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aminocaproic acid and Blunt Injuries

aminocaproic acid has been researched along with Blunt Injuries in 10 studies

Aminocaproic Acid: An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
6-aminohexanoic acid : An epsilon-amino acid comprising hexanoic acid carrying an amino substituent at position C-6. Used to control postoperative bleeding, and to treat overdose effects of the thrombolytic agents streptokinase and tissue plasminogen activator.

Research Excerpts

ExcerptRelevanceReference
"The purpose of this study is to determine the incidence of secondary hemorrhage after traumatic hyphema in children and to evaluate the efficacy of epsilon aminocaproic acid in reducing this incidence."9.08Clinical evaluation of aminocaproic acid for managing traumatic hyphema in children. ( Barsoum-Homsy, M; Brunette, I; Chevrette, L; Jacob, JL; Milot, J; Orquin, J; Polomeno, RC; Quigley, MG; Teboul, BK, 1995)
"To determine whether topically applied aminocaproic acid, like systemic aminocaproic acid, effectively reduces secondary hemorrhage after hyphemas and to compare the safety and effectiveness of topical application with those of systemic use and a control group."9.08Topical aminocaproic acid in the treatment of traumatic hyphema. ( Chames, M; Crouch, ER; Gray, MK; Williams, PB, 1997)
"Fifty-nine patients who sustained hyphema following blunt trauma were randomly assigned prospectively to either of two dose regimens of epsilon aminocaproic acid (Amicar)."9.06A comparison of two dose regimens of epsilon aminocaproic acid in the prevention and management of secondary traumatic hyphemas. ( Anderson, RJ; Fiscella, R; Frenkel, M; Goldberg, MF; Palmer, DJ, 1986)
"The purpose of this study is to determine the incidence of secondary hemorrhage after traumatic hyphema in children and to evaluate the efficacy of epsilon aminocaproic acid in reducing this incidence."5.08Clinical evaluation of aminocaproic acid for managing traumatic hyphema in children. ( Barsoum-Homsy, M; Brunette, I; Chevrette, L; Jacob, JL; Milot, J; Orquin, J; Polomeno, RC; Quigley, MG; Teboul, BK, 1995)
"To determine whether topically applied aminocaproic acid, like systemic aminocaproic acid, effectively reduces secondary hemorrhage after hyphemas and to compare the safety and effectiveness of topical application with those of systemic use and a control group."5.08Topical aminocaproic acid in the treatment of traumatic hyphema. ( Chames, M; Crouch, ER; Gray, MK; Williams, PB, 1997)
"Fifty-nine patients who sustained hyphema following blunt trauma were randomly assigned prospectively to either of two dose regimens of epsilon aminocaproic acid (Amicar)."5.06A comparison of two dose regimens of epsilon aminocaproic acid in the prevention and management of secondary traumatic hyphemas. ( Anderson, RJ; Fiscella, R; Frenkel, M; Goldberg, MF; Palmer, DJ, 1986)
" Although evidence was limited, it appears that people with traumatic hyphema who receive aminocaproic acid or tranexamic acid are less likely to experience secondary hemorrhaging."5.01Medical interventions for traumatic hyphema. ( Gharaibeh, A; Goldberg, MF; Lindsley, K; Savage, HI; Scherer, RW, 2019)
"Traumatic hyphema is the entry of blood into the anterior chamber (the space between the cornea and iris) subsequent to a blow or a projectile striking the eye."2.49Medical interventions for traumatic hyphema. ( Gharaibeh, A; Goldberg, MF; Lindsley, K; Savage, HI; Scherer, RW, 2013)
"Traumatic hyphema is the entry of blood into the anterior chamber (the space between the cornea and iris) subsequent to a blow or a projectile striking the eye."2.47Medical interventions for traumatic hyphema. ( Gharaibeh, A; Goldberg, MF; Lindsley, K; Savage, HI; Scherer, RW, 2011)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19902 (20.00)18.7374
1990's4 (40.00)18.2507
2000's1 (10.00)29.6817
2010's3 (30.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gharaibeh, A3
Savage, HI3
Scherer, RW3
Goldberg, MF5
Lindsley, K3
Wilker, SC1
Singh, A1
Ellis, FJ1
Teboul, BK1
Jacob, JL1
Barsoum-Homsy, M1
Brunette, I1
Chevrette, L1
Milot, J1
Orquin, J1
Polomeno, RC1
Quigley, MG1
Crouch, ER2
Williams, PB1
Gray, MK1
Chames, M1
Shiuey, Y1
Lucarelli, MJ1
Johnstone, BR1
Syme, RR1
Palmer, DJ1
Frenkel, M1
Fiscella, R1
Anderson, RJ1

Reviews

3 reviews available for aminocaproic acid and Blunt Injuries

ArticleYear
Medical interventions for traumatic hyphema.
    The Cochrane database of systematic reviews, 2019, 01-14, Volume: 1

    Topics: Adrenal Cortex Hormones; Aminocaproic Acid; Antifibrinolytic Agents; Aspirin; Bandages; Bed Rest; Ch

2019
Medical interventions for traumatic hyphema.
    The Cochrane database of systematic reviews, 2013, Dec-03, Issue:12

    Topics: Adrenal Cortex Hormones; Aminocaproic Acid; Antifibrinolytic Agents; Aspirin; Bandages; Bed Rest; Es

2013
Medical interventions for traumatic hyphema.
    The Cochrane database of systematic reviews, 2011, Jan-19, Issue:1

    Topics: Adrenal Cortex Hormones; Aminocaproic Acid; Antifibrinolytic Agents; Aspirin; Bandages; Bed Rest; Es

2011

Trials

3 trials available for aminocaproic acid and Blunt Injuries

ArticleYear
Clinical evaluation of aminocaproic acid for managing traumatic hyphema in children.
    Ophthalmology, 1995, Volume: 102, Issue:11

    Topics: Administration, Oral; Aminocaproic Acid; Antifibrinolytic Agents; Child; Double-Blind Method; Eye In

1995
Topical aminocaproic acid in the treatment of traumatic hyphema.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1997, Volume: 115, Issue:9

    Topics: Administration, Topical; Adult; Aminocaproic Acid; Anterior Eye Segment; Antifibrinolytic Agents; Do

1997
A comparison of two dose regimens of epsilon aminocaproic acid in the prevention and management of secondary traumatic hyphemas.
    Ophthalmology, 1986, Volume: 93, Issue:1

    Topics: Administration, Topical; Adolescent; Adrenal Cortex Hormones; Adult; Aminocaproates; Aminocaproic Ac

1986

Other Studies

4 other studies available for aminocaproic acid and Blunt Injuries

ArticleYear
Recurrent bleeding following traumatic hyphema due to mild hemophilia B (Christmas disease).
    Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2007, Volume: 11, Issue:6

    Topics: Aminocaproic Acid; Anterior Eye Segment; Antifibrinolytic Agents; Child; Eye Injuries; Hemophilia B;

2007
The treatment of traumatic hyphema with topical epsilon-aminocaproic acid.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1997, Volume: 115, Issue:9

    Topics: Administration, Topical; Aminocaproic Acid; Anterior Eye Segment; Antifibrinolytic Agents; Eye Injur

1997
Traumatic hyphema and patient outcomes--an oversight.
    Ophthalmology, 1998, Volume: 105, Issue:12

    Topics: Ambulatory Care; Aminocaproic Acid; Anterior Eye Segment; Eye Injuries; Humans; Hyphema; Recurrence;

1998
Myonecrosis complicating epsilon aminocaproic acid treatment of traumatic haematuria.
    British journal of urology, 1987, Volume: 60, Issue:1

    Topics: Adult; Aminocaproates; Aminocaproic Acid; Athletic Injuries; Hematuria; Humans; Kidney; Male; Muscle

1987