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aminoglutethimide and Aldosteronism

aminoglutethimide has been researched along with Aldosteronism in 14 studies

Aminoglutethimide: An aromatase inhibitor that is used in the treatment of advanced BREAST CANCER.
aminoglutethimide : A dicarboximide that is a six-membered cyclic compound having ethyl and 4-aminophenyl substituents at the 3-position.

Research Excerpts

ExcerptRelevanceReference
" by metyrapone test or by congenital adrenal hyperplasia resulting from 11 beta-hydroxylase deficiency."3.69An alternate pathway to androstenedione synthesis by human adrenals: evidence of a balance in 11 beta-hydroxylase and 17,20-lyase activities leading to androstenedione. ( Auzéby, A; Bogdan, A; Touitou, Y, 1995)
" Blood pressure was normal during treatment with spironolactone and during pregnancy, when the action of aldosterone and other similar steroids was presumably blocked by an increased production of progesterone; this suggests that the hypertension is dependent upon sodium-retaining steroids such as aldosterone."3.66Overproduction of sodium-retaining steroids by the zona glomerulosa is adrenocorticotropin-dependent and mediates hypertension in dexamethasone-suppressible aldosteronism. ( Bartter, FC; Gill, JR, 1981)
"The blood pressure elevation of primary aldosteronism is caused by excessive production of the known mineralocorticoid, aldosterone."2.64Are there unknown mineralocorticoids in low-renin essential hypertension? ( Hollifield, JW; Island, DP; Liddle, GW; Sennett, JA; Slaton, PE; Wilson, HM; Yarbro, L, 1977)
"The hypothesis that hyperaldosteronism is not the sole cause of hypertension in dexamethasone-suppressible hyperaldosteronsim was tested in an 18-year-old male."1.26Evidence for an unidentified ACTH-induced steroid hormone causing hypertension. ( Levine, LS; New, MI; Peterson, RE; Saenger, P, 1976)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-199013 (92.86)18.7374
1990's1 (7.14)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gill, JR1
Bartter, FC1
Sasaki, H1
Kawasaki, T1
Okumura, M1
Asano, T1
Abe, K1
Arakawa, K1
Auzéby, A1
Bogdan, A1
Touitou, Y1
New, MI1
Peterson, RE1
Saenger, P1
Levine, LS1
Neumann, P1
Knappe, G1
Stahl, F1
Kublun, G1
Bruns, W1
Wulfert, P1
Hollifield, JW1
Slaton, PE1
Wilson, HM1
Sennett, JA1
Yarbro, L1
Island, DP2
Liddle, GW3
Horký, K3
Gregorová, I3
Silinková-Malková, E1
Vancura, J1
Küchel, O3
Jiránková, J2
Matys, Z2
Fishman, LM1
Fleischer, N1
Werning, C2
Siegenthaler, W2
Philbert, M1
Luton, JP1
Mathieu de Fossey, B1
Bricaire, H1

Trials

1 trial available for aminoglutethimide and Aldosteronism

ArticleYear
Are there unknown mineralocorticoids in low-renin essential hypertension?
    Mayo Clinic proceedings, 1977, Volume: 52, Issue:5

    Topics: Aminoglutethimide; Blood Pressure; Clinical Trials as Topic; Humans; Hyperaldosteronism; Hypertensio

1977

Other Studies

13 other studies available for aminoglutethimide and Aldosteronism

ArticleYear
Overproduction of sodium-retaining steroids by the zona glomerulosa is adrenocorticotropin-dependent and mediates hypertension in dexamethasone-suppressible aldosteronism.
    The Journal of clinical endocrinology and metabolism, 1981, Volume: 53, Issue:2

    Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Adult; Aldosterone; Aminoglutethimide; Child, Preschool

1981
Bartter's syndrome: effect of indomethacin on prostaglandins, urinary kallikrein, renin-angiotensin-aldosterone system, and the response to angiotensin II antagonist.
    Endocrinologia japonica, 1980, Volume: 27, Issue:4

    Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Adult; Aldosterone; Aminoglutethimide; Angiotensin II; Aspi

1980
An alternate pathway to androstenedione synthesis by human adrenals: evidence of a balance in 11 beta-hydroxylase and 17,20-lyase activities leading to androstenedione.
    The Journal of clinical endocrinology and metabolism, 1995, Volume: 80, Issue:5

    Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adult

1995
Evidence for an unidentified ACTH-induced steroid hormone causing hypertension.
    The Journal of clinical endocrinology and metabolism, 1976, Volume: 43, Issue:6

    Topics: 18-Hydroxydesoxycorticosterone; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Aldoste

1976
[The effect of aminoglutethimide in the treatment of adrenal gland hyperfunction].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1979, May-01, Volume: 34, Issue:9

    Topics: Adenoma; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Adult; Aminoglutethimide; Cushin

1979
Differential diagnosis of primary and pseudoprimary hyperaldosteronism.
    Review of Czechoslovak medicine, 1976, Volume: 22, Issue:4

    Topics: Adrenocortical Hyperfunction; Adult; Aminoglutethimide; Diagnosis, Differential; Female; Humans; Hyp

1976
[Clinical experiences with aminoglutethimide (Elipten), a new inhibitor of steroid biosynthesis in the adrenal gland].
    Schweizerische medizinische Wochenschrift, 1968, Nov-23, Volume: 98, Issue:47

    Topics: Adrenal Gland Neoplasms; Adrenal Glands; Adrenal Rest Tumor; Adult; Aminoglutethimide; Aniline Compo

1968
Effects of amino-glutethimide on adrenal function in man.
    The Journal of clinical endocrinology and metabolism, 1967, Volume: 27, Issue:4

    Topics: 17-Hydroxycorticosteroids; Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hor

1967
[Therapy of secondary hyperaldosteronism].
    Minerva medica, 1973, Mar-14, Volume: 64, Issue:14

    Topics: Aminoglutethimide; Butanones; Heparin; Humans; Hyperaldosteronism; Metyrapone; Mineralocorticoid Rec

1973
[Treatment of secondary hyperaldosteronism].
    Deutsche medizinische Wochenschrift (1946), 1969, Oct-03, Volume: 94, Issue:40

    Topics: Adrenalectomy; Aldosterone; Aminoglutethimide; Aniline Compounds; Anticonvulsants; Diuretics; Humans

1969
Management of aldosteronism.
    American journal of clinical pathology, 1970, Volume: 54, Issue:3

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Aminoglutethimide; Humans; Hyperaldosteronism; Min

1970
[Corticosteroidogenesis inhibitors. II. A new cortico-adrenal inhibitor: amino-glutethimide (16,038Ba)].
    La Presse medicale, 1968, May-11, Volume: 76, Issue:23

    Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal G

1968
[Inhibitions of steroid biosynthesis in the adrenal gland by aminogluthetimide (Elipten CIBA) and its practical significance].
    Vnitrni lekarstvi, 1969, Volume: 15, Issue:5

    Topics: 17-Ketosteroids; Adrenal Glands; Aminoglutethimide; Aniline Compounds; Anticonvulsants; Cushing Synd

1969