Compounds > aminoglutethimide
Page last updated: 2024-10-22

aminoglutethimide and Adrenal Cancer

aminoglutethimide has been researched along with Adrenal Cancer in 30 studies

Aminoglutethimide: An aromatase inhibitor that is used in the treatment of advanced BREAST CANCER.
aminoglutethimide : A dicarboximide that is a six-membered cyclic compound having ethyl and 4-aminophenyl substituents at the 3-position.

Research Excerpts

ExcerptRelevanceReference
"Fifteen patients with endogenous Cushing's syndrome were treated with metyrapone and/or amino-glutethimide."9.05Aminoglutethimide and metyrapone in the management of Cushing's syndrome. ( Adamson, U; Sjöberg, HE; Thorén, M, 1985)
"Fifteen patients with endogenous Cushing's syndrome were treated with metyrapone and/or amino-glutethimide."5.05Aminoglutethimide and metyrapone in the management of Cushing's syndrome. ( Adamson, U; Sjöberg, HE; Thorén, M, 1985)
" by metyrapone test or by congenital adrenal hyperplasia resulting from 11 beta-hydroxylase deficiency."3.69An alternate pathway to androstenedione synthesis by human adrenals: evidence of a balance in 11 beta-hydroxylase and 17,20-lyase activities leading to androstenedione. ( Auzéby, A; Bogdan, A; Touitou, Y, 1995)
"About one third of patients with breast cancer show objective improvement with aminoglutethimide, and it may also be of use in the treatment of adrenal carcinoma."2.37Aminoglutethimide and ketoconazole: historical perspectives and future prospects. ( Nicholls, PJ; Shaw, MA; Smith, HJ, 1988)
"Cytochalasin B did not inhibit protein synthesis or transport of [3H]-cholesterol into the cells nor did it alter total cell concentration of ATP."1.26Response of adrenal tumor cells to adrenocorticotropin: site of inhibition by cytochalasin B. ( Hall, PF; Mrotek, JJ, 1977)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199027 (90.00)18.7374
1990's3 (10.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jacobelli, A1
Agostino, A1
Altomonte, G1
Nakamura, M2
Watanuki, M2
Tilley, BE1
Hall, PF3
Chen, JL1
Bricaire, H2
Luton, JP2
Freeman, DA1
Auzéby, A1
Bogdan, A1
Touitou, Y2
Mrotek, JJ1
Cortese, F1
Wolf, J1
deAsis, DN1
Samaan, NA1
Scott, RD1
Kong, HL1
Lee, KO1
Cheah, JS1
Shaw, MA1
Nicholls, PJ1
Smith, HJ1
Thorén, M1
Adamson, U1
Sjöberg, HE1
Horký, K1
Küchel, O2
Gregorová, I1
Jiránková, J1
Matys, Z1
Fishman, LM1
Liddle, GW3
Island, DP1
Fleischer, N1
Smilo, RP1
Earll, JM1
Forsham, PH1
Kowal, J1
Orth, DN1
Masui, H1
Garren, LD1
Schein, PS1
Temple, R1
Wolff, J1
Legrand, JC1
Desgrez, P1
Geyer, G1
Hughss, SW1
Burley, DM1
Raith, L1
Miranda-Zetterstrand, N1
Díaz-Bonet, L1
Pagán-Sáez, H1
Rosaly de Jirau, W1
Philbert, M1
Mathieu de Fossey, B1
Schteingart, DE1
Cash, R1
Conn, JW1

Reviews

4 reviews available for aminoglutethimide and Adrenal Cancer

ArticleYear
Aminoglutethimide and ketoconazole: historical perspectives and future prospects.
    Journal of steroid biochemistry, 1988, Volume: 31, Issue:1

    Topics: Adrenal Gland Neoplasms; Aminoglutethimide; Aromatase Inhibitors; Breast Neoplasms; Fadrozole; Femal

1988
Chemotherapeutic management of the hormone-secreting endocrine malignancies.
    Cancer, 1972, Volume: 30, Issue:6

    Topics: Adenoma, Islet Cell; Adrenal Gland Neoplasms; Aminoglutethimide; Aniline Compounds; Antibiotics, Ant

1972
[Cushing's syndrome].
    Annals of the New York Academy of Sciences, 1973, Jun-15, Volume: 214

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Aminoglutethimide; Cushing Syndrome

1973
Aminoglutethimide: a "side-effect" turned to therapeutic advantage.
    Postgraduate medical journal, 1970, Volume: 46, Issue:537

    Topics: Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Insufficiency; Adrenocortical Hyperfunctio

1970

Trials

1 trial available for aminoglutethimide and Adrenal Cancer

ArticleYear
Aminoglutethimide and metyrapone in the management of Cushing's syndrome.
    Acta endocrinologica, 1985, Volume: 109, Issue:4

    Topics: ACTH Syndrome, Ectopic; Adolescent; Adrenal Gland Neoplasms; Adult; Aminoglutethimide; Clinical Tria

1985

Other Studies

25 other studies available for aminoglutethimide and Adrenal Cancer

ArticleYear
[Treatment of glycoactive hypercorticism].
    La Clinica terapeutica, 1984, Nov-30, Volume: 111, Issue:4

    Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; A

1984
Effect of adrenocorticotrophin on intracellular cholesterol transport.
    The Journal of endocrinology, 1980, Volume: 84, Issue:2

    Topics: Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Aminoglutethimide; Anaerobiosis; Animals; Biol

1980
[Preliminary results of treatment of hypercorticism with aminoglutethimide].
    Zhonghua nei ke za zhi, 1982, Volume: 21, Issue:12

    Topics: Adolescent; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocortical Hyperfunction; Adult; Aminoglute

1982
[Cushing's syndrome. Medical treatment of adrenal hypercorticism].
    Hormone research, 1980, Volume: 13, Issue:4-5

    Topics: Adrenal Gland Neoplasms; Aminoglutethimide; Androstanols; Bromocriptine; Cushing Syndrome; Cyprohept

1980
Adrenal carcinoma.
    Current therapy in endocrinology and metabolism, 1994, Volume: 5

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Aminoglutethimide; Carcinoma; Cushing Syndrome; Dia

1994
An alternate pathway to androstenedione synthesis by human adrenals: evidence of a balance in 11 beta-hydroxylase and 17,20-lyase activities leading to androstenedione.
    The Journal of clinical endocrinology and metabolism, 1995, Volume: 80, Issue:5

    Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adult

1995
Response of adrenal tumor cells to adrenocorticotropin: site of inhibition by cytochalasin B.
    Biochemistry, 1977, Jul-12, Volume: 16, Issue:14

    Topics: 20-alpha-Dihydroprogesterone; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Aminoglutethimid

1977
Cytochalasin-stimulated steroidogenesis from high density lipoproteins.
    The Journal of cell biology, 1978, Volume: 77, Issue:2

    Topics: 20-alpha-Dihydroprogesterone; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Aminoglutethimid

1978
On the role of protein synthesis in the response of adrenal tumor cells to ACTH.
    Molecular and cellular endocrinology, 1978, Volume: 12, Issue:2

    Topics: Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Aminoglutethimide; Bucladesine; Cell Line; Chl

1978
Feminizing adrenocortical carcinoma with Cushing's syndrome and pseudohyperparathyroidism.
    Archives of internal medicine, 1978, Volume: 138, Issue:2

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adult

1978
Treatment of an adrenal cortical carcinoma with a combination of o,p'-DDD and aminoglutethimide.
    Postgraduate medical journal, 1975, Volume: 51, Issue:591

    Topics: 11-Hydroxycorticosteroids; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenalectomy; Adult;

1975
Medical treatment of Cushing's syndrome with aminoglutethimide and ketoconazole.
    Singapore medical journal, 1992, Volume: 33, Issue:5

    Topics: Adenoma; Adrenal Gland Neoplasms; Aminoglutethimide; Cushing Syndrome; Humans; Hydrocortisone; Ketoc

1992
[Clinical experiences with aminoglutethimide (Elipten), a new inhibitor of steroid biosynthesis in the adrenal gland].
    Schweizerische medizinische Wochenschrift, 1968, Nov-23, Volume: 98, Issue:47

    Topics: Adrenal Gland Neoplasms; Adrenal Glands; Adrenal Rest Tumor; Adult; Aminoglutethimide; Aniline Compo

1968
Effects of amino-glutethimide on adrenal function in man.
    The Journal of clinical endocrinology and metabolism, 1967, Volume: 27, Issue:4

    Topics: 17-Hydroxycorticosteroids; Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hor

1967
Suppression of tumorous adrenal hyperfunction by aminoglutethimide.
    Metabolism: clinical and experimental, 1967, Volume: 16, Issue:4

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma; Adrenal Gland Neoplasms; Adrenocortical Hyperfu

1967
Adrenal cells in tissue culture. IV. Use of an inhibitor of steroid synthesis for the study of ACTH action.
    Endocrinology, 1969, Volume: 85, Issue:2

    Topics: Acetates; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Aminoglutet

1969
Results of treatment in 108 patients with Cushing's syndrome.
    The New England journal of medicine, 1971, Jul-29, Volume: 285, Issue:5

    Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenalectomy; Adrenocorticotropic Hormone; Adult; Age

1971
Inhibition of replication in functional mouse adrenal tumor cells by adrenocorticotropic hormone mediated by adenosine 3':5'-cyclic monophosphate.
    Proceedings of the National Academy of Sciences of the United States of America, 1971, Volume: 68, Issue:12

    Topics: Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Aminoglutethimide; Animals; An

1971
Stimulation of steroid secretion by antimicrotubular agents.
    The Journal of biological chemistry, 1973, Apr-25, Volume: 248, Issue:8

    Topics: Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Aminoglutethimide; Animals; Cell Line; Chromat

1973
Adrenocortical steroidogenesis and aminoglutethimide (A. G.). II. Cytochemical and ultrastructural changes. Pratical and theoretical values.
    Biomedicine / [publiee pour l'A.A.I.C.I.G.], 1973, Volume: 18, Issue:4

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocortical Hyperfunction; Adrenocorticotropic

1973
[Drug therapy of adrenal gland hyperfunction].
    Deutsche medizinische Wochenschrift (1946), 1972, Mar-24, Volume: 97, Issue:12

    Topics: Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenocortical Hyperfunction; Aminoglutethimide; A

1972
Amino-glutethimide (elipten) in adenocortical carcinoma.
    Boletin de la Asociacion Medica de Puerto Rico, 1968, Volume: 60, Issue:12

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Gland Neoplasms; Adrenocortical Hyperfunction; A

1968
Management of aldosteronism.
    American journal of clinical pathology, 1970, Volume: 54, Issue:3

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Aminoglutethimide; Humans; Hyperaldosteronism; Min

1970
[Corticosteroidogenesis inhibitors. II. A new cortico-adrenal inhibitor: amino-glutethimide (16,038Ba)].
    La Presse medicale, 1968, May-11, Volume: 76, Issue:23

    Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal G

1968
Amino-glutethimide and metastatic adrenal cancer. Maintained reversal (six months) of Cushing's syndrome.
    JAMA, 1966, Nov-28, Volume: 198, Issue:9

    Topics: Adrenal Gland Neoplasms; Adult; Aminoglutethimide; Anticonvulsants; Antineoplastic Agents; Carbon Is

1966