aminoglutethimide has been researched along with Cancer of Ovary in 3 studies
Aminoglutethimide: An aromatase inhibitor that is used in the treatment of advanced BREAST CANCER.
aminoglutethimide : A dicarboximide that is a six-membered cyclic compound having ethyl and 4-aminophenyl substituents at the 3-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Three sequential phase II trials were performed in patients with refractory epithelial ovarian carcinoma, using high-dose megestrol acetate (800 mg/d for 30 days, then 400 mg/d), high-dose tamoxifen (80 mg/d for 30 days, then 40 mg/d), and aminoglutethimide (1 g/d plus tapering doses of hydrocortisone)." | 5.07 | Hormonal palliation of chemoresistant ovarian cancer: three consecutive phase II trials of the Mid-Atlantic Oncology Program. ( Ahlgren, JD; Alt, D; Ellison, NM; Gottlieb, RJ; Laluna, F; Lokich, JJ; Sinclair, PR; Ueno, W; Wampler, GL; Yeung, KY, 1993) |
| " There is a tendency towards an increased response-rate with increased dosage of progestin, in both endometrial and breast carcinoma, while the route of administration appears to be of minor importance." | 2.37 | Progestin therapy of endometrial, breast and ovarian carcinoma. A review of clinical observations. ( Kauppila, A, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kauppila, A | 1 |
| Ahlgren, JD | 1 |
| Ellison, NM | 1 |
| Gottlieb, RJ | 1 |
| Laluna, F | 1 |
| Lokich, JJ | 1 |
| Sinclair, PR | 1 |
| Ueno, W | 1 |
| Wampler, GL | 1 |
| Yeung, KY | 1 |
| Alt, D | 1 |
| Eggenberger, C | 1 |
| Brändle, M | 1 |
| Galeazzi, RL | 1 |
| Spinas, GA | 1 |
| Schmid, C | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Multicentric, Randomized, Non Comparative, Open-label Phase I/II Evaluating AZD2014 (Dual Mammalian Target of Rapamycin Complex 1/2 (mTORC1/mTORC2) Inhibitor) in Combination With Anastrozole Versus Anastrozole Alone in the Treatment of Metastatic Hormon[NCT02730923] | Phase 1/Phase 2 | 72 participants (Anticipated) | Interventional | 2016-04-30 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for aminoglutethimide and Cancer of Ovary
| Article | Year |
|---|---|
Progestin therapy of endometrial, breast and ovarian carcinoma. A review of clinical observations.
Topics: Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Bromocriptine; | 1984 |
1 trial available for aminoglutethimide and Cancer of Ovary
| Article | Year |
|---|---|
Hormonal palliation of chemoresistant ovarian cancer: three consecutive phase II trials of the Mid-Atlantic Oncology Program.
Topics: Adenocarcinoma; Aminoglutethimide; Carcinoma; Drug Resistance; Drug Therapy, Combination; Female; Hu | 1993 |
1 other study available for aminoglutethimide and Cancer of Ovary
| Article | Year |
|---|---|
[Cushing syndrome due to ectopic ACTH secretion: an uncommon case presentation, diagnosis and therapy].
Topics: ACTH Syndrome, Ectopic; Adenocarcinoma; Aminoglutethimide; Antineoplastic Agents, Hormonal; Diagnost | 1999 |