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aminocaproic acid and Acute Kidney Failure

aminocaproic acid has been researched along with Acute Kidney Failure in 13 studies

Aminocaproic Acid: An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
6-aminohexanoic acid : An epsilon-amino acid comprising hexanoic acid carrying an amino substituent at position C-6. Used to control postoperative bleeding, and to treat overdose effects of the thrombolytic agents streptokinase and tissue plasminogen activator.

Research Excerpts

ExcerptRelevanceReference
"We conducted a secondary analysis of the MAssive Transfusion in Children (MATIC), a prospectively collected database of children with life-threatening hemorrhage (LTH), and evaluated for risk of adverse events with either antifibrinolytic treatment, epsilon aminocaproic acid (EACA) or tranexamic acid (TXA)."8.31Epsilon aminocaproic acid is associated with acute kidney injury after life-threatening hemorrhage in children. ( Josephson, CD; Kolodziej, JH; Leeper, CM; Leonard, JC; Spinella, PC; Zenati, MS, 2023)
"We conducted a secondary analysis of the MAssive Transfusion in Children (MATIC), a prospectively collected database of children with life-threatening hemorrhage (LTH), and evaluated for risk of adverse events with either antifibrinolytic treatment, epsilon aminocaproic acid (EACA) or tranexamic acid (TXA)."4.31Epsilon aminocaproic acid is associated with acute kidney injury after life-threatening hemorrhage in children. ( Josephson, CD; Kolodziej, JH; Leeper, CM; Leonard, JC; Spinella, PC; Zenati, MS, 2023)
"To examine the role of epsilon-aminocaproic acid (EACA) administered after reperfusion of the donor liver in the incidences of thromboembolic events and acute kidney injury within 30 days after orthotopic liver transplantation."3.83Epsilon-Aminocaproic Acid Has No Association With Thromboembolic Complications, Renal Failure, or Mortality After Liver Transplantation. ( Bohorquez, HE; Bruce, DS; Carmody, IC; Cohen, AJ; Daly, WJ; Evans, BM; Fish, B; Ganier, DR; Gitman, M; Koveleskie, J; Ku, TC; Loss, GE; Marshall, T; Nicolau-Raducu, R; Nossaman, BD; Reichman, TW, 2016)
"An 18-year-old man with mild factor VIII deficiency developed hematuria and, subsequently, acute renal failure due to high-grade urinary obstruction by clots during therapy with cryoprecipitate, epsilon-aminocaproic acid, and acetazolamide administered for ocular trauma."3.67Acute renal failure due to high-grade obstruction following therapy with epsilon-aminocaproic acid. ( Bontempo, FA; Greenberg, A; Pitts, TO; Spero, JA, 1986)
"It can also be used to treat hematuria through its action on decreasing urinary fibrinolysis."2.41Epsilon-aminocaproic acid and renal complications: case report and review of the literature. ( Fozailoff, A; Manjunath, G; Mitcheson, D; Sarnak, MJ, 2002)
" Thus, pharmacokinetic changes in rats with acute renal failure induced by uranyl nitrate (U-ARF rats) were investigated in this study."1.38Reduced clearance of ε-acetamidocaproic acid in rats with acute renal failure induced by uranyl nitrate. ( Choi, YH; Han, SY; Lee, MG; Yang, SH; Yoon, I, 2012)
"The acute renal failure was treated conservatively, and the patient recovered 12 days after the snake bite and discharged from hospital with no sequelae."1.26Afibrinogenemia following snake bite (Crotalus durissus terrificus). ( Amaral, CF; da Silva, OA; López, M; Pedroso, ER, 1980)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19905 (38.46)18.7374
1990's1 (7.69)18.2507
2000's2 (15.38)29.6817
2010's3 (23.08)24.3611
2020's2 (15.38)2.80

Authors

AuthorsStudies
Kolodziej, JH1
Leeper, CM1
Leonard, JC1
Josephson, CD1
Zenati, MS1
Spinella, PC1
Butt, AL1
Stewart, KE1
Kyo, H1
Tanaka, KA1
Nicolau-Raducu, R1
Ku, TC1
Ganier, DR1
Evans, BM1
Koveleskie, J1
Daly, WJ1
Fish, B1
Cohen, AJ1
Reichman, TW1
Bohorquez, HE1
Bruce, DS1
Carmody, IC1
Loss, GE1
Gitman, M1
Marshall, T1
Nossaman, BD1
Mutter, WP1
Stillman, IE1
Dahl, NK1
Leyvi, G1
Nelson, O1
Yedlin, A1
Pasamba, M1
Belamarich, PF1
Nair, S1
Cohen, HW1
Han, SY1
Yang, SH1
Yoon, I1
Lee, MG1
Choi, YH1
Manjunath, G1
Fozailoff, A1
Mitcheson, D1
Sarnak, MJ1
LAGRUE, G1
MILLIEZ, P1
Heldrich, FJ1
Salcedo, UT1
Salcedo, JR1
Herrera, AJ1
Biswas, CK1
Milligan, DA1
Agte, SD1
Kenward, DH1
Tilley, PJ1
Amaral, CF1
da Silva, OA1
López, M1
Pedroso, ER1
Biriukova, LS1
Gumin, LM1
Gorodetskiĭ, VM1
Pitts, TO1
Spero, JA1
Bontempo, FA1
Greenberg, A1

Reviews

2 reviews available for aminocaproic acid and Acute Kidney Failure

ArticleYear
Epsilon-aminocaproic acid and renal complications: case report and review of the literature.
    Clinical nephrology, 2002, Volume: 58, Issue:1

    Topics: Acute Kidney Injury; Aged; Aminocaproic Acid; Antifibrinolytic Agents; Creatinine; Female; Hematuria

2002
[NEPHROLOGY IN 1964].
    La Revue du praticien, 1964, Jun-21, Volume: 14

    Topics: Acute Kidney Injury; Aminocaproates; Aminocaproic Acid; Antineoplastic Agents; Diabetes Mellitus; Di

1964

Other Studies

11 other studies available for aminocaproic acid and Acute Kidney Failure

ArticleYear
Epsilon aminocaproic acid is associated with acute kidney injury after life-threatening hemorrhage in children.
    Transfusion, 2023, Volume: 63 Suppl 3

    Topics: Acute Kidney Injury; Adolescent; Aminocaproic Acid; Antifibrinolytic Agents; Blood Loss, Surgical; C

2023
In response: Approaching risk assessment with caution: Epsilon aminocaproic acid and acute kidney injury in the secondary analysis.
    Transfusion, 2023, Volume: 63, Issue:11

    Topics: Acute Kidney Injury; Aminocaproic Acid; Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Risk

2023
Epsilon-Aminocaproic Acid Has No Association With Thromboembolic Complications, Renal Failure, or Mortality After Liver Transplantation.
    Journal of cardiothoracic and vascular anesthesia, 2016, Volume: 30, Issue:4

    Topics: Acute Kidney Injury; Aminocaproic Acid; Antifibrinolytic Agents; Dose-Response Relationship, Drug; F

2016
Thrombotic microangiopathy and renal failure exacerbated by epsilon-aminocaproic acid.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2009, Volume: 53, Issue:2

    Topics: Acute Kidney Injury; Aminocaproic Acid; Antifibrinolytic Agents; Antiphospholipid Syndrome; Female;

2009
A comparison of the effect of aprotinin and ε-aminocaproic acid on renal function in children undergoing cardiac surgery.
    Journal of cardiothoracic and vascular anesthesia, 2011, Volume: 25, Issue:3

    Topics: Acute Kidney Injury; Age Factors; Aminocaproic Acid; Aprotinin; Cardiac Surgical Procedures; Child;

2011
Reduced clearance of ε-acetamidocaproic acid in rats with acute renal failure induced by uranyl nitrate.
    The Journal of pharmacy and pharmacology, 2012, Volume: 64, Issue:10

    Topics: Acute Kidney Injury; Administration, Oral; Aminocaproates; Aminocaproic Acid; Animals; Area Under Cu

2012
Aminocaproic acid (EACA) therapy for neonatal post-renal biopsy bleeding with renal failure.
    Maryland state medical journal, 1982, Volume: 31, Issue:7

    Topics: Acute Kidney Injury; Aminocaproates; Aminocaproic Acid; Biopsy, Needle; Female; Hematuria; Humans; I

1982
Acute renal failure and myopathy after treatment with aminocaproic acid.
    British medical journal, 1980, Jul-12, Volume: 281, Issue:6233

    Topics: Acute Kidney Injury; Adult; Aminocaproates; Aminocaproic Acid; Aspartate Aminotransferases; Creatine

1980
Afibrinogenemia following snake bite (Crotalus durissus terrificus).
    The American journal of tropical medicine and hygiene, 1980, Volume: 29, Issue:6

    Topics: Acute Kidney Injury; Afibrinogenemia; Aminocaproic Acid; Blood Coagulation Tests; Brazil; Child; Cro

1980
[Acute kidney failure due to obstruction of the upper urinary tract during the use of aminocaproic acid].
    Terapevticheskii arkhiv, 1993, Volume: 65, Issue:7

    Topics: Acute Kidney Injury; Adolescent; Aminocaproic Acid; Combined Modality Therapy; Drug Therapy, Combina

1993
Acute renal failure due to high-grade obstruction following therapy with epsilon-aminocaproic acid.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1986, Volume: 8, Issue:6

    Topics: Acute Kidney Injury; Adolescent; Aminocaproates; Aminocaproic Acid; Blood Coagulation; Hematuria; He

1986