aminocaproic acid has been researched along with Brain Ischemia in 7 studies
Aminocaproic Acid: An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
6-aminohexanoic acid : An epsilon-amino acid comprising hexanoic acid carrying an amino substituent at position C-6. Used to control postoperative bleeding, and to treat overdose effects of the thrombolytic agents streptokinase and tissue plasminogen activator.
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "ε-Aminocaproic acid (EACA) has been used to reduce the rate of cerebral aneurysm rerupture before definitive treatment." | 5.38 | ε-Aminocaproic acid in angiographically negative subarachnoid hemorrhage patients is safe: a retrospective review of 83 consecutive patients. ( Barrow, DL; Cawley, CM; Hui, FK; Lieber, M; Moskowitz, SI; Schuette, AJ; Spiotta, AM, 2012) |
| "Long-term administration of the antifibrinolytic agent epsilon aminocaproic acid (EACA) reduces the rate of rehemorrhage in patients with aneurysmal subarachnoid hemorrhage (SAH), but is associated with cerebral ischemia." | 3.76 | Short-term antifibrinolytic therapy before early aneurysm treatment in subarachnoid hemorrhage: effects on rehemorrhage, cerebral ischemia, and hydrocephalus. ( Ardelt, AA; Fisher, WS; Harrigan, MR; Rajneesh, KF, 2010) |
| "Aminocaproic acid was given for hemorrhagic conversion of acute ischemic stroke in 7 of 16 patients and other types of hemorrhages in the remaining patients." | 1.56 | Aminocaproic Acid for the Reversal of Alteplase: A Case Series. ( Berger, K; Lesch, CA; Verkerk, BS, 2020) |
| "ε-Aminocaproic acid (EACA) has been used to reduce the rate of cerebral aneurysm rerupture before definitive treatment." | 1.38 | ε-Aminocaproic acid in angiographically negative subarachnoid hemorrhage patients is safe: a retrospective review of 83 consecutive patients. ( Barrow, DL; Cawley, CM; Hui, FK; Lieber, M; Moskowitz, SI; Schuette, AJ; Spiotta, AM, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (85.71) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Verkerk, BS | 1 |
| Berger, K | 1 |
| Lesch, CA | 1 |
| Baharoglu, MI | 1 |
| Germans, MR | 1 |
| Rinkel, GJ | 1 |
| Algra, A | 1 |
| Vermeulen, M | 1 |
| van Gijn, J | 1 |
| Roos, YB | 1 |
| Harrigan, MR | 1 |
| Rajneesh, KF | 1 |
| Ardelt, AA | 1 |
| Fisher, WS | 1 |
| Nina, P | 1 |
| Schisano, G | 1 |
| Thomas, G | 1 |
| Evelyne, E | 1 |
| Hui, FK | 2 |
| Schuette, AJ | 2 |
| Lieber, M | 1 |
| Spiotta, AM | 1 |
| Moskowitz, SI | 1 |
| Barrow, DL | 2 |
| Cawley, CM | 2 |
| Obuchowski, NA | 1 |
| Walkup, RR | 1 |
| Samuels, OB | 1 |
1 review available for aminocaproic acid and Brain Ischemia
| Article | Year |
|---|---|
Antifibrinolytic therapy for aneurysmal subarachnoid haemorrhage.
Topics: Administration, Oral; Aminocaproic Acid; Antifibrinolytic Agents; Brain Ischemia; Confidence Interva | 2013 |
6 other studies available for aminocaproic acid and Brain Ischemia
| Article | Year |
|---|---|
Aminocaproic Acid for the Reversal of Alteplase: A Case Series.
Topics: Aminocaproic Acid; Antifibrinolytic Agents; Brain Ischemia; Humans; Stroke; Tissue Plasminogen Activ | 2020 |
Short-term antifibrinolytic therapy before early aneurysm treatment in subarachnoid hemorrhage: effects on rehemorrhage, cerebral ischemia, and hydrocephalus.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aminocaproic Acid; Antifibrinolytic Agents; Brain Ischem | 2010 |
Antifibrinolytic drugs in subarachnoid hemorrhage by ruptured aneurysms.
Topics: Aminocaproic Acid; Antifibrinolytic Agents; Brain Ischemia; Female; Humans; Hydrocephalus; Male; Sub | 2011 |
Antifibrinolytic in subarachnoid hemorrhage.
Topics: Aminocaproic Acid; Antifibrinolytic Agents; Brain Ischemia; Female; Humans; Hydrocephalus; Male; Sub | 2011 |
ε-Aminocaproic acid in angiographically negative subarachnoid hemorrhage patients is safe: a retrospective review of 83 consecutive patients.
Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Brain Ischemia; Case-Control Studies; Cerebral An | 2012 |
An examination of aneurysm rerupture rates with epsilon aminocaproic acid.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aminocaproic Acid; Aneurysm, Ruptured; Antifibrinolytic | 2013 |