aminocaproic acid has been researched along with Abnormality, Heart in 7 studies
Aminocaproic Acid: An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
6-aminohexanoic acid : An epsilon-amino acid comprising hexanoic acid carrying an amino substituent at position C-6. Used to control postoperative bleeding, and to treat overdose effects of the thrombolytic agents streptokinase and tissue plasminogen activator.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Excessive postoperative blood loss after cardiopulmonary bypass is a common problem, especially in patients suffering from congenital heart diseases." | 2.52 | Epsilon aminocaproic acid reduces blood transfusion and improves the coagulation test after pediatric open-heart surgery: a meta-analysis of 5 clinical trials. ( Li, Q; Lu, J; Meng, H; Meng, Z; Pribis, JP; Sun, Y; Zhu, C, 2015) |
| " We hypothesized that children would have different pharmacokinetic variables and require a dosing scheme different from adults to maintain stable and effective serum epsilonACA concentrations." | 1.31 | The pharmacokinetics of epsilon-aminocaproic acid in children undergoing surgical repair of congenital heart defects. ( Barclay, D; Bennett, J; Butterworth, JF; Hines, MH; James, RL; Lin, YA; O'Brien, JJ; Ririe, DG, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lu, J | 1 |
| Meng, H | 1 |
| Meng, Z | 1 |
| Sun, Y | 1 |
| Pribis, JP | 1 |
| Zhu, C | 1 |
| Li, Q | 1 |
| Martin, K | 1 |
| Gertler, R | 1 |
| Sterner, A | 1 |
| MacGuill, M | 1 |
| Schreiber, C | 1 |
| Hörer, J | 1 |
| Vogt, M | 1 |
| Tassani, P | 1 |
| Wiesner, G | 1 |
| TICE, DA | 1 |
| REED, GE | 1 |
| CLAUSS, RH | 1 |
| WORTH, MH | 1 |
| Chauhan, S | 3 |
| Das, SN | 1 |
| Bisoi, A | 1 |
| Kale, S | 1 |
| Kiran, U | 1 |
| Rao, BH | 2 |
| Saxena, N | 2 |
| Bisoi, AK | 1 |
| Venugopal, P | 2 |
| Kumar, BA | 1 |
| Rao, MS | 1 |
| Dubey, B | 1 |
| Ririe, DG | 1 |
| James, RL | 1 |
| O'Brien, JJ | 1 |
| Lin, YA | 1 |
| Bennett, J | 1 |
| Barclay, D | 1 |
| Hines, MH | 1 |
| Butterworth, JF | 1 |
1 review available for aminocaproic acid and Abnormality, Heart
| Article | Year |
|---|---|
Epsilon aminocaproic acid reduces blood transfusion and improves the coagulation test after pediatric open-heart surgery: a meta-analysis of 5 clinical trials.
Topics: Adolescent; Age Factors; Aminocaproic Acid; Antifibrinolytic Agents; Blood Coagulation; Blood Coagul | 2015 |
3 trials available for aminocaproic acid and Abnormality, Heart
| Article | Year |
|---|---|
Comparison of epsilon aminocaproic acid and tranexamic acid in pediatric cardiac surgery.
Topics: Adolescent; Aminocaproic Acid; Antifibrinolytic Agents; Blood Coagulation Tests; Blood Transfusion; | 2004 |
Epsilon aminocaproic acid in paediatric cardiac surgery to reduce postoperative blood loss.
Topics: Aminocaproic Acid; Blood Loss, Surgical; Child; Coronary Artery Bypass; Heart Defects, Congenital; H | 2000 |
Efficacy of aprotinin, epsilon aminocaproic acid, or combination in cyanotic heart disease.
Topics: Adolescent; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Coagulation Tests; Blood Lo | 2000 |
3 other studies available for aminocaproic acid and Abnormality, Heart
| Article | Year |
|---|---|
Comparison of blood-sparing efficacy of ε-aminocaproic acid and tranexamic acid in newborns undergoing cardiac surgery.
Topics: Aminocaproic Acid; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgica | 2011 |
HEMORRHAGE DUE TO FIBRINOLYSIS OCCURRING WITH OPEN-HEART OPERATIONS.
Topics: Aminocaproates; Aminocaproic Acid; Aortic Valve Stenosis; Cardiac Surgical Procedures; Child; Enzyme | 1963 |
The pharmacokinetics of epsilon-aminocaproic acid in children undergoing surgical repair of congenital heart defects.
Topics: Aminocaproic Acid; Anesthesia, General; Cardiopulmonary Bypass; Child, Preschool; Fibrinolytic Agent | 2002 |