aminocaproic acid has been researched along with Anti-Glomerular Basement Membrane Disease in 1 studies
Aminocaproic Acid: An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
6-aminohexanoic acid : An epsilon-amino acid comprising hexanoic acid carrying an amino substituent at position C-6. Used to control postoperative bleeding, and to treat overdose effects of the thrombolytic agents streptokinase and tissue plasminogen activator.
Anti-Glomerular Basement Membrane Disease: An autoimmune disease of the KIDNEY and the LUNG. It is characterized by the presence of circulating autoantibodies targeting the epitopes in the non-collagenous domains of COLLAGEN TYPE IV in the basement membranes of kidney glomeruli (KIDNEY GLOMERULUS) and lung alveoli (PULMONARY ALVEOLI), and the subsequent destruction of these basement membranes. Clinical features include pulmonary alveolar hemorrhage and glomerulonephritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The hydroxyproline release assay was used to quantitate degradation of rat GBM in vitro by leukocyte proteinases stimulated by phorbol myristate acetate (PMA), in the presence or absence of EACA and aprotinin." | 1.31 | Mechanism of antinephritic effect of proteinase inhibitors in experimental anti-GBM glomerulopathy. ( Hruby, Z; Kopeć, W; Paczek, L; Soin, J; Wendycz, D; Zieliński, B, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hruby, Z | 1 |
| Wendycz, D | 1 |
| Kopeć, W | 1 |
| Zieliński, B | 1 |
| Paczek, L | 1 |
| Soin, J | 1 |
1 other study available for aminocaproic acid and Anti-Glomerular Basement Membrane Disease
| Article | Year |
|---|---|
Mechanism of antinephritic effect of proteinase inhibitors in experimental anti-GBM glomerulopathy.
Topics: Aminocaproic Acid; Animals; Anti-Glomerular Basement Membrane Disease; Aprotinin; Basement Membrane; | 2000 |