aminoglutethimide has been researched along with Cardiac Hypertrophy in 1 studies
Aminoglutethimide: An aromatase inhibitor that is used in the treatment of advanced BREAST CANCER.
aminoglutethimide : A dicarboximide that is a six-membered cyclic compound having ethyl and 4-aminophenyl substituents at the 3-position.
Cardiac Hypertrophy: Enlargement of the HEART due to chamber HYPERTROPHY, an increase in wall thickness without an increase in the number of cells (MYOCYTES, CARDIAC). It is the result of increase in myocyte size, mitochondrial and myofibrillar mass, as well as changes in extracellular matrix.
| Excerpt | Relevance | Reference |
|---|---|---|
| "With reference to the indirect evidence showing that heart growth in the presence of a cardiac overload is modulated by the adrenal cortex, we studied heart reactions to overloading (ligation of the abdominal aorta or hyperthyroidism) with simultaneous administration of aminoglutethimide, an inhibitor of steroidogenesis." | 7.66 | Aminoglutethimide, an inhibitor of adrenal steroidogenesis, blocks heart growth after ligation of the abdominal aorta and in hyperthyroidism in rats. ( Jahodová, J; Kölbel, F; Kubová, V; Pribyl, T; Schreiber, V, 1982) |
| "With reference to the indirect evidence showing that heart growth in the presence of a cardiac overload is modulated by the adrenal cortex, we studied heart reactions to overloading (ligation of the abdominal aorta or hyperthyroidism) with simultaneous administration of aminoglutethimide, an inhibitor of steroidogenesis." | 3.66 | Aminoglutethimide, an inhibitor of adrenal steroidogenesis, blocks heart growth after ligation of the abdominal aorta and in hyperthyroidism in rats. ( Jahodová, J; Kölbel, F; Kubová, V; Pribyl, T; Schreiber, V, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schreiber, V | 1 |
| Kölbel, F | 1 |
| Pribyl, T | 1 |
| Jahodová, J | 1 |
| Kubová, V | 1 |
1 other study available for aminoglutethimide and Cardiac Hypertrophy
| Article | Year |
|---|---|
Aminoglutethimide, an inhibitor of adrenal steroidogenesis, blocks heart growth after ligation of the abdominal aorta and in hyperthyroidism in rats.
Topics: Aminoglutethimide; Animals; Aorta, Abdominal; Cardiomegaly; Heart; Hyperthyroidism; Male; Methylthio | 1982 |