Page last updated: 2024-10-17

aminocaproic acid and Craniofacial Abnormalities

aminocaproic acid has been researched along with Craniofacial Abnormalities in 2 studies

Aminocaproic Acid: An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
6-aminohexanoic acid : An epsilon-amino acid comprising hexanoic acid carrying an amino substituent at position C-6. Used to control postoperative bleeding, and to treat overdose effects of the thrombolytic agents streptokinase and tissue plasminogen activator.

Craniofacial Abnormalities: Congenital structural deformities, malformations, or other abnormalities of the cranium and facial bones.

Research Excerpts

ExcerptRelevanceReference
"The aim was to utilize the Pediatric Craniofacial Surgery Perioperative Registry database to identify the safety profile of antifibrinolytic therapy for cranial vault reconstructive surgery by reporting the incidence of adverse events as they relate to exposure to tranexamic acid and aminocaproic acid compared to no exposure to antifibrinolytics."1.46Safety of antifibrinolytics in cranial vault reconstructive surgery: a report from the pediatric craniofacial collaborative group. ( Cladis, FP; Fernandez, AM; Glover, CD; Goobie, SM; Huang, H; Reddy, SK; Stricker, PA; Zurakowski, D, 2017)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Goobie, SM1
Cladis, FP1
Glover, CD1
Huang, H1
Reddy, SK1
Fernandez, AM1
Zurakowski, D1
Stricker, PA2
Zuppa, AF1
Fiadjoe, JE1
Maxwell, LG1
Sussman, EM1
Pruitt, EY1
Goebel, TK1
Gastonguay, MR1
Taylor, JA1
Bartlett, SP1
Schreiner, MS1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy of ε-Aminocaproic Acid (EACA) in Children Undergoing Craniofacial Reconstruction Surgery[NCT02229968]Phase 222 participants (Actual)Interventional2014-10-31Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for aminocaproic acid and Craniofacial Abnormalities

ArticleYear
Population pharmacokinetics of epsilon-aminocaproic acid in infants undergoing craniofacial reconstruction surgery.
    British journal of anaesthesia, 2013, Volume: 110, Issue:5

    Topics: Age Factors; Aminocaproic Acid; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Bo

2013

Other Studies

1 other study available for aminocaproic acid and Craniofacial Abnormalities

ArticleYear
Safety of antifibrinolytics in cranial vault reconstructive surgery: a report from the pediatric craniofacial collaborative group.
    Paediatric anaesthesia, 2017, Volume: 27, Issue:3

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Blood Loss, Surgical; Child; Child, Preschool; Cooperati

2017