aminocaproic acid has been researched along with Stomach Ulcer in 15 studies
Aminocaproic Acid: An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
6-aminohexanoic acid : An epsilon-amino acid comprising hexanoic acid carrying an amino substituent at position C-6. Used to control postoperative bleeding, and to treat overdose effects of the thrombolytic agents streptokinase and tissue plasminogen activator.
Stomach Ulcer: Ulceration of the GASTRIC MUCOSA due to contact with GASTRIC JUICE. It is often associated with HELICOBACTER PYLORI infection or consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "9% for indomethacin-induced acute gastric ulcer (IAGU) rats, respectively] than those of ZAC alone due to the significantly slower renal clearance (CL(R))." | 7.77 | Pharmacokinetic interaction between ϵ-acetamidocaproic acid (AACA) and cimetidine in indomethacin-induced acute gastric ulcer and control rats: inhibition of active renal secretion of AACA by cimetidine. ( Choi, YH; Kim, YG; Lee, M; Lee, MG; Lee, U; Oh, E; Suh, JH, 2011) |
| "The pharmacokinetics of ϵ-acetamidocaproic acid (AACA) were evaluated after the intravenous and oral administration of an antiulcer agent, zinc acexamate (ZAC) at a dose of 20 mg kg⁻¹ (ion pairing between zinc and AACA) in rats with indomethacin-induced acute gastric ulcer (IAGU) or indomethacin-induced small bowel inflammation (ISBI)." | 3.78 | ε-Acetamidocaproic acid pharmacokinetics in rats with gastric ulcer or small bowel inflammation. ( Choi, YH; Kim, YG; Lee, BK; Lee, MG; Lee, U; Oh, E, 2012) |
| "9% for indomethacin-induced acute gastric ulcer (IAGU) rats, respectively] than those of ZAC alone due to the significantly slower renal clearance (CL(R))." | 3.77 | Pharmacokinetic interaction between ϵ-acetamidocaproic acid (AACA) and cimetidine in indomethacin-induced acute gastric ulcer and control rats: inhibition of active renal secretion of AACA by cimetidine. ( Choi, YH; Kim, YG; Lee, M; Lee, MG; Lee, U; Oh, E; Suh, JH, 2011) |
| "The antiulcerogenic effect of zinc acexamate on gastric ulcers induced by reserpine and changes in the morphology of gastric mucosa were studied in rats by histochemical methods." | 3.68 | Protective effect of zinc acexamate on experimental gastric ulcers: a histochemical study. ( Barbarino, F; Brilinschi, C; Toganel, E, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (40.00) | 18.7374 |
| 1990's | 6 (40.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (13.33) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Ding, Y | 1 |
| Meng, R | 1 |
| Yin, H | 1 |
| Hou, Z | 1 |
| Sun, C | 1 |
| Liu, W | 1 |
| Hao, S | 1 |
| Pan, Y | 1 |
| Wang, B | 1 |
| Choi, YH | 2 |
| Lee, U | 2 |
| Suh, JH | 1 |
| Kim, YG | 2 |
| Lee, M | 1 |
| Oh, E | 2 |
| Lee, MG | 2 |
| Lee, BK | 1 |
| Navarro, C | 7 |
| Bravo, ML | 2 |
| Carulla, C | 1 |
| Bulbena, O | 8 |
| Lapenna, D | 1 |
| Cuccurullo, F | 1 |
| Bravo, L | 2 |
| Barbarino, F | 1 |
| Toganel, E | 1 |
| Brilinschi, C | 1 |
| Escolar, G | 6 |
| Fontarnau, R | 1 |
| Jiménez, E | 1 |
| Galmés, JL | 1 |
| Casanovas, LI | 1 |
| Pérez Mota, A | 1 |
| Pérez Muñoz, C | 1 |
| Casanova Cánovas, A | 1 |
| Pérez Fernández, E | 1 |
| Pfeiffer, CJ | 1 |
| Esplugues, JV | 2 |
| Esplugues, J | 2 |
| Camarasa, J | 1 |
| Vernetta, C | 1 |
| Pavlovskiĭ, DP | 1 |
| Shuliarenko, VA | 1 |
| Ovsianko, IuI | 1 |
| Martí-Bonmatí, E | 1 |
1 trial available for aminocaproic acid and Stomach Ulcer
| Article | Year |
|---|---|
[Acute and prophylactic treatment of peptic ulcer with zinc acexamate or cimetidine].
Topics: Aminocaproates; Aminocaproic Acid; Cimetidine; Clinical Trials as Topic; Duodenal Ulcer; Humans; Ran | 1986 |
14 other studies available for aminocaproic acid and Stomach Ulcer
| Article | Year |
|---|---|
Keratin-A6ACA NPs for gastric ulcer diagnosis and repair.
Topics: Aminocaproic Acid; Animals; Cytoskeleton; Endoscopy; Female; Fluorescent Dyes; Gastric Juice; Hair; | 2021 |
Pharmacokinetic interaction between ϵ-acetamidocaproic acid (AACA) and cimetidine in indomethacin-induced acute gastric ulcer and control rats: inhibition of active renal secretion of AACA by cimetidine.
Topics: Administration, Oral; Aminocaproates; Aminocaproic Acid; Animals; Anti-Ulcer Agents; Blood Proteins; | 2011 |
ε-Acetamidocaproic acid pharmacokinetics in rats with gastric ulcer or small bowel inflammation.
Topics: Administration, Oral; Aminocaproates; Aminocaproic Acid; Animals; Anti-Ulcer Agents; Arteries; Blood | 2012 |
Gastrotoxic activity and inhibitory effects on gastric mucosal PGE2 production with different non-steroidal anti-inflammatory drugs: modifications induced by pretreatment with zinc acexamate.
Topics: Aminocaproates; Aminocaproic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agen | 1994 |
Gastroprotective effect of zinc.
Topics: Aminocaproates; Aminocaproic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agen | 1994 |
[Protection by zinc acexamate against gastric lesions induced by non-steroid anti-inflammatory agents].
Topics: Aminocaproates; Aminocaproic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agen | 1993 |
Protective effect of zinc acexamate on experimental gastric ulcers: a histochemical study.
Topics: Adenosine Triphosphatases; Aminocaproates; Aminocaproic Acid; Animals; Anti-Ulcer Agents; Energy Met | 1992 |
Effect of zinc acexamate on gastric lesions induced by aspirin: a morphological study.
Topics: Aminocaproates; Aminocaproic Acid; Animals; Anti-Ulcer Agents; Aspirin; Carrageenan; Chromatography, | 1990 |
Effect of zinc acexamate and ranitidine on chronic gastric lesions in the rat.
Topics: Acetates; Acetic Acid; Aminocaproates; Aminocaproic Acid; Animals; Anti-Ulcer Agents; Male; Ranitidi | 1990 |
Zinc acexamate reduces gastric damage induced by platelet-activating factor.
Topics: Aminocaproates; Aminocaproic Acid; Animals; Blood Pressure; Gastric Mucosa; Male; Mast Cells; Platel | 1989 |
Anti-ulcer and membrane stabilizing actions of zinc acexamate.
Topics: Aminocaproates; Aminocaproic Acid; Animals; Anti-Ulcer Agents; Antifibrinolytic Agents; Cell Membran | 1987 |
Antiulcerogenic activity of zinc acexamate in different experimental models.
Topics: Aminocaproates; Aminocaproic Acid; Animals; Bile Acids and Salts; Disease Models, Animal; Female; Ma | 1987 |
[Treatment of profuse gastroduodenal hemorrhages in peptic ulcer and myocardial infarction].
Topics: Aged; Aminocaproic Acid; Blood Transfusion; Critical Care; Duodenal Ulcer; Evaluation Studies as Top | 1985 |
Effects of zinc acexamate on gastric mucosal resistance factors.
Topics: Aminocaproates; Aminocaproic Acid; Animals; Female; Gastric Mucosa; Mucus; Necrosis; Rats; Rats, Inb | 1985 |