Page last updated: 2024-10-17

aminocaproic acid and Brain Edema

aminocaproic acid has been researched along with Brain Edema in 5 studies

Aminocaproic Acid: An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
6-aminohexanoic acid : An epsilon-amino acid comprising hexanoic acid carrying an amino substituent at position C-6. Used to control postoperative bleeding, and to treat overdose effects of the thrombolytic agents streptokinase and tissue plasminogen activator.

Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)

Research Excerpts

ExcerptRelevanceReference
" Further studies are needed to clarify optimal therapeutic dosing and to identify mechanisms of neuroprotection in rat SBI models."1.43Epsilon Aminocaproic Acid Pretreatment Provides Neuroprotection Following Surgically Induced Brain Injury in a Rat Model. ( Applegate, RL; Khatibi, N; Komanapalli, ES; Martin, RD; Rolland, W; Sherchan, P; Tang, J; Zhang, JH, 2016)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jeong, HG1
Cha, BG1
Kang, DW1
Kim, DY1
Ki, SK1
Kim, SI1
Han, JH1
Yang, W1
Kim, CK1
Kim, J1
Lee, SH1
Komanapalli, ES1
Sherchan, P1
Rolland, W1
Khatibi, N1
Martin, RD1
Applegate, RL1
Tang, J2
Zhang, JH2
Yang, P1
Manaenko, A1
Xu, F1
Miao, L1
Wang, G1
Hu, X1
Guo, ZN1
Hu, Q1
Hartman, RE1
Pearce, WJ1
Obenaus, A1
Chen, G1
Peerless, SJ1
Langtitt, TW1

Other Studies

5 other studies available for aminocaproic acid and Brain Edema

ArticleYear
Ceria Nanoparticles Synthesized With Aminocaproic Acid for the Treatment of Subarachnoid Hemorrhage.
    Stroke, 2018, Volume: 49, Issue:12

    Topics: Aminocaproic Acid; Animals; Anti-Inflammatory Agents; Brain; Brain Edema; Cell Death; Cerium; In Sit

2018
Epsilon Aminocaproic Acid Pretreatment Provides Neuroprotection Following Surgically Induced Brain Injury in a Rat Model.
    Acta neurochirurgica. Supplement, 2016, Volume: 121

    Topics: Aminocaproic Acid; Animals; Antifibrinolytic Agents; Behavior, Animal; Brain; Brain Edema; Brain Inj

2016
Role of PDGF-D and PDGFR-β in neuroinflammation in experimental ICH mice model.
    Experimental neurology, 2016, Volume: 283, Issue:Pt A

    Topics: Aminocaproic Acid; Animals; Basal Ganglia; Brain Edema; Cerebral Hemorrhage; Disease Models, Animal;

2016
Pre- and postoperative management of cerebral aneurysms.
    Clinical neurosurgery, 1979, Volume: 26

    Topics: Aminocaproic Acid; Brain Edema; Humans; Hydrocephalus; Hypertension; Intracranial Aneurysm; Ischemic

1979
Conservative care of intracranial hemorrhage.
    Advances in neurology, 1977, Volume: 16

    Topics: Aminocaproic Acid; Blood Pressure; Brain Edema; Cerebral Hemorrhage; Humans; Hydrocephalus; Hyperton

1977