing Syndrome; Cyproheptadine;

1989
Effects of aminoglutethimide on hypothalamic-pituitary-adrenal functions.
    Chinese medical journal, 1989, Volume: 102, Issue:11

    Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Aminoglutethimide; Child; Cushing Syndrome; Female;

1989
[Adrenostatic treatment of ACTH-dependent Cushing syndrome using metyrapone and aminoglutethimide].
    Deutsche medizinische Wochenschrift (1946), 1987, Oct-02, Volume: 112, Issue:40

    Topics: Adolescent; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aged; Aminoglutethimide; Cushing Syn

1987
Malignant melanoma with ectopic production of adrenocorticotropic hormone. Palliative treatment with inhibitors of adrenal steroid biosynthesis.
    The Journal of clinical endocrinology and metabolism, 1973, Volume: 36, Issue:3

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocortical Hyperfunction; Adrenocorticotropic Hormon

1973
Efficacy of amino-glutethimide in the ectopic ACTH syndrome.
    The Journal of clinical endocrinology and metabolism, 1968, Volume: 28, Issue:6

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocorticotropic Hormone; Adult; Aminoglutethimide; A

1968
Effects of aminoglutethimide (Elipten Ciba), a steroid biosynthesis blocking agent, on adrenal glands in Cushing's syndrome.
    Virchows Archiv. A, Pathology. Pathologische Anatomie, 1973, Volume: 360, Issue:1

    Topics: Acid Phosphatase; Adolescent; Adrenal Glands; Adult; Aminoglutethimide; Cholesterol; Cushing Syndrom

1973
[Clinical experiences with aminoglutethimide (Elipten), a new inhibitor of steroid biosynthesis in the adrenal gland].
    Schweizerische medizinische Wochenschrift, 1968, Nov-23, Volume: 98, Issue:47

    Topics: Adrenal Gland Neoplasms; Adrenal Glands; Adrenal Rest Tumor; Adult; Aminoglutethimide; Aniline Compo

1968
Effects of amino-glutethimide on adrenal function in man.
    The Journal of clinical endocrinology and metabolism, 1967, Volume: 27, Issue:4

    Topics: 17-Hydroxycorticosteroids; Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hor

1967
Suppression of tumorous adrenal hyperfunction by aminoglutethimide.
    Metabolism: clinical and experimental, 1967, Volume: 16, Issue:4

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma; Adrenal Gland Neoplasms; Adrenocortical Hyperfu

1967
[Broncho-pulmonary cancer with true or degraded hypercorticism].
    La Presse medicale, 1969, Nov-29, Volume: 77, Issue:51

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocortical Hyperfunction; Adrenocorticotropic Hormon

1969
Results of treatment in 108 patients with Cushing's syndrome.
    The New England journal of medicine, 1971, Jul-29, Volume: 285, Issue:5

    Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenalectomy; Adrenocorticotropic Hormone; Adult; Age

1971
Therapeutic possibilities in Cushing's syndrome.
    The New England journal of medicine, 1971, Jul-29, Volume: 285, Issue:5

    Topics: Adrenalectomy; Adrenocorticotropic Hormone; Aminoglutethimide; Cushing Syndrome; Hormones, Ectopic;

1971
[Medical therapy of hyperadrenalism].
    Minerva medica, 1973, Mar-14, Volume: 64, Issue:14

    Topics: Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Aminoglutethimide; Cushing Syndrome; Huma

1973
Adrenocortical steroidogenesis and aminoglutethimide (A. G.). II. Cytochemical and ultrastructural changes. Pratical and theoretical values.
    Biomedicine / [publiee pour l'A.A.I.C.I.G.], 1973, Volume: 18, Issue:4

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocortical Hyperfunction; Adrenocorticotropic

1973
Treatment of Cushing's disease with adrenal blocking drugs and megavoltage therapy to the pituitary.
    Proceedings of the Royal Society of Medicine, 1974, Volume: 67, Issue:12 Pt 1

    Topics: Adrenal Gland Diseases; Adrenocorticotropic Hormone; Adult; Aminoglutethimide; Cushing Syndrome; Fem

1974
[Proceedings: Case of Cushing's syndrome with remarkable improvement observed with administration of aminoglutethimide].
    Nihon Naibunpi Gakkai zasshi, 1974, Feb-20, Volume: 50, Issue:2

    Topics: Aminoglutethimide; Cushing Syndrome; Female; Humans; Middle Aged

1974
Letter: Amino-glutethimide and pregnancy.
    JAMA, 1974, Nov-18, Volume: 230, Issue:7

    Topics: Adult; Aminoglutethimide; Cushing Syndrome; Female; Fetus; Gestational Age; Humans; Infant, Newborn;

1974
Effect of aminoglutethimide on adrenal cholesterol in patients with Cushing's syndrome.
    Endocrinologia experimentalis, 1973, Volume: 7, Issue:4

    Topics: Adrenal Glands; Aminoglutethimide; Cholesterol; Cushing Syndrome; Humans; Hydrolysis; Tritium

1973
Values for urinary free cortisol during treatment with amino-glutethimide for Cushing's syndrome.
    Clinical chemistry, 1973, Volume: 19, Issue:9

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Aminoglutethimide; Cushing Syndrome; Dose-Response Relat

1973
Fatty acid composition of the sterol ester fraction of human adrenal cortex in Cushingś syndrome and after treatment with aminoglutethimide.
    Lipids, 1972, Volume: 7, Issue:7

    Topics: Adrenal Cortex Hormones; Adrenal Glands; Aminoglutethimide; Aniline Compounds; Anticonvulsants; Arac

1972
The treatment of congenital adrenal hyperplasia with aminoglutethimide.
    The Quarterly journal of medicine, 1971, Volume: 40, Issue:160

    Topics: Adrenal Hyperplasia, Congenital; Adrenocortical Hyperfunction; Aminoglutethimide; Aniline Compounds;

1971
[Present knowledge on the treatment of Cushing's syndrome].
    La Presse medicale, 1969, Nov-01, Volume: 77, Issue:46

    Topics: Adrenalectomy; Adrenocortical Hyperfunction; Aminoglutethimide; Cushing Syndrome; Dichlorodiphenyldi

1969
Fluctuating Cushing's syndrome, acute psychosis, aminoglutethimide therapy.
    Proceedings of the Royal Society of Medicine, 1970, Volume: 63, Issue:4

    Topics: Adrenalectomy; Adult; Aminoglutethimide; Aniline Compounds; Anticonvulsants; Cushing Syndrome; Femal

1970
Evidence suggesting 11 beta-hydroxylase inhibition during aminoglutethimide administration.
    Metabolism: clinical and experimental, 1971, Volume: 20, Issue:3

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Glands; Aminoglutethimide; Aniline Compounds; An

1971
[Corticosteroidogenesis inhibitors. II. A new cortico-adrenal inhibitor: amino-glutethimide (16,038Ba)].
    La Presse medicale, 1968, May-11, Volume: 76, Issue:23

    Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal G

1968
[Inhibitions of steroid biosynthesis in the adrenal gland by aminogluthetimide (Elipten CIBA) and its practical significance].
    Vnitrni lekarstvi, 1969, Volume: 15, Issue:5

    Topics: 17-Ketosteroids; Adrenal Glands; Aminoglutethimide; Aniline Compounds; Anticonvulsants; Cushing Synd

1969
Amino-glutethimide and metastatic adrenal cancer. Maintained reversal (six months) of Cushing's syndrome.
    JAMA, 1966, Nov-28, Volume: 198, Issue:9

    Topics: Adrenal Gland Neoplasms; Adult; Aminoglutethimide; Anticonvulsants; Antineoplastic Agents; Carbon Is

1966