amiloride has been researched along with Pain in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (9.09) | 18.2507 |
| 2000's | 11 (50.00) | 29.6817 |
| 2010's | 7 (31.82) | 24.3611 |
| 2020's | 2 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Duggan, A; García-Añoveros, J; Kumar, G; Nagata, K | 1 |
| Bilodeau, MT; Bock, MG; Cato, MJ; Chang, RK; Cook, SP; Di Marco, CN; Dipardo, RM; Hartman, GD; Jovanovska, A; Kane, SA; Kuduk, SD; Leitl, M; Spencer, RH; Urban, MO | 1 |
| Ciotu, CI; Fischer, MJM; Gleiss, A; Gold-Binder, M; Hartner, G; Heber, S; Kress, HG; Ninidze, N | 1 |
| Bandeira, PN; Campos, AR; da Silva, AW; de Menezes, JESA; Dos Reis Lima, J; Dos Santos, HS; Evaristo, FFV; Ferreira, MKA; Holanda, CLA; Magalhães, FEA; Silva, FCO; Teixeira, EH | 1 |
| Fu, X; Huang, L; Lu, Z; Wang, X; Wang, Y; Xiao, Z; Zhu, F | 1 |
| Acosta, MC; Callejo, G; Castany, M; Castellanos, A; Gallar, J; Gasull, X; Giblin, JP; Gual, A; Luna, C | 1 |
| Fischer, MJM; Namer, B; Reeh, PW; Schwarz, MG | 1 |
| García-López, BE; Granados-Soto, V; Herrejon-Abreu, EB; López-Santillán, FJ; Murbartián, J; Rocha-González, HI | 1 |
| Ambriz-Tututi, M; Araiza-Saldaña, CI; Caram-Salas, NL; Castañeda-Corral, G; Granados-Soto, V; Murbartián, J; Rocha-González, HI; Torres-López, JE | 1 |
| Cao, H; Chen, Z; Feng, EG; Jiang, H; Li, WG; Liu, H; Xu, TL; Yu, F; Yu, Y | 1 |
| Córdova, MM; Pizzolatti, MG; Ruani, AP; Santos, AR; Silva, MD; Werner, MF | 1 |
| Castañeda-Corral, G; Godínez-Chaparro, B; Granados-Soto, V; Jiménez-Andrade, JM; Rocha-González, HI | 1 |
| Cao, H; Huang, C; Li, WG; Xu, TL; Yu, Y | 1 |
| Ishida, Y; Nishigaki, M; Shibata, Y; Shimada, S; Ueda, T; Ugawa, S | 1 |
| Cadiou, H; Jones, NG; McMahon, SB; McNaughton, P; Slater, R | 1 |
| Freedman, DB; Housley, D | 1 |
| Chanda, ML; Mogil, JS | 1 |
| Bielefeldt, K; Gebhart, GF; Sugiura, T | 1 |
| Archer, DP; Roth, SH | 1 |
| Calixto, JB; Ferreira, J; Santos, AR | 1 |
| Futai, M; Sambongi, Y; Takeda, K; Ueda, I; Wada, Y; Wakabayashi, T | 1 |
| Cho, H; Lee, SY; Oh, U; Shin, CY; Shin, J | 1 |
2 trial(s) available for amiloride and Pain
| Article | Year |
|---|---|
TRPV1 antagonist BCTC inhibits pH 6.0-induced pain in human skin.
Topics: Amiloride; Animals; Ganglia, Spinal; Humans; Hydrogen-Ion Concentration; Mice; Pain; TRPV Cation Channels | 2020 |
TRPA1 and TRPV1 Antagonists Do Not Inhibit Human Acidosis-Induced Pain.
Topics: Acid Sensing Ion Channel Blockers; Acidosis; Adult; Amiloride; Analgesics; Analysis of Variance; Capsaicin; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Oximes; Pain; Pain Measurement; Pyrazines; Pyridines; TRPA1 Cation Channel; TRPV Cation Channels | 2017 |
20 other study(ies) available for amiloride and Pain
| Article | Year |
|---|---|
Nociceptor and hair cell transducer properties of TRPA1, a channel for pain and hearing.
Topics: Actins; Amiloride; Animals; Animals, Newborn; Blotting, Western; Calcium; Cell Count; Cell Line; Cloning, Molecular; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Gadolinium; Ganglia; Gentamicins; Hair Cells, Auditory; Hearing; Humans; Immunohistochemistry; In Situ Hybridization; Intermediate Filament Proteins; Isothiocyanates; Mechanoreceptors; Membrane Glycoproteins; Membrane Potentials; Mice; Nerve Tissue Proteins; Neurofilament Proteins; Neurons, Afferent; Nociceptors; Pain; Patch-Clamp Techniques; Peripherins; RNA, Messenger; Ruthenium Red; Transfection; Transient Receptor Potential Channels; TRPA1 Cation Channel; Ubiquitin Thiolesterase | 2005 |
Amiloride derived inhibitors of acid-sensing ion channel-3 (ASIC3).
Topics: Acid Sensing Ion Channels; Acidosis; Amiloride; Amines; Animals; Chemistry, Pharmaceutical; Drug Design; Electrophysiology; Inhibitory Concentration 50; Male; Models, Chemical; Nerve Tissue Proteins; Pain; Pyrazines; Rats; Rats, Sprague-Dawley; Sodium Channels | 2009 |
Antinociceptive activity of 3β-6β-16β-trihydroxylup-20 (29)-ene triterpene isolated from Combretum leprosum leaves in adult zebrafish (Danio rerio).
Topics: Acid Sensing Ion Channels; Amiloride; Analgesics; Animals; Camphor; Capsaicin; Combretum; Dose-Response Relationship, Drug; Female; Ketamine; Locomotion; Male; Methylene Blue; Naloxone; NG-Nitroarginine Methyl Ester; Nociception; Pain; Pain Measurement; Plant Extracts; Plant Leaves; Receptors, N-Methyl-D-Aspartate; Ruthenium Red; Triterpenes; TRPV Cation Channels; Zebrafish; Zebrafish Proteins | 2020 |
Increased Asics Expression via the Camkii-CREB Pathway in a Novel Mouse Model of Trigeminal Pain.
Topics: Acetic Acid; Acid Sensing Ion Channel Blockers; Acid Sensing Ion Channels; Acrylamides; Amiloride; Animals; Behavior, Animal; Bridged Bicyclo Compounds, Heterocyclic; Calcitonin Gene-Related Peptide; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Pain; Phosphorylation; Proto-Oncogene Proteins c-fos; Trigeminal Nucleus, Spinal; TRPV Cation Channels | 2018 |
Acid-sensing ion channels detect moderate acidifications to induce ocular pain.
Topics: Acid Sensing Ion Channel Blockers; Acid Sensing Ion Channels; Acids; Action Potentials; Amiloride; Animals; Blinking; Cnidarian Venoms; Cornea; Disease Models, Animal; Dry Eye Syndromes; Eye; Guanidines; Guinea Pigs; Hydrogen-Ion Concentration; Male; Nerve Fibers; Ocular Motility Disorders; Ovalbumin; Pain; Patch-Clamp Techniques; Quinazolines; Rats; Rats, Sprague-Dawley; RNA, Messenger; RNA, Small Interfering; Sensory Receptor Cells; Statistics, Nonparametric | 2015 |
Acid increases inflammatory pain in rats: effect of local peripheral ASICs inhibitors.
Topics: Acid Sensing Ion Channels; Amiloride; Analgesics; Animals; Capsaicin; Female; Formaldehyde; Hydrogen-Ion Concentration; Inflammation; Nerve Tissue Proteins; Pain; Rats; Rats, Wistar; Serotonin; Sodium Channels | 2009 |
Identification of the Na+/H+ exchanger 1 in dorsal root ganglion and spinal cord: its possible role in inflammatory nociception.
Topics: Amiloride; Animals; Behavior, Animal; Blotting, Western; Dose-Response Relationship, Drug; Female; Ganglia, Spinal; Pain; Protein Isoforms; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium Channel Blockers; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers; Spinal Cord; Time Factors | 2009 |
A nonproton ligand sensor in the acid-sensing ion channel.
Topics: Acid Sensing Ion Channels; Acids; Amiloride; Animals; Behavior, Animal; Biophysics; Calcium; Cells, Cultured; Cricetinae; Cricetulus; Disease Models, Animal; Dithionitrobenzoic Acid; Dose-Response Relationship, Drug; Electric Stimulation; Ganglia, Spinal; Glutamates; Guanidines; Hydrogen-Ion Concentration; Ion Channel Gating; Ligands; Membrane Potentials; Mice; Mice, Knockout; Mutagenesis, Site-Directed; Mutation; Nerve Tissue Proteins; Pain; Pain Measurement; Patch-Clamp Techniques; Protein Structure, Tertiary; Protons; Quinazolines; Rats; Sensory Receptor Cells; Sodium Channels; Sulfhydryl Reagents; Time Factors; Transfection | 2010 |
Further antinociceptive effects of myricitrin in chemical models of overt nociception in mice.
Topics: Acrolein; Amiloride; Analgesics, Non-Narcotic; Animals; Bradykinin; Camphor; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Flavonoids; Functional Laterality; Hyperalgesia; Male; Mice; Models, Chemical; Pain; Pain Measurement; Pain Threshold; Ruthenium Red | 2011 |
Role of the spinal Na+/H+ exchanger in formalin-induced nociception.
Topics: Amiloride; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Female; Formaldehyde; Guanidines; Neurons; Pain; Pain Measurement; Pain Threshold; Pyrazoles; Rats; Rats, Sprague-Dawley; Rats, Wistar; Sodium-Hydrogen Exchangers; Spinal Cord | 2011 |
Nonproton ligand sensing domain is required for paradoxical stimulation of acid-sensing ion channel 3 (ASIC3) channels by amiloride.
Topics: Acid Sensing Ion Channels; Amiloride; Animals; Behavior, Animal; CHO Cells; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Electrophysiology; Hydrogen-Ion Concentration; Ligands; Models, Chemical; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Pain; Protein Structure, Tertiary; Rats; Sodium Channel Blockers; Sodium Channels | 2011 |
Amiloride-blockable acid-sensing ion channels are leading acid sensors expressed in human nociceptors.
Topics: Acid Sensing Ion Channels; Adult; Amiloride; Animals; Capsaicin; Female; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Membrane Proteins; Nerve Tissue Proteins; Nociceptors; Oocytes; Pain; Psychophysics; Rats; Receptors, Drug; Recombinant Proteins; Sodium Channels; Xenopus | 2002 |
Acid-induced pain and its modulation in humans.
Topics: Acid Sensing Ion Channels; Administration, Cutaneous; Adult; Amiloride; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Diclofenac; Female; Forearm; Hot Temperature; Humans; Hydrochloric Acid; Hydrogen-Ion Concentration; Hyperalgesia; Ibuprofen; Injections, Subcutaneous; Ion Channels; Iontophoresis; Male; Membrane Proteins; Middle Aged; Nerve Tissue Proteins; Pain; Pain Measurement; Pain Threshold; Refractory Period, Electrophysiological; Single-Blind Method; Sodium Channels; TRPV Cation Channels | 2004 |
Gitelman's syndrome presenting as intolerance to statin therapy.
Topics: Adult; Amiloride; Cholesterol; Dose-Response Relationship, Drug; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypokalemia; Kidney Diseases; Magnesium; Muscular Diseases; Pain; Potassium; Pravastatin; Spironolactone; Syndrome | 2005 |
Sex differences in the effects of amiloride on formalin test nociception in mice.
Topics: Amiloride; Animals; Dose-Response Relationship, Drug; Estrogens; Female; Formaldehyde; Gonads; Hormone Replacement Therapy; Male; Mice; Pain; Pain Measurement; Pain Threshold; Sex Characteristics; Sodium Channel Blockers | 2006 |
Mouse colon sensory neurons detect extracellular acidosis via TRPV1.
Topics: Acidosis; Amiloride; Animals; Capsaicin; Cell Size; Cells, Cultured; Colon; Evoked Potentials; Extracellular Fluid; Ganglia, Spinal; Hydrogen-Ion Concentration; Kinetics; Lumbosacral Plexus; Male; Mechanotransduction, Cellular; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons, Afferent; Pain; Patch-Clamp Techniques; Sodium Channel Blockers; Thoracic Nerves; TRPV Cation Channels | 2007 |
Acetazolamide and amiloride inhibit pentobarbital-induced facilitation of nocifensive reflexes.
Topics: Acetazolamide; Amiloride; Animals; GABA Modulators; Male; NG-Nitroarginine Methyl Ester; Pain; Pentobarbital; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, GABA-A; Reflex | 1999 |
Antinociception produced by systemic, spinal and supraspinal administration of amiloride in mice.
Topics: Acetic Acid; Amiloride; Animals; Animals, Newborn; Behavior, Animal; Capsaicin; Disease Models, Animal; Diuretics; Dose-Response Relationship, Drug; Drug Administration Routes; Formaldehyde; Glutamic Acid; Hot Temperature; Hyperalgesia; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Spinal; Male; Mice; Muscle Contraction; Pain; Pain Measurement; Postural Balance | 1999 |
Caenorhabditis elegans senses protons through amphid chemosensory neurons: proton signals elicit avoidance behavior.
Topics: Amiloride; Animals; Avoidance Learning; Caenorhabditis elegans; Chemoreceptor Cells; Hydrogen-Ion Concentration; Neurons, Afferent; Pain; Receptors, Cell Surface; Receptors, Drug; Ruthenium Red; Sodium Channel Blockers; Sodium Channels | 2000 |
Mechanosensitive ion channels in cultured sensory neurons of neonatal rats.
Topics: Amiloride; Animals; Animals, Newborn; Arachidonic Acid; Calcium; Cations, Monovalent; Cell Membrane; Cell Size; Cells, Cultured; Colchicine; Cytochalasin D; Cytoskeleton; Dinoprostone; Gadolinium; Ganglia, Spinal; Ion Channels; Mechanoreceptors; Membrane Potentials; Neurons, Afferent; Nucleic Acid Synthesis Inhibitors; Pain; Patch-Clamp Techniques; Pressure; Rats; Sensory Thresholds; Touch | 2002 |