aminocaproic acid has been researched along with Cerebral Hemorrhage in 14 studies
Aminocaproic Acid: An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
6-aminohexanoic acid : An epsilon-amino acid comprising hexanoic acid carrying an amino substituent at position C-6. Used to control postoperative bleeding, and to treat overdose effects of the thrombolytic agents streptokinase and tissue plasminogen activator.
Cerebral Hemorrhage: Bleeding into one or both CEREBRAL HEMISPHERES including the BASAL GANGLIA and the CEREBRAL CORTEX. It is often associated with HYPERTENSION and CRANIOCEREBRAL TRAUMA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Up to 40% of primary intracerebral hemorrhages (ICHs) expand within the first 24 hours (natural history)." | 6.71 | Treatment of acute intracerebral hemorrhage with epsilon-aminocaproic acid: a pilot study. ( Grotta, JC; Hall, CE; Morgenstern, LB; Piriyawat, P; Yawn, DH, 2004) |
| "The incidence and severity of cerebral vasospasm and hydrocephalus following induced subarachnoid hemorrhage in an experimental group of animals that subsequently received epsilon-aminocaproic acid was compared to that seen in a control group that received no antifibrinolytic therapy." | 3.67 | An experimental study of the influence of antifibrinolytic therapy on post-subarachnoid-hemorrhagic cerebral vasospasm and hydrocephalus. ( Dujovny, M; Heros, RC; Kenning, JA; Latchaw, RE; Nelson, D, 1984) |
| "Up to 40% of primary intracerebral hemorrhages (ICHs) expand within the first 24 hours (natural history)." | 2.71 | Treatment of acute intracerebral hemorrhage with epsilon-aminocaproic acid: a pilot study. ( Grotta, JC; Hall, CE; Morgenstern, LB; Piriyawat, P; Yawn, DH, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (42.86) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 3 (21.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Al-Shahi Salman, R | 2 |
| Law, ZK | 1 |
| Bath, PM | 1 |
| Steiner, T | 1 |
| Sprigg, N | 1 |
| Leroux, P | 1 |
| Omouendze, PL | 1 |
| Roy, V | 1 |
| Dourmap, N | 1 |
| Gonzalez, BJ | 1 |
| Brasse-Lagnel, C | 1 |
| Carmeliet, P | 1 |
| Leroux-Nicollet, I | 1 |
| Marret, S | 1 |
| Yang, P | 1 |
| Manaenko, A | 1 |
| Xu, F | 1 |
| Miao, L | 1 |
| Wang, G | 1 |
| Hu, X | 1 |
| Guo, ZN | 1 |
| Hu, Q | 1 |
| Hartman, RE | 1 |
| Pearce, WJ | 1 |
| Obenaus, A | 1 |
| Zhang, JH | 1 |
| Chen, G | 1 |
| Tang, J | 1 |
| Piriyawat, P | 1 |
| Morgenstern, LB | 1 |
| Yawn, DH | 1 |
| Hall, CE | 1 |
| Grotta, JC | 1 |
| You, H | 1 |
| Al-Shahi, R | 1 |
| Kenning, JA | 1 |
| Heros, RC | 1 |
| Dujovny, M | 1 |
| Latchaw, RE | 1 |
| Nelson, D | 1 |
| Horwitz, JR | 1 |
| Cofer, BR | 1 |
| Warner, BW | 1 |
| Cheu, HW | 1 |
| Lally, KP | 1 |
| Eninia, GI | 1 |
| Metra, MIa | 1 |
| Gaĭle, NV | 1 |
| Scott, RM | 1 |
| Garrido, E | 1 |
| Post, KD | 1 |
| Flamm, ES | 1 |
| Goodgold, A | 1 |
| Ransohoff, J | 1 |
| Langtitt, TW | 1 |
| Arocha-Piñango, CL | 1 |
| de Bosch, NB | 1 |
| Torres, A | 1 |
| Goldstein, C | 1 |
| Nouel, A | 1 |
| Argüello, A | 1 |
| Carvajal, Z | 1 |
| Guerrero, B | 1 |
| Ojeda, A | 1 |
| Rodriguez, A | 1 |
| Gootenberg, JE | 1 |
| Buchanan, GR | 1 |
| Holtkamp, CA | 1 |
| Casey, CS | 1 |
3 reviews available for aminocaproic acid and Cerebral Hemorrhage
| Article | Year |
|---|---|
Haemostatic therapies for acute spontaneous intracerebral haemorrhage.
Topics: Acute Disease; Adult; Aminocaproic Acid; Antifibrinolytic Agents; Cerebral Hemorrhage; Disease Progr | 2018 |
Haemostatic drug therapies for acute spontaneous intracerebral haemorrhage.
Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Cerebral Hemorrhage; Factor VIIa; Hemostasis; Hem | 2009 |
Haemostatic drug therapies for acute primary intracerebral haemorrhage.
Topics: Aminocaproic Acid; Antifibrinolytic Agents; Cerebral Hemorrhage; Factor VII; Hemostasis; Hemostatics | 2006 |
2 trials available for aminocaproic acid and Cerebral Hemorrhage
| Article | Year |
|---|---|
Treatment of acute intracerebral hemorrhage with epsilon-aminocaproic acid: a pilot study.
Topics: Acute Disease; Adult; Aged; Aminocaproic Acid; Antifibrinolytic Agents; Cerebral Hemorrhage; Drug Ad | 2004 |
A multicenter trial of 6-aminocaproic acid (Amicar) in the prevention of bleeding in infants on ECMO.
Topics: Aminocaproic Acid; Antifibrinolytic Agents; Cerebral Hemorrhage; Double-Blind Method; Extracorporeal | 1998 |
9 other studies available for aminocaproic acid and Cerebral Hemorrhage
| Article | Year |
|---|---|
Age-dependent neonatal intracerebral hemorrhage in plasminogen activator inhibitor 1 knockout mice.
Topics: Age Factors; Aging; Aminocaproic Acid; Animals; Animals, Newborn; Aprotinin; Cerebral Hemorrhage; Di | 2014 |
Role of PDGF-D and PDGFR-β in neuroinflammation in experimental ICH mice model.
Topics: Aminocaproic Acid; Animals; Basal Ganglia; Brain Edema; Cerebral Hemorrhage; Disease Models, Animal; | 2016 |
An experimental study of the influence of antifibrinolytic therapy on post-subarachnoid-hemorrhagic cerebral vasospasm and hydrocephalus.
Topics: Aminocaproates; Aminocaproic Acid; Animals; Cerebral Angiography; Cerebral Hemorrhage; Hydrocephalus | 1984 |
[Action of epsilon-aminocaproic acid on cerebral hemodynamics].
Topics: Aminocaproates; Aminocaproic Acid; Cerebral Hemorrhage; Cerebrovascular Circulation; Drug Evaluation | 1979 |
Spontaneous thrombosis of an intracranial aneurysm during treatment with epsilon aminocaproic acid.
Topics: Adult; Aminocaproates; Aminocaproic Acid; Cerebral Hemorrhage; Female; Humans; Intracranial Aneurysm | 1977 |
Ruptured intracranial aneurysms. Case morbidity and mortality.
Topics: Adult; Aged; Aminocaproic Acid; Cerebral Hemorrhage; Humans; Hydrochlorothiazide; Hypertension; Intr | 1977 |
Conservative care of intracranial hemorrhage.
Topics: Aminocaproic Acid; Blood Pressure; Brain Edema; Cerebral Hemorrhage; Humans; Hydrocephalus; Hyperton | 1977 |
Six new cases of a caterpillar-induced bleeding syndrome.
Topics: Adult; Aminocaproic Acid; Animals; Aprotinin; Blood Coagulation; Cerebral Hemorrhage; Female; Fibrin | 1992 |
Severe hemorrhage in a patient with gray platelet syndrome.
Topics: Aminocaproic Acid; Blood Platelet Disorders; Blood Platelets; Blood Transfusion; Cerebral Hemorrhage | 1986 |