Page last updated: 2024-10-22

aminoglutethimide and Choriocarcinoma

aminoglutethimide has been researched along with Choriocarcinoma in 3 studies

Aminoglutethimide: An aromatase inhibitor that is used in the treatment of advanced BREAST CANCER.
aminoglutethimide : A dicarboximide that is a six-membered cyclic compound having ethyl and 4-aminophenyl substituents at the 3-position.

Choriocarcinoma: A malignant metastatic form of trophoblastic tumors. Unlike the HYDATIDIFORM MOLE, choriocarcinoma contains no CHORIONIC VILLI but rather sheets of undifferentiated cytotrophoblasts and syncytiotrophoblasts (TROPHOBLASTS). It is characterized by the large amounts of CHORIONIC GONADOTROPIN produced. Tissue origins can be determined by DNA analyses: placental (fetal) origin or non-placental origin (CHORIOCARCINOMA, NON-GESTATIONAL).

Research Excerpts

ExcerptRelevanceReference
" Additionally, compound 2 inhibited androstenedione-induced uterine hypertrophy in sexually immature mice (41% of uterine weight suppression for compound 2 versus 51% for AG)."3.71Aromatase inhibition by an 11,13-dihydroderivative of a sesquiterpene lactone. ( Blanco, JG; Bocco, JL; Flury, A; Genti-Raimondi, S; Gil, RR; Meragelman, TL, 2001)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Simpson, ER1
Burkhart, MF1
Blanco, JG1
Gil, RR1
Bocco, JL1
Meragelman, TL1
Genti-Raimondi, S1
Flury, A1
Soudon, J1

Other Studies

3 other studies available for aminoglutethimide and Choriocarcinoma

ArticleYear
Regulation of cholesterol metabolism by human choriocarcinoma cells in culture: effect of lipoproteins and progesterone on cholesteryl ester synthesis.
    Archives of biochemistry and biophysics, 1980, Volume: 200, Issue:1

    Topics: Aminoglutethimide; Cells, Cultured; Chloroquine; Cholesterol; Cholesterol Esters; Choriocarcinoma; F

1980
Aromatase inhibition by an 11,13-dihydroderivative of a sesquiterpene lactone.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 297, Issue:3

    Topics: Aminoglutethimide; Androstenedione; Animals; Antineoplastic Agents; Aromatase; Aromatase Inhibitors;

2001
Comparison of in vitro exemestane activity versus other antiaromatase agents.
    Clinical breast cancer, 2000, Volume: 1 Suppl 1

    Topics: Aminoglutethimide; Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Choriocarcin

2000