Page last updated: 2024-10-17

aminocaproic acid and Shock

aminocaproic acid has been researched along with Shock in 8 studies

Aminocaproic Acid: An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
6-aminohexanoic acid : An epsilon-amino acid comprising hexanoic acid carrying an amino substituent at position C-6. Used to control postoperative bleeding, and to treat overdose effects of the thrombolytic agents streptokinase and tissue plasminogen activator.

Shock: A pathological condition manifested by failure to perfuse or oxygenate vital organs.

Research Excerpts

ExcerptRelevanceReference
" A combination of aprotinin with tranexamic acid may be effective in preventing or delaying rebleeding after rupture of an intracerebral aneurysm; the addition of aprotinin seems to decrease the incidence of delayed cerebral vasospasm and ischaemic complications which are sometimes noted when tranexamic acid alone is used."4.77Clinical application of inhibitors of fibrinolysis. ( Verstraete, M, 1985)
"The rate of neonatal intracranial hemorrhage was not significantly different between the 2 groups (P =."1.32Impact of AMICAR on hemorrhagic complications of ECMO: a ten-year review. ( Arnold, JH; Betit, P; Chang, RW; Downard, CD; Garza, JJ; Wilson, JM, 2003)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19905 (62.50)18.7374
1990's0 (0.00)18.2507
2000's2 (25.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lieberman, BL1
Kennedy, MK1
Lorenzo, DR1
Reed, LJ1
Adamo, AK1
Cardo, VA1
Badner, VM1
Downard, CD1
Betit, P1
Chang, RW1
Garza, JJ1
Arnold, JH1
Wilson, JM1
SPINK, WW2
CHARTRAND, S2
DAVIS, R1
KUROZAWA, T1
DAVIS, RB1
POTTER, R1
Martínez Rodríguez, E1
Mato, M1
Otero, J1
Ferri, JR1
Gonzálvez, A1
Torres, LM1
Verstraete, M1
Bottari, M1
Donati, L1
Gagnatelli, G1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy in Controlling Bleeding Post-coronary Bypass Surgery Using Combination of Local Application of Tranexamic Acid and Intravenous Tranexamic Compared to Intravenous Tranexamic Acid Alone. A Randomized Controlled Trial[NCT01600599]40 participants (Actual)Interventional2011-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for aminocaproic acid and Shock

ArticleYear
Clinical application of inhibitors of fibrinolysis.
    Drugs, 1985, Volume: 29, Issue:3

    Topics: 4-Aminobenzoic Acid; Aminocaproic Acid; Angioedema; Antifibrinolytic Agents; Aprotinin; Blood Preser

1985

Other Studies

7 other studies available for aminocaproic acid and Shock

ArticleYear
Control of life-threatening head and neck hemorrhage after dental extractions: a case report.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2010, Volume: 68, Issue:9

    Topics: Aminocaproic Acid; Blood Transfusion; Deamino Arginine Vasopressin; Edema; Factor VII Deficiency; Fa

2010
Impact of AMICAR on hemorrhagic complications of ECMO: a ten-year review.
    Journal of pediatric surgery, 2003, Volume: 38, Issue:8

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Child; Child, Preschool; Extracorporeal Membrane

2003
CANINE ENDOTOXIN SHOCK: PROTECTION AGAINST A LETHAL DOSE OF ENDOTOXIN FOLLOWING AN INFUSION OF HISTAMINE.
    Nature, 1963, Nov-02, Volume: 200

    Topics: Aminocaproates; Aminocaproic Acid; Animals; Dogs; Endotoxins; Histamine; Hydrocortisone; Infusions,

1963
[CASE OF TREATMENT OF EPISTAXIS WITH IPSILON CAUSING SUDDEN SYMPTOMS OF SHOCK].
    Jibi inkoka Otolaryngology, 1963, Volume: 35

    Topics: Adolescent; Aminocaproates; Aminocaproic Acid; Drug Hypersensitivity; Epistaxis; Shock; Shock, Septi

1963
THE INITIAL STAGE OF CANINE ENDOTOXIN SHOCK AS AN EXPRESSION OF ANAPHYLACTIC SHOCK: STUDIES ON COMPLEMENT TITERS AND PLASMA HISTAMINE CONCENTRATIONS.
    The Journal of clinical investigation, 1964, Volume: 43

    Topics: Aminocaproates; Aminocaproic Acid; Anaphylaxis; Animals; Blood; Blood Pressure; Complement System Pr

1964
[Hemostatic drugs in a patient with antiphospholipid syndrome and clinically significant perioperative bleeding].
    Revista espanola de anestesiologia y reanimacion, 2006, Volume: 53, Issue:3

    Topics: Adult; Aminocaproic Acid; Antiphospholipid Syndrome; Aprotinin; Blood Coagulation Tests; Blood Loss,

2006
[Disseminated intravascular coagulation as a complication of shock].
    Atti della Accademia medica lombarda, 1973, Volume: 28, Issue:1-4

    Topics: Aminocaproic Acid; Aprotinin; Disseminated Intravascular Coagulation; Heparin; Humans; Shock; Tranex

1973