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aminoglutethimide and Cancer of Prostate

aminoglutethimide has been researched along with Cancer of Prostate in 64 studies

Aminoglutethimide: An aromatase inhibitor that is used in the treatment of advanced BREAST CANCER.
aminoglutethimide : A dicarboximide that is a six-membered cyclic compound having ethyl and 4-aminophenyl substituents at the 3-position.

Research Excerpts

ExcerptRelevanceReference
"Clinical and biochemical evidence of hypothyroidism (thyrotropin levels greater than 10 mU/L) was noted in nine of 29 patients treated following the initiation of aminoglutethimide (250 mg four times daily)."7.69Hypothyroidism associated with aminoglutethimide in patients with prostate cancer. ( Calis, KA; Cooper, MR; Figg, WD; Headlee, D; Mays, D; Sartor, AO; Thibault, A, 1994)
"Clinical and biochemical evidence of hypothyroidism (thyrotropin levels greater than 10 mU/L) was noted in nine of 29 patients treated following the initiation of aminoglutethimide (250 mg four times daily)."3.69Hypothyroidism associated with aminoglutethimide in patients with prostate cancer. ( Calis, KA; Cooper, MR; Figg, WD; Headlee, D; Mays, D; Sartor, AO; Thibault, A, 1994)
"Forty patients with metastatic adenocarcinoma of the prostate were evaluated for response to treatment with aminoglutethimide plus cortisone acetate."3.67Response to aminoglutethimide and cortisone acetate in advanced prostatic cancer. ( Chilvers, CE; Dowsett, M; Easton, D; Jeffcoate, SL; Miller, J; Pocock, RD; Ponder, BA; Shearer, RJ, 1984)
"Marked leukopenia and/or thrombocytopenia occurred in 12 of 1333 patients treated with aminoglutethimide (0."3.67Aminoglutethimide-induced hematologic toxicity: worldwide experience. ( Boucher, AE; Buzdar, AU; Harvey, HA; Henderson, IC; Lipton, A; Messeih, AA; Murray, R; Nagel, GA; Ragaz, J; Santen, RJ, 1985)
"Management of prostate cancer progression after failure of initial hormonal therapy is controversial."2.69Phase II study of suramin plus aminoglutethimide in two cohorts of patients with androgen-independent prostate cancer: simultaneous antiandrogen withdrawal and prior antiandrogen withdrawal. ( Bergan, R; Brawley, OW; Cooper, MR; Dawson, N; Figg, WD; Headlee, D; Linehan, WM; Patronas, N; Reed, E; Sartor, O; Sausville, E; Senderowicz, A; Steinberg, SM; Sutherland, M, 1998)
"A total of 59 patients with advanced prostate cancer relapsed from or refractory to castration plus oestrogen were treated in a randomised trial comparing 1000 to 1250 mg aminoglutethimide + 40 mg hydrocortisone (AG + HC) with 500 mg medroxyprogesterone acetate + 40 mg hydrocortisone (MPA + HC)."2.67Treatment of stage D2 prostatic cancer refractory to or relapsed following castration plus oestrogens. Comparison of aminoglutethimide plus hydrocortisone with medroxyprogesterone acetate plus hydrocortisone. ( Bezwoda, WR, 1990)
"Eighty-five men with progressive prostate cancer refractory to orchiectomy were treated continuously with aminoglutethimide and hydrocortisone to lower adrenal androgen secretion and were administered cyclic intravenous (IV) chemotherapy."2.66Androgen priming and chemotherapy in advanced prostate cancer: evaluation of determinants of clinical outcome. ( Bartholomew, M; Boucher, A; Caplan, R; Gordon, R; Harvey, H; Lipton, A; Manni, A; Santen, R; Simmonds, M; White-Hershey, D, 1988)
"Seventy-five patients with stage D-2 prostate cancer refractory to orchiectomy have been entered in a controlled trial to test whether androgen priming enhances the efficacy of chemotherapy."2.66Androgen depletion and repletion as a means of potentiating the effect of cytotoxic chemotherapy in advanced prostate cancer. ( Boucher, AE; Drago, J; Gordon, R; Harvey, H; Lipton, A; Manni, A; Rohner, T; Santen, RJ; Simmonds, M; Wettlaufer, J, 1987)
"The term "hormone-refractory" prostate cancer has evolved to include patients with a spectrum of diseases."2.39Hormone-refractory (D3) prostate cancer: refining the concept. ( Kelly, WK; Scher, HI; Steineck, G, 1995)
"Almost all patients with prostatic cancer will eventually escape the control of the first-line endocrine therapy and relapse."2.38Management of relapsing disease in prostate cancer. ( Denis, L; Mahler, C, 1992)
"About one third of patients with breast cancer show objective improvement with aminoglutethimide, and it may also be of use in the treatment of adrenal carcinoma."2.37Aminoglutethimide and ketoconazole: historical perspectives and future prospects. ( Nicholls, PJ; Shaw, MA; Smith, HJ, 1988)
"Flutamide withdrawal, when combined with the simultaneous administration of aminoglutethimide, is a therapeutically active approach in patients with "hormone-refractory" prostate cancer."1.29Surprising activity of flutamide withdrawal, when combined with aminoglutethimide, in treatment of "hormone-refractory" prostate cancer. ( Cooper, M; Figg, WD; Headlee, D; Linehan, WM; Myers, CE; Sartor, O; Steinberg, S; Thibault, A; Tompkins, A; Weinberger, M, 1994)
"Sections of benign prostatic hyperplasia and prostatic carcinoma from each patient were stained with antibodies to AR and GR using an avidin-biotin peroxidase technique."1.29Androgen and glucocorticoid receptors in the stroma and epithelium of prostatic hyperplasia and carcinoma. ( Chen, Y; Cidlowski, JA; French, FS; Hall, SH; Hamil, K; Mohler, JL; Sar, M; Wilson, EM, 1996)
"Ten castrated patients with prostatic cancer received flutamide (FLU) alone for 2 months and, afterwards, the combined therapy of FLU and AG for 2 months."1.27Effects of flutamide and aminoglutethimide on plasma 5 alpha-reduced steroid glucuronide concentrations in castrated patients with cancer of the prostate. ( Bélanger, A; Brochu, M; Cusan, L; Dupont, A; Labrie, F, 1987)
"Aminoglutethimide has been used in combination with hydrocortisone in patients with advanced prostatic cancer with the rationale that it causes a 'medical adrenalectomy'."1.27The effects of aminoglutethimide and hydrocortisone, alone and combined, on androgen levels in post-orchiectomy prostatic cancer patients. ( Dowsett, M; Jeffcoate, SL; Malone, P; Ponder, BA; Shearer, RJ, 1988)
"Aminoglutethimide (AG) is a drug that inhibits several steps of steroidogenesis; it is used in post-menopausal advanced breast cancer."1.27[Aminoglutethimide and cancer of the prostate]. ( Bonneterre, J, 1986)
" Drug intervention should be on a regular schedule--avoid prn dosage of pain medications."1.27Dilemmas in managing prostate carcinoma (Part II): Metastatic disease. ( Ahmann, FR, 1985)

Research

Studies (64)

TimeframeStudies, this research(%)All Research%
pre-199048 (75.00)18.7374
1990's14 (21.88)18.2507
2000's2 (3.13)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kruit, WH1
Stoter, G1
Klijn, JG1
Hobdy, EM1
Shafi, NQ1
Kummar, S1
Jacobi, GH1
Wenderoth, UK1
Ponder, BA2
Shearer, RJ4
Pocock, RD1
Miller, J1
Easton, D1
Chilvers, CE1
Dowsett, M2
Jeffcoate, SL2
Soloway, MS1
Drago, JR3
Santen, RJ5
Lipton, A7
Worgul, TJ2
Harvey, HA3
Boucher, A2
Manni, A4
Rohner, TJ4
Block, M1
Trump, D1
Rose, DP1
Cummings, KB1
Hogan, TF1
Samojlik, E2
Veldhuis, JD1
Rostom, AY1
Folkes, A1
Lord, C1
Notley, RG1
Schweitzer, FA1
White, WF1
Shessel, FS1
Block, NL1
Stover, B1
Claflin, A1
Malinin, TI1
Politano, VA1
Robinson, MR3
Sartor, O3
Cooper, M1
Weinberger, M1
Headlee, D3
Thibault, A2
Tompkins, A2
Steinberg, S1
Figg, WD4
Linehan, WM2
Myers, CE1
Scher, HI2
Steineck, G1
Kelly, WK2
Sartor, AO1
Mays, D1
Calis, KA1
Cooper, MR2
Zhang, ZF1
Nanus, D1
Dawson, N2
Middleman, MN1
Brawley, O1
Lush, RM1
Senderowicz, A2
Steinberg, SH1
Reed, E2
Brawley, OW1
Bergan, R1
Steinberg, SM1
Sutherland, M1
Patronas, N1
Sausville, E1
Bare, RL1
Torti, FM1
Mohler, JL1
Chen, Y1
Hamil, K1
Hall, SH1
Cidlowski, JA1
Wilson, EM1
French, FS1
Sar, M1
Sanford, EJ1
Santen, R2
Mahler, C1
Denis, L1
Dik, P1
Blom, JH1
Schröder, FH1
Abe, K1
Adshead, F1
De Graeff, A1
Mansi, JL1
Thomas, DM1
Smith, IE1
McConnell, JD1
Bezwoda, WR1
Chang, AY1
Bennett, JM1
Pandya, KJ1
Asbury, R1
McCune, C1
Vachalovský, V2
Vomácka, V2
Van Wauwe, JP1
Janssen, PA1
Labrie, F2
Dupont, A2
Bélanger, A2
Cusan, L2
Brochu, M2
Turina, E1
Pinault, S1
Lacourciere, Y1
Emond, J1
Knönagel, H1
Hauri, D1
Havlin, KA1
Trump, DL1
Geller, J1
Albert, JD1
Sogani, PC1
Fair, WR1
Shaw, MA1
Nicholls, PJ1
Smith, HJ1
Bartholomew, M1
Caplan, R1
Harvey, H3
Simmonds, M3
White-Hershey, D2
Gordon, R2
Lippman, AJ1
Kirschner, MA1
Ertel, NH1
Park, Y1
Szmal, E1
Malone, P1
Elomaa, I1
Taube, T1
Blomqvist, C1
Rissanen, P1
Rannikko, S1
Alfthan, O1
Melamed, AJ1
Boucher, AE3
Gordon, RA1
Drago, J2
Harnett, PR1
Raghavan, D1
Caterson, I1
Pearson, B1
Watt, H1
Teriana, N1
Coates, A1
Coorey, G1
Nicholson, RI1
Walker, KJ1
Davies, P1
Plowman, PN1
Perry, LA1
Chard, T1
Ahmann, FR3
Crawford, ED2
Kreis, W1
Levasseur, Y1
Murray, R3
Pitt, P2
Davis, MA1
Levasseur, YJ1
Rohner, T1
Wettlaufer, J1
Bonneterre, J1
Box, M1
Saltissi, D1
Fawcett, D1
Schroeder, FH1
Dubost, JJ1
Sauvezie, B1
Ristori, JM1
Thevenet, JP1
Rampon, S1
Messeih, AA1
Ragaz, J1
Buzdar, AU1
Nagel, GA1
Henderson, IC1
Blankenstein, MA1
Bakker, GH1
Bauer, HW1
Schmeller, NT1
Schmiedt, E1
Hendry, WF1
Sommerville, IF1
Fergusson, JD2
Morales, A2
Thomas, BS1
Connolly, JG1
Mobbs, BG1
Kraus, A1

Reviews

17 reviews available for aminoglutethimide and Cancer of Prostate

ArticleYear
Effect of combination therapy with aminoglutethimide and hydrocortisone on prostate-specific antigen response in metastatic prostate cancer refractory to standard endocrine therapy.
    Anti-cancer drugs, 2004, Volume: 15, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Aminoglutethimide; Antineoplastic Agents, Hormonal; Antineoplastic C

2004
New forms and future perspectives in endocrine treatment of prostatic carcinoma.
    Progress in clinical and biological research, 1984, Volume: 153

    Topics: Aminoglutethimide; Androgen Antagonists; Cyproterone; Cyproterone Acetate; Estrogen Antagonists; Flu

1984
Hormone-refractory (D3) prostate cancer: refining the concept.
    Urology, 1995, Volume: 46, Issue:2

    Topics: Aminoglutethimide; Clinical Trials as Topic; Cortisone; Dexamethasone; Drug Therapy, Combination; Hu

1995
Hormone and antihormone withdrawal: implications for the management of androgen-independent prostate cancer.
    Urology, 1996, Volume: 47, Issue:1A Suppl

    Topics: Aminoglutethimide; Androgen Antagonists; Clinical Trials as Topic; Flutamide; Humans; Male; Neoplasm

1996
Endocrine therapy of prostate cancer.
    Cancer treatment and research, 1998, Volume: 94

    Topics: 5-alpha Reductase Inhibitors; Adenocarcinoma; Aminoglutethimide; Androgen Antagonists; Antineoplasti

1998
Aminoglutethimide medical adrenalectomy for advanced prostatic carcinoma.
    The Journal of urology, 1976, Volume: 115, Issue:2

    Topics: Adenocarcinoma; Adrenal Glands; Aged; Aminoglutethimide; Female; Humans; Male; Prostatic Neoplasms

1976
Management of relapsing disease in prostate cancer.
    Cancer, 1992, Jul-01, Volume: 70, Issue:1 Suppl

    Topics: Aminoglutethimide; Androgen Antagonists; Antineoplastic Agents; Combined Modality Therapy; Estrogens

1992
[Hormone therapy of neoplasms].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1991, Mar-10, Volume: 80, Issue:3

    Topics: Adenoma, Islet Cell; Aminoglutethimide; Breast Neoplasms; Female; Fluoxymesterone; Humans; Male; Med

1991
Physiologic basis of endocrine therapy for prostatic cancer.
    The Urologic clinics of North America, 1991, Volume: 18, Issue:1

    Topics: Aminoglutethimide; Androgen Antagonists; Androgens; Estrogens; Gonadotropin-Releasing Hormone; Human

1991
Is there a case for P-450 inhibitors in cancer treatment?
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:10

    Topics: Aminoglutethimide; Aromatase Inhibitors; Breast Neoplasms; Cytochrome P-450 Enzyme Inhibitors; Enzym

1989
Aminoglutethimide: theoretical considerations and clinical results in advanced prostate cancer.
    Cancer treatment and research, 1988, Volume: 39

    Topics: Adrenal Glands; Aminoglutethimide; Androgens; Humans; Male; Prostatic Neoplasms

1988
Adrenal androgen blockade in relapsed prostate cancer.
    European journal of cancer & clinical oncology, 1985, Volume: 21, Issue:10

    Topics: Adrenalectomy; Aminoglutethimide; Androgen Antagonists; Castration; Combined Modality Therapy; Cypro

1985
Treatment of advanced prostatic cancer.
    The Urologic clinics of North America, 1987, Volume: 14, Issue:2

    Topics: Adrenalectomy; Aminoglutethimide; Androgen Antagonists; Antineoplastic Combined Chemotherapy Protoco

1987
Aminoglutethimide and ketoconazole: historical perspectives and future prospects.
    Journal of steroid biochemistry, 1988, Volume: 31, Issue:1

    Topics: Adrenal Gland Neoplasms; Aminoglutethimide; Aromatase Inhibitors; Breast Neoplasms; Fadrozole; Femal

1988
Hormone agonists and antagonists in the treatment of hormone sensitive breast and prostate cancer.
    Cancer surveys, 1986, Volume: 5, Issue:3

    Topics: Aminoglutethimide; Androgen Antagonists; Breast Neoplasms; Estrogen Antagonists; Female; Gonadotropi

1986
Total androgen suppression in the management of prostatic cancer. A critical review.
    Progress in clinical and biological research, 1985, Volume: 185A

    Topics: Adrenalectomy; Aminoglutethimide; Androgen Antagonists; Castration; Diethylstilbestrol; Dihydrotesto

1985
[New hormonal treatments of metastatic prostatic cancer. Review of the literature].
    Revue du rhumatisme et des maladies osteo-articulaires, 1985, Volume: 52, Issue:10

    Topics: Aminoglutethimide; Androgen Antagonists; Animals; Antineoplastic Agents; Combined Modality Therapy;

1985

Trials

10 trials available for aminoglutethimide and Cancer of Prostate

ArticleYear
Effect of combination therapy with aminoglutethimide and hydrocortisone on prostate-specific antigen response in metastatic prostate cancer refractory to standard endocrine therapy.
    Anti-cancer drugs, 2004, Volume: 15, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Aminoglutethimide; Antineoplastic Agents, Hormonal; Antineoplastic C

2004
Phase II study of suramin plus aminoglutethimide in two cohorts of patients with androgen-independent prostate cancer: simultaneous antiandrogen withdrawal and prior antiandrogen withdrawal.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1998, Volume: 4, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aminoglutethimide; Androgen Antagonists; Antineoplastic Combined Che

1998
Mitomycin C and aminoglutethimide in the treatment of metastatic prostatic cancer: a phase II study.
    British journal of urology, 1992, Volume: 70, Issue:5

    Topics: Aged; Aged, 80 and over; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Humans;

1992
Treatment of stage D2 prostatic cancer refractory to or relapsed following castration plus oestrogens. Comparison of aminoglutethimide plus hydrocortisone with medroxyprogesterone acetate plus hydrocortisone.
    British journal of urology, 1990, Volume: 66, Issue:2

    Topics: Aged; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Combined Mo

1990
[Orimeten in the treatment of advanced carcinoma of the prostate].
    Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti, 1989, Volume: 68, Issue:4

    Topics: Aged; Aged, 80 and over; Aminoglutethimide; Antineoplastic Agents; Carcinoma; Cyclophosphamide; Drug

1989
Treatment of advanced prostatic cancer.
    The Urologic clinics of North America, 1987, Volume: 14, Issue:2

    Topics: Adrenalectomy; Aminoglutethimide; Androgen Antagonists; Antineoplastic Combined Chemotherapy Protoco

1987
Androgen priming and chemotherapy in advanced prostate cancer: evaluation of determinants of clinical outcome.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1988, Volume: 6, Issue:9

    Topics: Acid Phosphatase; Aged; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Clinical

1988
Androgen priming and response to chemotherapy in advanced prostatic cancer.
    The Journal of urology, 1986, Volume: 136, Issue:6

    Topics: Aged; Aged, 80 and over; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Clinical

1986
Aminoglutethimide in advanced prostatic carcinoma.
    British journal of urology, 1987, Volume: 59, Issue:4

    Topics: Aged; Aminoglutethimide; Clinical Trials as Topic; Diethylstilbestrol; Drug Therapy, Combination; Hu

1987
Androgen depletion and repletion as a means of potentiating the effect of cytotoxic chemotherapy in advanced prostate cancer.
    Journal of steroid biochemistry, 1987, Volume: 27, Issue:1-3

    Topics: Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Combined Modality

1987

Other Studies

39 other studies available for aminoglutethimide and Cancer of Prostate

ArticleYear
Prostate cancer metastasis to supraclavicular lymph node.
    Clinical advances in hematology & oncology : H&O, 2004, Volume: 2, Issue:4

    Topics: Acid Phosphatase; Adenocarcinoma; Aged; Aminoglutethimide; Antineoplastic Combined Chemotherapy Prot

2004
Response to aminoglutethimide and cortisone acetate in advanced prostatic cancer.
    British journal of cancer, 1984, Volume: 50, Issue:6

    Topics: Adenocarcinoma; Aged; Aminoglutethimide; Androstenedione; Antineoplastic Combined Chemotherapy Proto

1984
Newer methods of hormonal therapy for prostate cancer.
    Urology, 1984, Volume: 24, Issue:5 Suppl

    Topics: Adenocarcinoma; Aminoglutethimide; Androgen Antagonists; Bone Neoplasms; Buserelin; Flutamide; Gonad

1984
Clinical effect of aminoglutethimide, medical adrenalectomy, in treatment of 43 patients with advanced prostatic carcinoma.
    Cancer, 1984, Apr-01, Volume: 53, Issue:7

    Topics: Adenocarcinoma; Adrenalectomy; Aged; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protoco

1984
Evaluation of aminoglutethimide in stage D prostate cancer: an assessment of efficacy and toxicity in patients with tumors refractory to hormonal therapy.
    Cancer treatment reports, 1984, Volume: 68, Issue:5

    Topics: Aminoglutethimide; Antineoplastic Agents; Aspartate Aminotransferases; Drug Evaluation; Electrolytes

1984
Clinical and biochemical effect of aminoglutethimide in the treatment of advanced prostatic carcinoma.
    The Journal of urology, 1983, Volume: 129, Issue:1

    Topics: Adenocarcinoma; Aged; Aminoglutethimide; Bone Neoplasms; Dihydrotestosterone; Drug Therapy, Combinat

1983
Aminoglutethimide therapy for advanced carcinoma of the prostate.
    British journal of urology, 1982, Volume: 54, Issue:5

    Topics: Aged; Aminoglutethimide; Analgesics; Humans; Male; Middle Aged; Prostatic Neoplasms

1982
Endocrine manipulation of the Dunning prostatic adenocarcinoma.
    Investigative urology, 1980, Volume: 17, Issue:6

    Topics: Adenocarcinoma; Adrenalectomy; Aminoglutethimide; Animals; Castration; Diethylstilbestrol; Disease M

1980
Aminoglutethimide: medical adrenalectomy in the management of carcinoma of the prostate. A review after 6 years.
    British journal of urology, 1980, Volume: 52, Issue:4

    Topics: Adrenal Glands; Aminoglutethimide; Drug Evaluation; Follow-Up Studies; Humans; Male; Prostatic Neopl

1980
Surprising activity of flutamide withdrawal, when combined with aminoglutethimide, in treatment of "hormone-refractory" prostate cancer.
    Journal of the National Cancer Institute, 1994, Feb-02, Volume: 86, Issue:3

    Topics: Aged; Aged, 80 and over; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Flutamid

1994
Hypothyroidism associated with aminoglutethimide in patients with prostate cancer.
    Archives of internal medicine, 1994, May-09, Volume: 154, Issue:9

    Topics: Aged; Aminoglutethimide; Diagnosis, Differential; Humans; Hypothyroidism; Male; Prospective Studies;

1994
Flutamide withdrawal and concomitant initiation of aminoglutethimide in patients with hormone refractory prostate cancer.
    Acta oncologica (Stockholm, Sweden), 1996, Volume: 35, Issue:6

    Topics: Aged; Aminoglutethimide; Androgen Antagonists; Antineoplastic Agents, Hormonal; Drug Resistance, Neo

1996
Androgen and glucocorticoid receptors in the stroma and epithelium of prostatic hyperplasia and carcinoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1996, Volume: 2, Issue:5

    Topics: Aged; Aminoglutethimide; Epithelial Cells; Humans; Immunohistochemistry; Ketoconazole; Male; Middle

1996
Small cell carcinoma of the prostate: implications for management.
    British journal of urology, 1991, Volume: 67, Issue:2

    Topics: Adenocarcinoma; Aminoglutethimide; Bone Neoplasms; Carcinoma, Small Cell; Cyclophosphamide; Doxorubi

1991
A study of aminoglutethemide and hydrocortisone in patients with advanced and refractory prostate carcinoma.
    American journal of clinical oncology, 1989, Volume: 12, Issue:4

    Topics: Aminoglutethimide; Carcinoma; Drug Evaluation; Drug Therapy, Combination; Humans; Hydrocortisone; Ma

1989
Anti-hormone treatment for prostate cancer relapsing after treatment with flutamide and castration. Addition of aminoglutethimide and low dose hydrocortisone to combination therapy.
    British journal of urology, 1989, Volume: 63, Issue:6

    Topics: Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Flutam

1989
[The effect of aminoglutethimide on steroid synthesis of the adrenal gland and its use in prostate cancer].
    Helvetica chirurgica acta, 1989, Volume: 56, Issue:3

    Topics: Adrenal Cortex; Aged; Aged, 80 and over; Aminoglutethimide; Androgens; Combined Modality Therapy; Hu

1989
Effects of flutamide and aminoglutethimide on plasma 5 alpha-reduced steroid glucuronide concentrations in castrated patients with cancer of the prostate.
    Journal of steroid biochemistry, 1987, Volume: 28, Issue:6

    Topics: Aged; Aminoglutethimide; Androstane-3,17-diol; Androstanols; Androsterone; Anilides; Dehydroepiandro

1987
Medical adrenalectomy for advanced prostatic cancer: clinical and hormonal effects.
    American journal of clinical oncology, 1988, Volume: 11, Issue:5

    Topics: Aged; Aged, 80 and over; Aminoglutethimide; Androgens; Antineoplastic Combined Chemotherapy Protocol

1988
[Orimeten in the treatment of advanced prostatic carcinoma].
    Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti, 1988, Volume: 67, Issue:10

    Topics: Aged; Aged, 80 and over; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Carcinom

1988
The effects of aminoglutethimide and hydrocortisone, alone and combined, on androgen levels in post-orchiectomy prostatic cancer patients.
    British journal of cancer, 1988, Volume: 57, Issue:2

    Topics: Aged; Aged, 80 and over; Aminoglutethimide; Androstenedione; Antineoplastic Combined Chemotherapy Pr

1988
Aminoglutethimide for advanced prostatic cancer resistant to conventional hormonal therapy.
    European urology, 1988, Volume: 14, Issue:2

    Topics: Aged; Aged, 80 and over; Aminoglutethimide; Bone Neoplasms; Drug Therapy, Combination; Humans; Hydro

1988
Correction: prostate cancer treatment.
    Drug intelligence & clinical pharmacy, 1987, Volume: 21, Issue:10

    Topics: Aminoglutethimide; Humans; Male; Prostatic Neoplasms

1987
Androgen suppression by hydrocortisone without aminoglutethimide in orchiectomised men with prostatic cancer.
    British journal of urology, 1987, Volume: 59, Issue:3

    Topics: Aged; Aged, 80 and over; Aminoglutethimide; Androgen Antagonists; Androgens; Drug Therapy, Combinati

1987
Adrenal steroid levels in castrated men with prostatic carcinoma treated with aminoglutethimide plus hydrocortisone.
    Cancer research, 1987, Sep-01, Volume: 47, Issue:17

    Topics: Aminoglutethimide; Androgens; Androstenedione; Drug Therapy, Combination; Humans; Hydrocortisone; Ma

1987
Aminoglutethimide in the treatment of advanced prostatic cancer.
    Progress in clinical and biological research, 1987, Volume: 243A

    Topics: Aged; Aged, 80 and over; Aminoglutethimide; Humans; Male; Middle Aged; Orchiectomy; Prostatic Neopla

1987
Aminoglutethimide in metastatic adenocarcinoma of the prostate.
    Progress in clinical and biological research, 1987, Volume: 243A

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Aminoglutethimide; Humans; Hydrocortisone; Male; Mid

1987
[Aminoglutethimide and cancer of the prostate].
    Bulletin du cancer, 1986, Volume: 73, Issue:1

    Topics: Adrenal Glands; Aminoglutethimide; Androgens; Drug Evaluation; Humans; Male; Prostatic Neoplasms

1986
Inappropriate secretion of antidiuretic hormone following aminoglutethimide therapy.
    British journal of urology, 1986, Volume: 58, Issue:6

    Topics: Aged; Aminoglutethimide; Humans; Inappropriate ADH Syndrome; Male; Prostatic Neoplasms

1986
Dilemmas in managing prostate carcinoma (Part II): Metastatic disease.
    Geriatrics, 1985, Volume: 40, Issue:9

    Topics: Aged; Aminoglutethimide; Aspirin; Bone Neoplasms; Castration; Diethylstilbestrol; Disseminated Intra

1985
Treatment of advanced prostatic cancer, resistant to conventional therapy, with aminoglutethimide.
    European journal of cancer & clinical oncology, 1985, Volume: 21, Issue:4

    Topics: Aged; Aminoglutethimide; Castration; Combined Modality Therapy; Estrogens; Follow-Up Studies; Humans

1985
Aminoglutethimide-induced hematologic toxicity: worldwide experience.
    Cancer treatment reports, 1985, Volume: 69, Issue:9

    Topics: Aminoglutethimide; Blood Cell Count; Breast Neoplasms; Female; Global Health; Hematologic Diseases;

1985
Rationale for suppression of adrenal steroidogenesis in advanced prostatic cancer.
    Progress in clinical and biological research, 1985, Volume: 185A

    Topics: Adrenal Cortex Hormones; Aminoglutethimide; Androgen Antagonists; Androgens; Animals; Estrogens; Hum

1985
[Aminoglutethimide in the treatment of advanced prostatic cancer].
    Der Urologe. Ausg. A, 1985, Volume: 24, Issue:1

    Topics: Acid Phosphatase; Aged; Aminoglutethimide; Castration; Combined Modality Therapy; Estradiol; Estradi

1985
Plasma testosterone: an accurate monitor of hormone treatment in prostatic cancer.
    British journal of urology, 1973, Volume: 45, Issue:6

    Topics: Adrenal Glands; Aminoglutethimide; Castration; Circadian Rhythm; Diethylstilbestrol; Estrogens; Estr

1973
Adrenal suppression in the treatment of carcinoma of the prostate.
    British journal of urology, 1974, Volume: 46, Issue:5

    Topics: Acid Phosphatase; Administration, Oral; Adrenal Glands; Aged; Alkaline Phosphatase; Aminoglutethimid

1974
Steroid biosynthesis and lymphocytotoxic effects in prostatic cancer.
    JAMA, 1972, Apr-10, Volume: 220, Issue:2

    Topics: Aminoglutethimide; Cytotoxicity Tests, Immunologic; Diethylstilbestrol; Glucocorticoids; Humans; Lym

1972
Effect of hormonal therapy on plasma testosterone levels in prostatic carcinoma.
    British medical journal, 1971, Nov-13, Volume: 4, Issue:5784

    Topics: Age Factors; Aged; Aminoglutethimide; Castration; Diethylstilbestrol; Estrogens; Humans; Male; Middl

1971
Effects of aminoglutethimide on the prostate glands of rats--a preliminary study.
    Canadian journal of surgery. Journal canadien de chirurgie, 1971, Volume: 14, Issue:2

    Topics: Adrenal Cortex Hormones; Adrenal Glands; Aminoglutethimide; Androgens; Aniline Compounds; Animals; A

1971