Page last updated: 2024-10-22

aminoglutethimide and Adrenal Gland Hyperfunction

aminoglutethimide has been researched along with Adrenal Gland Hyperfunction in 30 studies

Aminoglutethimide: An aromatase inhibitor that is used in the treatment of advanced BREAST CANCER.
aminoglutethimide : A dicarboximide that is a six-membered cyclic compound having ethyl and 4-aminophenyl substituents at the 3-position.

Research Excerpts

ExcerptRelevanceReference
"Five cases of congenital adrenal hyperplasia due to C21-hydroxylase defect were treated with a combination of aminoglutethimide and prednisolone."7.65Long-term effects of aminoglutethimide on steroid metabolism in congenital adrenal hyperplasia. ( Hamilton, W, 1976)
"Surgery with immediate adjuvant long term mitotane administration was the most effective form of therapy for patients with adrenocortical carcinoma."3.69Adrenocortical carcinoma. A clinical study and treatment results of 52 patients. ( Kasperlik-Załuska, AA; Makowska, AM; Migdalska, BM; Zgliczyński, S, 1995)
"Five cases of congenital adrenal hyperplasia due to C21-hydroxylase defect were treated with a combination of aminoglutethimide and prednisolone."3.65Long-term effects of aminoglutethimide on steroid metabolism in congenital adrenal hyperplasia. ( Hamilton, W, 1976)
"We report three cases of long-term treatment of ectopic ACTH syndrome due to metastatic bronchial carcinoid, islet cell carcinoma, and malignant thymoma tumors."2.40Long-term medical treatment of ectopic ACTH syndrome. ( Comi, RJ; Gorden, P, 1998)
"Aminoglutethimide was administered daily at a dose of 15 mg/kg bodyweight for one month."1.31Use of aminoglutethimide in the treatment of pituitary-dependent hyperadrenocorticism in the dog. ( Guerrero, B; Melián, C; Peña, L; Pérez, AM; Ynaraja, E, 2002)
" Clinical improvements have been achieved in ten of the thirteen cases over a therapeutic course of 8 to 12 wk with a daily dosage of 1."1.28[Clinical observation on hypercortisolism treated with amino-glutethimide]. ( Cai, F; Cheng, YM; Li, XJ; Li, Y; Liang, JZ; Tian, HM; Yang, DP; Yu, ZL, 1989)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199026 (86.67)18.7374
1990's3 (10.00)18.2507
2000's1 (3.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schteingart, DE1
Conn, JW1
Jacobelli, A1
Agostino, A1
Altomonte, G1
Beccati, MD1
Degli Azzi Vitelleschi, I1
Marangolo, M1
Chen, JL1
Kasperlik-Załuska, AA1
Migdalska, BM1
Zgliczyński, S1
Makowska, AM1
Comi, RJ1
Gorden, P1
Pérez, AM1
Guerrero, B1
Melián, C1
Ynaraja, E1
Peña, L1
Falke, HE1
Degenhart, HJ1
Abeln, GJ1
Visser, HK1
Neumann, P1
Knappe, G1
Stahl, F1
Kublun, G1
Bruns, W1
Wulfert, P1
Motlík, K2
Marek, J1
Stárka, L3
Horký, K2
Gregorová, I1
Silinková-Malková, E1
Vancura, J1
Hamilton, W2
Murphy, BE1
Li, XJ1
Liang, JZ1
Tian, HM1
Li, Y1
Cai, F1
Yang, DP1
Cheng, YM1
Yu, ZL1
Carey, RM1
Orth, DN1
Hartmann, WH1
Küchel, O1
Gregorvá, I1
Smilo, RP1
Earll, JM1
Forsham, PH1
Hartwig, W2
Migdalska, B2
Kasperlik-Zaluska, A1
Kasperlik-Zasluska, A1
Brun, J1
Revol, A1
Queneau, P1
Schreiber, V1
Zbuzek, V1
Zbuzková-Kmentová, V1
McMillan, M1
Maisey, MN1
Raith, L2
Touitou, Y1
Legrand, JC1
Desgrez, P1
Hughss, SW1
Burley, DM1
Miranda-Zetterstrand, N1
Díaz-Bonet, L1
Pagán-Sáez, H1
Rosaly de Jirau, W1
Bricaire, H1
Albeaux-Fernet, M1
Lumbroso, P1
Netter, A1
Sebaoun, J1

Reviews

2 reviews available for aminoglutethimide and Adrenal Gland Hyperfunction

ArticleYear
Long-term medical treatment of ectopic ACTH syndrome.
    Southern medical journal, 1998, Volume: 91, Issue:11

    Topics: ACTH Syndrome, Ectopic; Adolescent; Adrenocortical Hyperfunction; Aminoglutethimide; Antineoplastic

1998
Aminoglutethimide: a "side-effect" turned to therapeutic advantage.
    Postgraduate medical journal, 1970, Volume: 46, Issue:537

    Topics: Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Insufficiency; Adrenocortical Hyperfunctio

1970

Trials

2 trials available for aminoglutethimide and Adrenal Gland Hyperfunction

ArticleYear
Treatment of major depression with steroid suppressive drugs.
    The Journal of steroid biochemistry and molecular biology, 1991, Volume: 39, Issue:2

    Topics: Adrenocortical Hyperfunction; Adult; Aged; Aminoglutethimide; Cushing Syndrome; Depressive Disorder;

1991
Qualitative alterations in urinary 17-ketosteroid excretion during aminoglutethimide administration.
    The Journal of clinical endocrinology and metabolism, 1969, Volume: 29, Issue:2

    Topics: 17-Ketosteroids; Adrenocortical Hyperfunction; Aminoglutethimide; Androsterone; Aniline Compounds; A

1969

Other Studies

26 other studies available for aminoglutethimide and Adrenal Gland Hyperfunction

ArticleYear
Effects of aminoglutethimide upon adrenal function and cortisol metabolism in Cushing's syndrome.
    The Journal of clinical endocrinology and metabolism, 1967, Volume: 27, Issue:12

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Glands; Adrenocortical Hyperfunction

1967
[Treatment of glycoactive hypercorticism].
    La Clinica terapeutica, 1984, Nov-30, Volume: 111, Issue:4

    Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; A

1984
[Pharmacological suppression of the adrenal gland. Considerations on a clinical case].
    La Clinica terapeutica, 1982, Jul-31, Volume: 102, Issue:2

    Topics: Adenocarcinoma, Mucinous; Adrenocortical Hyperfunction; Adult; Aminoglutethimide; Antineoplastic Age

1982
[Preliminary results of treatment of hypercorticism with aminoglutethimide].
    Zhonghua nei ke za zhi, 1982, Volume: 21, Issue:12

    Topics: Adolescent; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocortical Hyperfunction; Adult; Aminoglute

1982
Adrenocortical carcinoma. A clinical study and treatment results of 52 patients.
    Cancer, 1995, May-15, Volume: 75, Issue:10

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Cortex Neoplasms; Adrenocortical Car

1995
Use of aminoglutethimide in the treatment of pituitary-dependent hyperadrenocorticism in the dog.
    The Journal of small animal practice, 2002, Volume: 43, Issue:3

    Topics: Adrenal Glands; Adrenergic Agents; Adrenocortical Hyperfunction; Aminoglutethimide; Animals; Dog Dis

2002
Effects of 25-hydroxycholesterol and aminoglutethimide in isolated rat adrenal cells. A model for congenital lipoid adrenal hyperplasia?
    Molecular and cellular endocrinology, 1976, Volume: 4, Issue:2

    Topics: Adrenal Glands; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Aminoglutethimide; Animal

1976
[The effect of aminoglutethimide in the treatment of adrenal gland hyperfunction].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1979, May-01, Volume: 34, Issue:9

    Topics: Adenoma; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Adult; Aminoglutethimide; Cushin

1979
Influence of single peroral dose of aminoglutethimide on the rat adrenal cortex.
    Endocrinologia experimentalis, 1977, Volume: 11, Issue:4

    Topics: Adrenal Cortex; Adrenocortical Hyperfunction; Aminoglutethimide; Animals; Corticosterone; Female; Ra

1977
Differential diagnosis of primary and pseudoprimary hyperaldosteronism.
    Review of Czechoslovak medicine, 1976, Volume: 22, Issue:4

    Topics: Adrenocortical Hyperfunction; Adult; Aminoglutethimide; Diagnosis, Differential; Female; Humans; Hyp

1976
Long-term effects of aminoglutethimide on steroid metabolism in congenital adrenal hyperplasia.
    Clinica chimica acta; international journal of clinical chemistry, 1976, Nov-15, Volume: 73, Issue:1

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Hyperplasia, Congenital; Adrenocortical Hyperfun

1976
[Clinical observation on hypercortisolism treated with amino-glutethimide].
    Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao, 1989, Volume: 20, Issue:1

    Topics: Adolescent; Adrenocortical Hyperfunction; Adult; Aminoglutethimide; Appetite; Bone and Bones; Female

1989
Malignant melanoma with ectopic production of adrenocorticotropic hormone. Palliative treatment with inhibitors of adrenal steroid biosynthesis.
    The Journal of clinical endocrinology and metabolism, 1973, Volume: 36, Issue:3

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocortical Hyperfunction; Adrenocorticotropic Hormon

1973
Suppression of tumorous adrenal hyperfunction by aminoglutethimide.
    Metabolism: clinical and experimental, 1967, Volume: 16, Issue:4

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma; Adrenal Gland Neoplasms; Adrenocortical Hyperfu

1967
[Effect of aminoglutethimide on excretion of ACTH and adrenal hormones].
    Polskie Archiwum Medycyny Wewnetrznej, 1968, Volume: 41, Issue:2

    Topics: 17-Hydroxycorticosteroids; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Aminoglutethim

1968
Effect of aminogluthethymide on urinary excretion of corticotropin and adrenal hormones.
    Polish medical journal, 1969, Volume: 8, Issue:3

    Topics: Adolescent; Adrenal Glands; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Adult; Aminog

1969
[Broncho-pulmonary cancer with true or degraded hypercorticism].
    La Presse medicale, 1969, Nov-29, Volume: 77, Issue:51

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocortical Hyperfunction; Adrenocorticotropic Hormon

1969
Reactions of the rat and hamster endocrine system to aminoglutethimide.
    Physiologia Bohemoslovaca, 1969, Volume: 18, Issue:3

    Topics: Adrenal Glands; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Aminoglutethimide; Anilin

1969
Effects of aminoglutethimide in a case of ectopic ACTH syndrome. Influence on steroid metabolism.
    Acta endocrinologica, 1970, Volume: 64, Issue:4

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Glands; Adrenocortical Hyperfunction; Adrenocort

1970
[Medical therapy of hyperadrenalism].
    Minerva medica, 1973, Mar-14, Volume: 64, Issue:14

    Topics: Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Aminoglutethimide; Cushing Syndrome; Huma

1973
Adrenocortical steroidogenesis and aminoglutethimide (A. G.). II. Cytochemical and ultrastructural changes. Pratical and theoretical values.
    Biomedicine / [publiee pour l'A.A.I.C.I.G.], 1973, Volume: 18, Issue:4

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocortical Hyperfunction; Adrenocorticotropic

1973
[Drug therapy of adrenal gland hyperfunction].
    Deutsche medizinische Wochenschrift (1946), 1972, Mar-24, Volume: 97, Issue:12

    Topics: Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenocortical Hyperfunction; Aminoglutethimide; A

1972
The treatment of congenital adrenal hyperplasia with aminoglutethimide.
    The Quarterly journal of medicine, 1971, Volume: 40, Issue:160

    Topics: Adrenal Hyperplasia, Congenital; Adrenocortical Hyperfunction; Aminoglutethimide; Aniline Compounds;

1971
Amino-glutethimide (elipten) in adenocortical carcinoma.
    Boletin de la Asociacion Medica de Puerto Rico, 1968, Volume: 60, Issue:12

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Gland Neoplasms; Adrenocortical Hyperfunction; A

1968
[Present knowledge on the treatment of Cushing's syndrome].
    La Presse medicale, 1969, Nov-01, Volume: 77, Issue:46

    Topics: Adrenalectomy; Adrenocortical Hyperfunction; Aminoglutethimide; Cushing Syndrome; Dichlorodiphenyldi

1969
The influence of injected aminoglutethimide on the morphology of the rat adrenal cortex and adrenal metabolism of progesterone.
    Endokrinologie, 1971, Volume: 58, Issue:1

    Topics: Adrenal Glands; Adrenocortical Hyperfunction; Aminoglutethimide; Aniline Compounds; Animals; Anticon

1971