aminocaproic acid has been researched along with Acrocephaly in 6 studies
Aminocaproic Acid: An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
6-aminohexanoic acid : An epsilon-amino acid comprising hexanoic acid carrying an amino substituent at position C-6. Used to control postoperative bleeding, and to treat overdose effects of the thrombolytic agents streptokinase and tissue plasminogen activator.
Acrocephaly: Premature closing of the lambdoid and coronal sutures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This multicenter international experience of pediatric craniofacial surgery reports no increase in seizures or thromboembolic events in those that received antifibrinolytics (tranexamic acid and epsilon-aminocaproic acid) versus those that did not." | 4.12 | Safety of antifibrinolytics in 6583 pediatric patients having craniosynostosis surgery: A decade of data reported from the multicenter Pediatric Craniofacial Collaborative Group. ( Benzon, HA; Goobie, SM; King, MR; Nelson, O; Pérez-Pradilla, C; Staffa, SJ; Stricker, PA, 2022) |
| " Current dosing recommendations are derived from adult extrapolations, and may or may not have clinical relevance." | 1.46 | Blood loss and transfusion requirements with epsilon-aminocaproic acid use during cranial vault reconstruction surgery. ( Demke, J; Nagy, L; Saadeh, C; Thompson, ME; Watkins, P, 2017) |
| "Aminocaproic acid (ACA) has been used at our institution during CVR for its antifibrinolytic effects." | 1.40 | Minimizing transfusions in primary cranial vault remodeling: the role of aminocaproic acid. ( Buchman, SR; Kapurch, J; Levi, B; Muraszko, KM; Oppenheimer, AJ; Ranganathan, K; Strahle, JM, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 3 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| King, MR | 1 |
| Staffa, SJ | 1 |
| Stricker, PA | 1 |
| Pérez-Pradilla, C | 1 |
| Nelson, O | 1 |
| Benzon, HA | 1 |
| Goobie, SM | 1 |
| Pillutla, P | 1 |
| Le, A | 1 |
| Thompson, ME | 2 |
| Watkins, P | 2 |
| Nagy, L | 2 |
| Demke, JC | 1 |
| Borst, AJ | 1 |
| Bonfield, CM | 1 |
| Deenadayalan, PS | 1 |
| Le, CH | 1 |
| Xu, M | 1 |
| Sobey, JH | 1 |
| Reddy, SK | 1 |
| Nguyen, TT | 1 |
| Lam, HV | 1 |
| Austin, TM | 1 |
| Stricker, P | 1 |
| Tunceroglu, H | 1 |
| Schoenecker, J | 1 |
| Oppenheimer, AJ | 1 |
| Ranganathan, K | 1 |
| Levi, B | 1 |
| Strahle, JM | 1 |
| Kapurch, J | 1 |
| Muraszko, KM | 1 |
| Buchman, SR | 1 |
| Saadeh, C | 1 |
| Demke, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy of ε-Aminocaproic Acid (EACA) in Children Undergoing Craniofacial Reconstruction Surgery[NCT02229968] | Phase 2 | 22 participants (Actual) | Interventional | 2014-10-31 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 other studies available for aminocaproic acid and Acrocephaly
| Article | Year |
|---|---|
Safety of antifibrinolytics in 6583 pediatric patients having craniosynostosis surgery: A decade of data reported from the multicenter Pediatric Craniofacial Collaborative Group.
Topics: Aminocaproic Acid; Antifibrinolytic Agents; Blood Loss, Surgical; Child; Craniosynostoses; Humans; I | 2022 |
Dose Comparison of Epsilon-Aminocaproic Acid to Reduce Blood Loss in Infants Undergoing Cranial Vault Reconstruction Surgery: A Retrospective Pilot Study.
Topics: Aminocaproic Acid; Antifibrinolytic Agents; Blood Loss, Surgical; Craniosynostoses; Humans; Infant; | 2020 |
ε-Aminocaproic acid versus tranexamic acid in children undergoing complex cranial vault reconstruction for repair of craniosynostosis.
Topics: Aminocaproic Acid; Antifibrinolytic Agents; Blood Loss, Surgical; Child; Craniosynostoses; Humans; R | 2021 |
Comparison of different dosage regimes of epsilon aminocaproic acid on blood loss in children undergoing craniosynostosis surgery.
Topics: Aminocaproic Acid; Antifibrinolytic Agents; Blood Loss, Surgical; Craniosynostoses; Erythrocyte Tran | 2019 |
Minimizing transfusions in primary cranial vault remodeling: the role of aminocaproic acid.
Topics: Aminocaproic Acid; Antifibrinolytic Agents; Arterial Pressure; Blood Loss, Surgical; Blood Transfusi | 2014 |
Blood loss and transfusion requirements with epsilon-aminocaproic acid use during cranial vault reconstruction surgery.
Topics: Aminocaproic Acid; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Bone Transplant | 2017 |