Compounds > aminochrome 1

Page last updated: 2024-09-05

aminochrome 1 and Parkinson Disease

aminochrome 1 has been researched along with Parkinson Disease in 17 studies

Research

Studies (17)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (5.88)	18.2507
2000's	7 (41.18)	29.6817
2010's	7 (41.18)	24.3611
2020's	2 (11.76)	2.80

Authors

Authors	Studies
Almeida, ÁMAN; Barbosa, DB; Cardim-Pires, TR; Costa, ACS; Costa, SL; da Rocha Pita, SS; de Fátima Dias Costa, M; do Bomfim, MR; Dos Santos Junior, MC; Foguel, D; Fonseca-Fonseca, LA; Leite, FHA; Muñoz, P; Núñez-Figueredo, Y; Ochoa-Rodríguez, E; Outeiro, TF; Palhano, FL; Santos, CC; Segura-Aguilar, J; Shvachiy, L; Silva, VDA; Teles-Souza, J	1
Costa, ACS; Costa, SL; Cuenca-Bermejo, L; De Araújo, FM; de Fatima Dias Costa, M; de Jesus, LB; Farias, AA; Ferreira, KMS; Frota, AF; Herrero, MT; Menezes-Filho, JA; Munoz, P; Sanches, FS; Santos, CC; Segura-Aguilar, J; Silva, VDA; Soares, EN; Souza, JT	1
Costa, SL; D Costa, MF; de Araújo, FM; Dos Santos, CC; E Silva, JHC; El-Bachá, RS; Ferreira, RS; Fonseca, JCM; Gasparotto, J; Gelain, DP; Rodrigues, TLRS; Segura-Aguilar, J; Silva, VDA; Souza, CS	1
Ferrari, E; Muñoz, P; Paris, I; Segura-Aguilar, J; Zecca, L; Zucca, FA	1
Muñoz, P; Paris, I; Segura-Aguilar, J	1
Breckenridge, JM; Macarthur, H; Touchette, JC; Wilken, GH	1
Abarca, J; Cardenas, C; Díaz-Veliz, G; Gysling, K; Herrera, A; Hultenby, K; Inzunza, J; Jaña, F; Mora, S; Muñoz, P; Paris, I; Raisman-Vozari, R; Segura-Aguilar, J; Steinbusch, HW	1
Lim, TM; Zhou, ZD	1
Lozano, J; Muñoz, P; Paris, I; Perez-Pastene, C; Segura-Aguilar, J	1
Greenamyre, JT; Muñoz, P; Paris, I; Sanders, LH; Segura-Aguilar, J	1
Caviedes, P; Cuevas, C; Huenchuguala, S; Muñoz, P; Paris, I; Segura-Aguilar, J; Tizabi, Y; Villa, M	1
Arslan, P; Boschetto, R; Burlina, AP; De Iuliis, A; Galzigna, L; Zambenedetti, P	1
Alexandre, A; Toscano, P; Zoccarato, F	1
Giasson, BI; Hodara, R; Ischiropoulos, H; Lee, VM; Norris, EH; Trojanowski, JQ; Xu, S	1
Cardenas, S; Caviedes, P; Graumann, R; Lozano, J; Paris, I; Perez-Pastene, C; Riveros, A; Segura-Aguilar, J	1
Smythies, J	1
Azar, CO; Bennett, LB; Caviedes, P; Caviedes, R; Dagnino-Subiabre, A; Marcelain, K; Paris, I; Segura-Aguilar, J	1

Reviews

4 review(s) available for aminochrome 1 and Parkinson Disease

Article	Year
Protective and toxic roles of dopamine in Parkinson's disease. Journal of neurochemistry, 2014, Volume: 129, Issue:6 Topics: Animals; Dopamine; Glutathione; Humans; Indolequinones; Melanins; Monoamine Oxidase; Parkinson Disease; Quinones	2014
Aminochrome as New Preclinical Model to Find New Pharmacological Treatment that Stop the Development of Parkinson's Disease. Current medicinal chemistry, 2016, Volume: 23, Issue:4 Topics: Animals; Dopamine; Drug Discovery; Humans; Indolequinones; Oxidation-Reduction; Parkinson Disease	2016
Aminochrome as a preclinical experimental model to study degeneration of dopaminergic neurons in Parkinson's disease. Neurotoxicity research, 2007, Volume: 12, Issue:2 Topics: Animals; Disease Models, Animal; Dopamine; Humans; Indolequinones; Nerve Degeneration; Parkinson Disease	2007
On the functional of neuromelanin. Proceedings. Biological sciences, 1996, Apr-22, Volume: 263, Issue:1369 Topics: Brain; Catecholamines; Humans; Indolequinones; Indoles; Melanins; Models, Neurological; Neurons; Neurotoxins; Parkinson Disease; Schizophrenia	1996

Other Studies

13 other study(ies) available for aminochrome 1 and Parkinson Disease

Article	Year
JM-20, a Benzodiazepine-Dihydropyridine Hybrid Molecule, Inhibits the Formation of Alpha-Synuclein-Aggregated Species. Neurotoxicity research, 2022, Volume: 40, Issue:6 Topics: alpha-Synuclein; Benzodiazepines; Dihydropyridines; Humans; Molecular Docking Simulation; Neuroblastoma; Parkinson Disease	2022
Protective Effects of Flavonoid Rutin Against Aminochrome Neurotoxicity. Neurotoxicity research, 2023, Volume: 41, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Flavonoids; Glial Cell Line-Derived Neurotrophic Factor; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Neurotoxicity Syndromes; Parkinson Disease; Rutin	2023
Aminochrome decreases NGF, GDNF and induces neuroinflammation in organotypic midbrain slice cultures. Neurotoxicology, 2018, Volume: 66 Topics: Animals; Encephalitis; Glial Cell Line-Derived Neurotrophic Factor; Indolequinones; Interleukin-1beta; Mesencephalon; Microglia; Nerve Growth Factor; Parkinson Disease; Rats, Wistar; Tissue Culture Techniques; Tumor Necrosis Factor-alpha; Tyrosine 3-Monooxygenase	2018
Direct intranigral injection of dopaminochrome causes degeneration of dopamine neurons. Neuroscience letters, 2016, Jan-26, Volume: 612 Topics: 1-Methyl-4-phenylpyridinium; Animals; Disease Models, Animal; Dopaminergic Neurons; Indolequinones; Male; Nerve Degeneration; Parkinson Disease; Pars Compacta; Rats, Sprague-Dawley	2016
Aminochrome induces dopaminergic neuronal dysfunction: a new animal model for Parkinson's disease. Cellular and molecular life sciences : CMLS, 2016, Volume: 73, Issue:18 Topics: Adenosine Triphosphate; Animals; Behavior, Animal; Chromatography, High Pressure Liquid; Corpus Striatum; Disease Models, Animal; Dopamine; Dopaminergic Neurons; gamma-Aminobutyric Acid; Humans; Indolequinones; Male; Mitochondria; Oxygen Consumption; Parkinson Disease; Rats; Rats, Sprague-Dawley; Substantia Nigra; Synaptic Vesicles; Tyrosine 3-Monooxygenase	2016
Dopamine (DA) induced irreversible proteasome inhibition via DA derived quinones. Free radical research, 2009, Volume: 43, Issue:4 Topics: Animals; Arachidonic Acid; Catalase; Cell Line; Chymotrypsin; Dopamine; Glutathione; Humans; Hydrogen Peroxide; Indolequinones; Kinetics; Leupeptins; Mice; Oxidative Stress; Parkinson Disease; Protease Inhibitors; Proteasome Inhibitors; Superoxide Dismutase; Vitamin E	2009
Molecular and neurochemical mechanisms in PD pathogenesis. Neurotoxicity research, 2009, Volume: 16, Issue:3 Topics: Animals; Cell Death; Dopamine; FMN Reductase; Humans; Indolequinones; Intermediate Filament Proteins; Models, Biological; Nerve Degeneration; Neurochemistry; Neurotoxins; Parkinson Disease	2009
Overexpression of VMAT-2 and DT-diaphorase protects substantia nigra-derived cells against aminochrome neurotoxicity. Biochimica et biophysica acta, 2012, Volume: 1822, Issue:7 Topics: Analysis of Variance; Animals; Cell Death; Cell Line; DNA; Dopamine; Humans; Indolequinones; Lobeline; Microscopy, Confocal; Microscopy, Electron, Transmission; Mitochondria; NAD(P)H Dehydrogenase (Quinone); Neurons; Oxidation-Reduction; Oxidative Stress; Parkinson Disease; Rats; Rats, Inbred F344; Reserpine; Substantia Nigra; Transfection; Vesicular Monoamine Transport Proteins	2012
Protective effects of nicotine against aminochrome-induced toxicity in substantia nigra derived cells: implications for Parkinson's disease. Neurotoxicity research, 2012, Volume: 22, Issue:2 Topics: Animals; Cell Line; Dicumarol; Dopaminergic Neurons; Dose-Response Relationship, Drug; Indolequinones; Mecamylamine; Melanins; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Parkinson Disease; Rats; Receptors, Nicotinic; Substantia Nigra; Uncoupling Agents	2012
Increased dopamine peroxidation in postmortem Parkinsonian brain. Biochimica et biophysica acta, 2002, Oct-10, Volume: 1573, Issue:1 Topics: Aged; Aged, 80 and over; Basal Ganglia; Brain; Chromatography, High Pressure Liquid; Dopamine; Female; Hot Temperature; Humans; Hydrogen Peroxide; Indolequinones; Indoles; Male; Mesencephalon; Middle Aged; Oxidation-Reduction; Parkinson Disease; Postmortem Changes	2002
Dopamine-derived dopaminochrome promotes H(2)O(2) release at mitochondrial complex I: stimulation by rotenone, control by Ca(2+), and relevance to Parkinson disease. The Journal of biological chemistry, 2005, Apr-22, Volume: 280, Issue:16 Topics: Animals; Brain; Cysteinyldopa; Electron Transport Complex I; Hydrogen Peroxide; Indolequinones; Mitochondria; Parkinson Disease; Rats	2005
Reversible inhibition of alpha-synuclein fibrillization by dopaminochrome-mediated conformational alterations. The Journal of biological chemistry, 2005, Jun-03, Volume: 280, Issue:22 Topics: alpha-Synuclein; Amino Acid Motifs; Circular Dichroism; DNA, Complementary; Dopamine; Histidine; Humans; Indolequinones; Methionine; Microscopy, Atomic Force; Microscopy, Electron; Mutagenesis; Mutation; Nerve Tissue Proteins; Oxidative Stress; Oxygen; Parkinson Disease; Peptides; Protein Conformation; Protein Structure, Secondary; Recombinant Proteins; Spectroscopy, Fourier Transform Infrared; Synucleins; Time Factors; Tyrosine	2005
Copper neurotoxicity is dependent on dopamine-mediated copper uptake and one-electron reduction of aminochrome in a rat substantia nigra neuronal cell line. Journal of neurochemistry, 2001, Volume: 77, Issue:2 Topics: Animals; Catalase; Cell Line; Copper Sulfate; Dicumarol; Dopamine; Electron Spin Resonance Spectroscopy; Enzyme Induction; Glutathione Peroxidase; Indolequinones; Indoles; Ion Transport; Metallothionein; NAD(P)H Dehydrogenase (Quinone); Neurons; Nomifensine; Oxidation-Reduction; Oxidative Stress; Parkinson Disease; Rats; RNA, Messenger; Substantia Nigra; Superoxide Dismutase	2001