aminoglutethimide has been researched along with Agranulocytosis in 8 studies
Aminoglutethimide: An aromatase inhibitor that is used in the treatment of advanced BREAST CANCER.
aminoglutethimide : A dicarboximide that is a six-membered cyclic compound having ethyl and 4-aminophenyl substituents at the 3-position.
Agranulocytosis: A decrease in the number of GRANULOCYTES; (BASOPHILS; EOSINOPHILS; and NEUTROPHILS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Aminoglutethimide (AG) is a first-generation aromatase inhibitor used for estrogen-dependent breast cancer." | 5.34 | Aminoglutethimide-induced protein free radical formation on myeloperoxidase: a potential mechanism of agranulocytosis. ( Bonini, MG; Ehrenshaft, M; Jiang, J; Mason, RP; Siraki, AG, 2007) |
| "Aminoglutethimide (AMG) is an aromatic amine aromatase inhibitor associated with a high incidence of idiosyncratic blood dyscrasias, especially agranulocytosis." | 3.79 | Effect of aminoglutethimide on neutrophils in rats: implications for idiosyncratic drug-induced blood dyscrasias. ( Ng, W; Uetrecht, J, 2013) |
| "G-CSF was applied in three patients with acute, iatrogenic, immunological agranulocytosis (after ticlopidine, thimazol and aminoglutethimide) complicated by severe infections." | 3.69 | [Treatment of drug induced agranulocytosis with granulocyte-macrophage colony stimulating factor (G-CSF)]. ( Kotlarek-Haus, S; Podolak-Dawidziak, M; Wróbel, T, 1994) |
| "Aminoglutethimide (AG) is a first-generation aromatase inhibitor used for estrogen-dependent breast cancer." | 1.34 | Aminoglutethimide-induced protein free radical formation on myeloperoxidase: a potential mechanism of agranulocytosis. ( Bonini, MG; Ehrenshaft, M; Jiang, J; Mason, RP; Siraki, AG, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (62.50) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ng, W | 1 |
| Uetrecht, J | 1 |
| Siraki, AG | 1 |
| Bonini, MG | 1 |
| Jiang, J | 1 |
| Ehrenshaft, M | 1 |
| Mason, RP | 1 |
| Kotlarek-Haus, S | 1 |
| Podolak-Dawidziak, M | 1 |
| Wróbel, T | 1 |
| Mathijs, R | 1 |
| Coolen, D | 1 |
| Hermans-Debaive, C | 1 |
| Vincent, MD | 1 |
| Clink, HM | 1 |
| Coombes, RC | 1 |
| Smith, IE | 2 |
| Kandler, R | 1 |
| Powles, TJ | 1 |
| Harris, AL | 1 |
| Hughes, G | 1 |
| Barrett, AJ | 1 |
| Abusrewil, S | 1 |
| Dowsett, M | 1 |
| van der Heijden, JT | 1 |
| Splinter, TA | 1 |
| Caldwell, G | 1 |
| Bradbury, A | 1 |
| Toft, AD | 1 |
1 trial available for aminoglutethimide and Agranulocytosis
| Article | Year |
|---|---|
Aminoglutethimide (with hydrocortisone) induced agranulocytosis in primary breast cancer.
Topics: Aged; Agranulocytosis; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Breast Neo | 1985 |
7 other studies available for aminoglutethimide and Agranulocytosis
| Article | Year |
|---|---|
Effect of aminoglutethimide on neutrophils in rats: implications for idiosyncratic drug-induced blood dyscrasias.
Topics: Agranulocytosis; Aminoglutethimide; Animals; Antigens, CD; Apoptosis; Bone Marrow; Bone Marrow Cells | 2013 |
Aminoglutethimide-induced protein free radical formation on myeloperoxidase: a potential mechanism of agranulocytosis.
Topics: Adenosine Triphosphate; Agranulocytosis; Aminoglutethimide; Aniline Compounds; Aromatase Inhibitors; | 2007 |
[Treatment of drug induced agranulocytosis with granulocyte-macrophage colony stimulating factor (G-CSF)].
Topics: Adult; Agranulocytosis; Aminoglutethimide; Female; Granulocyte Colony-Stimulating Factor; Humans; Le | 1994 |
Agranulocytosis induced by aminoglutethimide.
Topics: Aged; Agranulocytosis; Aminoglutethimide; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; | 1988 |
Agranulocytosis associated with aminoglutethimide: pharmacological and marrow studies.
Topics: Agranulocytosis; Aminoglutethimide; Bone Marrow; Breast Neoplasms; Female; Granulocytes; Humans; Mac | 1986 |
Aminoglutethimide-induced myelosuppression.
Topics: Adenocarcinoma; Aged; Agranulocytosis; Aminoglutethimide; Breast Neoplasms; Female; Humans | 1986 |
Aminoglutethimide induced agranulocytosis in breast cancer.
Topics: Aged; Agranulocytosis; Aminoglutethimide; Breast Neoplasms; Female; Humans | 1985 |