Page last updated: 2024-10-17

aminocaproic acid and Melanoma

aminocaproic acid has been researched along with Melanoma in 4 studies

Aminocaproic Acid: An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
6-aminohexanoic acid : An epsilon-amino acid comprising hexanoic acid carrying an amino substituent at position C-6. Used to control postoperative bleeding, and to treat overdose effects of the thrombolytic agents streptokinase and tissue plasminogen activator.

Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)

Research Excerpts

ExcerptRelevanceReference
" pentoxifylline (Px) (which also were found to release PgI2 and t-PA) inhibited human tumor implant induced angiogenesis and reduced spontaneous metastases in 3 transplantable murine tumors (Furth-Columbia Wilms' tumor in Furth-Wistar rats, C-1300 neuroblastoma in A/J mice and HM-Kim mammary carcinoma in Wistar rats) but not in the NIH adenocarcinoma in Balb/c mice."3.68Studies on tumor induced angiogenesis. ( Ambrus, CM; Ambrus, JL; Forgach, P; Halpern, J; Niswander, P; Sayyid, S; Stadler, S; Toumbis, C, 1992)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's2 (50.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gavilondo, J1
PĂ©rez, R1
Mainardi, V1
Lage, A1
Khatib, AM1
Nip, J1
Fallavollita, L1
Lehmann, M1
Jensen, G1
Brodt, P1
Ambrus, JL1
Ambrus, CM1
Forgach, P1
Stadler, S1
Halpern, J1
Sayyid, S1
Niswander, P1
Toumbis, C1
Bos, R1
Berger, L1
Nieuwenhuizen, W1

Other Studies

4 other studies available for aminocaproic acid and Melanoma

ArticleYear
Effect of two antiproteinases on the growth of transplantable tumors and the proliferation of untransformed and transformed cells in culture.
    Neoplasma, 1982, Volume: 29, Issue:3

    Topics: Aminocaproates; Aminocaproic Acid; Animals; Aprotinin; Cell Line; In Vitro Techniques; Leukemia L121

1982
Regulation of urokinase plasminogen activator/plasmin-mediated invasion of melanoma cells by the integrin vitronectin receptor alphaVbeta3.
    International journal of cancer, 2001, Feb-01, Volume: 91, Issue:3

    Topics: Aminocaproic Acid; Aprotinin; Enzyme Activation; Enzyme Inhibitors; Humans; Isoenzymes; Melanoma; Ne

2001
Studies on tumor induced angiogenesis.
    EXS, 1992, Volume: 61

    Topics: Adenocarcinoma; Aminocaproic Acid; Animals; Cornea; Ditiocarb; Humans; Kidney Neoplasms; Macaca; Mam

1992
One-step purification of tissue-type plasminogen activator using affinity chromatography with a special monoclonal antibody under mild conditions.
    Biochimica et biophysica acta, 1992, Sep-15, Volume: 1117, Issue:2

    Topics: Aminocaproic Acid; Antibodies, Monoclonal; Chromatography, Affinity; Culture Media; Humans; Hydrogen

1992