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aminocaproic acid and Abnormality, Heart

aminocaproic acid has been researched along with Abnormality, Heart in 7 studies

Aminocaproic Acid: An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
6-aminohexanoic acid : An epsilon-amino acid comprising hexanoic acid carrying an amino substituent at position C-6. Used to control postoperative bleeding, and to treat overdose effects of the thrombolytic agents streptokinase and tissue plasminogen activator.

Research Excerpts

ExcerptRelevanceReference
"Excessive postoperative blood loss after cardiopulmonary bypass is a common problem, especially in patients suffering from congenital heart diseases."2.52Epsilon aminocaproic acid reduces blood transfusion and improves the coagulation test after pediatric open-heart surgery: a meta-analysis of 5 clinical trials. ( Li, Q; Lu, J; Meng, H; Meng, Z; Pribis, JP; Sun, Y; Zhu, C, 2015)
" We hypothesized that children would have different pharmacokinetic variables and require a dosing scheme different from adults to maintain stable and effective serum epsilonACA concentrations."1.31The pharmacokinetics of epsilon-aminocaproic acid in children undergoing surgical repair of congenital heart defects. ( Barclay, D; Bennett, J; Butterworth, JF; Hines, MH; James, RL; Lin, YA; O'Brien, JJ; Ririe, DG, 2002)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's0 (0.00)18.2507
2000's4 (57.14)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lu, J1
Meng, H1
Meng, Z1
Sun, Y1
Pribis, JP1
Zhu, C1
Li, Q1
Martin, K1
Gertler, R1
Sterner, A1
MacGuill, M1
Schreiber, C1
Hörer, J1
Vogt, M1
Tassani, P1
Wiesner, G1
TICE, DA1
REED, GE1
CLAUSS, RH1
WORTH, MH1
Chauhan, S3
Das, SN1
Bisoi, A1
Kale, S1
Kiran, U1
Rao, BH2
Saxena, N2
Bisoi, AK1
Venugopal, P2
Kumar, BA1
Rao, MS1
Dubey, B1
Ririe, DG1
James, RL1
O'Brien, JJ1
Lin, YA1
Bennett, J1
Barclay, D1
Hines, MH1
Butterworth, JF1

Reviews

1 review available for aminocaproic acid and Abnormality, Heart

ArticleYear
Epsilon aminocaproic acid reduces blood transfusion and improves the coagulation test after pediatric open-heart surgery: a meta-analysis of 5 clinical trials.
    International journal of clinical and experimental pathology, 2015, Volume: 8, Issue:7

    Topics: Adolescent; Age Factors; Aminocaproic Acid; Antifibrinolytic Agents; Blood Coagulation; Blood Coagul

2015

Trials

3 trials available for aminocaproic acid and Abnormality, Heart

ArticleYear
Comparison of epsilon aminocaproic acid and tranexamic acid in pediatric cardiac surgery.
    Journal of cardiothoracic and vascular anesthesia, 2004, Volume: 18, Issue:2

    Topics: Adolescent; Aminocaproic Acid; Antifibrinolytic Agents; Blood Coagulation Tests; Blood Transfusion;

2004
Epsilon aminocaproic acid in paediatric cardiac surgery to reduce postoperative blood loss.
    The Indian journal of medical research, 2000, Volume: 111

    Topics: Aminocaproic Acid; Blood Loss, Surgical; Child; Coronary Artery Bypass; Heart Defects, Congenital; H

2000
Efficacy of aprotinin, epsilon aminocaproic acid, or combination in cyanotic heart disease.
    The Annals of thoracic surgery, 2000, Volume: 70, Issue:4

    Topics: Adolescent; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Coagulation Tests; Blood Lo

2000

Other Studies

3 other studies available for aminocaproic acid and Abnormality, Heart

ArticleYear
Comparison of blood-sparing efficacy of ε-aminocaproic acid and tranexamic acid in newborns undergoing cardiac surgery.
    The Thoracic and cardiovascular surgeon, 2011, Volume: 59, Issue:5

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgica

2011
HEMORRHAGE DUE TO FIBRINOLYSIS OCCURRING WITH OPEN-HEART OPERATIONS.
    The Journal of thoracic and cardiovascular surgery, 1963, Volume: 46

    Topics: Aminocaproates; Aminocaproic Acid; Aortic Valve Stenosis; Cardiac Surgical Procedures; Child; Enzyme

1963
The pharmacokinetics of epsilon-aminocaproic acid in children undergoing surgical repair of congenital heart defects.
    Anesthesia and analgesia, 2002, Volume: 94, Issue:1

    Topics: Aminocaproic Acid; Anesthesia, General; Cardiopulmonary Bypass; Child, Preschool; Fibrinolytic Agent

2002