Page last updated: 2024-10-17

aminocaproic acid and Phlegmasia Alba Dolens

aminocaproic acid has been researched along with Phlegmasia Alba Dolens in 12 studies

Aminocaproic Acid: An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
6-aminohexanoic acid : An epsilon-amino acid comprising hexanoic acid carrying an amino substituent at position C-6. Used to control postoperative bleeding, and to treat overdose effects of the thrombolytic agents streptokinase and tissue plasminogen activator.

Phlegmasia Alba Dolens: Inflammation that is characterized by swollen, pale, and painful limb. It is usually caused by DEEP VEIN THROMBOSIS in a FEMORAL VEIN, following PARTURITION or an illness. This condition is also called milk leg or white leg.

Research Excerpts

ExcerptRelevanceReference
" A combination of aprotinin with tranexamic acid may be effective in preventing or delaying rebleeding after rupture of an intracerebral aneurysm; the addition of aprotinin seems to decrease the incidence of delayed cerebral vasospasm and ischaemic complications which are sometimes noted when tranexamic acid alone is used."4.77Clinical application of inhibitors of fibrinolysis. ( Verstraete, M, 1985)
"One hundred consecutive patients treated with epsilon aminocaproic acid 24 grams daily prior to surgery for ruptured intracranial aneurysms have been compared with the previous 100 patients managed similarly but without anti-fibrinolytic drugs."3.66Anti-fibrinolytic treatment in the pre-operative management of subarachnoid haemorrhage caused by ruptured intracranial aneurysm. ( Ameen, AA; Illingworth, R, 1981)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-199011 (91.67)18.7374
1990's0 (0.00)18.2507
2000's1 (8.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
HALLER, JA1
MAYS, T1
NORDOEY, A1
KOLLER, F1
BROWSE, NL1
JAMES, DC1
DOUGLAS, AS2
MCNICOL, GP2
Martínez Rodríguez, E1
Mato, M1
Otero, J1
Ferri, JR1
Gonzálvez, A1
Torres, LM1
Moser, KM1
Ameen, AA1
Illingworth, R1
MacIomhair, M1
Lavelle, SM1
Sinclair, J1
Forbes, CD1
Prentice, CR1
Scott, R1
Verstraete, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy in Controlling Bleeding Post-coronary Bypass Surgery Using Combination of Local Application of Tranexamic Acid and Intravenous Tranexamic Compared to Intravenous Tranexamic Acid Alone. A Randomized Controlled Trial[NCT01600599]40 participants (Actual)Interventional2011-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for aminocaproic acid and Phlegmasia Alba Dolens

ArticleYear
THROMBOLYTIC THERAPY.
    British medical bulletin, 1964, Volume: 20

    Topics: Aminocaproates; Aminocaproic Acid; Anticoagulants; Biomedical Research; Deoxyribonuclease I; Drug Th

1964
[THROMBOLYTIC THERAPY AND CHANGES IN FIBRINOLYTIC ACTIVITY].
    Recenti progressi in medicina, 1964, Volume: 37

    Topics: Aminocaproates; Aminocaproic Acid; Anticoagulants; Deoxyribonuclease I; Fibrinolysin; Fibrinolysis;

1964
Thromboembolic disease in the patient undergoing urologic surgery.
    The Urologic clinics of North America, 1983, Volume: 10, Issue:1

    Topics: Aminocaproic Acid; Anticoagulants; Clothing; Dextrans; Heparin; Humans; Postoperative Complications;

1983
Clinical application of inhibitors of fibrinolysis.
    Drugs, 1985, Volume: 29, Issue:3

    Topics: 4-Aminobenzoic Acid; Aminocaproic Acid; Angioedema; Antifibrinolytic Agents; Aprotinin; Blood Preser

1985

Trials

1 trial available for aminocaproic acid and Phlegmasia Alba Dolens

ArticleYear
The incidence of deep vein thrombosis in prostatectomised patients following the administration of the fibrinolytic inhibitor, aminocaproic acid (EACA).
    Urological research, 1976, Nov-10, Volume: 4, Issue:3

    Topics: Aged; Aminocaproates; Aminocaproic Acid; Antifibrinolytic Agents; Clinical Trials as Topic; Humans;

1976

Other Studies

7 other studies available for aminocaproic acid and Phlegmasia Alba Dolens

ArticleYear
EXPERIMENTAL STUDIES ON ILIOFEMORAL VENOUS THROMBOSIS.
    The American surgeon, 1963, Volume: 29

    Topics: Aminocaproates; Aminocaproic Acid; Animals; Dogs; Femoral Vein; Fibrinolysis; Iliac Vein; Lymphedema

1963
EXPERIMENTAL VENOUS THROMBOSIS IN RATS. INCREASED FORMATION DURING INHIBITION OF THE FIBRINOLYTIC SYSTEM WITH EPSILON AMINO CAPROIC ACID.
    Thrombosis et diathesis haemorrhagica, 1963, Jul-15, Volume: 143

    Topics: Aminocaproates; Aminocaproic Acid; Caproates; Fibrinolysis; Rats; Research; Thrombophlebitis; Thromb

1963
[ON THE THERAPY OF POSTOPERATIVE HEMORRHAGE AND THROMBOSIS FOLLOWING PROSTATECTOMY WITH SPECIAL REFERENCE TO 6-AMINOCAPROIC ACID].
    Helvetica chirurgica acta, 1963, Volume: 30

    Topics: Aminocaproates; Aminocaproic Acid; Anticoagulants; Hematuria; Hemorrhage; Humans; Male; Postoperativ

1963
STREPTOKINASE AND PULMONARY EMBOLISM.
    Lancet (London, England), 1964, Nov-14, Volume: 2, Issue:7368

    Topics: Aminocaproates; Aminocaproic Acid; Biomedical Research; Blood Coagulation Tests; Deoxyribonuclease I

1964
[Hemostatic drugs in a patient with antiphospholipid syndrome and clinically significant perioperative bleeding].
    Revista espanola de anestesiologia y reanimacion, 2006, Volume: 53, Issue:3

    Topics: Adult; Aminocaproic Acid; Antiphospholipid Syndrome; Aprotinin; Blood Coagulation Tests; Blood Loss,

2006
Anti-fibrinolytic treatment in the pre-operative management of subarachnoid haemorrhage caused by ruptured intracranial aneurysm.
    Journal of neurology, neurosurgery, and psychiatry, 1981, Volume: 44, Issue:3

    Topics: Adolescent; Adult; Aged; Aminocaproates; Aminocaproic Acid; Antifibrinolytic Agents; Child; Female;

1981
Thrombus weight as a measure of hypercoagulability induced by drugs.
    Thrombosis and haemostasis, 1979, Oct-31, Volume: 42, Issue:3

    Topics: Adenosine Diphosphate; Aging; Aminocaproates; Aminocaproic Acid; Animals; Benzopyrans; Blood Coagula

1979