Page last updated: 2024-10-17

aminocaproic acid and Embolism, Pulmonary

aminocaproic acid has been researched along with Embolism, Pulmonary in 15 studies

Aminocaproic Acid: An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
6-aminohexanoic acid : An epsilon-amino acid comprising hexanoic acid carrying an amino substituent at position C-6. Used to control postoperative bleeding, and to treat overdose effects of the thrombolytic agents streptokinase and tissue plasminogen activator.

Research Excerpts

ExcerptRelevanceReference
" We then evaluated the patients' hemoglobin, hematocrit, activated thromboplastin time, international normalized ration, fibrinogen, and thrombocyte count and symptoms of pulmonary embolism."3.73The role of antifibrinolytic agents in gynecologic cancer surgery. ( Aypar, U; Canbay, O; Celebi, N; Celebioglu, B; Karagoz, AH; Selcuk, M, 2006)
"One hundred consecutive patients treated with epsilon aminocaproic acid 24 grams daily prior to surgery for ruptured intracranial aneurysms have been compared with the previous 100 patients managed similarly but without anti-fibrinolytic drugs."3.66Anti-fibrinolytic treatment in the pre-operative management of subarachnoid haemorrhage caused by ruptured intracranial aneurysm. ( Ameen, AA; Illingworth, R, 1981)
" Deep vein thrombosis (DVT) can lead to pulmonary embolism (PE), but the mechanisms responsible for this progression are unknown."1.51Factor XIII Prevents Pulmonary Emboli in Mice by Stabilizing Deep Vein Thrombi. ( Gani, DM; Gross, PL; Kim, PY; Shaya, SA; Weitz, JI, 2019)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19908 (53.33)18.7374
1990's1 (6.67)18.2507
2000's1 (6.67)29.6817
2010's3 (20.00)24.3611
2020's2 (13.33)2.80

Authors

AuthorsStudies
Zheng, C3
Ma, J3
Xu, J3
Wu, L3
Wu, Y3
Liu, Y3
Shen, B3
Li, M1
Liu, Q1
Geng, P1
Shi, L1
Wang, Q1
Wang, P1
Roy, KM1
Rajan, GR1
Shaya, SA1
Gani, DM1
Weitz, JI1
Kim, PY1
Gross, PL1
STUDER, A2
REBER, K1
LOREZ, HP2
DOUGLAS, AS2
MCNICOL, GP2
BROWSE, NL1
JAMES, DC1
Celebi, N1
Celebioglu, B1
Selcuk, M1
Canbay, O1
Karagoz, AH1
Aypar, U1
Moser, KM1
Ameen, AA1
Illingworth, R1
Levati, A1
Minella, C1
Farina, ML1
D'Angelo, V1
Sopher, M1
Braunfeld, M1
Shackleton, C1
Busuttil, RW1
Sangwan, S1
Csete, M1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Oral Tranexamic Acid vs. Oral Aminocaproic Acid to Reduce Blood Loss, Transfusion Index and Complications After Total Hip Replacement. A Prospective, Randomized, Double Blind Clinical Trial[NCT04187014]Phase 290 participants (Actual)Interventional2020-02-06Completed
IV Tranexamic Acid Prior to Hysterectomy for Reduction of Intraoperative Blood Loss: A Randomized Placebo-Controlled Trial[NCT02911831]Early Phase 171 participants (Actual)Interventional2016-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for aminocaproic acid and Embolism, Pulmonary

ArticleYear
The optimal regimen, efficacy and safety of tranexamic acid and aminocaproic acid to reduce bleeding for patients after total hip arthroplasty: A systematic review and Bayesian network meta-analysis.
    Thrombosis research, 2023, Volume: 221

    Topics: Administration, Intravenous; Aminocaproic Acid; Antifibrinolytic Agents; Arthroplasty, Replacement,

2023
The optimal regimen, efficacy and safety of tranexamic acid and aminocaproic acid to reduce bleeding for patients after total hip arthroplasty: A systematic review and Bayesian network meta-analysis.
    Thrombosis research, 2023, Volume: 221

    Topics: Administration, Intravenous; Aminocaproic Acid; Antifibrinolytic Agents; Arthroplasty, Replacement,

2023
The optimal regimen, efficacy and safety of tranexamic acid and aminocaproic acid to reduce bleeding for patients after total hip arthroplasty: A systematic review and Bayesian network meta-analysis.
    Thrombosis research, 2023, Volume: 221

    Topics: Administration, Intravenous; Aminocaproic Acid; Antifibrinolytic Agents; Arthroplasty, Replacement,

2023
The optimal regimen, efficacy and safety of tranexamic acid and aminocaproic acid to reduce bleeding for patients after total hip arthroplasty: A systematic review and Bayesian network meta-analysis.
    Thrombosis research, 2023, Volume: 221

    Topics: Administration, Intravenous; Aminocaproic Acid; Antifibrinolytic Agents; Arthroplasty, Replacement,

2023
The Optimal Dose, Efficacy and Safety of Tranexamic Acid and Epsilon-Aminocaproic Acid to Reduce Bleeding in TKA: A Systematic Review and Bayesian Network Meta-analysis.
    Orthopaedic surgery, 2023, Volume: 15, Issue:4

    Topics: Administration, Intravenous; Aminocaproic Acid; Antifibrinolytic Agents; Arthroplasty, Replacement,

2023
Tranexamic acid versus aminocaproic acid for blood management after total knee and total hip arthroplasty: A systematic review and meta-analysis.
    International journal of surgery (London, England), 2018, Volume: 54, Issue:Pt A

    Topics: Aged; Aminocaproic Acid; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Repl

2018
THROMBOLYTIC THERAPY.
    British medical bulletin, 1964, Volume: 20

    Topics: Aminocaproates; Aminocaproic Acid; Anticoagulants; Biomedical Research; Deoxyribonuclease I; Drug Th

1964
Thromboembolic disease in the patient undergoing urologic surgery.
    The Urologic clinics of North America, 1983, Volume: 10, Issue:1

    Topics: Aminocaproic Acid; Anticoagulants; Clothing; Dextrans; Heparin; Humans; Postoperative Complications;

1983

Other Studies

10 other studies available for aminocaproic acid and Embolism, Pulmonary

ArticleYear
Reversal of ε-Aminocaproic Acid-Induced Massive Thromboemboli Using Tissue Plasminogen Activator During Cardiac Surgery: A Case Report.
    A&A practice, 2019, May-15, Volume: 12, Issue:10

    Topics: Aminocaproic Acid; Coronary Artery Bypass; Humans; Male; Middle Aged; Pulmonary Embolism; Tissue Pla

2019
Factor XIII Prevents Pulmonary Emboli in Mice by Stabilizing Deep Vein Thrombi.
    Thrombosis and haemostasis, 2019, Volume: 119, Issue:6

    Topics: Aminocaproic Acid; Animals; Anticoagulants; Antifibrinolytic Agents; Blood Platelets; Cells, Culture

2019
[EXPERIMENTAL STUDY ON THE PROBLEM OF THE SIGNIFICANCE OF INTRAVASCULAR FIBRIN FORMATION IN THE OCCURRANCE OF ARTERIOSCLEROTIC CHANGES IN THE WALLS OF BLOOD VESSELS].
    Pathologia et microbiologia, 1964, Volume: 27

    Topics: Aminocaproates; Aminocaproic Acid; Animals; Arteriosclerosis; Fibrin; Fibrinolysis; Glycosuria; Hema

1964
THROMBOLYTIC THERAPY.
    Proceedings of the Royal Society of Medicine, 1964, Volume: 57

    Topics: Aminocaproates; Aminocaproic Acid; Deoxyribonuclease I; Fibrinolysin; Fibrinolysis; Pharmacology; Ph

1964
STREPTOKINASE AND PULMONARY EMBOLISM.
    Lancet (London, England), 1964, Nov-14, Volume: 2, Issue:7368

    Topics: Aminocaproates; Aminocaproic Acid; Biomedical Research; Blood Coagulation Tests; Deoxyribonuclease I

1964
[INFLUENCE OF EPSILON-AMINOCAPROIC ACID ON THE PULMONARY VASCULAR CHANGES FOLLOWING INTRAVENOUS THROMBIN INFUSIONS IN RABBITS].
    Pathologia et microbiologia, 1965, Volume: 28

    Topics: Aminocaproates; Aminocaproic Acid; Animals; Injections; Injections, Intravenous; Lagomorpha; Pharmac

1965
The role of antifibrinolytic agents in gynecologic cancer surgery.
    Saudi medical journal, 2006, Volume: 27, Issue:5

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Blood Coagulation; Colloids; Crystalloid Solutions; Fema

2006
Anti-fibrinolytic treatment in the pre-operative management of subarachnoid haemorrhage caused by ruptured intracranial aneurysm.
    Journal of neurology, neurosurgery, and psychiatry, 1981, Volume: 44, Issue:3

    Topics: Adolescent; Adult; Aged; Aminocaproates; Aminocaproic Acid; Antifibrinolytic Agents; Child; Female;

1981
Potential hazards of antifibrinolytic treatment in subarachnoid haemorrhage.
    Thrombosis and haemostasis, 1980, Dec-19, Volume: 44, Issue:3

    Topics: Aminocaproates; Aminocaproic Acid; Coronary Disease; Humans; Male; Middle Aged; Pulmonary Embolism;

1980
Fatal pulmonary embolism during liver transplantation.
    Anesthesiology, 1997, Volume: 87, Issue:2

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Hepatitis C; Humans; Liver Cirrhosis;

1997