aminocaproic acid has been researched along with Christmas Disease in 14 studies
Aminocaproic Acid: An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
6-aminohexanoic acid : An epsilon-amino acid comprising hexanoic acid carrying an amino substituent at position C-6. Used to control postoperative bleeding, and to treat overdose effects of the thrombolytic agents streptokinase and tissue plasminogen activator.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study evaluated the safety and efficacy of combined treatment with epsilon-aminocaproic acid or tranexamic acid and monoclonal antibody purified factor IX (MAb factor IX) for prophylaxis against bleeding in eight hemophilia B patients undergoing nine dental extraction procedures." | 5.08 | Safety and efficacy of purified factor IX concentrate and antifibrinolytic agents for dental extractions in hemophilia B. ( Djulbegovic, B; Goldsmith, G; Hadley, T; Joseph, G; Kushner, GM; Marasa, M; Pesto, A, 1996) |
| "In people with haemophilia or other congenital bleeding disorders undergoing surgical interventions, haemostatic treatment is needed in order to correct the underlying coagulation abnormalities and minimise the bleeding risk." | 2.52 | Treatment for preventing bleeding in people with haemophilia or other congenital bleeding disorders undergoing surgery. ( Coppola, A; Di Minno, MN; Tufano, A; Windyga, J; Yeung, C, 2015) |
| "Haemophilia is a congenital, life-long disorder that may cause major disabilities." | 2.37 | Comprehensive management of haemophilia. ( Dietrich, SL; Kasper, CK, 1985) |
| " Symptoms like mild nausea and vertigo were seen as the side-effects of this medicine when high intravenous dosage was administered." | 1.32 | Role of epsilon amino caproic acid in the management of haemophilic patients with inhibitors. ( Ghosh, K; Jijina, F; Mohanty, D; Shetty, S, 2004) |
| "In attenuated forms of haemophilia B (factor IX level between 5 and 15%) haemorrhages may be only occasional and occur only late in life." | 1.26 | [Heavy haematuria as the presentation of attenuated haemophilia B (author's transl)]. ( Bollack, C; Dufour, A; Guyen Qui, JL; Kalogjera, V; Masson, JC; Mayer, G; Oliveux, A, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (50.00) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 3 (21.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Coppola, A | 1 |
| Windyga, J | 1 |
| Tufano, A | 1 |
| Yeung, C | 1 |
| Di Minno, MN | 1 |
| van Galen, KP | 1 |
| Engelen, ET | 1 |
| Mauser-Bunschoten, EP | 1 |
| van Es, RJ | 1 |
| Schutgens, RE | 1 |
| Fogarty, PF | 1 |
| Kouides, P | 1 |
| STRAUSS, HS | 1 |
| KEVY, SV | 1 |
| DIAMOND, LK | 1 |
| TSEVRENIS, H | 1 |
| MANDALAKI, T | 1 |
| Ghosh, K | 1 |
| Shetty, S | 1 |
| Jijina, F | 1 |
| Mohanty, D | 1 |
| Wilker, SC | 1 |
| Singh, A | 1 |
| Ellis, FJ | 1 |
| Olivier, M | 1 |
| Oliveux, A | 1 |
| Masson, JC | 1 |
| Dufour, A | 1 |
| Guyen Qui, JL | 1 |
| Kalogjera, V | 1 |
| Mayer, G | 1 |
| Bollack, C | 1 |
| Djulbegovic, B | 1 |
| Marasa, M | 1 |
| Pesto, A | 1 |
| Kushner, GM | 1 |
| Hadley, T | 1 |
| Joseph, G | 1 |
| Goldsmith, G | 1 |
| Medina Pérez, A | 1 |
| De las Nieves, MA | 1 |
| Vinckier, F | 1 |
| Vermylen, J | 1 |
| Kasper, CK | 1 |
| Dietrich, SL | 1 |
| Ambriz, R | 1 |
| Pizzuto, J | 1 |
| Guillen, C | 1 |
3 reviews available for aminocaproic acid and Christmas Disease
| Article | Year |
|---|---|
Treatment for preventing bleeding in people with haemophilia or other congenital bleeding disorders undergoing surgery.
Topics: Aminocaproic Acid; Antifibrinolytic Agents; Blood Loss, Surgical; Factor VIIa; Hemophilia A; Hemophi | 2015 |
Antifibrinolytic therapy for preventing oral bleeding in patients with haemophilia or Von Willebrand disease undergoing minor oral surgery or dental extractions.
Topics: Aminocaproic Acid; Antifibrinolytic Agents; Blood Loss, Surgical; Factor IX; Factor VIII; Hemophilia | 2015 |
Comprehensive management of haemophilia.
Topics: Aminocaproic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Blood Coagulation Facto | 1985 |
2 trials available for aminocaproic acid and Christmas Disease
| Article | Year |
|---|---|
Ineffectiveness of prophylactic epsilon aminocaproic acid in severe hemophilia.
Topics: Adolescent; Adult; Aminocaproic Acid; Blood Component Transfusion; Child; Child, Preschool; Double-B | 1965 |
Safety and efficacy of purified factor IX concentrate and antifibrinolytic agents for dental extractions in hemophilia B.
Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Factor IX; Hemophilia B; Hemorrhage; Humans; Midd | 1996 |
9 other studies available for aminocaproic acid and Christmas Disease
| Article | Year |
|---|---|
How we treat: patients with haemophilia undergoing screening colonoscopy.
Topics: Aminocaproic Acid; Antifibrinolytic Agents; Colonoscopy; Factor IX; Hemophilia A; Hemophilia B; Huma | 2010 |
HAEMATURIA IN A HAEMOPHILIAC TREATED WITH E-AMINOCAPROIC ACID.
Topics: Aminocaproates; Aminocaproic Acid; Blood Platelet Disorders; Blood Transfusion; Drug Therapy; Hematu | 1965 |
Role of epsilon amino caproic acid in the management of haemophilic patients with inhibitors.
Topics: Adolescent; Adult; Aminocaproic Acid; Antifibrinolytic Agents; Child; Factor VIII; Hemophilia A; Hem | 2004 |
Recurrent bleeding following traumatic hyphema due to mild hemophilia B (Christmas disease).
Topics: Aminocaproic Acid; Anterior Eye Segment; Antifibrinolytic Agents; Child; Eye Injuries; Hemophilia B; | 2007 |
[Dental treatment of a hemophilic patient].
Topics: Aminocaproic Acid; Child, Preschool; Dental Care; Factor VIII; Hemophilia A; Hemophilia B; Humans; L | 1981 |
[Heavy haematuria as the presentation of attenuated haemophilia B (author's transl)].
Topics: Adult; Aminocaproic Acid; Cystitis; Eosinophils; Factor IX; Hematuria; Hemophilia B; Humans; Male; U | 1980 |
[Antifibrinolytics as a treatment for severe factor XI deficiency in laryngeal surgery].
Topics: Aminocaproic Acid; Antifibrinolytic Agents; Hemophilia B; Humans; Intraoperative Complications; Lary | 1999 |
Dental extractions in hemophilia: reflections on 10 years' experience.
Topics: Aminocaproic Acid; Bandages; Cellulose, Oxidized; Dental Care for Disabled; Factor IX; Factor VIII; | 1985 |
Danazol in hemophilia.
Topics: Adult; Aminocaproic Acid; Danazol; Fibrinolysis; Hemophilia A; Hemophilia B; Humans; Male; Pregnadie | 1985 |