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aminoglutethimide and Cardiomegaly

aminoglutethimide has been researched along with Cardiomegaly in 1 studies

Aminoglutethimide: An aromatase inhibitor that is used in the treatment of advanced BREAST CANCER.
aminoglutethimide : A dicarboximide that is a six-membered cyclic compound having ethyl and 4-aminophenyl substituents at the 3-position.

Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.

Research Excerpts

ExcerptRelevanceReference
"With reference to the indirect evidence showing that heart growth in the presence of a cardiac overload is modulated by the adrenal cortex, we studied heart reactions to overloading (ligation of the abdominal aorta or hyperthyroidism) with simultaneous administration of aminoglutethimide, an inhibitor of steroidogenesis."7.66Aminoglutethimide, an inhibitor of adrenal steroidogenesis, blocks heart growth after ligation of the abdominal aorta and in hyperthyroidism in rats. ( Jahodová, J; Kölbel, F; Kubová, V; Pribyl, T; Schreiber, V, 1982)
"With reference to the indirect evidence showing that heart growth in the presence of a cardiac overload is modulated by the adrenal cortex, we studied heart reactions to overloading (ligation of the abdominal aorta or hyperthyroidism) with simultaneous administration of aminoglutethimide, an inhibitor of steroidogenesis."3.66Aminoglutethimide, an inhibitor of adrenal steroidogenesis, blocks heart growth after ligation of the abdominal aorta and in hyperthyroidism in rats. ( Jahodová, J; Kölbel, F; Kubová, V; Pribyl, T; Schreiber, V, 1982)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schreiber, V1
Kölbel, F1
Pribyl, T1
Jahodová, J1
Kubová, V1

Other Studies

1 other study available for aminoglutethimide and Cardiomegaly

ArticleYear
Aminoglutethimide, an inhibitor of adrenal steroidogenesis, blocks heart growth after ligation of the abdominal aorta and in hyperthyroidism in rats.
    Physiologia Bohemoslovaca, 1982, Volume: 31, Issue:6

    Topics: Aminoglutethimide; Animals; Aorta, Abdominal; Cardiomegaly; Heart; Hyperthyroidism; Male; Methylthio

1982