Page last updated: 2024-10-17

aminocaproic acid and Brain Ischemia

aminocaproic acid has been researched along with Brain Ischemia in 7 studies

Aminocaproic Acid: An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
6-aminohexanoic acid : An epsilon-amino acid comprising hexanoic acid carrying an amino substituent at position C-6. Used to control postoperative bleeding, and to treat overdose effects of the thrombolytic agents streptokinase and tissue plasminogen activator.

Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.

Research Excerpts

ExcerptRelevanceReference
"ε-Aminocaproic acid (EACA) has been used to reduce the rate of cerebral aneurysm rerupture before definitive treatment."5.38ε-Aminocaproic acid in angiographically negative subarachnoid hemorrhage patients is safe: a retrospective review of 83 consecutive patients. ( Barrow, DL; Cawley, CM; Hui, FK; Lieber, M; Moskowitz, SI; Schuette, AJ; Spiotta, AM, 2012)
"Long-term administration of the antifibrinolytic agent epsilon aminocaproic acid (EACA) reduces the rate of rehemorrhage in patients with aneurysmal subarachnoid hemorrhage (SAH), but is associated with cerebral ischemia."3.76Short-term antifibrinolytic therapy before early aneurysm treatment in subarachnoid hemorrhage: effects on rehemorrhage, cerebral ischemia, and hydrocephalus. ( Ardelt, AA; Fisher, WS; Harrigan, MR; Rajneesh, KF, 2010)
"Aminocaproic acid was given for hemorrhagic conversion of acute ischemic stroke in 7 of 16 patients and other types of hemorrhages in the remaining patients."1.56Aminocaproic Acid for the Reversal of Alteplase: A Case Series. ( Berger, K; Lesch, CA; Verkerk, BS, 2020)
"ε-Aminocaproic acid (EACA) has been used to reduce the rate of cerebral aneurysm rerupture before definitive treatment."1.38ε-Aminocaproic acid in angiographically negative subarachnoid hemorrhage patients is safe: a retrospective review of 83 consecutive patients. ( Barrow, DL; Cawley, CM; Hui, FK; Lieber, M; Moskowitz, SI; Schuette, AJ; Spiotta, AM, 2012)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (85.71)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Verkerk, BS1
Berger, K1
Lesch, CA1
Baharoglu, MI1
Germans, MR1
Rinkel, GJ1
Algra, A1
Vermeulen, M1
van Gijn, J1
Roos, YB1
Harrigan, MR1
Rajneesh, KF1
Ardelt, AA1
Fisher, WS1
Nina, P1
Schisano, G1
Thomas, G1
Evelyne, E1
Hui, FK2
Schuette, AJ2
Lieber, M1
Spiotta, AM1
Moskowitz, SI1
Barrow, DL2
Cawley, CM2
Obuchowski, NA1
Walkup, RR1
Samuels, OB1

Reviews

1 review available for aminocaproic acid and Brain Ischemia

ArticleYear
Antifibrinolytic therapy for aneurysmal subarachnoid haemorrhage.
    The Cochrane database of systematic reviews, 2013, Aug-30, Issue:8

    Topics: Administration, Oral; Aminocaproic Acid; Antifibrinolytic Agents; Brain Ischemia; Confidence Interva

2013

Other Studies

6 other studies available for aminocaproic acid and Brain Ischemia

ArticleYear
Aminocaproic Acid for the Reversal of Alteplase: A Case Series.
    Journal of pharmacy practice, 2020, Volume: 33, Issue:6

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Brain Ischemia; Humans; Stroke; Tissue Plasminogen Activ

2020
Short-term antifibrinolytic therapy before early aneurysm treatment in subarachnoid hemorrhage: effects on rehemorrhage, cerebral ischemia, and hydrocephalus.
    Neurosurgery, 2010, Volume: 67, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aminocaproic Acid; Antifibrinolytic Agents; Brain Ischem

2010
Antifibrinolytic drugs in subarachnoid hemorrhage by ruptured aneurysms.
    Neurosurgery, 2011, Volume: 68, Issue:6

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Brain Ischemia; Female; Humans; Hydrocephalus; Male; Sub

2011
Antifibrinolytic in subarachnoid hemorrhage.
    Neurosurgery, 2011, Volume: 69, Issue:2

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Brain Ischemia; Female; Humans; Hydrocephalus; Male; Sub

2011
ε-Aminocaproic acid in angiographically negative subarachnoid hemorrhage patients is safe: a retrospective review of 83 consecutive patients.
    Neurosurgery, 2012, Volume: 70, Issue:3

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Brain Ischemia; Case-Control Studies; Cerebral An

2012
An examination of aneurysm rerupture rates with epsilon aminocaproic acid.
    Neurocritical care, 2013, Volume: 19, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aminocaproic Acid; Aneurysm, Ruptured; Antifibrinolytic

2013