Page last updated: 2024-10-17

aminocaproic acid and Burns

aminocaproic acid has been researched along with Burns in 4 studies

Aminocaproic Acid: An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
6-aminohexanoic acid : An epsilon-amino acid comprising hexanoic acid carrying an amino substituent at position C-6. Used to control postoperative bleeding, and to treat overdose effects of the thrombolytic agents streptokinase and tissue plasminogen activator.

Burns: Injuries to tissues caused by contact with heat, steam, chemicals (BURNS, CHEMICAL), electricity (BURNS, ELECTRIC), or the like.

Research Excerpts

ExcerptRelevanceReference
"Tranexamic acid has also emerged as a promising agent in aesthetic surgery and burn care, due to its favorable safety profile and role in reducing blood loss, achieving an improved surgical field, and reducing edema and ecchymosis."2.58Antifibrinolytic Agents in Plastic Surgery: Current Practices and Future Directions. ( Brown, S; Taub, PJ; Yao, A, 2018)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brown, S1
Yao, A1
Taub, PJ1
MONSAINGEON, A1
TANRET, P1
MADERA, R1
MARSICO, V1
Levitskiĭ, AP1
Zheleznyĭ, VI1
Litvinov, PG1
Kadyshev, IuG1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Use of TRanEXamic Acid in Reduction Mammoplasty (TREX-ARM): a Double-blinded Randomized Controlled Trial[NCT04947514]Phase 498 participants (Actual)Interventional2021-10-29Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Breasts With Development of Hematoma

The number of breasts with clinically significant hematoma (collection of blood under the skin) requiring either conservative management or operative washout was determined. (NCT04947514)
Timeframe: Up to 30 days

Interventionbreasts (Number)
Treatment Side (Right or Left)2
Placebo Side (Right or Left)1

Number of Participants Requiring a Blood Transfusion

The number of participants requiring blood transfusion was based on the postoperative decline in hematocrit level (NCT04947514)
Timeframe: Up to 30 days

InterventionParticipants (Count of Participants)
Treatment Side (Right or Left)0
Placebo Side (Right or Left)0

Number of Participants With Deep Vein Thrombosis/Venous Thromboembolism

Incidence of clinically significant deep vein thrombosis or pulmonary embolism detected on imaging (ultrasound or CT scan) (NCT04947514)
Timeframe: Up to 30 days

InterventionParticipants (Count of Participants)
Treatment Side (Right or Left)0
Placebo Side (Right or Left)0

Reviews

1 review available for aminocaproic acid and Burns

ArticleYear
Antifibrinolytic Agents in Plastic Surgery: Current Practices and Future Directions.
    Plastic and reconstructive surgery, 2018, Volume: 141, Issue:6

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Burns; Clinical Trials as Topic; Cohort Studies; Forecas

2018

Other Studies

3 other studies available for aminocaproic acid and Burns

ArticleYear
[TOWARD A TREATMENT OF TEGUMENTAL LESIONS OF THERMAL ORIGIN].
    Annales de chirurgie, 1964, Volume: 18

    Topics: Aminocaproates; Aminocaproic Acid; Anti-Allergic Agents; Burns; Carbon Dioxide; Cortisone; Cytochrom

1964
[EPSILON AMINOCAPROIC ACID AND EXPERIMENTAL BURNS. II ].
    Rivista di patologia e clinica, 1964, Volume: 19

    Topics: Aminocaproates; Aminocaproic Acid; Animals; Burns; Lagomorpha; Pharmacology; Rabbits; Research; Woun

1964
[Use of epsilon-aminocaproic acid for treating granulating burn wounds].
    Vestnik khirurgii imeni I. I. Grekova, 1986, Volume: 137, Issue:10

    Topics: Adolescent; Adult; Aged; Aminocaproates; Aminocaproic Acid; Bandages; Burns; Combined Modality Thera

1986