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aminocaproic acid and Schwartzman Phenomenon

aminocaproic acid has been researched along with Schwartzman Phenomenon in 6 studies

Aminocaproic Acid: An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
6-aminohexanoic acid : An epsilon-amino acid comprising hexanoic acid carrying an amino substituent at position C-6. Used to control postoperative bleeding, and to treat overdose effects of the thrombolytic agents streptokinase and tissue plasminogen activator.

Research Excerpts

ExcerptRelevanceReference
" Thrombin, at a dosage producing a fibrinogen consumption of 70% within 4 h (1 unit/kg/min), failed to produce extrapulmonary microthrombi unless fibrinolysis inhibition (epsilon-aminocaproic acid-EACA) or alpha-adrenergic stimulation (norepinephrine) were provided simultaneously."5.27Vasoactive agents and production of thrombosis during intravascular coagulation 1--comparative effects of norepinephrine in thrombin and adenosine diphosphate (ADP) treated rabbits. ( Daoust-Fiorilli, J; Latour, JG; Léger-Gauthier, C, 1984)
" Thrombin, at a dosage producing a fibrinogen consumption of 70% within 4 h (1 unit/kg/min), failed to produce extrapulmonary microthrombi unless fibrinolysis inhibition (epsilon-aminocaproic acid-EACA) or alpha-adrenergic stimulation (norepinephrine) were provided simultaneously."1.27Vasoactive agents and production of thrombosis during intravascular coagulation 1--comparative effects of norepinephrine in thrombin and adenosine diphosphate (ADP) treated rabbits. ( Daoust-Fiorilli, J; Latour, JG; Léger-Gauthier, C, 1984)
"A fibrin slide test was utilized to study cutaneous vascular plasminogen activator activity in normal rabbit, rat, monkey, and human skin and in rabbit skin following development of the local Shwartzman reaction and after substituting epsilon-aminocaproic acid for the preparatory injection of endotoxin in the local Shwartzman reaction."1.26Cutaneous vascular fibrinolytic activity in the local Shwartzman reaction. ( Bergstein, JM, 1977)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19906 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
RAMOS, AO1
CHAPMAN, LF1
CORRADO, AP1
FORTES, VA1
FIORILLO, AM1
BERTELLI, A1
BONMASSAR, E1
GENOVESE, E1
LAMI, V1
ROSSANO, MA1
TRABUCCHI, E1
MCFADDEN, SW1
MARGARETTEN, W1
ELTING, J1
ROTHENBERG, J1
MCKAY, DG1
Latour, JG1
Léger-Gauthier, C1
Daoust-Fiorilli, J1
Bergstein, JM1

Other Studies

6 other studies available for aminocaproic acid and Schwartzman Phenomenon

ArticleYear
Inhibition of the local Shwartzman phenomenon by the administration of epsilon amino caproic acid.
    Archives internationales de pharmacodynamie et de therapie, 1961, Jul-01, Volume: 132

    Topics: Amino Acids; Aminocaproic Acid; Antifibrinolytic Agents; Caproates; Hemorrhage; Humans; Shwartzman P

1961
[STUDY ON SKIN HOMOGRAFTS IN RATS TREATED WITH THE ACETYL DERIVATIVE OF EPSILON-AMINOCAPROIC ACID].
    Archives internationales de pharmacodynamie et de therapie, 1964, Nov-01, Volume: 152

    Topics: Allografts; Aminocaproates; Aminocaproic Acid; Pharmacology; Rats; Research; Shwartzman Phenomenon;

1964
[ON THE ACTION OF EPSILON-AMINOCAPROIC ACID ON SOME ALLERGIC AND IMMUNOLOGIC PHENOMENA].
    Dermatologica, 1965, Volume: 130

    Topics: Aminocaproates; Aminocaproic Acid; Anaphylaxis; Animals; Female; Guinea Pigs; Humans; Hypersensitivi

1965
EXPERIMENTAL ADRENAL HEMORRHAGE IN THE GENERALIZED SHWARTZMAN REACTION.
    Laboratory investigation; a journal of technical methods and pathology, 1965, Volume: 14

    Topics: Adrenal Gland Diseases; Adrenocorticotropic Hormone; Aminocaproates; Aminocaproic Acid; Hemorrhage;

1965
Vasoactive agents and production of thrombosis during intravascular coagulation 1--comparative effects of norepinephrine in thrombin and adenosine diphosphate (ADP) treated rabbits.
    Pathology, 1984, Volume: 16, Issue:4

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aminocaproic Acid; Animals; Aspirin; Blood Coagulatio

1984
Cutaneous vascular fibrinolytic activity in the local Shwartzman reaction.
    The American journal of pathology, 1977, Volume: 88, Issue:3

    Topics: Aminocaproic Acid; Animals; Blood Vessels; Female; Fibrin; Fibrinolysis; Haplorhini; Humans; In Vitr

1977