Page last updated: 2024-08-21

amiloride and Myocardial Ischemia

amiloride has been researched along with Myocardial Ischemia in 55 studies

Research

Studies (55)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	42 (76.36)	18.2507
2000's	12 (21.82)	29.6817
2010's	1 (1.82)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Andersen, AD; Bentzen, BH; Grunnet, M; Kanneworff, M; Klingberg, H; Pedersen, SF; Salling, H	1
Dong, JW; Zhou, ZN; Zhu, HF	1
Fujita, M; Gariepy, CE; Kanazawa, M; Matsumoto, N; Matsumura, Y; Takaoka, M; Yamamoto, S; Yanagisawa, M	1
Fernández, MA; García, JV; Marina Prendes, MG; Perazzo, JC; Savino, EA; Testoni, G; Varela, A	1
McCleskey, EW; Naves, LA; Wenk, HN; Yagi, J	1
Czarnowska, E; Karwatowska-Prokopczuk, E; Prokopczuk, A	1
Karmazyn, M; Li, GH; Mathur, S; Myers, ML	1
Bugge, E; Ytrehus, K	1
Cohen, SM; Maron, R; Navon, G; Werrmann, JG	1
Avkiran, M; Hearse, DJ; Ibuki, C; Yasutake, M	1
Bernard, M; Cozzone, P; Feuvray, D; Khandoudi, N	1
Cordeiro, JM; Ferrier, GR; Howlett, SE	1
Flameng, W; Hendrikx, M; Lauweryns, J; Mubagwa, K; Overloop, K; Van Hecke, P; Van Lommel, A; Vanstapel, F; Verbeken, E; Verdonck, F	1
Counillon, L; Lang, HJ; Pouysségur, J; Scholz, W	1
Karmazyn, M; Moffat, MP	1
Clark, MD; Cragoe, EJ; Kirk, KA; Kitakaze, M; Luo, CS; Madden, MC; Pike, MM; Pohost, GM	1
Albus, U; Englert, HC; Lang, HJ; Linz, W; Martorana, PA; Schölkens, BA; Scholz, W	1
Karmazyn, M	2
Bethell, HW; Grace, AA; Metcalfe, JC; Vandenberg, JI; Weissberg, PL	1
Avkiran, M; Hearse, DJ; Shimada, Y	1
Clanachan, AS; Liu, B; Lopaschuk, GD; Schulz, R	1
Bril, A; Khandoudi, N; Laville, MP	1
Fukuta, M; Iwa, T; Kobayashi, T; Uesugi, M; Wakida, Y	1
Ramasamy, R; Schaefer, S	1
Anderson, SE; Cala, PM; Liu, H	1
Kaur, H; Parikh, V; Sharma, A; Singh, M	1
Maddaford, TG; Pierce, GN	1
Cross, HR; Gabel, SA; London, RE; Murphy, E; Steenbergen, C	1
Deslauriers, R; Docherty, JC; Pierce, GN; Yang, L	1
Abete, P; Bianco, S; Cacciatore, F; Calabrese, C; Ferrara, N; Ferrara, P; Napoli, C; Rengo, F	1
de Ribaupierre, Y; Kucera, P; Meiltz, A; Raddatz, E	1
Sagar, KB; Smart, SC; Warltier, DC	1
Nakajima, N; Nakaya, H; Tamagawa, M; Yamaguchi, S	1
Banerjee, A; Cain, BS; Cleveland, JC; Harken, AH; Meldrum, DR; Rehring, TF; Shapiro, JI	1
Horike, K; Katoh, I; Kitagawa, T; Masuda, Y; Ogawa, Y; Suzuki, Y; Tamaki, T; Yoshizumi, M	1
Czarnowska, E; Karwatowska-Prokopczuk, E; Kurzydlowski, K	1
Frishman, WH; Gurell, D; Levitsky, J	1
Gerber, SH; Haass, M; Hagl, S; Heyer, C; Krüger, C; Kübler, W	1
Linakis, JG; Raymond, RM	1
Allen, DG; Park, CO; Xiao, XH	1
Funaya, H; Hori, M; Kitakaze, M; Komamura, K; Kuzuya, T; Minamino, T; Mori, H; Node, K; Takeda, H	1
Levi, R; Smith, NC	1
Ito, N; Kitano, M; Miyagishi, A; Noguchi, T; Ohashi, N; Sato, Y; Toda, H; Umekawa, K	1
Hashimoto, K	1
Ladilov, YV; Piper, HM; Schäfer, C; Schäfer, M	1
Kajiwara, H; Takasaki, A; Takeo, S; Tanonaka, K	1
Kitano, M; Matsui, K; Ohashi, N; Sasabe, M; Yamamoto, S	1
ten Hove, M; van Echteld, CJ; van Emous, JG	1
Ando, H; Hotta, Y; Ishikawa, N; Matsui, K; Nakagawa, J; Ohashi, N; Takeya, K; Wakida, Y	1
Inagaki, K; Kihara, Y; Sasayama, S; Takeuchi, Y; Yoneda, T	1
Inoue, R; Iwai, T; Kamo, N; Kasahara, S; Takeo, S; Tanonaka, K	1
Albus, U; Lang, HJ; Linz, W; Martorana, P; Schölkens, BA; Scholz, W	1
Ashida, Y; Kuroda, H; Matsuda, N; Mori, T; Okada, M	1
Imai, S; Kawada, T; Sakurai, H; Yoshida, Y	1

Reviews

3 review(s) available for amiloride and Myocardial Ischemia

Article	Year
Sodium ion/hydrogen ion exchange inhibition: a new pharmacologic approach to myocardial ischemia and reperfusion injury. Journal of clinical pharmacology, 1998, Volume: 38, Issue:10 Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Diuretics; Guanidines; Humans; Myocardial Ischemia; Myocardial Reperfusion Injury; Sodium-Hydrogen Exchangers; Sulfones	1998
The role of the myocardial sodium-hydrogen exchanger in mediating ischemic and reperfusion injury. From amiloride to cariporide. Annals of the New York Academy of Sciences, 1999, Jun-30, Volume: 874 Topics: Amiloride; Animals; Guanidines; Humans; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Sodium-Hydrogen Exchangers; Sulfones; Ventricular Remodeling	1999
[Na+/H+ exchange inhibitors]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 2000, Volume: 45, Issue:6 Suppl Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Clinical Trials as Topic; Drug Design; Guanidines; Humans; Myocardial Ischemia; Sodium-Hydrogen Exchangers; Sulfones	2000

Other Studies

52 other study(ies) available for amiloride and Myocardial Ischemia

Article	Year
The cardioprotective effect of brief acidic reperfusion after ischemia in perfused rat hearts is not mimicked by inhibition of the Na(+)/H(+) exchanger NHE1. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2011, Volume: 28, Issue:1 Topics: Acids; Amiloride; Animals; Apoptosis; Cells, Cultured; Hydrogen-Ion Concentration; Ischemic Postconditioning; Male; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; Models, Biological; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocytes, Cardiac; Necrosis; Neuroprotective Agents; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers	2011
Inhibitors of Na+/H+ and Na+/Ca2+ exchange depress intracellular calcium elevation induced by ischemia/reperfusion in rat cardiac myocytes. Sheng li xue bao : [Acta physiologica Sinica], 2003, Jun-25, Volume: 55, Issue:3 Topics: Amiloride; Animals; Calcium; Cell Hypoxia; Heart Ventricles; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocytes, Cardiac; Nickel; Rats; Rats, Sprague-Dawley; Sodium-Calcium Exchanger; Sodium-Hydrogen Exchangers	2003
Different contributions of endothelin-A and endothelin-B receptors in postischemic cardiac dysfunction and norepinephrine overflow in rat hearts. Circulation, 2005, Jan-25, Volume: 111, Issue:3 Topics: Amiloride; Animals; Animals, Genetically Modified; Atrasentan; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Gene Deletion; In Vitro Techniques; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Norepinephrine; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B; Regional Blood Flow; Ventricular Pressure	2005
Influence of fasting on the effects of dimethylamiloride and oxfenicine on ischaemic-reperfused rat hearts. Archives of physiology and biochemistry, 2006, Volume: 112, Issue:1 Topics: Amiloride; Animals; Carnitine O-Palmitoyltransferase; Cell Survival; Enzyme Inhibitors; Fasting; Fatty Acids; Female; Glycine; Glycolysis; In Vitro Techniques; Ion Transport; Ischemic Preconditioning, Myocardial; Lactic Acid; Lipid Metabolism; Male; Muscle Cells; Myocardial Contraction; Myocardial Ischemia; Oxidation-Reduction; Rats; Rats, Wistar; Reperfusion Injury	2006
Sustained currents through ASIC3 ion channels at the modest pH changes that occur during myocardial ischemia. Circulation research, 2006, Sep-01, Volume: 99, Issue:5 Topics: Acid Sensing Ion Channels; Amiloride; Animals; Cell Line; CHO Cells; Cricetinae; Cricetulus; Electric Conductivity; Heart; Hydrogen-Ion Concentration; Lactic Acid; Membrane Proteins; Myocardial Ischemia; Nerve Tissue Proteins; Neurons, Afferent; Protons; Rats; Sodium Channel Blockers; Sodium Channels	2006
Combined therapy with dimethylthiourea, diltiazem and amiloride/dimethylamiloride in the ischemic/reperfused heart. Cardiovascular research, 1995, Volume: 30, Issue:1 Topics: Amiloride; Animals; Diltiazem; Dose-Response Relationship, Drug; Drug Therapy, Combination; Endocardium; In Vitro Techniques; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Rats; Rats, Wistar; Thiourea	1995
Sodium-hydrogen exchange inhibitors improve postischemic recovery of function in the perfused rabbit heart. Cardiovascular research, 1995, Volume: 29, Issue:2 Topics: Amiloride; Animals; Heart; Male; Myocardial Ischemia; Myocardial Reperfusion; Perfusion; Rabbits; Sodium-Hydrogen Exchangers	1995
Inhibition of sodium-hydrogen exchange reduces infarct size in the isolated rat heart--a protective additive to ischaemic preconditioning. Cardiovascular research, 1995, Volume: 29, Issue:2 Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Male; Myocardial Infarction; Myocardial Ischemia; Myocardium; Perfusion; Rats; Rats, Wistar; Sodium-Hydrogen Exchangers	1995
31P NMR and triple quantum filtered 23Na NMR studies of the effects of inhibition of Na+/H+ exchange on intracellular sodium and pH in working and ischemic hearts. Magnetic resonance in medicine, 1994, Volume: 32, Issue:5 Topics: Acidosis; Amiloride; Animals; Biological Transport, Active; Cardiac Output; Coronary Circulation; Energy Metabolism; Heart Rate; Hydrogen; Hydrogen-Ion Concentration; Ion Transport; Magnetic Resonance Spectroscopy; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Phosphorus Isotopes; Rats; Rats, Sprague-Dawley; Sodium; Sodium Channels; Sodium Isotopes	1994
Na+/H+ exchange and reperfusion arrhythmias: protection by intracoronary infusion of a novel inhibitor. The American journal of physiology, 1994, Volume: 267, Issue:6 Pt 2 Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Circulation; Electrocardiography; Guanidines; Heart Rate; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Rats; Rats, Wistar; Sodium-Hydrogen Exchangers; Sulfones; Ventricular Fibrillation	1994
Mechanisms of intracellular pH regulation during postischemic reperfusion of diabetic rat hearts. Diabetes, 1995, Volume: 44, Issue:2 Topics: Amiloride; Animals; Bicarbonates; Diabetes Mellitus, Experimental; HEPES; Hydrogen-Ion Concentration; Kinetics; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Myocardial Ischemia; Myocardial Reperfusion; Rats; Rats, Wistar; Sarcolemma; Sodium-Hydrogen Exchangers; Ventricular Function, Left	1995
Simulated ischaemia and reperfusion in isolated guinea pig ventricular myocytes. Cardiovascular research, 1994, Volume: 28, Issue:12 Topics: Action Potentials; Amiloride; Animals; Calcium-Transporting ATPases; Cell Size; Cells, Cultured; Disease Models, Animal; Guinea Pigs; Heart; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium	1994
New Na(+)-H+ exchange inhibitor HOE 694 improves postischemic function and high-energy phosphate resynthesis and reduces Ca2+ overload in isolated perfused rabbit heart. Circulation, 1994, Volume: 89, Issue:6 Topics: Adenosine Triphosphate; Amiloride; Animals; Calcium; Female; Guanidines; Hemodynamics; Magnetic Resonance Spectroscopy; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Perfusion; Rabbits; Sodium-Hydrogen Exchangers; Sulfones	1994
Pharmacological characterization of stably transfected Na+/H+ antiporter isoforms using amiloride analogs and a new inhibitor exhibiting anti-ischemic properties. Molecular pharmacology, 1993, Volume: 44, Issue:5 Topics: Amiloride; Animals; Cell Line; Cricetinae; Cricetulus; DNA, Complementary; Guanidines; Myocardial Ischemia; Recombinant Proteins; Sodium-Hydrogen Exchangers; Sulfones; Transfection	1993
Protective effects of the potent Na/H exchange inhibitor methylisobutyl amiloride against post-ischemic contractile dysfunction in rat and guinea-pig hearts. Journal of molecular and cellular cardiology, 1993, Volume: 25, Issue:8 Topics: Adenine Nucleotides; Amiloride; Animals; Creatine Kinase; Glycogen; Guinea Pigs; Heart; Heart Rate; Hydrogen-Ion Concentration; In Vitro Techniques; Ion Transport; Lactates; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Phosphocreatine; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers	1993
NMR measurements of Na+ and cellular energy in ischemic rat heart: role of Na(+)-H+ exchange. The American journal of physiology, 1993, Volume: 265, Issue:6 Pt 2 Topics: Amiloride; Animals; Energy Metabolism; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Male; Myocardial Ischemia; Myocardium; Phosphates; Rats; Rats, Sprague-Dawley; Sodium; Sodium-Hydrogen Exchangers; Ventricular Function	1993
Hoe 694, a new Na+/H+ exchange inhibitor and its effects in cardiac ischaemia. British journal of pharmacology, 1993, Volume: 109, Issue:2 Topics: Adenosine Triphosphate; Amiloride; Anesthesia; Animals; Blood Platelets; Cattle; Endothelium, Vascular; Erythrocyte Membrane; Female; Glycogen; Guanidines; In Vitro Techniques; Ion Exchange; Male; Myocardial Ischemia; Phosphocreatine; Potassium; Rabbits; Rats; Rats, Sprague-Dawley; Rats, Wistar; Sodium; Sulfones	1993
Na+/H+ exchange inhibitors reverse lactate-induced depression in postischaemic ventricular recovery. British journal of pharmacology, 1993, Volume: 108, Issue:1 Topics: Amiloride; Animals; Carrier Proteins; Heart; Hydrogen; In Vitro Techniques; Lactates; Lactic Acid; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Rats; Rats, Sprague-Dawley; Sodium; Sodium-Hydrogen Exchangers	1993
Angiotensin II stimulates sodium-dependent proton extrusion in perfused ferret heart. The American journal of physiology, 1996, Volume: 270, Issue:6 Pt 1 Topics: Alkalosis; Amiloride; Angiotensin II; Animals; Bicarbonates; Female; Ferrets; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Perfusion; Pressure; Protons; Sodium; Ventricular Function, Left	1996
Impact of extracellular buffer composition on cardioprotective efficacy of Na+/H+ exchanger inhibitors. The American journal of physiology, 1996, Volume: 270, Issue:2 Pt 2 Topics: Amiloride; Animals; Bicarbonates; Buffers; Dose-Response Relationship, Drug; Extracellular Space; Guanidines; Heart; HEPES; In Vitro Techniques; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; Rats; Rats, Wistar; Sodium-Hydrogen Exchangers; Sulfones	1996
Cardiac efficiency is improved after ischemia by altering both the source and fate of protons. Circulation research, 1996, Volume: 79, Issue:5 Topics: Acetyl Coenzyme A; Adenosine Triphosphate; Amiloride; Animals; Dichloroacetic Acid; Glucose; Glycolysis; Heart; In Vitro Techniques; Male; Myocardial Ischemia; Myocardial Reperfusion; Oxidation-Reduction; Palmitic Acid; Protons; Rats; Rats, Sprague-Dawley; Time Factors; Tricarboxylic Acids	1996
Protective effect of the sodium/hydrogen exchange inhibitors during global low-flow ischemia. Journal of cardiovascular pharmacology, 1996, Volume: 28, Issue:4 Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Cardiac Output; Energy Metabolism; Guanidines; Heart; In Vitro Techniques; Male; Myocardial Ischemia; Myocardial Reperfusion; Rats; Rats, Wistar; Sodium-Hydrogen Exchangers; Sulfones	1996
Role of Na(+)-H+ exchange on reperfusion related myocardial injury and arrhythmias in an open-chest swine model. Pacing and clinical electrophysiology : PACE, 1996, Volume: 19, Issue:11 Pt 2 Topics: Action Potentials; Amiloride; Animals; Arrhythmias, Cardiac; Calcium; Cardiac Pacing, Artificial; Coloring Agents; Disease Models, Animal; Diuretics; Electrocardiography; Eosine Yellowish-(YS); Hematoxylin; Hemodynamics; Hydrogen; Infusions, Intravenous; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Necrosis; Pericardium; Phosphotungstic Acid; Sodium; Swine; Tachycardia, Ventricular; Tetrazolium Salts	1996
Short-term inhibition of the Na-H exchanger limits acidosis and reduces ischemic injury in the rat heart. Cardiovascular research, 1997, Volume: 34, Issue:2 Topics: Acidosis; Adenosine Triphosphate; Amiloride; Ammonium Chloride; Animals; Anti-Arrhythmia Agents; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Male; Myocardial Ischemia; Myocardium; Perfusion; Phosphocreatine; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers; Time Factors	1997
Ethylisopropylamiloride diminishes changes in intracellular Na, Ca and pH in ischemic newborn myocardium. Journal of molecular and cellular cardiology, 1997, Volume: 29, Issue:8 Topics: Adenosine Triphosphate; Age Factors; Amiloride; Animals; Animals, Newborn; Anti-Arrhythmia Agents; Calcium; Creatine Kinase; Heart; Hydrogen; Hydrogen-Ion Concentration; Ion Channel Gating; Ion Transport; Magnetic Resonance Spectroscopy; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Phosphates; Rabbits; Sodium; Sodium-Hydrogen Exchangers	1997
Effect of amiloride A Na+/H+ exchange inhibitor on cardioprotective effect of ischaemic preconditioning: possible involvement of resident cardiac mast cells. Pharmacological research, 1997, Volume: 36, Issue:2 Topics: Amiloride; Animals; Cell Degranulation; Female; Heart; Hydrogen-Ion Concentration; In Vitro Techniques; Mast Cells; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Peroxidases; Rats; Rats, Wistar; Sodium-Hydrogen Exchangers	1997
Myocardial dysfunction is associated with activation of Na+/H+ exchange immediately during reperfusion. The American journal of physiology, 1997, Volume: 273, Issue:5 Topics: Amiloride; Animals; Cardiotonic Agents; In Vitro Techniques; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers; Time Factors; Ventricular Dysfunction; Ventricular Function	1997
Decreased intracellular pH is not due to increased H+ extrusion in preconditioned rat hearts. The American journal of physiology, 1997, Volume: 273, Issue:5 Topics: Amiloride; Animals; Heart; Ischemic Preconditioning, Myocardial; Male; Myocardial Contraction; Myocardial Ischemia; Myocardium; Protons; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers; Time Factors	1997
Na(+)-H+ exchange inhibition at reperfusion is cardioprotective during myocardial ischemia-reperfusion; 31P NMR studies. Molecular and cellular biochemistry, 1997, Volume: 176, Issue:1-2 Topics: Amiloride; Analysis of Variance; Animals; Diuretics; Heart; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers	1997
Age-related effects of acidosis in isolated cardiac muscle. The journals of gerontology. Series A, Biological sciences and medical sciences, 1998, Volume: 53, Issue:1 Topics: Acidosis; Aging; Amiloride; Analysis of Variance; Animals; Arrhythmias, Cardiac; Diastole; Diuretics; Electrocardiography; Heart; Hydrogen-Ion Concentration; Hypercapnia; Male; Myocardial Contraction; Myocardial Ischemia; Papillary Muscles; Rats; Rats, Inbred WKY; Sodium; Sodium-Hydrogen Exchangers; Ventricular Dysfunction, Left; Ventricular Pressure	1998
Inhibition of bicarbonate transport protects embryonic heart against reoxygenation-induced dysfunction. Journal of molecular and cellular cardiology, 1998, Volume: 30, Issue:2 Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acidosis; Amiloride; Animals; Arrhythmias, Cardiac; Bicarbonates; Chick Embryo; Heart; Heart Rate; Hydrogen-Ion Concentration; Ion Transport; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Sodium-Hydrogen Exchangers	1998
Differential roles of myocardial Ca2+ channels and Na+/Ca2+ exchange in myocardial reperfusion injury in open chest dogs: relative roles during ischemia and reperfusion. Cardiovascular research, 1997, Volume: 36, Issue:3 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amiloride; Analysis of Variance; Animals; Calcium Channel Blockers; Calcium Channels; Dogs; Dose-Response Relationship, Drug; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Nifedipine; Perfusion; Random Allocation; Sodium-Calcium Exchanger; Time Factors	1997
Selective impairment of HCO3(-)-dependent pHi regulation by lysophosphatidylcholine in guinea pig ventricular myocardium. Cardiovascular research, 1998, Volume: 37, Issue:1 Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Carrier Proteins; Guinea Pigs; Hydrogen-Ion Concentration; Intracellular Fluid; Lysophosphatidylcholines; Membrane Potentials; Myocardial Ischemia; Myocardium; Papillary Muscles; Phosphatidylcholines; Sodium-Bicarbonate Symporters; Sodium-Hydrogen Exchangers	1998
Mechanisms of pH preservation during global ischemia in preconditioned rat heart: roles for PKC and NHE. The American journal of physiology, 1998, Volume: 275, Issue:3 Topics: Acidosis; Adenosine Triphosphate; Adrenergic alpha-Agonists; Amiloride; Animals; Guanidines; Hydrogen-Ion Concentration; Ischemic Preconditioning, Myocardial; Kinetics; Male; Myocardial Ischemia; Phenylephrine; Phosphates; Protein Kinase C; Rats; Rats, Sprague-Dawley; Signal Transduction; Sodium-Hydrogen Exchangers; Sulfones	1998
Effect of amiloride on ischaemia and reperfusion injury in isolated, perfused rat hearts. Scandinavian cardiovascular journal : SCJ, 1998, Volume: 32, Issue:3 Topics: Amiloride; Animals; Diuretics; Electrocardiography; Myocardial Ischemia; Myocardial Reperfusion Injury; Perfusion; Rats; Rats, Inbred WKY; Sodium-Calcium Exchanger; Sodium-Hydrogen Exchangers; Tachycardia, Ventricular; Ventricular Function, Left	1998
Ultrastructural study of calcium shift in ischemic/reperfused rat heart under treatment with dimethylthiourea, diltiazem and amiloride. Basic research in cardiology, 1998, Volume: 93, Issue:4 Topics: Amiloride; Animals; Calcium; Calcium Channel Blockers; Diltiazem; Drug Therapy, Combination; Free Radical Scavengers; Heart; Hydroxyl Radical; In Vitro Techniques; Male; Mitochondria, Heart; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Rats; Rats, Wistar; Sarcolemma; Sodium-Hydrogen Exchangers; Thiourea	1998
Influence of Bretschneider's cardioplegia on norepinephrine release from isolated perfused guinea-pig hearts. Journal of molecular and cellular cardiology, 1999, Volume: 31, Issue:1 Topics: Adrenergic Uptake Inhibitors; Amiloride; Animals; Desipramine; Dose-Response Relationship, Drug; Fever; Glucose; Guinea Pigs; Heart Arrest, Induced; Hypothermia; Ion Exchange; Mannitol; Myocardial Ischemia; Myocardium; Norepinephrine; Perfusion; Potassium Chloride; Procaine; Reperfusion; Temperature; Time Factors	1999
Effect of amiloride on age-dependent cardiac dysfunction after ischemia/reperfusion in the isolated, perfused rat heart. Shock (Augusta, Ga.), 1999, Volume: 11, Issue:3 Topics: Age Factors; Amiloride; Animals; Blood Pressure; Diuretics; Heart; Heart Rate; In Vitro Techniques; Male; Myocardial Ischemia; Myocardial Reperfusion; Rats; Rats, Sprague-Dawley; Ventricular Function, Left	1999
Changes in intracellular Na+ and pH in rat heart during ischemia: role of Na+/H+ exchanger. The American journal of physiology, 1999, Volume: 276, Issue:5 Topics: Acidosis; Amiloride; Animals; Benzofurans; Benzopyrans; Ethers, Cyclic; Female; Fluorescent Dyes; Heart Ventricles; Hydrogen-Ion Concentration; Hypoxia; Muscle Fibers, Skeletal; Myocardial Ischemia; Myocardium; Naphthols; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Rhodamines; Sodium; Sodium Lactate; Sodium-Hydrogen Exchangers; Ventricular Function, Left	1999
Nisoldipine selectively induces coronary vasodilation and improves mild myocardial ischemia in dogs: a potential role of cellular acidosis. Cardiovascular drugs and therapy, 1998, Volume: 12, Issue:6 Topics: Acidosis; Amiloride; Animals; Bicarbonates; Blood Pressure; Buffers; Coronary Circulation; Diuretics; Dogs; In Vitro Techniques; Injections, Intravenous; Myocardial Ischemia; Nisoldipine; Oxygen; Vasodilator Agents	1998
LLC-PK(1) cells stably expressing the human norepinephrine transporter: A functional model of carrier-mediated norepinephrine release in protracted myocardial ischemia. The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:2 Topics: 1-Methyl-4-phenylpyridinium; Amiloride; Animals; Biological Transport, Active; Desipramine; Drug Interactions; Gramicidin; Humans; Imidazoline Receptors; LLC-PK1 Cells; Mazindol; Models, Biological; Myocardial Ischemia; Nigericin; Norepinephrine; Receptors, Drug; Sodium; Swine; Time Factors	1999
Cardioprotection of SM-15681, an Na+/H+ exchange inhibitor in ischemic and hypoxic isolated perfused rat hearts. International journal of tissue reactions, 1999, Volume: 21, Issue:3 Topics: Amides; Amiloride; Animals; Anti-Arrhythmia Agents; Hydrogen; Indoles; Ion Transport; Myocardial Ischemia; Myocardial Reperfusion Injury; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Rats, Wistar; Sodium; Sodium-Hydrogen Exchangers	1999
Inhibition of NHE protects reoxygenated cardiomyocytes independently of anoxic Ca(2+) overload and acidosis. American journal of physiology. Heart and circulatory physiology, 2000, Volume: 279, Issue:5 Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Calcium; Carrier Proteins; Cell Hypoxia; Cells, Cultured; Cytosol; Fluorescent Dyes; Guanidines; Hydrogen-Ion Concentration; Magnesium; Male; Myocardial Contraction; Myocardial Ischemia; Myocardium; Oxygen; Rats; Rats, Wistar; Sodium; Sodium-Bicarbonate Symporters; Sodium-Hydrogen Exchangers; Sulfones	2000
Contribution of sodium channel and sodium/hydrogen exchanger to sodium accumulation in the ischemic myocardium. General pharmacology, 2000, Volume: 34, Issue:3 Topics: Amiloride; Animals; In Vitro Techniques; Ions; Male; Myocardial Contraction; Myocardial Ischemia; Myocardium; Rats; Rats, Wistar; Sodium; Sodium Channel Blockers; Sodium Channels; Sodium-Hydrogen Exchangers; Tetrodotoxin; Ventricular Function, Left	2000
Effect of SMP-300, a new Na+/H+ exchange inhibitor, on myocardial ischemia and experimental angina models in rats. Japanese journal of pharmacology, 2000, Volume: 84, Issue:2 Topics: Amiloride; Angina Pectoris; Animals; Azocines; Blood Pressure; Disease Models, Animal; Electrocardiography; Heart; Heart Rate; Isoproterenol; Male; Myocardial Ischemia; Myocardium; Neuroprotective Agents; Pyrroles; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers; Vasopressins	2000
Na+-overload during ischemia and reperfusion in rat hearts: comparison of the Na+/H+-exchange blockers EIPA, HOE642 and EMD96785. Magma (New York, N.Y.), 2000, Volume: 11, Issue:1-2 Topics: Amiloride; Animals; Guanidines; In Vitro Techniques; Magnetic Resonance Spectroscopy; Myocardial Ischemia; Myocardial Reperfusion Injury; Rats; Sodium; Sodium-Hydrogen Exchangers; Sulfones	2000
Protective effect of SM-20550, a selective Na+ - H+ exchange inhibitor, on ischemia-reperfusion-injured hearts. Journal of cardiovascular pharmacology, 2001, Volume: 37, Issue:2 Topics: Adenosine Triphosphate; Amidines; Amiloride; Animals; Calcium; Female; Guinea Pigs; Hydrogen-Ion Concentration; Indoles; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Protective Agents; Sodium; Sodium-Hydrogen Exchangers; Ventricular Function, Left	2001
Endothelin-1 has a unique oxygen-saving effect by increasing contractile efficiency in the isolated rat heart. Circulation, 2001, Mar-20, Volume: 103, Issue:11 Topics: Amiloride; Animals; Antihypertensive Agents; Caffeic Acids; Cardiotonic Agents; Drug Interactions; Endothelin-1; Heart; In Vitro Techniques; Male; Myocardial Contraction; Myocardial Ischemia; Oleanolic Acid; Oligopeptides; Oxygen; Perfusion; Piperidines; Rats; Rats, Sprague-Dawley	2001
Mitochondrial damage during ischemia determines post-ischemic contractile dysfunction in perfused rat heart. Journal of molecular and cellular cardiology, 2002, Volume: 34, Issue:7 Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Cytochrome c Group; In Vitro Techniques; Male; Membrane Potentials; Mitochondria; Myocardial Ischemia; Myocardial Reperfusion; Oxidative Phosphorylation; Rats; Rats, Wistar; Sodium; Tetrodotoxin	2002
Effects of Na+/H+ exchange inhibitors in cardiac ischemia. Journal of molecular and cellular cardiology, 1992, Volume: 24, Issue:7 Topics: Amiloride; Animals; Carrier Proteins; Erythrocytes; Hydrogen; In Vitro Techniques; Ion Transport; Male; Myocardial Ischemia; Rabbits; Rats; Rats, Sprague-Dawley; Sodium; Sodium-Hydrogen Exchangers	1992
Possible involvement of Na(+)-H+ exchange in the early phase of reperfusion in myocardial stunning. The Journal of surgical research, 1992, Volume: 53, Issue:5 Topics: Amiloride; Animals; Calcium; Cardiac Output; Carrier Proteins; Coronary Circulation; Creatine Kinase; Heart; Heart Rate; Hydrogen; Male; Myocardial Ischemia; Myocardial Reperfusion; Rats; Rats, Wistar; Sodium; Sodium-Hydrogen Exchangers	1992
Myocardial Na+ during ischemia and accumulation of Ca2+ after reperfusion: a study with monensin and dichlorobenzamil. Japanese journal of pharmacology, 1992, Volume: 59, Issue:2 Topics: Adenine Nucleotides; Amiloride; Animals; Calcium; In Vitro Techniques; Ion Transport; Male; Monensin; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Perfusion; Potassium; Rats; Sodium	1992