aminocaproic acid has been researched along with Neoplasms in 16 studies
Aminocaproic Acid: An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
6-aminohexanoic acid : An epsilon-amino acid comprising hexanoic acid carrying an amino substituent at position C-6. Used to control postoperative bleeding, and to treat overdose effects of the thrombolytic agents streptokinase and tissue plasminogen activator.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sixty-nine adults with malignancy scheduled for either pelvic, extremity or spine surgery during general anesthesia entered this randomized, double-blind, placebo-controlled trial, and received either intravenous aprotinin (n = 23), bolus of 2 x 10(6) kallikrein inactivator units (KIU), followed by an infusion of 5 x 10(5) KIU/h, or EACA (n = 22), bolus of 150 mg/kg, followed by a 15 mg/kg/h infusion or saline placebo (n = 24) during surgery." | 2.71 | Antifibrinolytic therapy and perioperative blood loss in cancer patients undergoing major orthopedic surgery. ( Amar, D; Boland, PJ; Grant, FM; Healey, JA; Leung, DH; Zhang, H, 2003) |
| " Secondary outcomes were other adverse events, blood transfusion, and blood loss." | 2.55 | The Safety and Efficacy of Lysine Analogues in Cancer Patients: A Systematic Review and Meta-Analysis. ( Breau, RH; Cagiannos, I; Cnossen, S; Fergusson, DA; Fergusson, NA; Hutton, B; Lavallée, LT; Montroy, J; Morash, C, 2017) |
| "Hexamethylene bisacetamide (HMBA) is a potent in vitro differentiating agent that has clinical potential as an anticancer drug both as a single agent and as a component of combination therapy." | 1.29 | Simultaneous measurement of the cell-differentiating agent hexamethylene bisacetamide and its metabolites by gas chromatography. ( Chun, HG; Kelley, JA; Roth, JS; Ward, FT, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (31.25) | 18.7374 |
| 1990's | 2 (12.50) | 18.2507 |
| 2000's | 3 (18.75) | 29.6817 |
| 2010's | 4 (25.00) | 24.3611 |
| 2020's | 2 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Diamandis, P | 1 |
| Wildenhain, J | 1 |
| Clarke, ID | 1 |
| Sacher, AG | 1 |
| Graham, J | 1 |
| Bellows, DS | 1 |
| Ling, EK | 1 |
| Ward, RJ | 1 |
| Jamieson, LG | 1 |
| Tyers, M | 1 |
| Dirks, PB | 1 |
| Lin, R | 1 |
| Elf, S | 1 |
| Shan, C | 1 |
| Kang, HB | 1 |
| Ji, Q | 1 |
| Zhou, L | 1 |
| Hitosugi, T | 1 |
| Zhang, L | 1 |
| Zhang, S | 1 |
| Seo, JH | 1 |
| Xie, J | 1 |
| Tucker, M | 1 |
| Gu, TL | 1 |
| Sudderth, J | 1 |
| Jiang, L | 1 |
| Mitsche, M | 1 |
| DeBerardinis, RJ | 1 |
| Wu, S | 1 |
| Li, Y | 1 |
| Mao, H | 1 |
| Chen, PR | 1 |
| Wang, D | 1 |
| Chen, GZ | 1 |
| Hurwitz, SJ | 1 |
| Lonial, S | 1 |
| Arellano, ML | 1 |
| Khoury, HJ | 1 |
| Khuri, FR | 1 |
| Lee, BH | 1 |
| Lei, Q | 1 |
| Brat, DJ | 1 |
| Ye, K | 1 |
| Boggon, TJ | 1 |
| He, C | 1 |
| Kang, S | 1 |
| Fan, J | 1 |
| Chen, J | 1 |
| Hu, Q | 1 |
| Wang, K | 1 |
| Qiu, L | 1 |
| Montroy, J | 2 |
| Hutton, B | 2 |
| Fergusson, DA | 2 |
| Tinmouth, A | 1 |
| Lavallée, LT | 2 |
| Cagiannos, I | 2 |
| Morash, C | 2 |
| Flaman, A | 1 |
| Breau, RH | 2 |
| Fergusson, NA | 1 |
| Cnossen, S | 1 |
| Chen, CY | 1 |
| Kim, TH | 1 |
| Wu, WC | 1 |
| Huang, CM | 1 |
| Wei, H | 1 |
| Mount, CW | 1 |
| Tian, Y | 1 |
| Jang, SH | 1 |
| Pun, SH | 1 |
| Jen, AK | 1 |
| Bouziotis, P | 1 |
| Gourni, E | 1 |
| Patsis, G | 1 |
| Psimadas, D | 1 |
| Zikos, C | 1 |
| Fani, M | 1 |
| Xanthopoulos, S | 1 |
| Loudos, G | 1 |
| Paravatou-Petsotas, M | 1 |
| Livaniou, E | 1 |
| Varvarigou, AD | 1 |
| Pirmettis, I | 1 |
| Papadopoulos, M | 1 |
| Amar, D | 1 |
| Grant, FM | 1 |
| Zhang, H | 1 |
| Boland, PJ | 1 |
| Leung, DH | 1 |
| Healey, JA | 1 |
| GIORDANI, R | 1 |
| BEEHINI, MF | 1 |
| RICCIONI, N | 1 |
| GLAGNONI, P | 1 |
| KINJO, K | 1 |
| HIRATA, T | 1 |
| OKAMOTO, S | 1 |
| ATCHLEY, WA | 1 |
| BHAGAVAN, NV | 1 |
| CLIFFTON, EE | 1 |
| AGOSTINO, D | 1 |
| LAGARDE, C | 1 |
| HUGUES, A | 1 |
| CHAUVERGNE, J | 1 |
| LACHAPELE, AP | 1 |
| Jung, KH | 1 |
| Song, SH | 1 |
| Paik, JY | 1 |
| Koh, BH | 1 |
| Choe, YS | 1 |
| Lee, EJ | 1 |
| Kim, BT | 1 |
| Lee, KH | 1 |
| Roth, JS | 1 |
| Kelley, JA | 1 |
| Chun, HG | 1 |
| Ward, FT | 1 |
| Benson, K | 1 |
| Fields, K | 1 |
| Hiemenz, J | 1 |
| Zorsky, P | 1 |
| Ballester, O | 1 |
| Perkins, J | 1 |
| Elfenbein, G | 1 |
3 reviews available for aminocaproic acid and Neoplasms
| Article | Year |
|---|---|
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms; | 2015 |
The Safety and Efficacy of Lysine Analogues in Cancer Patients: A Systematic Review and Meta-Analysis.
Topics: Adult; Aminocaproic Acid; Blood Loss, Surgical; Blood Transfusion; Erythrocyte Transfusion; Humans; | 2017 |
The platelet-refractory bone marrow transplant patient: prophylaxis and treatment of bleeding.
Topics: Aminocaproic Acid; Blood Platelets; Bone Marrow Transplantation; Hemorrhage; Humans; Neoplasms; Plat | 1993 |
1 trial available for aminocaproic acid and Neoplasms
| Article | Year |
|---|---|
Antifibrinolytic therapy and perioperative blood loss in cancer patients undergoing major orthopedic surgery.
Topics: Aged; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Cell Count; Blood Loss, Surgical; | 2003 |
12 other studies available for aminocaproic acid and Neoplasms
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutic | 2007 |
6-Aminocaproic acid as a linker to improve near-infrared fluorescence imaging and photothermal cancer therapy of PEGylated indocyanine green.
Topics: Aminocaproic Acid; Animals; Cell Line, Tumor; Indocyanine Green; Mice; Neoplasms; Optical Imaging; P | 2021 |
Lysine analogue use during cancer surgery: a survey from a Canadian tertiary care centre.
Topics: Aminocaproic Acid; Blood Loss, Surgical; Humans; Lysine; Neoplasms; Ontario; Surveys and Questionnai | 2020 |
pH-dependent, thermosensitive polymeric nanocarriers for drug delivery to solid tumors.
Topics: Aminocaproic Acid; Animals; Cell Line, Tumor; Doxorubicin; Drug Carriers; Drug Delivery Systems; Hum | 2013 |
Radiochemical and radiobiological assessment of a pyridyl-S-cysteine functionalized bombesin derivative labeled with the (99m)Tc(CO)3(+) core.
Topics: Amino Acid Sequence; Aminocaproic Acid; Animals; Bombesin; Cell Line, Tumor; Cysteine; Humans; Mice; | 2013 |
[THE USE OF FIBRINOGEN-I 131 IN THE DIAGNOSIS OF TUMORS IN MAN].
Topics: Aminocaproates; Aminocaproic Acid; Fibrinogen; Humans; Iodine; Iodine Isotopes; Male; Neoplasms; Rad | 1963 |
STUDIES ON THE FIBRINOLYSIS IN TUMOR BEARING MICE. I. FIBRINOLYTIC SYSTEM, ASCITES RETENTION AND INTRAPERITONEAL HEMORRHAGE IN TUMOR BEARING MICE: SUPPRESSING EFFECT OF EPSILON AMINOCAPROIC ACID.
Topics: Aminocaproates; Aminocaproic Acid; Animals; Ascites; Carcinoma, Ehrlich Tumor; Fibrinolysis; Hemorrh | 1963 |
SALINE-SOLUBLE PREPARATIONS OF DEOXYRIBONUCLEOPROTEINS.
Topics: Acetates; Alanine; Aminobutyrates; Aminocaproates; Aminocaproic Acid; Animals; Cadmium; Caprylates; | 1964 |
THE EFFECTS OF FIBRIN FORMATION AND ALTERATIONS IN THE CLOTTING MECHANISM ON THE DEVELOPMENT OF METASTASES.
Topics: Aminocaproates; Aminocaproic Acid; Animals; Aprotinin; Blood Coagulation; Carcinoma 256, Walker; Car | 1965 |
[ANTI-CANCER CHEMOTHERAPY BY PROLONGED INTRA-ARTERIAL INFUSIONS].
Topics: Adrenal Cortex Hormones; Aminocaproates; Aminocaproic Acid; Anti-Bacterial Agents; Chemotherapy, Can | 1965 |
Direct targeting of tumor cell F(1)F(0) ATP-synthase by radioiodine angiostatin in vitro and in vivo.
Topics: Aminocaproic Acid; Angiostatins; Animals; Antibodies; Cell Line; Cell Line, Tumor; Endothelial Cells | 2007 |
Simultaneous measurement of the cell-differentiating agent hexamethylene bisacetamide and its metabolites by gas chromatography.
Topics: Acetamides; Aminocaproates; Aminocaproic Acid; Antineoplastic Agents; Chromatography, Gas; Diethyl P | 1994 |