Page last updated: 2024-10-17

aminocaproic acid and Angioneurotic Edema

aminocaproic acid has been researched along with Angioneurotic Edema in 23 studies

Aminocaproic Acid: An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
6-aminohexanoic acid : An epsilon-amino acid comprising hexanoic acid carrying an amino substituent at position C-6. Used to control postoperative bleeding, and to treat overdose effects of the thrombolytic agents streptokinase and tissue plasminogen activator.

Research Excerpts

ExcerptRelevanceReference
" A combination of aprotinin with tranexamic acid may be effective in preventing or delaying rebleeding after rupture of an intracerebral aneurysm; the addition of aprotinin seems to decrease the incidence of delayed cerebral vasospasm and ischaemic complications which are sometimes noted when tranexamic acid alone is used."4.77Clinical application of inhibitors of fibrinolysis. ( Verstraete, M, 1985)
"The acquired angioedema is the most frequently the effect of lymphoproliferative and autoimmunological diseases."2.43[Hereditary angioedema in a 16-year-old girl]. ( Kasznia-Kocot, J; Kordys-Darmolińska, B; Kozowicz, M; Kwaśniak, A; Woś, H; Zukowska, B, 2006)
"Hereditary angioedema is characterized by recurrent attacks of painless, non itching edema of the face and limbs and sometimes by abdominal symptoms."1.27[Hereditary angioedema. A hereditary disorder in the synthesis of the complement system]. ( Vander Eecken, P; Vanderstock, L; Vermeersch, H, 1983)
"Hereditary angioneurotic edema, although a rare clinical entity, can be fatal if diagnosis and appropriate therapy are not instituted before the performance of routine dental and oral surgical procedures."1.26Hereditary angioneurotic edema: clinical management and case report. ( Jankowski, R; Licari, G; Mauro, JV; Meyrowitz, MR, 1982)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199014 (60.87)18.7374
1990's3 (13.04)18.2507
2000's6 (26.09)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Farkas, H1
Harmat, G1
Füst, G1
Varga, L1
Visy, B1
EISEN, V1
Zuraw, BL1
Ritchie, BC1
Frank, MM1
Kozowicz, M1
Kordys-Darmolińska, B1
Kasznia-Kocot, J1
Woś, H1
Zukowska, B1
Kwaśniak, A1
Pedraz, J1
Daudén, E1
García-Diez, A1
Mauro, JV1
Meyrowitz, MR1
Licari, G1
Jankowski, R1
Guerrero, M1
Prieto, L1
Basomba, A1
Campos, A1
Peláez, A1
García Villalmanzo, I1
Brickman, CM1
Hosea, SW1
Sawicka, B1
Zawisza, E1
Pezko, H1
Vanderstock, L1
Vander Eecken, P1
Vermeersch, H1
Donaldson, VH1
Van Dellen, RG1
Dérer, M1
Hegyi, E1
Hauptmann, G1
Mayer, S1
Vierling, F1
Barats, JC1
Roger, S1
Hamilton, AG1
Bosley, AR1
Bowen, DJ1
Frank, M1
Gelfand, JA1
Alling, DW1
Sherins, RJ1
Madaliński, K2
Sabbouh, K2
Chorazykiewicz, M2
Gregorek, H1
Imielska, D1
Verstraete, M1
Reich, P1
Kramer, J1
Bork, K1
Alsenz, J1
Böckers, M1
Noah, E1
Loos, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy in Controlling Bleeding Post-coronary Bypass Surgery Using Combination of Local Application of Tranexamic Acid and Intravenous Tranexamic Compared to Intravenous Tranexamic Acid Alone. A Randomized Controlled Trial[NCT01600599]40 participants (Actual)Interventional2011-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

8 reviews available for aminocaproic acid and Angioneurotic Edema

ArticleYear
Clinical management of hereditary angio-oedema in children.
    Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 2002, Volume: 13, Issue:3

    Topics: Adolescent; Aminocaproic Acid; Angioedema; Child; Child, Preschool; Complement C1 Inactivator Protei

2002
FIBRINOLYSIS AND FORMATION OF BIOLOGICALLY ACTIVE POLYPEPTIDES.
    British medical bulletin, 1964, Volume: 20

    Topics: Alpha-Globulins; Aminocaproates; Aminocaproic Acid; Anaphylaxis; Angioedema; Blood Coagulation Facto

1964
Protease inhibitors in the treatment of hereditary angioedema.
    Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis, 2003, Volume: 29, Issue:3

    Topics: Aminocaproic Acid; Angioedema; Antifibrinolytic Agents; Aprotinin; Clinical Trials as Topic; Complem

2003
Hereditary angioedema: the clinical syndrome and its management in the United States.
    Immunology and allergy clinics of North America, 2006, Volume: 26, Issue:4

    Topics: Aminocaproic Acid; Androgens; Angioedema; Antifibrinolytic Agents; Clinical Trials as Topic; Complem

2006
[Hereditary angioedema in a 16-year-old girl].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 2006, Volume: 59, Issue:11-12

    Topics: Adolescent; Aminocaproic Acid; Angioedema; Antifibrinolytic Agents; Complement C1 Inactivator Protei

2006
[Practical management of C1 inhibitor deficiency].
    Actas dermo-sifiliograficas, 2007, Volume: 98, Issue:4

    Topics: Adolescent; Adult; Aminocaproic Acid; Angioedema; Bradykinin; Child; Child, Preschool; Complement C1

2007
Hereditary angioedema.
    International journal of dermatology, 1983, Volume: 22, Issue:3

    Topics: Adult; Aminocaproic Acid; Angioedema; Child; Complement C1 Inactivator Proteins; Danazol; Female; Hu

1983
Clinical application of inhibitors of fibrinolysis.
    Drugs, 1985, Volume: 29, Issue:3

    Topics: 4-Aminobenzoic Acid; Aminocaproic Acid; Angioedema; Antifibrinolytic Agents; Aprotinin; Blood Preser

1985

Other Studies

15 other studies available for aminocaproic acid and Angioneurotic Edema

ArticleYear
Diagnosis and management of hereditary angioedema: an American approach.
    Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis, 2003, Volume: 29, Issue:3

    Topics: Acute Disease; Aminocaproic Acid; Angioedema; Complement C1 Inactivator Proteins; Diagnosis, Differe

2003
Hereditary angioneurotic edema: clinical management and case report.
    Journal of the American Dental Association (1939), 1982, Volume: 104, Issue:5

    Topics: Adult; Aminocaproic Acid; Angioedema; Dental Care for Disabled; Female; Histamine H1 Antagonists; Hu

1982
[Familial angioedema (II). Treatment].
    Medicina clinica, 1984, Jun-02, Volume: 83, Issue:1

    Topics: Aminocaproic Acid; Angioedema; Cinnarizine; Complement C1 Inactivator Proteins; Danazol; Histamine H

1984
[Hemostasis system in patients with Quincke's edema before and after treatment with epsilon-aminocaproic acid].
    Otolaryngologia polska = The Polish otolaryngology, 1984, Volume: 38, Issue:6

    Topics: Adolescent; Adult; Aged; Aminocaproates; Aminocaproic Acid; Angioedema; Female; Hemostasis; Humans;

1984
[Hereditary angioedema. A hereditary disorder in the synthesis of the complement system].
    Acta oto-rhino-laryngologica Belgica, 1983, Volume: 36, Issue:3

    Topics: Adult; Aminocaproic Acid; Angioedema; Complement Activation; Complement C1 Inactivator Proteins; Com

1983
Plasminogen activation in hereditary angioneurotic edema.
    The Journal of laboratory and clinical medicine, 1993, Volume: 121, Issue:1

    Topics: Aminocaproic Acid; Angioedema; Complement System Proteins; Fibrinolysin; Humans; Plasminogen; Plasmi

1993
Long-term treatment of C1 inhibitor deficiency with epsilon-aminocaproic acid in two patients.
    Mayo Clinic proceedings, 1996, Volume: 71, Issue:12

    Topics: Adult; Aminocaproic Acid; Angioedema; Antifibrinolytic Agents; Complement C1 Inactivator Proteins; F

1996
[Hereditary angioedema in three members of one family (author's transl)].
    Bratislavske lekarske listy, 1979, Volume: 71, Issue:6

    Topics: Adult; Aminocaproic Acid; Angioedema; Child; Female; Humans; Male

1979
[Hereditary angioneurotic oedema: preoperative prophylactic therapy with danazol].
    La Nouvelle presse medicale, 1978, Sep-30, Volume: 7, Issue:33

    Topics: Adult; Aminocaproic Acid; Angioedema; Complement C1 Inactivator Proteins; Complement C4; Danazol; Fe

1978
Laryngeal oedema due to hereditary angioedema.
    Anaesthesia, 1977, Volume: 32, Issue:3

    Topics: Adult; Airway Obstruction; Aminocaproic Acid; Angioedema; Exchange Transfusion, Whole Blood; Humans;

1977
Epsilon aminocaproic acid for hereditary angioedema.
    The New England journal of medicine, 1977, May-26, Volume: 296, Issue:21

    Topics: Aminocaproates; Aminocaproic Acid; Angioedema; Humans

1977
C1-INH defect as an example of deficiency disease.
    Immunological investigations, 1991, Volume: 20, Issue:2

    Topics: Adolescent; Adult; Aged; Aminocaproic Acid; Angioedema; Child; Child, Preschool; Complement C1 Inact

1991
Familial occurrence of C1-inhibitor deficiency and the effect of treatment.
    Archivum immunologiae et therapiae experimentalis, 1989, Volume: 37, Issue:5-6

    Topics: Adolescent; Aminocaproic Acid; Androgens; Angioedema; Child; Complement C1 Inactivator Proteins; Fem

1989
[Andrologic aspects of the therapy of hereditary angioneurotic edema].
    Dermatologische Monatschrift, 1986, Volume: 172, Issue:1

    Topics: Adult; Aminocaproates; Aminocaproic Acid; Angioedema; Danazol; Humans; Male; Oligospermia; Pregnadie

1986
[Formation of IgG antibodies to C1 inhibitor as the cause of life-threatening angioedema].
    Deutsche medizinische Wochenschrift (1946), 1987, Mar-27, Volume: 112, Issue:13

    Topics: Adult; Aminocaproic Acid; Angioedema; Complement C1; Complement C1 Inactivator Proteins; Complement

1987