Page last updated: 2024-10-17

aminocaproic acid and Body Weight

aminocaproic acid has been researched along with Body Weight in 8 studies

Aminocaproic Acid: An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
6-aminohexanoic acid : An epsilon-amino acid comprising hexanoic acid carrying an amino substituent at position C-6. Used to control postoperative bleeding, and to treat overdose effects of the thrombolytic agents streptokinase and tissue plasminogen activator.

Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.

Research Excerpts

ExcerptRelevanceReference
" Although plasma EACA concentrations greater than 130 microg/mL were consistently achieved, we observed a marked variability (more than sixfold) in plasma concentrations and bleeding outcomes despite the use of a weight-based dosing regimen."1.30epsilon-Aminocaproic acid plasma levels during cardiopulmonary bypass. ( Ayuso, L; Bennett-Guerrero, E; Canada, AT; Mythen, MG; Newman, MF; Reves, JG; Sorohan, JG, 1997)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19904 (50.00)18.7374
1990's2 (25.00)18.2507
2000's1 (12.50)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Stricker, PA1
Zuppa, AF1
Fiadjoe, JE1
Maxwell, LG1
Sussman, EM1
Pruitt, EY1
Goebel, TK1
Gastonguay, MR1
Taylor, JA1
Bartlett, SP1
Schreiner, MS1
KWAAN, HC1
ASTRUP, T1
Yamaguchi, M1
Uchiyama, S1
Smith, ME1
Amaducci, LA1
Bennett-Guerrero, E1
Sorohan, JG1
Canada, AT1
Ayuso, L1
Newman, MF1
Reves, JG1
Mythen, MG1
MacIomhair, M1
Lavelle, SM1
Conley, BA1
Sewack, GF1
Egorin, MJ1
Subramanyam, B1
Page, JG1
Grieshaber, CK1
Hirose, M1
Inoue, T1
Masuda, A1
Tsuda, H1
Ito, N1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy of ε-Aminocaproic Acid (EACA) in Children Undergoing Craniofacial Reconstruction Surgery[NCT02229968]Phase 222 participants (Actual)Interventional2014-10-31Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for aminocaproic acid and Body Weight

ArticleYear
Population pharmacokinetics of epsilon-aminocaproic acid in infants undergoing craniofacial reconstruction surgery.
    British journal of anaesthesia, 2013, Volume: 110, Issue:5

    Topics: Age Factors; Aminocaproic Acid; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Bo

2013

Other Studies

7 other studies available for aminocaproic acid and Body Weight

ArticleYear
AORTIC ARTERIOSCLEROSIS IN RABBITS. FED INHIBITORS OF FIBRINOLYSIS.
    Archives of pathology, 1964, Volume: 78

    Topics: Aminocaproates; Aminocaproic Acid; Aortic Aneurysm; Aortic Diseases; Arachis; Arteriosclerosis; Body

1964
Preventive effect of zinc acexamate administration in streptozotocin-diabetic rats: Restoration of bone loss.
    International journal of molecular medicine, 2003, Volume: 12, Issue:5

    Topics: Alkaline Phosphatase; Aminocaproates; Aminocaproic Acid; Animal Feed; Animals; Body Weight; Bone and

2003
Observations on the effects of protease inhibitors on the suppression of experimental allergic encephalomyelitis.
    Neurochemical research, 1982, Volume: 7, Issue:5

    Topics: Aminocaproic Acid; Animals; Anthraquinones; Benzoates; Body Weight; Encephalomyelitis, Autoimmune, E

1982
epsilon-Aminocaproic acid plasma levels during cardiopulmonary bypass.
    Anesthesia and analgesia, 1997, Volume: 85, Issue:2

    Topics: Aged; Aminocaproic Acid; Antifibrinolytic Agents; Body Weight; Cardiopulmonary Bypass; Chest Tubes;

1997
Thrombus weight as a measure of hypercoagulability induced by drugs.
    Thrombosis and haemostasis, 1979, Oct-31, Volume: 42, Issue:3

    Topics: Adenosine Diphosphate; Aging; Aminocaproates; Aminocaproic Acid; Animals; Benzopyrans; Blood Coagula

1979
The effect of the monoamine oxidase inhibitor isocarboxazid on the canine metabolism of the cell-differentiating agent hexamethylene bisacetamide.
    Cancer chemotherapy and pharmacology, 1991, Volume: 28, Issue:1

    Topics: Acetamides; Administration, Oral; Aminocaproates; Aminocaproic Acid; Animals; Body Weight; Chromatog

1991
Effects of simultaneous treatment with various chemicals on BHA-induced development of rat forestomach hyperplasia--complete inhibition by diethylmaleate in a 5-week feeding study.
    Carcinogenesis, 1987, Volume: 8, Issue:10

    Topics: Aminocaproic Acid; Animals; Body Weight; Butylated Hydroxyanisole; Dexamethasone; Diet; Diterpenes;

1987