Page last updated: 2024-08-21

amiloride and Reperfusion Injury

amiloride has been researched along with Reperfusion Injury in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (23.81)18.2507
2000's12 (57.14)29.6817
2010's4 (19.05)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tai, KK; Truong, DD1
Arreola, J; Kaba, NK; Kim, M; Knauf, PA; Law, FY; Lefort, CT; Martel-Gallegos, G; Schultz, J; Waugh, RE1
Liu, Q; Nakano, K; Osanai, T; Sato, H; Suga, S; Takeo, T; Wakui, M; Wu, J1
Jaggi, AS; Kaur, S; Rehni, AK; Singh, N1
Black, SM; Chakraborty, T; Fakin, RM; Hamacher, J; Hossain, HM; Kumar, S; Lucas, R; Pittet, JF; Roux, J; Schmid, RA; Stammberger, U; Wendel, A; Xiong, C; Yang, G1
Jaggi, AS; Kaur, H; Singh, N1
DiFabio, J; Gori, T; Liuni, A; Luca, MC; Parker, JD1
Chaudhry, A; Chintala, SK; Zhang, X1
ten Hove, M; van Echteld, CJ; van Emous, JG1
Fernández, MA; García, JV; Marina Prendes, MG; Perazzo, JC; Savino, EA; Testoni, G; Varela, A1
Goerge, T; Huck, V; Niemeyer, A; Oberleithner, H; Ossig, R; Rogge, P; Schnaeker, EM; Schneider, MF; Schneider, SW1
Allen, DG; Ju, YK; Williams, IA; Xiao, XH1
Kaneko, K; Kaneshiro, Y; Matsumura, Y; Matsuo, T; Ohkita, M; Takaoka, M; Yamashita, J1
Khimenko, PL; Moore, TM; Taylor, AE1
du Toit, EF; Opie, LH1
Azuma, J; Baba, A; Hashimoto, H; Matsuda, T; Nishiguchi, E; Takuma, K1
Ando, H; Fujita, M; Hotta, Y; Ishikawa, N; Nakagawa, J; Sakakibara, J; Takeya, K1
Estevez, AY; Guyot, LL; O'Regan, MH; Phillis, JW1
Andersson, R; Börjesson, A; Folkesson, HG; Norlin, A; Wang, X1
Hurtado, C; Pierce, GN1
O'Regan, MH; Phillis, JW; Ren, J1

Trials

1 trial(s) available for amiloride and Reperfusion Injury

ArticleYear
The acute administration of either amiloride or captopril does not prevent endothelial dysfunction induced by ischemia and reperfusion in the human forearm vasculature.
    Canadian journal of physiology and pharmacology, 2010, Volume: 88, Issue:10

    Topics: Adult; Amiloride; Angiotensin-Converting Enzyme Inhibitors; Blood Flow Velocity; Captopril; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Endothelium, Vascular; Forearm; Humans; Male; Radial Artery; Reperfusion Injury; Sodium Channel Blockers; Vasodilation; Young Adult

2010

Other Studies

20 other study(ies) available for amiloride and Reperfusion Injury

ArticleYear
Amiloride but not memantine reduces neurodegeneration, seizures and myoclonic jerks in rats with cardiac arrest-induced global cerebral hypoxia and reperfusion.
    PloS one, 2013, Volume: 8, Issue:4

    Topics: Acid Sensing Ion Channels; Amiloride; Animals; Brain Injuries; Heart Arrest; Hypoxia, Brain; Male; Memantine; Myoclonus; Neurons; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reperfusion Injury; Seizures

2013
Inhibition of Na+/H+ exchanger enhances low pH-induced L-selectin shedding and beta2-integrin surface expression in human neutrophils.
    American journal of physiology. Cell physiology, 2008, Volume: 295, Issue:5

    Topics: Amiloride; Ammonium Chloride; CD11b Antigen; CD18 Antigens; Cell Membrane; Guanidines; Humans; Hydrogen-Ion Concentration; L-Selectin; Lactic Acid; Macrophage-1 Antigen; Metalloproteases; Neutrophils; p38 Mitogen-Activated Protein Kinases; Protease Inhibitors; Protein Kinase Inhibitors; Reperfusion Injury; Sodium-Hydrogen Exchangers; Sulfones; Time Factors

2008
Hydrogen peroxide mobilizes Ca2+ through two distinct mechanisms in rat hepatocytes.
    Acta pharmacologica Sinica, 2009, Volume: 30, Issue:1

    Topics: Adenosine Triphosphate; Amiloride; Animals; Calcium; Enzyme Inhibitors; Hepatocytes; Hydrogen Peroxide; Male; Membrane Potential, Mitochondrial; Membrane Potentials; Mitochondria; Oxidants; Oxidation-Reduction; Patch-Clamp Techniques; Rats; Rats, Wistar; Reperfusion Injury; Signal Transduction; Sodium Channel Blockers; Sodium Cyanide; Type C Phospholipases

2009
Studies on cerebral protection of digoxin against ischemia/reperfusion injury in mice.
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2009, Volume: 129, Issue:4

    Topics: Amiloride; Animals; Brain; Brain Ischemia; Calcium; Calcium Signaling; Digoxin; Male; Memory; Mice; Neuroprotective Agents; Psychomotor Performance; Reperfusion Injury; Ruthenium Red; Verapamil

2009
The lectin-like domain of tumor necrosis factor improves lung function after rat lung transplantation--potential role for a reduction in reactive oxygen species generation.
    Critical care medicine, 2010, Volume: 38, Issue:3

    Topics: Alveolar Epithelial Cells; Amiloride; Animals; Disaccharides; Endothelial Cells; Endothelium, Vascular; Lung; Lung Transplantation; Membrane Potentials; Neuropeptides; Oxygen; Pulmonary Alveoli; Rats; Reactive Oxygen Species; Reperfusion Injury; Respiratory Function Tests; Sheep; Sodium Channel Blockers; Superoxides; Tumor Necrosis Factor-alpha

2010
Modulation of neuroprotective effect of ischemic post-conditioning by dichlorobenzamil a Na(+)/Ca(2+) exchanger inhibitor in mice.
    Biological & pharmaceutical bulletin, 2010, Volume: 33, Issue:4

    Topics: Amiloride; Animals; Calcium; Carotid Arteries; Cerebral Infarction; Cognition Disorders; Ischemic Preconditioning; Male; Memory; Mice; Neuroprotective Agents; Psychomotor Performance; Reperfusion Injury; Sodium; Sodium Channel Blockers; Sodium-Calcium Exchanger; Stroke

2010
Inhibition of plasminogen activation protects against ganglion cell loss in a mouse model of retinal damage.
    Molecular vision, 2003, Jun-12, Volume: 9

    Topics: alpha-2-Antiplasmin; Amiloride; Animals; Apoptosis; Blotting, Western; Cell Survival; Cytoprotection; Fibrinolysin; Immunoenzyme Techniques; In Situ Nick-End Labeling; Laminin; Ligation; Mice; Optic Nerve; Plasminogen; Plasminogen Activators; Plasminogen Inactivators; Reperfusion Injury; Retinal Diseases; Retinal Ganglion Cells; Serine Proteinase Inhibitors; Tissue Plasminogen Activator; Urokinase-Type Plasminogen Activator

2003
Na+ overload during ischemia and reperfusion in rat hearts: comparison of the Na+/H+ exchange blockers EIPA, cariporide and eniporide.
    Molecular and cellular biochemistry, 2003, Volume: 250, Issue:1-2

    Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Calcium; Guanidines; Hydrogen-Ion Concentration; Ischemia; Magnetic Resonance Spectroscopy; Male; Myocardial Contraction; Myocardium; Perfusion; Phosphates; Rats; Rats, Wistar; Reperfusion Injury; Sodium; Sodium-Hydrogen Exchangers; Sulfones; Time Factors

2003
Influence of fasting on the effects of dimethylamiloride and oxfenicine on ischaemic-reperfused rat hearts.
    Archives of physiology and biochemistry, 2006, Volume: 112, Issue:1

    Topics: Amiloride; Animals; Carnitine O-Palmitoyltransferase; Cell Survival; Enzyme Inhibitors; Fasting; Fatty Acids; Female; Glycine; Glycolysis; In Vitro Techniques; Ion Transport; Ischemic Preconditioning, Myocardial; Lactic Acid; Lipid Metabolism; Male; Muscle Cells; Myocardial Contraction; Myocardial Ischemia; Oxidation-Reduction; Rats; Rats, Wistar; Reperfusion Injury

2006
Delay of acute intracellular pH recovery after acidosis decreases endothelial cell activation.
    Journal of cellular physiology, 2007, Volume: 211, Issue:2

    Topics: Acidosis; Amiloride; Calcium; Cell Adhesion; Cells, Cultured; Chloride-Bicarbonate Antiporters; Cyclic AMP; Endothelial Cells; Endothelium, Vascular; Exocytosis; Guanidines; Histamine; Humans; Hydrogen-Ion Concentration; Interleukin-8; Intracellular Fluid; Kinetics; Linear Models; Methacrylates; P-Selectin; Platelet Adhesiveness; Reperfusion Injury; Sodium-Hydrogen Exchangers; Sulfones; Umbilical Veins; von Willebrand Factor

2007
The rise of [Na(+)] (i) during ischemia and reperfusion in the rat heart-underlying mechanisms.
    Pflugers Archiv : European journal of physiology, 2007, Volume: 454, Issue:6

    Topics: Amiloride; Anesthetics, Local; Animals; Cardiotonic Agents; Cell Separation; Female; Guanidines; In Vitro Techniques; Intracellular Space; Myocardium; Patch-Clamp Techniques; Pyrazoles; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sodium; Sodium Channel Blockers; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers; Tetrodotoxin

2007
Role of Na+/H+ exchanger in the pathogenesis of ischemic acute renal failure in mice.
    Journal of cardiovascular pharmacology, 2007, Volume: 49, Issue:3

    Topics: Acute Kidney Injury; Amiloride; Animals; Endothelin-1; Kidney; Kidney Tubular Necrosis, Acute; Kidney Tubules; Male; Mice; Protective Agents; Reperfusion Injury; Sodium-Hydrogen Exchangers

2007
Restoration of normal pH triggers ischemia-reperfusion injury in lung by Na+/H+ exchange activation.
    The American journal of physiology, 1995, Volume: 269, Issue:4 Pt 2

    Topics: Amiloride; Animals; Capillary Permeability; Hemodynamics; Hydrochloric Acid; Hydrogen-Ion Concentration; Male; Microcirculation; Pulmonary Circulation; Rats; Rats, Inbred Strains; Reperfusion Injury; Sodium-Hydrogen Exchangers

1995
Role for the Na+/H+ exchanger in reperfusion stunning in isolated perfused rat heart.
    Journal of cardiovascular pharmacology, 1993, Volume: 22, Issue:6

    Topics: Amiloride; Animals; Arrhythmias, Cardiac; Blood Pressure; Cardiac Output; Coronary Circulation; Electrolytes; Guanidines; In Vitro Techniques; Myocardial Stunning; Rats; Reperfusion Injury; Sodium-Hydrogen Exchangers; Sulfones

1993
Involvement of Na+-Ca2+ exchanger in reperfusion-induced delayed cell death of cultured rat astrocytes.
    The European journal of neuroscience, 1996, Volume: 8, Issue:5

    Topics: Amiloride; Animals; Astrocytes; Calcium; Calcium Channel Blockers; Carrier Proteins; Cell Death; Cells, Cultured; Neuroprotective Agents; Nifedipine; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sodium; Sodium-Calcium Exchanger; Time Factors

1996
Contribution of cytosolic ionic and energetic milieu change to ischemia- and reperfusion-induced injury in guinea pig heart: fluorometry and nuclear magnetic resonance studies.
    Journal of cardiovascular pharmacology, 1998, Volume: 31, Issue:1

    Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Calcium; Cytosol; Enzyme Inhibitors; Female; Fluorometry; Guinea Pigs; Heart; Hydrogen-Ion Concentration; Ion Transport; Magnetic Resonance Spectroscopy; Male; Mitochondria, Heart; Omeprazole; Ouabain; Phosphates; Reperfusion Injury

1998
5-(N-Ethyl-N-isopropyl)-amiloride, an Na(+)-H(+) exchange inhibitor, protects gerbil hippocampal neurons from ischemic injury.
    Brain research, 1999, Aug-21, Volume: 839, Issue:1

    Topics: Amiloride; Animals; Brain Ischemia; Gerbillinae; Hippocampus; Male; Neurons; Neuroprotective Agents; Reperfusion Injury; Sodium-Hydrogen Exchangers

1999
TNF-alpha stimulates alveolar liquid clearance during intestinal ischemia-reperfusion in rats.
    American journal of physiology. Lung cellular and molecular physiology, 2000, Volume: 278, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiloride; Animals; Antibodies, Monoclonal; Body Water; Capillary Permeability; Cyclic AMP; Endothelium, Vascular; Intestines; Ischemia; Lung; Male; Propranolol; Proteins; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Reference Values; Reperfusion Injury; Tumor Necrosis Factor-alpha

2000
Inhibition of Na(+)/H(+) exchange at the beginning of reperfusion is cardioprotective in isolated, beating adult cardiomyocytes.
    Journal of molecular and cellular cardiology, 2000, Volume: 32, Issue:10

    Topics: Amiloride; Animals; Cell Survival; Cells, Cultured; Hydrogen-Ion Concentration; Myocardial Reperfusion; Myocardium; Perfusion; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sodium-Hydrogen Exchangers; Spectrometry, Fluorescence; Time Factors

2000
Inhibition of Na(+)/H(+) exchange by 5-(N-ethyl-N-isopropyl)-amiloride reduces free fatty acid efflux from the ischemic reperfused rat cerebral cortex.
    Brain research, 2000, Nov-24, Volume: 884, Issue:1--2

    Topics: Acidosis; Amiloride; Animals; Brain Ischemia; Cardiovascular Physiological Phenomena; Cerebral Cortex; Electroencephalography; Fatty Acids, Nonesterified; Glucose; Lactic Acid; Male; Neuroprotective Agents; Phospholipases; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sodium-Hydrogen Exchangers

2000