aminoglutethimide has been researched along with Cardiomegaly in 1 studies
Aminoglutethimide: An aromatase inhibitor that is used in the treatment of advanced BREAST CANCER.
aminoglutethimide : A dicarboximide that is a six-membered cyclic compound having ethyl and 4-aminophenyl substituents at the 3-position.
Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "With reference to the indirect evidence showing that heart growth in the presence of a cardiac overload is modulated by the adrenal cortex, we studied heart reactions to overloading (ligation of the abdominal aorta or hyperthyroidism) with simultaneous administration of aminoglutethimide, an inhibitor of steroidogenesis." | 7.66 | Aminoglutethimide, an inhibitor of adrenal steroidogenesis, blocks heart growth after ligation of the abdominal aorta and in hyperthyroidism in rats. ( Jahodová, J; Kölbel, F; Kubová, V; Pribyl, T; Schreiber, V, 1982) |
| "With reference to the indirect evidence showing that heart growth in the presence of a cardiac overload is modulated by the adrenal cortex, we studied heart reactions to overloading (ligation of the abdominal aorta or hyperthyroidism) with simultaneous administration of aminoglutethimide, an inhibitor of steroidogenesis." | 3.66 | Aminoglutethimide, an inhibitor of adrenal steroidogenesis, blocks heart growth after ligation of the abdominal aorta and in hyperthyroidism in rats. ( Jahodová, J; Kölbel, F; Kubová, V; Pribyl, T; Schreiber, V, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schreiber, V | 1 |
| Kölbel, F | 1 |
| Pribyl, T | 1 |
| Jahodová, J | 1 |
| Kubová, V | 1 |
1 other study available for aminoglutethimide and Cardiomegaly
| Article | Year |
|---|---|
Aminoglutethimide, an inhibitor of adrenal steroidogenesis, blocks heart growth after ligation of the abdominal aorta and in hyperthyroidism in rats.
Topics: Aminoglutethimide; Animals; Aorta, Abdominal; Cardiomegaly; Heart; Hyperthyroidism; Male; Methylthio | 1982 |