aminocaproic acid has been researched along with Intraocular Pressure in 6 studies
Aminocaproic Acid: An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
6-aminohexanoic acid : An epsilon-amino acid comprising hexanoic acid carrying an amino substituent at position C-6. Used to control postoperative bleeding, and to treat overdose effects of the thrombolytic agents streptokinase and tissue plasminogen activator.
Intraocular Pressure: The pressure of the fluids in the eye.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine the safety and efficacy of topical aminocaproic acid (Caprogel) in the management of traumatic hyphema." | 9.10 | A phase III, multicenter, randomized, placebo-controlled clinical trial of topical aminocaproic acid (Caprogel) in the management of traumatic hyphema. ( Bradford, CA; Faulkner, A; Fekrat, S; Goldberg, MF; Juzych, M; McLeod, SD; Melia, M; Parker, JS; Pieramici, DJ; Rosen, R; Santander, SH, 2003) |
| "The purpose of this study is to determine the incidence of secondary hemorrhage after traumatic hyphema in children and to evaluate the efficacy of epsilon aminocaproic acid in reducing this incidence." | 9.08 | Clinical evaluation of aminocaproic acid for managing traumatic hyphema in children. ( Barsoum-Homsy, M; Brunette, I; Chevrette, L; Jacob, JL; Milot, J; Orquin, J; Polomeno, RC; Quigley, MG; Teboul, BK, 1995) |
| "Fifty-nine patients who sustained hyphema following blunt trauma were randomly assigned prospectively to either of two dose regimens of epsilon aminocaproic acid (Amicar)." | 9.06 | A comparison of two dose regimens of epsilon aminocaproic acid in the prevention and management of secondary traumatic hyphemas. ( Anderson, RJ; Fiscella, R; Frenkel, M; Goldberg, MF; Palmer, DJ, 1986) |
| "We treated five patients receiving epsilon-aminocaproic acid who demonstrated sudden and accelerated clot dissolution with accompanying increases in intraocular pressure 24 to 96 hours after discontinuing treatment." | 7.67 | Intraocular pressure increase associated with epsilon-aminocaproic acid therapy for traumatic hyphema. ( Dieste, MC; Frambach, DA; Hersh, PS; Kylstra, JA; Larrison, WI; Shingleton, BJ, 1988) |
| "To determine the safety and efficacy of topical aminocaproic acid (Caprogel) in the management of traumatic hyphema." | 5.10 | A phase III, multicenter, randomized, placebo-controlled clinical trial of topical aminocaproic acid (Caprogel) in the management of traumatic hyphema. ( Bradford, CA; Faulkner, A; Fekrat, S; Goldberg, MF; Juzych, M; McLeod, SD; Melia, M; Parker, JS; Pieramici, DJ; Rosen, R; Santander, SH, 2003) |
| "The purpose of this study is to determine the incidence of secondary hemorrhage after traumatic hyphema in children and to evaluate the efficacy of epsilon aminocaproic acid in reducing this incidence." | 5.08 | Clinical evaluation of aminocaproic acid for managing traumatic hyphema in children. ( Barsoum-Homsy, M; Brunette, I; Chevrette, L; Jacob, JL; Milot, J; Orquin, J; Polomeno, RC; Quigley, MG; Teboul, BK, 1995) |
| "Fifty-nine patients who sustained hyphema following blunt trauma were randomly assigned prospectively to either of two dose regimens of epsilon aminocaproic acid (Amicar)." | 5.06 | A comparison of two dose regimens of epsilon aminocaproic acid in the prevention and management of secondary traumatic hyphemas. ( Anderson, RJ; Fiscella, R; Frenkel, M; Goldberg, MF; Palmer, DJ, 1986) |
| "We treated five patients receiving epsilon-aminocaproic acid who demonstrated sudden and accelerated clot dissolution with accompanying increases in intraocular pressure 24 to 96 hours after discontinuing treatment." | 3.67 | Intraocular pressure increase associated with epsilon-aminocaproic acid therapy for traumatic hyphema. ( Dieste, MC; Frambach, DA; Hersh, PS; Kylstra, JA; Larrison, WI; Shingleton, BJ, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pieramici, DJ | 1 |
| Goldberg, MF | 2 |
| Melia, M | 1 |
| Fekrat, S | 1 |
| Bradford, CA | 1 |
| Faulkner, A | 1 |
| Juzych, M | 1 |
| Parker, JS | 1 |
| McLeod, SD | 1 |
| Rosen, R | 1 |
| Santander, SH | 1 |
| Wilker, SC | 1 |
| Singh, A | 1 |
| Ellis, FJ | 1 |
| Teboul, BK | 1 |
| Jacob, JL | 1 |
| Barsoum-Homsy, M | 1 |
| Brunette, I | 1 |
| Chevrette, L | 1 |
| Milot, J | 1 |
| Orquin, J | 1 |
| Polomeno, RC | 1 |
| Quigley, MG | 1 |
| Romano, PE | 1 |
| Dieste, MC | 1 |
| Hersh, PS | 1 |
| Kylstra, JA | 1 |
| Larrison, WI | 1 |
| Frambach, DA | 1 |
| Shingleton, BJ | 1 |
| Palmer, DJ | 1 |
| Frenkel, M | 1 |
| Fiscella, R | 1 |
| Anderson, RJ | 1 |
3 trials available for aminocaproic acid and Intraocular Pressure
| Article | Year |
|---|---|
A phase III, multicenter, randomized, placebo-controlled clinical trial of topical aminocaproic acid (Caprogel) in the management of traumatic hyphema.
Topics: Administration, Topical; Adolescent; Adult; Aged; Aminocaproic Acid; Anterior Chamber; Antifibrinoly | 2003 |
Clinical evaluation of aminocaproic acid for managing traumatic hyphema in children.
Topics: Administration, Oral; Aminocaproic Acid; Antifibrinolytic Agents; Child; Double-Blind Method; Eye In | 1995 |
A comparison of two dose regimens of epsilon aminocaproic acid in the prevention and management of secondary traumatic hyphemas.
Topics: Administration, Topical; Adolescent; Adrenal Cortex Hormones; Adult; Aminocaproates; Aminocaproic Ac | 1986 |
3 other studies available for aminocaproic acid and Intraocular Pressure
| Article | Year |
|---|---|
Recurrent bleeding following traumatic hyphema due to mild hemophilia B (Christmas disease).
Topics: Aminocaproic Acid; Anterior Eye Segment; Antifibrinolytic Agents; Child; Eye Injuries; Hemophilia B; | 2007 |
Intraocular pressure increase associated with traumatic epsilon-aminocaproic acid therapy for traumatic hyphema.
Topics: Aminocaproates; Aminocaproic Acid; Eye Injuries; Humans; Hyphema; Intraocular Pressure | 1989 |
Intraocular pressure increase associated with epsilon-aminocaproic acid therapy for traumatic hyphema.
Topics: Adolescent; Adult; Aminocaproates; Aminocaproic Acid; Anterior Chamber; Blood Coagulation; Erythrocy | 1988 |