aminocaproic acid has been researched along with Disease Models, Animal in 20 studies
Aminocaproic Acid: An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
6-aminohexanoic acid : An epsilon-amino acid comprising hexanoic acid carrying an amino substituent at position C-6. Used to control postoperative bleeding, and to treat overdose effects of the thrombolytic agents streptokinase and tissue plasminogen activator.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This series of studies tested whether these drugs (aprotinin, desmopressin, tranexamic acid, epsilon-aminocaproic acid) could reduce bleeding due to traumatic injuries in two models of uncontrolled hemorrhage in rats." | 3.73 | Efficacy of FDA-approved hemostatic drugs to improve survival and reduce bleeding in rat models of uncontrolled hemorrhage. ( Cortez, DS; Dick, EJ; Pusateri, AE; Ryan, KL, 2006) |
| " Deep vein thrombosis (DVT) can lead to pulmonary embolism (PE), but the mechanisms responsible for this progression are unknown." | 1.51 | Factor XIII Prevents Pulmonary Emboli in Mice by Stabilizing Deep Vein Thrombi. ( Gani, DM; Gross, PL; Kim, PY; Shaya, SA; Weitz, JI, 2019) |
| " Further studies are needed to clarify optimal therapeutic dosing and to identify mechanisms of neuroprotection in rat SBI models." | 1.43 | Epsilon Aminocaproic Acid Pretreatment Provides Neuroprotection Following Surgically Induced Brain Injury in a Rat Model. ( Applegate, RL; Khatibi, N; Komanapalli, ES; Martin, RD; Rolland, W; Sherchan, P; Tang, J; Zhang, JH, 2016) |
| " Thus, pharmacokinetic changes in rats with acute renal failure induced by uranyl nitrate (U-ARF rats) were investigated in this study." | 1.38 | Reduced clearance of ε-acetamidocaproic acid in rats with acute renal failure induced by uranyl nitrate. ( Choi, YH; Han, SY; Lee, MG; Yang, SH; Yoon, I, 2012) |
| "Fibrin is an integral component of arterial thrombi." | 1.35 | Leukocyte urokinase plasminogen activator receptor and PSGL1 play a role in endogenous arterial fibrinolysis. ( Bai, X; Gross, PL; Weitz, JI, 2009) |
| "Lathyrism has been reviewed in respect to four overlapping phases: finding an animal model for neurolathyrism, characterizing osteolathyrism in respect to its possible use as an animal model for human diseases, such as Marfan's syndrome, idiopathic juvenile scoliosis, etc." | 1.27 | Lathyrism: mini-review and a comment on the lack of effect of protease inhibitors on osteolathyrism. ( Arunatut, O; Buranarugsa, MW; Yeager, VL, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (20.00) | 18.7374 |
| 1990's | 2 (10.00) | 18.2507 |
| 2000's | 4 (20.00) | 29.6817 |
| 2010's | 9 (45.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Solinski, HJ | 1 |
| Dranchak, P | 1 |
| Oliphant, E | 1 |
| Gu, X | 1 |
| Earnest, TW | 1 |
| Braisted, J | 1 |
| Inglese, J | 1 |
| Hoon, MA | 1 |
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Jing, J | 1 |
| Du, Z | 1 |
| Ji, S | 1 |
| Han, K | 1 |
| Jeong, HG | 1 |
| Cha, BG | 1 |
| Kang, DW | 1 |
| Kim, DY | 1 |
| Yang, W | 1 |
| Ki, SK | 1 |
| Kim, SI | 1 |
| Han, J | 1 |
| Kim, CK | 1 |
| Kim, J | 1 |
| Lee, SH | 1 |
| Shaya, SA | 1 |
| Gani, DM | 1 |
| Weitz, JI | 2 |
| Kim, PY | 1 |
| Gross, PL | 2 |
| Leroux, P | 1 |
| Omouendze, PL | 1 |
| Roy, V | 1 |
| Dourmap, N | 1 |
| Gonzalez, BJ | 1 |
| Brasse-Lagnel, C | 1 |
| Carmeliet, P | 1 |
| Leroux-Nicollet, I | 1 |
| Marret, S | 1 |
| Komanapalli, ES | 1 |
| Sherchan, P | 1 |
| Rolland, W | 1 |
| Khatibi, N | 1 |
| Martin, RD | 1 |
| Applegate, RL | 1 |
| Tang, J | 2 |
| Zhang, JH | 2 |
| Yang, P | 1 |
| Manaenko, A | 1 |
| Xu, F | 1 |
| Miao, L | 1 |
| Wang, G | 1 |
| Hu, X | 1 |
| Guo, ZN | 1 |
| Hu, Q | 1 |
| Hartman, RE | 1 |
| Pearce, WJ | 1 |
| Obenaus, A | 1 |
| Chen, G | 1 |
| Bai, X | 1 |
| Reust, DL | 1 |
| Reeves, ST | 1 |
| Abernathy, JH | 1 |
| Dixon, JA | 1 |
| Gaillard, WF | 1 |
| Mukherjee, R | 1 |
| Koval, CN | 1 |
| Stroud, RE | 1 |
| Spinale, FG | 1 |
| Han, SY | 1 |
| Yang, SH | 1 |
| Yoon, I | 1 |
| Lee, MG | 1 |
| Choi, YH | 1 |
| Rothwell, SW | 1 |
| Fudge, JM | 1 |
| Reid, TJ | 1 |
| Krishnamurti, C | 1 |
| Ryan, KL | 1 |
| Cortez, DS | 1 |
| Dick, EJ | 1 |
| Pusateri, AE | 1 |
| Shen, ZJ | 1 |
| Wang, Y | 1 |
| Ding, GQ | 1 |
| Pan, CW | 1 |
| Zheng, RM | 1 |
| Hruby, Z | 1 |
| Wendycz, D | 1 |
| Kopeć, W | 1 |
| Czerchawski, L | 1 |
| Józefowiak, M | 1 |
| Rabczyński, J | 1 |
| Vidal, RF | 1 |
| Dikstein, S | 1 |
| Brodner, RA | 1 |
| Vangilder, JC | 1 |
| Collins, WF | 1 |
| Racanelli, AL | 1 |
| Diemer, MJ | 1 |
| Dobies, AC | 1 |
| Dubin, JR | 1 |
| Reilly, TM | 1 |
| Yeager, VL | 1 |
| Buranarugsa, MW | 1 |
| Arunatut, O | 1 |
| Escolar, G | 1 |
| Camarasa, J | 1 |
| Navarro, C | 1 |
| Vernetta, C | 1 |
| Bulbena, O | 1 |
20 other studies available for aminocaproic acid and Disease Models, Animal
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Urinary proteome analysis of acute hypercoagulable state in rat model induced by ε-aminocaproic acid.
Topics: Aminocaproic Acid; Animals; Antifibrinolytic Agents; Biomarkers; Disease Models, Animal; Dose-Respon | 2019 |
Ceria Nanoparticles Fabricated with 6-Aminohexanoic Acid that Overcome Systemic Inflammatory Response Syndrome.
Topics: Aminocaproic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Blotting, Western; Cerium; Disea | 2019 |
Factor XIII Prevents Pulmonary Emboli in Mice by Stabilizing Deep Vein Thrombi.
Topics: Aminocaproic Acid; Animals; Anticoagulants; Antifibrinolytic Agents; Blood Platelets; Cells, Culture | 2019 |
Age-dependent neonatal intracerebral hemorrhage in plasminogen activator inhibitor 1 knockout mice.
Topics: Age Factors; Aging; Aminocaproic Acid; Animals; Animals, Newborn; Aprotinin; Cerebral Hemorrhage; Di | 2014 |
Epsilon Aminocaproic Acid Pretreatment Provides Neuroprotection Following Surgically Induced Brain Injury in a Rat Model.
Topics: Aminocaproic Acid; Animals; Antifibrinolytic Agents; Behavior, Animal; Brain; Brain Edema; Brain Inj | 2016 |
Role of PDGF-D and PDGFR-β in neuroinflammation in experimental ICH mice model.
Topics: Aminocaproic Acid; Animals; Basal Ganglia; Brain Edema; Cerebral Hemorrhage; Disease Models, Animal; | 2016 |
Leukocyte urokinase plasminogen activator receptor and PSGL1 play a role in endogenous arterial fibrinolysis.
Topics: Aminocaproic Acid; Animals; Arterioles; Blood Platelets; Disease Models, Animal; Fibrin; Fibrinolysi | 2009 |
Interstitial plasmin activity with epsilon aminocaproic acid: temporal and regional heterogeneity.
Topics: Aminocaproic Acid; Analysis of Variance; Animals; Antifibrinolytic Agents; Area Under Curve; Disease | 2010 |
Reduced clearance of ε-acetamidocaproic acid in rats with acute renal failure induced by uranyl nitrate.
Topics: Acute Kidney Injury; Administration, Oral; Aminocaproates; Aminocaproic Acid; Animals; Area Under Cu | 2012 |
Epsilon-amino caproic acid additive decreases fibrin bandage performance in a swine arterial bleeding model.
Topics: Aminocaproic Acid; Animals; Arteries; Blood Coagulation; Blood Coagulation Tests; Blood Loss, Surgic | 2002 |
Efficacy of FDA-approved hemostatic drugs to improve survival and reduce bleeding in rat models of uncontrolled hemorrhage.
Topics: Aminocaproic Acid; Animals; Antifibrinolytic Agents; Aprotinin; Deamino Arginine Vasopressin; Diseas | 2006 |
Study on enhancement of fibronectin-mediated bacillus Calmette-Guérin attachment to urinary bladder wall in rabbits.
Topics: 4-Aminobenzoic Acid; Administration, Intravesical; Aminocaproic Acid; Animals; Antifibrinolytic Agen | 2007 |
Effect of antiproteolytic drugs: epsilon-aminocaproic acid (EACA) and aprotinin on experimental anti-GBM nephritis.
Topics: Aminocaproic Acid; Animals; Antifibrinolytic Agents; Aprotinin; Creatinine; Disease Models, Animal; | 1996 |
[Rabbit experimental glaucoma--preliminary study (author's transl)].
Topics: Aminocaproates; Aminocaproic Acid; Animals; Disease Models, Animal; Disseminated Intravascular Coagu | 1978 |
The effect of antifibrinolytic therapy in experimental spinal cord trauma.
Topics: Aminocaproates; Aminocaproic Acid; Animals; Antifibrinolytic Agents; Cats; Disease Models, Animal; E | 1977 |
Comparison of recombinant plasminogen activator inhibitor-1 and epsilon amino caproic acid in a hemorrhagic rabbit model.
Topics: Amino Acid Sequence; Aminocaproic Acid; Animals; Disease Models, Animal; Hemorrhage; Male; Molecular | 1992 |
Lathyrism: mini-review and a comment on the lack of effect of protease inhibitors on osteolathyrism.
Topics: Aminocaproates; Aminocaproic Acid; Aminopropionitrile; Animals; Aprotinin; Bone Diseases; Collagen; | 1985 |
Antiulcerogenic activity of zinc acexamate in different experimental models.
Topics: Aminocaproates; Aminocaproic Acid; Animals; Bile Acids and Salts; Disease Models, Animal; Female; Ma | 1987 |