aminoglutethimide has been researched along with Atypical Ductal Hyperplasia in 9 studies
Aminoglutethimide: An aromatase inhibitor that is used in the treatment of advanced BREAST CANCER.
aminoglutethimide : A dicarboximide that is a six-membered cyclic compound having ethyl and 4-aminophenyl substituents at the 3-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We describe sequential response to aminoglutethimide after eventual failure of treatment with tamoxifen in a patient with metastatic breast cancer." | 7.66 | Response to aminoglutethimide after tamoxifen therapy in advanced breast cancer. ( Allison, RW; Furnival, CM; Lee, JF; Roberts, SJ, 1982) |
| "Its role in the biology of breast cancer is unclear." | 5.26 | Effects of aminoglutethimide on delta 5-androstenediol metabolism in postmenopausal women with breast cancer. ( Bird, CE; Clark, AF; Masters, V; Sterns, EE, 1982) |
| "Aminoglutethimide is an investigational agent of proven benefit in the treatment of metastatic breast carcinoma." | 5.26 | Pancytopenia induced by aminoglutethimide in the treatment of breast cancer. ( Hamilton, R; Harvey, HA; Lawrence, B; Lipton, A; Mercurio, T; Santen, RJ, 1978) |
| "We report a case of radiotherapy-enhanced aminoglutethimide skin toxicity in a patient with metastatic breast cancer." | 3.68 | Radiotherapy enhances the toxicity of aminoglutethimide. ( Buzdar, AU; Hortobagyi, GN; Vanek, N, 1990) |
| "We describe sequential response to aminoglutethimide after eventual failure of treatment with tamoxifen in a patient with metastatic breast cancer." | 3.66 | Response to aminoglutethimide after tamoxifen therapy in advanced breast cancer. ( Allison, RW; Furnival, CM; Lee, JF; Roberts, SJ, 1982) |
| "This enzymatic shield protected the breast cancer cells from the antiproliferative action of GCS." | 1.30 | Inhibition of 11 beta-hydroxysteroid dehydrogenase activity enhances the antiproliferative effect of glucocorticosteroids on MCF-7 and ZR-75-1 breast cancer cells. ( Bühler, H; Hundertmark, S; Ragosch, V; Rudolf, M; Weitzel, HK, 1997) |
| "Its role in the biology of breast cancer is unclear." | 1.26 | Effects of aminoglutethimide on delta 5-androstenediol metabolism in postmenopausal women with breast cancer. ( Bird, CE; Clark, AF; Masters, V; Sterns, EE, 1982) |
| "Aminoglutethimide is an investigational agent of proven benefit in the treatment of metastatic breast carcinoma." | 1.26 | Pancytopenia induced by aminoglutethimide in the treatment of breast cancer. ( Hamilton, R; Harvey, HA; Lawrence, B; Lipton, A; Mercurio, T; Santen, RJ, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (66.67) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Allison, RW | 1 |
| Furnival, CM | 1 |
| Lee, JF | 1 |
| Roberts, SJ | 1 |
| Bird, CE | 1 |
| Masters, V | 1 |
| Sterns, EE | 1 |
| Clark, AF | 1 |
| Hundertmark, S | 1 |
| Bühler, H | 1 |
| Rudolf, M | 1 |
| Weitzel, HK | 1 |
| Ragosch, V | 1 |
| Lawrence, B | 1 |
| Santen, RJ | 1 |
| Lipton, A | 1 |
| Harvey, HA | 1 |
| Hamilton, R | 1 |
| Mercurio, T | 1 |
| Brown, PW | 1 |
| Terz, JJ | 1 |
| Henry, JA | 1 |
| Piggott, NH | 1 |
| Mallick, UK | 1 |
| Nicholson, S | 1 |
| Farndon, JR | 1 |
| Westley, BR | 1 |
| May, FE | 1 |
| Vanek, N | 1 |
| Hortobagyi, GN | 1 |
| Buzdar, AU | 1 |
| Mathijs, R | 1 |
| Coolen, D | 1 |
| Hermans-Debaive, C | 1 |
| Vincent, MD | 1 |
| Clink, HM | 1 |
| Coombes, RC | 1 |
| Smith, IE | 1 |
| Kandler, R | 1 |
| Powles, TJ | 1 |
1 trial available for aminoglutethimide and Atypical Ductal Hyperplasia
| Article | Year |
|---|---|
Aminoglutethimide (with hydrocortisone) induced agranulocytosis in primary breast cancer.
Topics: Aged; Agranulocytosis; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Breast Neo | 1985 |
8 other studies available for aminoglutethimide and Atypical Ductal Hyperplasia
| Article | Year |
|---|---|
Response to aminoglutethimide after tamoxifen therapy in advanced breast cancer.
Topics: Aminoglutethimide; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Drug Administration Sc | 1982 |
Effects of aminoglutethimide on delta 5-androstenediol metabolism in postmenopausal women with breast cancer.
Topics: Adenocarcinoma; Adult; Aminoglutethimide; Androstenediol; Androstenediols; Breast Neoplasms; Carcino | 1982 |
Inhibition of 11 beta-hydroxysteroid dehydrogenase activity enhances the antiproliferative effect of glucocorticosteroids on MCF-7 and ZR-75-1 breast cancer cells.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Administration, Topical; Aminoglutethimide; Analysis of Varia | 1997 |
Pancytopenia induced by aminoglutethimide in the treatment of breast cancer.
Topics: Aged; Aminoglutethimide; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Female; Humans; | 1978 |
Breast carcinoma associated with Klinefelter syndrome: a case report.
Topics: Adrenal Glands; Adult; Aminoglutethimide; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; | 1978 |
pNR-2/pS2 immunohistochemical staining in breast cancer: correlation with prognostic factors and endocrine response.
Topics: Aminoglutethimide; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Female; Humans; Immuno | 1991 |
Radiotherapy enhances the toxicity of aminoglutethimide.
Topics: Aminoglutethimide; Bone Neoplasms; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Drug E | 1990 |
Agranulocytosis induced by aminoglutethimide.
Topics: Aged; Agranulocytosis; Aminoglutethimide; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; | 1988 |