Compounds > amiloride
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amiloride and Metabolic Acidosis

amiloride has been researched along with Metabolic Acidosis in 103 studies

Research

Studies (103)

TimeframeStudies, this research(%)All Research%
pre-199022 (21.36)18.7374
1990's50 (48.54)18.2507
2000's18 (17.48)29.6817
2010's12 (11.65)24.3611
2020's1 (0.97)2.80

Authors

AuthorsStudies
Bilodeau, MT; Bock, MG; Cato, MJ; Chang, RK; Cook, SP; Di Marco, CN; Dipardo, RM; Hartman, GD; Jovanovska, A; Kane, SA; Kuduk, SD; Leitl, M; Spencer, RH; Urban, MO1
Choi, BY; Hong, DK; Jeong, JH; Kang, BS; Kang, DH; Kho, AR; Lee, SH; Park, MK; Suh, SW1
Grohovaz, F; Mazzocchi, N; Menegon, A; Taverna, S1
Du, W; Fang, M; Gong, F; Kong, X; Tan, Z; Tang, X; Tong, J; Yan, Y; Zheng, F1
Chen, CJ; Fichna, J; Gu, Y; Hao, CM; Lai, LY; Li, K; Li, M; Li, YY; Lin, SY; Liu, SJ; Peng, A; Su, W; Zhang, MM1
Qing, C; Zeng, X; Zhang, H; Zhang, Y1
Amelkina, GA; Genrikhs, EE; Isaev, NK; Ivashkin, EG; Khaspekov, LG; Novikova, SV; Stelmashook, EV1
Fischer, MJM; Namer, B; Reeh, PW; Schwarz, MG1
Frew, R; Nelson, PP; Sawyer, TW; Tenn, C; Vair, C; Wang, Y; Weiss, MT; Yin, J1
Hagiwara, N; Ibayashi, S; Iida, M; Kamouchi, M; Kitazono, T; Kuroda, J; Nakamura, K; Ooboshi, H; Shono, Y1
Baum, M; Bobulescu, IA; Dwarakanath, V; Gattineni, J; Twombley, K1
Bloch-Faure, M; Eladari, D; Houillier, P; Jacques, T; Keck, M; Lourdel, S; Paulais, M; Picard, N; Ramakrishnan, SK; Sohet, F; Teulon, J; Tucker, SJ1
Bo, Y; Ming, G; Yuan, LP; Zhou, QL1
Cao, Y; Geng, W; Jin, W; Li, L; Liu, Z; Shen, L; Song, N; Yu, J; Zhang, G; Zhu, D1
Fedorovich, SV; Lemeshchenko, VV; Lyskova, TI; Pekun, TG; Waseem, TV1
Chu, XP; Li, GH; MacDonald, JF; Simon, RP; Wei, WL; Xiong, ZG; Zhu, XM1
Amemiya, M; Asano, Y; Funayama, I; Imamura, S; Kusano, E; Mori, H; Tabei, K; Toyoda, A1
Bock, J; Gerhardt, E; Lang, F; Müller, MM; Schneider, D; Schulz, JB; Wolburg, H1
Browning, JA; Wilkins, RJ1
Nagami, GT1
Adam-Vizi, V; Sipos, H; Törocsik, B; Tretter, L1
Bose, R; Parkinson, FE; Zamzow, CR1
Goerge, T; Huck, V; Niemeyer, A; Oberleithner, H; Ossig, R; Rogge, P; Schnaeker, EM; Schneider, MF; Schneider, SW1
Bielefeldt, K; Gebhart, GF; Sugiura, T1
Advenier, C; Devillier, P; Fagon, JY; Faisy, C; Frossard, N; Naline, E; Planquette, B; Risse, PA1
Alpern, RJ; Ives, HE; Rector, FC; Tsai, CJ; Warnock, DG; Yee, VJ1
Cujdik, T; Kinsella, J; Sacktor, B1
Kornandakieti, C; Tannen, RL1
Grekin, R; Kornandakieti, C; Tannen, RL1
Fantoli, U1
Arruda, JA; Dytko, G; Kurtzman, NA; Mola, R; Subbarayudu, K1
Lye, MD; Wan, HH1
Cragoe, EJ; Hotokebuchi, N; Lai, ZF; Nishi, K1
Rozanski, GJ; Witt, RC1
Bastani, B; Bookstein, C; Chang, EB; Rao, MC; Singh, G; Soleimani, M1
Cascio, WE; Gilliam, DE; Kaplan, SH; Lemasters, JJ; Shen, J; Yang, H1
Moffat, MP; Ward, CA1
Cohen, SM; Maron, R; Navon, G; Werrmann, JG1
Boisvert, DM; Buckman, S; Harrison, V; Iacovitti, M; Levine, DZ; Nadler, SP; Vandorpe, D1
Ayajiki, K; Enokibori, M; Okamura, T; Toda, N1
Crevat, A; Gallice, P; Kovacic, H; Sarrazin, M1
Dafnis, E; Eiam-Ong, S; Kurtzman, NA; Sabatini, S; Spohn, M1
Borzak, S; Kelly, RA; Kraemer, B; Marsh, JD; Navas, JP; Nishida, M; Smith, TW1
Canioni, P; Cozzone, PJ; Durand, T; Gallis, JL; Masson, S1
Radda, GK; Schussheim, AE1
Albuquerque, ML; Haffner, J; Hsu, P; Leffler, CW1
Abe, T; Akita, T; Hotta, Y; Kodama, I; Koike, A; Murase, M; Takeya, K; Toyama, J1
Jo, D; Thomas, AG; Vornov, JJ1
Good, DW; Watts, BA1
Hamm, PH; Jackson, DC; Lawler, RG; Meyers, RS; Shi, H1
Ramasamy, R; Schaefer, S2
Davies, SE; Gotoh, M; Obrenovitch, TP1
Ayajiki, K; Okamura, T; Toda, N1
Abete, P; Bianco, S; Cacciatore, F; Calabrese, C; Ferrara, N; Ferrara, P; Napoli, C; Rengo, F1
de Ribaupierre, Y; Kucera, P; Meiltz, A; Raddatz, E1
Banerjee, A; Cain, BS; Cleveland, JC; Harken, AH; Meldrum, DR; Rehring, TF; Shapiro, JI1
Canioni, P; Durand, T; Gallis, JL; Vidal, G1
Baltz, JM; Bavister, BD; Lane, M1
Bonanno, JA; Harvitt, DM1
Chiu, HM; Lin, HH; Tang, MJ1
Allen, DG; Park, CO; Xiao, XH1
Cobo, JM; Díaz-Gil, JJ; García-Cañero, R; Pérez de Diego, J; Trilla, C1
Funaya, H; Hori, M; Kitakaze, M; Komamura, K; Kuzuya, T; Minamino, T; Mori, H; Node, K; Takeda, H1
Baethmann, A; Haberstok, J; Kölbl, I; Peters, J; Plesnila, N; Staub, F1
Varming, T1
Aschenbach, JR; Gäbel, G; Müller, F1
Goldstein, JI; Leiter, JC; Mok, JM; Simon, CM1
O'Regan, MH; Phillis, JW; Ren, J1
Choi, HS; Eisner, DA; Orchard, CH; Trafford, AW1
Baron, O; Rebeyka, IM; Saiki, Y1
Buhay, S; Erlichman, JS; Leiter, JC; Nottingham, S; Wages, P1
Morgan, JP; Wang, J1
Clément-Chomienne, O; Pucéat, M; Terzic, A; Vassort, G1
Capogrossi, MC; Carbonin, P; Gambassi, G1
Boyett, MR; Frampton, JE; Harrison, SM; McCall, E; Orchard, CH1
Alpern, RJ; Benjamin, IJ; Greenberg, ML; Horie, S; Williams, RS1
Sahai, A; Sandler, RS; Shayman, JA; Tannen, RL; Xu, G1
Hall, MC; Koch, MO; McDougal, WS1
Alpern, RJ; Cano, A; Horie, S; Miller, RT; Moe, OW; Preisig, PA1
Cragoe, EJ; Momma, K; Nakanishi, T; Seguchi, M; Takao, A; Tsuchiya, T1
Hemsworth, PD; Rasmussen, HH; Whalley, DW1
Ghysel-Burton, J; Godfraind, T1
Carter, KJ; Goddard, PJ; Heissenberg, MC; Silen, W; Yanaka, A1
Johanson, CE; Murphy, VA2
Baethmann, A; Jansen, M; Kempski, O; Staub, F1
Bose, R; Guia, A1
Blot-Chabaud, M; Corbic, M; Dumont, M; Erlinger, S1
Gores, GJ; Herman, B; Lemasters, JJ; Nieminen, AL; Wray, BE1
Cragoe, EJ; Hamm, LL; Herndon, J; Merli, C; Simon, EE1
Altenberg, GA; Amorena, CE; Aristimuño, PC; Taquini, AC1
Aperia, A; Fukuda, Y1
Frelin, C; Lazdunski, M; Vigne, P1
Kinsella, JL; Sacktor, B1
Kurtzman, NA; Mujais, SK; Nascimento, L; Rademacher, DR; Wilson, A1
Bateman, NT; Baudouin, SV1
Baethmann, A; Jansen, M; Kempski, O; Schödel, F; Staub, F1
Frazier, LW1
Fanestil, DD; Ludens, JH; Ziegler, TW1
Bianchi Porro, G; Petrillo, M1
Ellison, AC; Maren, TH1
Hohenegger, M; Marktl, W; Selzer, H1

Reviews

2 review(s) available for amiloride and Metabolic Acidosis

ArticleYear
The sodium/hydrogen exchange system in cardiac cells: its biochemical and pharmacological properties and its role in regulating internal concentrations of sodium and internal pH.
    Journal of molecular and cellular cardiology, 1985, Volume: 17, Issue:11

    Topics: Acidosis; Amiloride; Animals; Antiporters; Biological Transport, Active; Calcium; Carrier Proteins; Cells, Cultured; Chickens; Coronary Disease; Digitalis; Hydrogen; Hydrogen-Ion Concentration; Kinetics; Myocardium; Plants, Medicinal; Plants, Toxic; Sodium

1985
Hormonal effects on sodium cotransport systems.
    Annals of the New York Academy of Sciences, 1985, Volume: 456

    Topics: Acidosis; Adrenalectomy; Amiloride; Animals; Biological Transport, Active; Calcitriol; Carrier Proteins; Cells, Cultured; Chickens; Dexamethasone; Dopamine; Electrochemistry; Glucocorticoids; Growth Hormone; Hyperthyroidism; Kidney Tubules, Proximal; Kinetics; Microvilli; Parathyroid Hormone; Phosphates; Protons; Rats; Sodium; Sodium-Hydrogen Exchangers; Thyroxine

1985

Trials

1 trial(s) available for amiloride and Metabolic Acidosis

ArticleYear
TRPA1 and TRPV1 Antagonists Do Not Inhibit Human Acidosis-Induced Pain.
    The journal of pain, 2017, Volume: 18, Issue:5

    Topics: Acid Sensing Ion Channel Blockers; Acidosis; Adult; Amiloride; Analgesics; Analysis of Variance; Capsaicin; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Oximes; Pain; Pain Measurement; Pyrazines; Pyridines; TRPA1 Cation Channel; TRPV Cation Channels

2017

Other Studies

100 other study(ies) available for amiloride and Metabolic Acidosis

ArticleYear
Amiloride derived inhibitors of acid-sensing ion channel-3 (ASIC3).
    Bioorganic & medicinal chemistry letters, 2009, May-01, Volume: 19, Issue:9

    Topics: Acid Sensing Ion Channels; Acidosis; Amiloride; Amines; Animals; Chemistry, Pharmaceutical; Drug Design; Electrophysiology; Inhibitory Concentration 50; Male; Models, Chemical; Nerve Tissue Proteins; Pain; Pyrazines; Rats; Rats, Sprague-Dawley; Sodium Channels

2009
An Inhibitor of the Sodium-Hydrogen Exchanger-1 (NHE-1), Amiloride, Reduced Zinc Accumulation and Hippocampal Neuronal Death after Ischemia.
    International journal of molecular sciences, 2020, Jun-14, Volume: 21, Issue:12

    Topics: Acidosis; Amiloride; Animals; Brain Ischemia; Cell Death; Disease Models, Animal; Epithelial Sodium Channel Blockers; Hippocampus; Injections, Intraperitoneal; Male; Mice; Neurons; Oxidative Stress; Zinc

2020
Membrane potential changes occurring upon acidification influence the binding of small-molecule inhibitors to ASIC1a.
    Neuropharmacology, 2019, Volume: 148

    Topics: Acid Sensing Ion Channel Blockers; Acid Sensing Ion Channels; Acidosis; Amiloride; Animals; Cells, Cultured; Cricetinae; Diminazene; Hippocampus; Membrane Potentials; Neurons; Spider Venoms

2019
Extracellular acidosis modulates the endocytosis and maturation of macrophages.
    Cellular immunology, 2013, Volume: 281, Issue:1

    Topics: Acid Sensing Ion Channel Blockers; Acid Sensing Ion Channels; Acidosis; Amiloride; Animals; Bone Marrow Cells; Cells, Cultured; Endocytosis; Female; Interleukin-10; Macrophages; Mice; Mice, Inbred C57BL

2013
Acid loading stimulates rat glomerular mesangial cells proliferation through Na(+)-H (+) exchanger isoform 1 (NHE1)-dependent pathway.
    Naunyn-Schmiedeberg's archives of pharmacology, 2013, Volume: 386, Issue:6

    Topics: Acidosis; Amiloride; Animals; Blotting, Western; Cell Cycle; Cell Proliferation; Disease Progression; Flow Cytometry; Fluoresceins; Hydrogen-Ion Concentration; Mesangial Cells; Rats; Renal Insufficiency, Chronic; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers; Staining and Labeling; Tetrazolium Salts; Thiazoles

2013
L-type Ca2+ channel blocker attenuates impairment induced by acidosis in hippocampal neurons.
    Die Pharmazie, 2013, Volume: 68, Issue:11

    Topics: Acidosis; Amiloride; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Signaling; Cell Death; Cell Size; Diuretics; Hippocampus; Membrane Potential, Mitochondrial; Neurons; Nifedipine; Primary Cell Culture; Rats

2013
Acidosis and 5-(N-ethyl-N-isopropyl)amiloride (EIPA) Attenuate Zinc/Kainate Toxicity in Cultured Cerebellar Granule Neurons.
    Biochemistry. Biokhimiia, 2015, Volume: 80, Issue:8

    Topics: Acidosis; Amiloride; Animals; Calcium; Cations, Divalent; Cell Death; Cells, Cultured; Cerebellum; Cytoplasmic Granules; Drug Interactions; Kainic Acid; Neurons; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Sodium-Hydrogen Exchangers; Zinc

2015
Role of the sodium hydrogen exchanger in maitotoxin-induced cell death in cultured rat cortical neurons.
    Toxicon : official journal of the International Society on Toxinology, 2009, Volume: 54, Issue:2

    Topics: Acidosis; Amiloride; Animals; Antimetabolites, Antineoplastic; Calcium; Cell Death; Cell Survival; Cells, Cultured; Cerebral Cortex; Female; Fluorometry; Marine Toxins; Methotrexate; Necrosis; Neurons; Neuroprotective Agents; Oxocins; Pregnancy; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Sodium-Hydrogen Exchangers

2009
Change in intracellular pH causes the toxic Ca2+ entry via NCX1 in neuron- and glia-derived cells.
    Cellular and molecular neurobiology, 2010, Volume: 30, Issue:3

    Topics: Acidosis; Amiloride; Calcium; Calcium Signaling; Cell Death; Cell Line, Tumor; Cell Survival; Cytosol; Extracellular Fluid; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; Hypoxia-Ischemia, Brain; Nerve Degeneration; Neuroglia; Neurons; Propionates; Sodium; Sodium-Calcium Exchanger

2010
Effect of metabolic acidosis on neonatal proximal tubule acidification.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2010, Volume: 299, Issue:5

    Topics: Acidosis; Adaptation, Physiological; Amiloride; Animals; Animals, Newborn; Bicarbonates; Disease Models, Animal; Gene Expression Regulation; Hydrogen-Ion Concentration; Kidney Tubules, Proximal; Mice; Mice, Inbred C57BL; Microvilli; Rats; RNA, Messenger; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Time Factors

2010
Renal phenotype in mice lacking the Kir5.1 (Kcnj16) K+ channel subunit contrasts with that observed in SeSAME/EAST syndrome.
    Proceedings of the National Academy of Sciences of the United States of America, 2011, Jun-21, Volume: 108, Issue:25

    Topics: Acidosis; Amiloride; Animals; Diuretics; Furosemide; Humans; Hydrochlorothiazide; Hypokalemia; Kidney Tubules; Kir5.1 Channel; Mice; Mice, Knockout; Patch-Clamp Techniques; Phenotype; Potassium Channels, Inwardly Rectifying; Sodium Channel Blockers; Sodium Potassium Chloride Symporter Inhibitors; Syndrome

2011
Expression of acid-sensing ion channels of gastric mucosa from patients with Henoch-Schönlein purpura.
    Journal of pediatric gastroenterology and nutrition, 2012, Volume: 54, Issue:4

    Topics: Acid Sensing Ion Channels; Acidosis; Adolescent; Amiloride; Biopsy; Case-Control Studies; Child; Female; Gastric Mucosa; Gastrointestinal Diseases; Gastrointestinal Tract; Gene Expression Regulation; Humans; IgA Vasculitis; Immunohistochemistry; Male; Nerve Tissue Proteins; Sodium Channels

2012
Acid sensing ion channel 1 in lateral hypothalamus contributes to breathing control.
    PloS one, 2012, Volume: 7, Issue:7

    Topics: Acid Sensing Ion Channel Blockers; Acid Sensing Ion Channels; Acidosis; Amiloride; Animals; Arterial Pressure; Body Weight; Gene Expression; Heart Rate; Hydrogen-Ion Concentration; Hypothalamus; Intracellular Signaling Peptides and Proteins; Male; Neurons; Neuropeptides; Orexins; Phrenic Nerve; Rats; Rats, Sprague-Dawley; Respiration; Respiratory Center; Respiratory Rate

2012
Influence of intra- and extracellular acidification on free radical formation and mitochondria membrane potential in rat brain synaptosomes.
    Journal of molecular neuroscience : MN, 2013, Volume: 49, Issue:1

    Topics: Acidosis; Amiloride; Animals; Brain; Extracellular Space; Fluorescent Dyes; Hydrogen-Ion Concentration; Intracellular Space; Male; Membrane Potential, Mitochondrial; Mitochondria; Oxidative Stress; Rats; Rats, Wistar; Superoxides; Synaptosomes; Uncoupling Agents; Voltage-Sensitive Dye Imaging

2013
Acidosis decreases low Ca(2+)-induced neuronal excitation by inhibiting the activity of calcium-sensing cation channels in cultured mouse hippocampal neurons.
    The Journal of physiology, 2003, Jul-15, Volume: 550, Issue:Pt 2

    Topics: Acidosis; Amiloride; Animals; Calcium; Cells, Cultured; Diuretics; Electric Stimulation; Electrophysiology; Hippocampus; Hydrogen-Ion Concentration; Membrane Potentials; Mice; Neurons; Patch-Clamp Techniques; Receptors, Calcium-Sensing

2003
Stimulation of NHE3 in OKP cells by an autocrine mechanism.
    Nephron. Experimental nephrology, 2004, Volume: 96, Issue:1

    Topics: Acidosis; Amiloride; Angiotensin II; Animals; Autocrine Communication; Benzoquinones; Cell Line; Culture Media, Conditioned; Dose-Response Relationship, Drug; Endothelin B Receptor Antagonists; Endothelin-1; Hydrogen-Ion Concentration; Kidney; Lactams, Macrocyclic; Oligopeptides; Opossums; Piperidines; Potassium; Protein-Tyrosine Kinases; Quinones; Receptor, Endothelin B; Rifabutin; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Time Factors

2004
Intracellular acidification by inhibition of the Na+/H+-exchanger leads to caspase-independent death of cerebellar granule neurons resembling paraptosis.
    Cell death and differentiation, 2004, Volume: 11, Issue:7

    Topics: Acidosis; Adenoviridae; Amiloride; Animals; Apoptosis; Caspases; Cell Survival; Cells, Cultured; Cerebellum; Cycloheximide; Dose-Response Relationship, Drug; Guanidines; Hydrogen-Ion Concentration; Neurons; Potassium; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers; Sulfones

2004
Mechanisms contributing to intracellular pH homeostasis in an immortalised human chondrocyte cell line.
    Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2004, Volume: 137, Issue:2

    Topics: Acidosis; Amiloride; Bicarbonates; Buffers; Cell Line; Chondrocytes; Guanidines; HEPES; Homeostasis; Humans; Hydrogen-Ion Concentration; Sodium; Sulfones

2004
Ammonia production and secretion by S3 proximal tubule segments from acidotic mice: role of ANG II.
    American journal of physiology. Renal physiology, 2004, Volume: 287, Issue:4

    Topics: Acid-Base Equilibrium; Acidosis; Amiloride; Ammonia; Ammonium Chloride; Angiotensin II; Animals; Buffers; Carbon Dioxide; Diuretics; Kidney Tubules, Proximal; Male; Mice; Sodium; Vasoconstrictor Agents

2004
Impaired regulation of pH homeostasis by oxidative stress in rat brain capillary endothelial cells.
    Cellular and molecular neurobiology, 2005, Volume: 25, Issue:1

    Topics: Acidosis; Amiloride; Ammonium Chloride; Animals; Blood-Brain Barrier; Buffers; Cells, Cultured; Culture Media; Endothelial Cells; HEPES; Homeostasis; Hydrogen Peroxide; Hydrogen-Ion Concentration; Neuroprotective Agents; Oxidants; Oxidative Stress; Rats; Rats, Inbred Lew; Sodium; Sodium-Hydrogen Exchangers

2005
The effect of acidosis on adenosine release from cultured rat forebrain neurons.
    Brain research, 2006, Apr-12, Volume: 1082, Issue:1

    Topics: Acetates; Acidosis; Adenosine; Amiloride; Analysis of Variance; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Excitatory Amino Acid Agonists; Fluoresceins; Hydrogen-Ion Concentration; Methylamines; Models, Biological; N-Methylaspartate; Neurons; Neuroprotective Agents; Prosencephalon; Purines; Rats; Time Factors; Tritium

2006
Delay of acute intracellular pH recovery after acidosis decreases endothelial cell activation.
    Journal of cellular physiology, 2007, Volume: 211, Issue:2

    Topics: Acidosis; Amiloride; Calcium; Cell Adhesion; Cells, Cultured; Chloride-Bicarbonate Antiporters; Cyclic AMP; Endothelial Cells; Endothelium, Vascular; Exocytosis; Guanidines; Histamine; Humans; Hydrogen-Ion Concentration; Interleukin-8; Intracellular Fluid; Kinetics; Linear Models; Methacrylates; P-Selectin; Platelet Adhesiveness; Reperfusion Injury; Sodium-Hydrogen Exchangers; Sulfones; Umbilical Veins; von Willebrand Factor

2007
Mouse colon sensory neurons detect extracellular acidosis via TRPV1.
    American journal of physiology. Cell physiology, 2007, Volume: 292, Issue:5

    Topics: Acidosis; Amiloride; Animals; Capsaicin; Cell Size; Cells, Cultured; Colon; Evoked Potentials; Extracellular Fluid; Ganglia, Spinal; Hydrogen-Ion Concentration; Kinetics; Lumbosacral Plexus; Male; Mechanotransduction, Cellular; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons, Afferent; Pain; Patch-Clamp Techniques; Sodium Channel Blockers; Thoracic Nerves; TRPV Cation Channels

2007
Acid-induced modulation of airway basal tone and contractility: role of acid-sensing ion channels (ASICs) and TRPV1 receptor.
    Life sciences, 2007, Sep-08, Volume: 81, Issue:13

    Topics: Acid Sensing Ion Channels; Acidosis; Amiloride; Animals; Capsaicin; Enzyme Inhibitors; Guinea Pigs; Hydrogen-Ion Concentration; Male; Membrane Proteins; Muscle Contraction; Muscle Relaxation; Muscle Tonus; Nerve Tissue Proteins; Poisons; Receptors, Tachykinin; Sensory Receptor Cells; Sodium Channel Blockers; Sodium Channels; Tetrodotoxin; Trachea; TRPV Cation Channels

2007
Increased Vmax for Na+/H+ antiporter activity in proximal tubule brush border vesicles from rabbits with metabolic acidosis.
    The American journal of physiology, 1984, Volume: 247, Issue:2 Pt 2

    Topics: Acidosis; Acridine Orange; Amiloride; Animals; Bicarbonates; Carbon Dioxide; Carrier Proteins; Female; Kidney Tubules, Proximal; Kinetics; Microvilli; Rabbits; Sodium-Hydrogen Exchangers

1984
Na+-H+ exchange activity in renal brush border membrane vesicles in response to metabolic acidosis: The role of glucocorticoids.
    Proceedings of the National Academy of Sciences of the United States of America, 1984, Volume: 81, Issue:2

    Topics: Acidosis; Adrenalectomy; Amiloride; Ammonia; Animals; Carrier Proteins; Glucocorticoids; Hydrogen-Ion Concentration; Kidney Cortex; Kinetics; Male; Microvilli; Phosphates; Rats; Sodium; Sodium-Hydrogen Exchangers

1984
Hydrogen ion secretion by the distal nephron in the rat: effect of potassium.
    The Journal of laboratory and clinical medicine, 1984, Volume: 104, Issue:3

    Topics: Acidosis; Alkalosis; Amiloride; Animals; Creatinine; Diet; Glomerular Filtration Rate; Homeostasis; Hydrogen; Hydrogen-Ion Concentration; Kidney; Male; Potassium; Potassium Deficiency; Rats; Rats, Inbred Strains

1984
Hydrogen ion secretion by the rat distal nephron: adaptation to chronic alkali and acid ingestion.
    The American journal of physiology, 1983, Volume: 245, Issue:3

    Topics: Acclimatization; Acidosis; Acute Disease; Alkalosis; Amiloride; Ammonium Chloride; Animals; Chronic Disease; Hydrogen-Ion Concentration; Kidney; Kidney Tubules; Kidney Tubules, Distal; Kinetics; Male; Nephrons; Rats; Rats, Inbred Strains

1983
["Short-circuit" renal tubular acidosis. A new syndrome?].
    Recenti progressi in medicina, 1981, Volume: 71, Issue:1

    Topics: Acidosis; Acidosis, Renal Tubular; Amiloride; Animals; Chlorides; Digoxin; Dogs; Electrolytes; Humans; Hypokalemia; Lithium; Syndrome; Tromethamine

1981
Voltage-dependent distal acidification defect induced by amiloride.
    The Journal of laboratory and clinical medicine, 1980, Volume: 95, Issue:3

    Topics: Acidosis; Amiloride; Ammonium Chloride; Animals; Electrochemistry; Potassium; Pyrazines; Rats; Sodium; Turtles; Urinary Bladder

1980
Moduretic-induced metabolic acidosis and hyperkalaemia.
    Postgraduate medical journal, 1980, Volume: 56, Issue:655

    Topics: Acidosis; Aged; Amiloride; Drug Combinations; Humans; Hydrochlorothiazide; Hyperkalemia; Male; Pyrazines

1980
Effects of 5-(N,N-hexamethylene)amiloride on action potentials, intracellular Na, and pH of guinea pig ventricular muscle in vitro.
    Journal of cardiovascular pharmacology, 1994, Volume: 23, Issue:2

    Topics: Acidosis; Action Potentials; Amiloride; Ammonium Chloride; Animals; Female; Guinea Pigs; Heart; Heart Ventricles; Hydrogen-Ion Concentration; In Vitro Techniques; Ion-Selective Electrodes; Kinetics; Male; Microelectrodes; Myocardium; Papillary Muscles; Sodium

1994
Interleukin-1 enhances beta-responsiveness of cardiac L-type calcium current suppressed by acidosis.
    The American journal of physiology, 1994, Volume: 267, Issue:4 Pt 2

    Topics: Acidosis; Alkaloids; Amiloride; Animals; Calcium Channels; Cells, Cultured; Guinea Pigs; Heart; Heart Ventricles; Humans; Interleukin-1; Isoproterenol; Kinetics; Male; Membrane Potentials; Naphthalenes; Polycyclic Compounds; Protein Kinase C; Recombinant Proteins; Sodium; Sodium-Hydrogen Exchangers; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors

1994
Differential regulation of Na+/H+ exchange and H(+)-ATPase by pH and HCO3- in kidney proximal tubules.
    The Journal of membrane biology, 1995, Volume: 144, Issue:3

    Topics: Acidosis; Alkalosis; Amiloride; Animals; Bicarbonates; Blotting, Western; Hydrogen-Ion Concentration; In Vitro Techniques; Kidney Tubules, Proximal; Male; Microvilli; Proton-Translocating ATPases; Rabbits; Sodium; Sodium-Hydrogen Exchangers

1995
Hypercapnic acidosis and dimethyl amiloride reduce reperfusion induced cell death in ischaemic ventricular myocardium.
    Cardiovascular research, 1995, Volume: 29, Issue:2

    Topics: Acidosis; Amiloride; Animals; Cell Death; Hydrogen-Ion Concentration; Hypercapnia; In Vitro Techniques; Myocardial Reperfusion Injury; Myocardium; Papillary Muscles; Rabbits; Sodium-Hydrogen Exchangers

1995
Modulation of sodium-hydrogen exchange activity in cardiac myocytes during acidosis and realkalinisation: effects on calcium, pHi, and cell shortening.
    Cardiovascular research, 1995, Volume: 29, Issue:2

    Topics: Acidosis; Amiloride; Animals; Calcium; Cell Size; Cells, Cultured; Guinea Pigs; Heart; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Male; Myocardium; Protein Kinase C; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate

1995
31P NMR and triple quantum filtered 23Na NMR studies of the effects of inhibition of Na+/H+ exchange on intracellular sodium and pH in working and ischemic hearts.
    Magnetic resonance in medicine, 1994, Volume: 32, Issue:5

    Topics: Acidosis; Amiloride; Animals; Biological Transport, Active; Cardiac Output; Coronary Circulation; Energy Metabolism; Heart Rate; Hydrogen; Hydrogen-Ion Concentration; Ion Transport; Magnetic Resonance Spectroscopy; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Phosphorus Isotopes; Rats; Rats, Sprague-Dawley; Sodium; Sodium Channels; Sodium Isotopes

1994
In vivo adaptation of bicarbonate reabsorption by rat distal tubules during acid loading.
    The American journal of physiology, 1994, Volume: 267, Issue:5 Pt 2

    Topics: Acclimatization; Acidosis; Acute Disease; Amiloride; Ammonium Chloride; Animals; Anti-Bacterial Agents; Anti-Ulcer Agents; Antifungal Agents; Bicarbonates; Chronic Disease; Diet; Fasting; Hydrochloric Acid; Imidazoles; In Vitro Techniques; Infusions, Intravenous; Kidney Tubules, Distal; Macrolides; Male; Perfusion; Proton-Translocating ATPases; Rats; Rats, Sprague-Dawley; Reference Values

1994
Monkey cerebral arterial relaxation caused by hypercapnic acidosis and hypertonic bicarbonate.
    The American journal of physiology, 1993, Volume: 265, Issue:3 Pt 2

    Topics: Acidosis; Adult; Aged; Amiloride; Animals; Bicarbonates; Cerebral Arteries; Chlorides; Female; Humans; Hypercapnia; Hypertonic Solutions; Macaca; Male; Ouabain; Sodium; Vasodilation

1993
Chloride dependent intracellular pH increase induced by bepridil in human red blood cells: a possible involvement in correction of ischemic acidosis.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:3

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acidosis; Amiloride; Bepridil; Calcium; Carbonic Anhydrases; Chlorides; Erythrocytes; Humans; Hydrogen-Ion Concentration; Intracellular Fluid; Ischemia; Magnetic Resonance Spectroscopy; Membrane Potentials; Methazolamide; Phosphorus; Potassium; Sodium; Sodium-Hydrogen Exchangers

1993
H-K-ATPase in distal renal tubular acidosis: urinary tract obstruction, lithium, and amiloride.
    The American journal of physiology, 1993, Volume: 265, Issue:6 Pt 2

    Topics: Acidosis; Aldosterone; Amiloride; Animals; H(+)-K(+)-Exchanging ATPase; Kidney Tubules, Collecting; Kidney Tubules, Distal; Lithium; Male; Rats; Rats, Sprague-Dawley; Ureteral Obstruction

1993
Role of cation gradients in hypercontracture of myocytes during simulated ischemia and reperfusion.
    The American journal of physiology, 1993, Volume: 264, Issue:6 Pt 2

    Topics: Acidosis; Amiloride; Animals; Buffers; Cations; Cell Separation; Coronary Disease; Extracellular Space; Hydrogen-Ion Concentration; Intracellular Membranes; Myocardial Contraction; Myocardial Reperfusion; Myocardium; Osmolar Concentration

1993
pH regulation in perfused rat liver: respective role of Na(+)-H+ exchanger and Na(+)-HCO3- cotransport.
    The American journal of physiology, 1993, Volume: 265, Issue:1 Pt 1

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Acidosis; Amiloride; Animals; Carrier Proteins; Hydrogen-Ion Concentration; Intracellular Membranes; Liver; Magnetic Resonance Spectroscopy; Male; Perfusion; Rats; Rats, Wistar; Sodium-Bicarbonate Symporters; Sodium-Hydrogen Exchangers

1993
Altered Na(+)- H(+)- exchange activity in the spontaneously hypertensive perfused rat heart.
    Journal of molecular and cellular cardiology, 1995, Volume: 27, Issue:8

    Topics: Acidosis; Amiloride; Animals; Carbon Dioxide; Heart; Hydrogen-Ion Concentration; Hypertension; In Vitro Techniques; Kinetics; Male; Myocardium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium; Sodium-Hydrogen Exchangers; Time Factors

1995
pHi in piglet cerebral microvascular endothelial cells: recovery from an acid load.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1996, Volume: 212, Issue:3

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acidosis; Amiloride; Animals; Animals, Newborn; Blood-Brain Barrier; Brain; Carbon Dioxide; Cells, Cultured; Chlorides; Endothelium, Vascular; Hydrogen-Ion Concentration; Hypercapnia; Microcirculation; Propionates; Sodium; Swine

1996
Protective effects of dimethyl amiloride against postischemic myocardial dysfunction in rabbit hearts: phosphorus 31-nuclear magnetic resonance measurements of intracellular pH and cellular energy.
    The Journal of thoracic and cardiovascular surgery, 1996, Volume: 112, Issue:3

    Topics: Acidosis; Adenosine Triphosphate; Amiloride; Animals; Bicarbonates; Calcium; Calcium Chloride; Cardioplegic Solutions; Diastole; Energy Metabolism; Heart; Heart Arrest, Induced; Hydrogen-Ion Concentration; Ischemia; Magnesium; Magnetic Resonance Spectroscopy; Myocardial Contraction; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardium; Phosphates; Phosphocreatine; Phosphorus Isotopes; Potassium Chloride; Rabbits; Sodium; Sodium Chloride; Sodium-Hydrogen Exchangers; Ventricular Function, Left; Ventricular Pressure

1996
Protective effects of extracellular acidosis and blockade of sodium/hydrogen ion exchange during recovery from metabolic inhibition in neuronal tissue culture.
    Journal of neurochemistry, 1996, Volume: 67, Issue:6

    Topics: Acidosis; Amiloride; Animals; Brain Ischemia; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Extracellular Space; Female; Hydrogen; Hydrogen-Ion Concentration; Ionophores; Neuroprotective Agents; Pregnancy; Protons; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sodium; Sodium-Hydrogen Exchangers

1996
Functional roles of apical membrane Na+/H+ exchange in rat medullary thick ascending limb.
    The American journal of physiology, 1996, Volume: 270, Issue:4 Pt 2

    Topics: Absorption; Acidosis; Amiloride; Animals; Bicarbonates; Cell Membrane; Hydrogen-Ion Concentration; Intracellular Membranes; Kidney Medulla; Loop of Henle; Male; Quaternary Ammonium Compounds; Rats; Rats, Sprague-Dawley; Sodium; Sodium-Hydrogen Exchangers

1996
Mechanisms of pHi recovery from NH4Cl-induced acidosis in anoxic isolated turtle heart: a 31P-NMR study.
    The American journal of physiology, 1997, Volume: 272, Issue:1 Pt 2

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acidosis; Amiloride; Ammonium Chloride; Animals; Bicarbonates; Buffers; Carbon Dioxide; Female; Hydrogen; Hydrogen-Ion Concentration; Hypoxia; In Vitro Techniques; Intracellular Membranes; Magnetic Resonance Spectroscopy; Male; Myocardium; Phosphorus; Sodium; Temperature

1997
Short-term inhibition of the Na-H exchanger limits acidosis and reduces ischemic injury in the rat heart.
    Cardiovascular research, 1997, Volume: 34, Issue:2

    Topics: Acidosis; Adenosine Triphosphate; Amiloride; Ammonium Chloride; Animals; Anti-Arrhythmia Agents; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Male; Myocardial Ischemia; Myocardium; Perfusion; Phosphocreatine; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers; Time Factors

1997
Brain tissue acidosis: effects on the extracellular concentration of N-acetylaspartate.
    Journal of neurochemistry, 1997, Volume: 69, Issue:2

    Topics: Acid-Base Equilibrium; Acidosis; Amiloride; Ammonium Chloride; Animals; Aspartic Acid; Brain; Electric Conductivity; Extracellular Space; Hydrogen-Ion Concentration; Hypercapnia; Lactic Acid; Male; Microdialysis; Quaternary Ammonium Compounds; Rats; Rats, Sprague-Dawley

1997
Hypoxia-induced inhibition of the response to nitroxidergic nerve stimulation in canine cerebral arteries.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1997, Volume: 17, Issue:7

    Topics: Acidosis; Amiloride; Animals; Cerebral Arteries; Dogs; Female; Hypoxia; Male; Nervous System Physiological Phenomena; Neural Inhibition; Nitric Oxide; Stimulation, Chemical; Substance P; Superoxide Dismutase

1997
Age-related effects of acidosis in isolated cardiac muscle.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 1998, Volume: 53, Issue:1

    Topics: Acidosis; Aging; Amiloride; Analysis of Variance; Animals; Arrhythmias, Cardiac; Diastole; Diuretics; Electrocardiography; Heart; Hydrogen-Ion Concentration; Hypercapnia; Male; Myocardial Contraction; Myocardial Ischemia; Papillary Muscles; Rats; Rats, Inbred WKY; Sodium; Sodium-Hydrogen Exchangers; Ventricular Dysfunction, Left; Ventricular Pressure

1998
Inhibition of bicarbonate transport protects embryonic heart against reoxygenation-induced dysfunction.
    Journal of molecular and cellular cardiology, 1998, Volume: 30, Issue:2

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acidosis; Amiloride; Animals; Arrhythmias, Cardiac; Bicarbonates; Chick Embryo; Heart; Heart Rate; Hydrogen-Ion Concentration; Ion Transport; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Sodium-Hydrogen Exchangers

1998
Mechanisms of pH preservation during global ischemia in preconditioned rat heart: roles for PKC and NHE.
    The American journal of physiology, 1998, Volume: 275, Issue:3

    Topics: Acidosis; Adenosine Triphosphate; Adrenergic alpha-Agonists; Amiloride; Animals; Guanidines; Hydrogen-Ion Concentration; Ischemic Preconditioning, Myocardial; Kinetics; Male; Myocardial Ischemia; Phenylephrine; Phosphates; Protein Kinase C; Rats; Rats, Sprague-Dawley; Signal Transduction; Sodium-Hydrogen Exchangers; Sulfones

1998
Cytosolic pH regulation in perfused rat liver: role of intracellular bicarbonate production.
    Biochimica et biophysica acta, 1998, Sep-16, Volume: 1425, Issue:1

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Acetazolamide; Acidosis; Amiloride; Animals; Bicarbonates; Cytosol; Homeostasis; Hydrogen-Ion Concentration; In Vitro Techniques; Intracellular Fluid; Liver; Magnetic Resonance Spectroscopy; Male; Perfusion; Rats; Rats, Wistar

1998
Regulation of intracellular pH in hamster preimplantation embryos by the sodium hydrogen (Na+/H+) antiporter.
    Biology of reproduction, 1998, Volume: 59, Issue:6

    Topics: Acid-Base Equilibrium; Acidosis; Amiloride; Animals; Antiporters; Chloride-Bicarbonate Antiporters; Cleavage Stage, Ovum; Cricetinae; Culture Media; Culture Techniques; Embryo, Mammalian; Embryonic Development; Female; Hydrogen-Ion Concentration; Mesocricetus; Pregnancy; Proton-Translocating ATPases; Sodium; Sodium-Hydrogen Exchangers

1998
pH dependence of corneal oxygen consumption.
    Investigative ophthalmology & visual science, 1998, Volume: 39, Issue:13

    Topics: Acidosis; Amiloride; Animals; Cornea; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Ouabain; Oxygen; Oxygen Consumption; Porphyrins; Rabbits; Sodium-Hydrogen Exchangers

1998
Ethyl isopropylamiloride downregulates Na,K-ATPase gene expression which confers cytotoxicity in primary proximal tubule cell cultures.
    The Chinese journal of physiology, 1998, Dec-31, Volume: 41, Issue:4

    Topics: Acidosis; Amiloride; Animals; Anti-Arrhythmia Agents; Blotting, Northern; Cell Survival; Cells, Cultured; Enzyme Activation; Gene Expression Regulation, Enzymologic; Hydrogen-Ion Concentration; Kidney Tubules, Proximal; L-Lactate Dehydrogenase; Rabbits; RNA, Messenger; Sodium-Potassium-Exchanging ATPase

1998
Inhibition of Na+-H+ exchanger protects diabetic and non-diabetic hearts from ischemic injury: insight into altered susceptibility of diabetic hearts to ischemic injury.
    Journal of molecular and cellular cardiology, 1999, Volume: 31, Issue:4

    Topics: Acidosis; Adenosine Triphosphate; Amiloride; Animals; Calcium; Diabetes Mellitus, Type 1; Hydrogen-Ion Concentration; In Vitro Techniques; Intracellular Fluid; Magnetic Resonance Spectroscopy; Myocardial Reperfusion Injury; Phosphocreatine; Quaternary Ammonium Compounds; Rats; Rats, Inbred BB; Sodium; Sodium-Hydrogen Exchangers

1999
Changes in intracellular Na+ and pH in rat heart during ischemia: role of Na+/H+ exchanger.
    The American journal of physiology, 1999, Volume: 276, Issue:5

    Topics: Acidosis; Amiloride; Animals; Benzofurans; Benzopyrans; Ethers, Cyclic; Female; Fluorescent Dyes; Heart Ventricles; Hydrogen-Ion Concentration; Hypoxia; Muscle Fibers, Skeletal; Myocardial Ischemia; Myocardium; Naphthols; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Rhodamines; Sodium; Sodium Lactate; Sodium-Hydrogen Exchangers; Ventricular Function, Left

1999
Na+ :H+ exchange inhibition induces intracellular acidosis and differentially impairs cell growth and viability of human and rat hepatocarcinoma cells.
    Toxicology letters, 1999, Jun-01, Volume: 106, Issue:2-3

    Topics: Acidosis; Amiloride; Animals; Antineoplastic Agents; Calcium; Carcinoma, Hepatocellular; Cell Division; Cell Survival; DNA; Dose-Response Relationship, Drug; Humans; Liver Neoplasms; Rats; Sodium; Tumor Cells, Cultured

1999
Nisoldipine selectively induces coronary vasodilation and improves mild myocardial ischemia in dogs: a potential role of cellular acidosis.
    Cardiovascular drugs and therapy, 1998, Volume: 12, Issue:6

    Topics: Acidosis; Amiloride; Animals; Bicarbonates; Blood Pressure; Buffers; Coronary Circulation; Diuretics; Dogs; In Vitro Techniques; Injections, Intravenous; Myocardial Ischemia; Nisoldipine; Oxygen; Vasodilator Agents

1998
Effect of lactacidosis on cell volume and intracellular pH of astrocytes.
    Journal of neurotrauma, 1999, Volume: 16, Issue:9

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Acidosis; Amiloride; Animals; Animals, Newborn; Astrocytes; Cell Size; Cells, Cultured; Diuretics; Hydrogen-Ion Concentration; Intracellular Fluid; Lactic Acid; Rats; Rats, Sprague-Dawley

1999
Proton-gated ion channels in cultured mouse cortical neurons.
    Neuropharmacology, 1999, Volume: 38, Issue:12

    Topics: Acidosis; Action Potentials; Amiloride; Animals; Brain Ischemia; Cells, Cultured; Diuretics; Extracellular Space; Ion Channel Gating; Mice; Neocortex; Patch-Clamp Techniques; Protons

1999
Role of Na+/H+ exchange and HCO3- transport in pHi recovery from intracellular acid load in cultured epithelial cells of sheep rumen.
    Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2000, Volume: 170, Issue:4

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acidosis; Amiloride; Animals; Anti-Arrhythmia Agents; Bicarbonates; Biological Transport; Butyrates; Carbon Dioxide; Cell Culture Techniques; Cells, Cultured; Epithelial Cells; Fluoresceins; Guanidines; Hydrogen-Ion Concentration; Rumen; Sheep; Sodium-Hydrogen Exchangers; Sulfones

2000
Intracellular pH regulation in neurons from chemosensitive and nonchemosensitive regions of Helix aspersa.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2000, Volume: 279, Issue:2

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acidosis; Amiloride; Ammonium Chloride; Animals; Chemoreceptor Cells; Chloride Channels; Helix, Snails; Hydrogen; Hydrogen-Ion Concentration; Hypercapnia; Intracellular Membranes; Neurons; Sodium-Hydrogen Exchangers

2000
Inhibition of Na(+)/H(+) exchange by 5-(N-ethyl-N-isopropyl)-amiloride reduces free fatty acid efflux from the ischemic reperfused rat cerebral cortex.
    Brain research, 2000, Nov-24, Volume: 884, Issue:1--2

    Topics: Acidosis; Amiloride; Animals; Brain Ischemia; Cardiovascular Physiological Phenomena; Cerebral Cortex; Electroencephalography; Fatty Acids, Nonesterified; Glucose; Lactic Acid; Male; Neuroprotective Agents; Phospholipases; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sodium-Hydrogen Exchangers

2000
The effect of acidosis on systolic Ca2+ and sarcoplasmic reticulum calcium content in isolated rat ventricular myocytes.
    The Journal of physiology, 2000, Dec-15, Volume: 529 Pt 3

    Topics: Acidosis; Amiloride; Animals; Butyrates; Caffeine; Calcium; Calcium Channels, L-Type; Cell Separation; Heart Ventricles; Hydrogen-Ion Concentration; Myocardium; Rats; Sarcoplasmic Reticulum; Sodium-Calcium Exchanger; Systole

2000
pH paradox and neonatal heart.
    The Journal of cardiovascular surgery, 2001, Volume: 42, Issue:4

    Topics: Acidosis; Amiloride; Animals; Animals, Newborn; Blood Pressure; Calcium; Diastole; Female; Heart Arrest, Induced; Hydrogen; Hydrogen-Ion Concentration; Male; Myocardial Reperfusion Injury; Myocardium; Rabbits; Sodium; Sodium-Hydrogen Exchangers; Temperature

2001
Developmental changes in intracellular pH regulation in medullary neurons of the rat.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2001, Volume: 281, Issue:6

    Topics: Acidosis; Aging; Amiloride; Ammonia; Animals; Animals, Newborn; Carbon Dioxide; Female; Fluoresceins; Fluorescent Dyes; Homeostasis; Hydrogen-Ion Concentration; Hypoglossal Nerve; In Vitro Techniques; Intracellular Fluid; Male; Medulla Oblongata; Neurons; Nigericin; Rats; Rats, Sprague-Dawley

2001
Endothelin reverses the effects of acidosis on the intracellular Ca2+ transient and contractility in ferret myocardium.
    Circulation research, 1992, Volume: 71, Issue:3

    Topics: Acidosis; Amiloride; Animals; Calcium; Cardiotonic Agents; Coronary Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelins; Ferrets; Heart; Hydrogen-Ion Concentration; In Vitro Techniques; Ion Pumps; Myocardial Contraction; Time Factors

1992
Phenylephrine and ATP enhance an amiloride insensitive bicarbonate-dependent alkalinizing mechanism in rat single cardiomyocytes.
    Naunyn-Schmiedeberg's archives of pharmacology, 1992, Volume: 346, Issue:5

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acidosis; Adenosine Triphosphate; Amiloride; Animals; Bicarbonates; Culture Media; Heart; Hydrogen-Ion Concentration; In Vitro Techniques; Myocardium; Phenylephrine; Rats; Rats, Wistar; Receptors, Adrenergic, alpha

1992
[The arrhythmogenicity of alpha 1-adrenergic stimulation following myocardial acidosis].
    Cardiologia (Rome, Italy), 1992, Volume: 37, Issue:8

    Topics: Acidosis; Amiloride; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzopyrans; Cardiomyopathies; Fluorescence; Fluorescent Dyes; Heart; Hydrogen-Ion Concentration; In Vitro Techniques; Myocardial Contraction; Rats; Receptors, Adrenergic, alpha

1992
Contraction and intracellular Ca2+, Na+, and H+ during acidosis in rat ventricular myocytes.
    The American journal of physiology, 1992, Volume: 262, Issue:2 Pt 1

    Topics: Acidosis; Acidosis, Respiratory; Amiloride; Animals; Calcium; Heart Ventricles; Hydrogen; Hydrogen-Ion Concentration; Intracellular Membranes; Ions; Myocardial Contraction; Myocardium; Rats; Ryanodine; Sarcoplasmic Reticulum; Sodium

1992
Induction of stress proteins in cultured myogenic cells. Molecular signals for the activation of heat shock transcription factor during ischemia.
    The Journal of clinical investigation, 1992, Volume: 89, Issue:5

    Topics: Acidosis; Adenosine Triphosphate; Amiloride; Base Sequence; Cells, Cultured; DNA-Binding Proteins; Glucose; Heat-Shock Proteins; In Vitro Techniques; Molecular Sequence Data; Muscles; Oligodeoxyribonucleotides; Oxidative Phosphorylation; Propionates; Regulatory Sequences, Nucleic Acid; Rotenone; Transcription Factors

1992
Signal transduction events whereby PGF2 alpha inhibits the ammoniagenic response to acute acidosis.
    The American journal of physiology, 1992, Volume: 262, Issue:6 Pt 2

    Topics: Acidosis; Acute Disease; Alanine; Amiloride; Ammonia; Animals; Calcium Channel Blockers; Cell Line; Dinoprostone; Egtazic Acid; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate

1992
Mechanism of ammonium transport by intestinal segments following urinary diversion: evidence for ionized NH4+ transport via K(+)-pathways.
    The Journal of urology, 1992, Volume: 148, Issue:2 Pt 1

    Topics: Acidosis; Amiloride; Ammonia; Animals; Barium; Biological Transport; Dimethyl Sulfoxide; Furosemide; Hydrogen-Ion Concentration; Ileum; Intestinal Absorption; Male; Methylprednisolone; Potassium; Pyrimidines; Rats; Rats, Inbred Strains; Urinary Diversion

1992
Differential regulation of Na/H antiporter by acid in renal epithelial cells and fibroblasts.
    The Journal of clinical investigation, 1991, Volume: 88, Issue:5

    Topics: Acidosis; Amiloride; Animals; Carrier Proteins; Cells, Cultured; Epithelium; Kidney; Mice; Phosphoenolpyruvate Carboxykinase (GTP); Rabbits; RNA, Messenger; Sodium-Hydrogen Exchangers

1991
Effect of partial Na pump and Na-H exchange inhibition on [Ca]i during acidosis in cardiac cells.
    The American journal of physiology, 1991, Volume: 261, Issue:5 Pt 1

    Topics: Acidosis; Amiloride; Animals; Calcium; Carrier Proteins; Cell Separation; Hydrogen-Ion Concentration; Myocardial Contraction; Myocardium; Osmolar Concentration; Ouabain; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase

1991
Sodium-hydrogen exchange in guinea-pig ventricular muscle during exposure to hyperosmolar solutions.
    The Journal of physiology, 1991, Volume: 444

    Topics: Acidosis; Alkalosis; Amiloride; Animals; Guinea Pigs; Heart Ventricles; Hydrogen-Ion Concentration; In Vitro Techniques; Ion Exchange; Microelectrodes; Muscles; Osmolar Concentration; Protons; Sarcolemma; Sodium; Sodium-Potassium-Exchanging ATPase; Solutions; Ventricular Function

1991
Role of Na-H exchange in the inotropic action of Bay K 8644 and of ouabain in guinea-pig isolated atria.
    British journal of pharmacology, 1990, Volume: 100, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acidosis; Amiloride; Animals; Calcium; Guinea Pigs; Heart; Hydrogen; Hydrogen-Ion Concentration; In Vitro Techniques; Ion Exchange; Myocardial Contraction; Myocardium; Ouabain; Sodium

1990
H(+)-K(+)-ATPase contributes to regulation of pHi in frog oxynticopeptic cells.
    The American journal of physiology, 1991, Volume: 261, Issue:5 Pt 1

    Topics: Acidosis; Adenosine Triphosphatases; Amiloride; Animals; Gastric Mucosa; H(+)-K(+)-Exchanging ATPase; Histamine Release; Hydrogen-Ion Concentration; Intracellular Membranes; Parietal Cells, Gastric; Rana catesbeiana; Serous Membrane

1991
Na(+)-H+ exchange in choroid plexus and CSF in acute metabolic acidosis or alkalosis.
    The American journal of physiology, 1990, Volume: 258, Issue:6 Pt 2

    Topics: Acid-Base Equilibrium; Acidosis; Acute Disease; Alkalosis; Amiloride; Animals; Antipyrine; Arteries; Carrier Proteins; Cell Membrane; Central Nervous System; Choroid Plexus; Electrolytes; Extracellular Space; Hydrogen; Male; Rats; Rats, Inbred Strains; Sodium; Sodium-Hydrogen Exchangers

1990
Molecular mechanisms of glial cell swelling in acidosis.
    Advances in neurology, 1990, Volume: 52

    Topics: Acetazolamide; Acidosis; Amiloride; Animals; Bicarbonates; Brain Neoplasms; Carrier Proteins; Cell Survival; Glioma; HEPES; Hydrogen-Ion Concentration; Neuroglia; Rats; Sodium-Hydrogen Exchangers; Tumor Cells, Cultured

1990
Effects of extracellular acidosis on the action of smooth muscle relaxants.
    Proceedings of the Western Pharmacology Society, 1990, Volume: 33

    Topics: Acidosis; Albuterol; Amiloride; Animals; Carbachol; Dogs; In Vitro Techniques; Isometric Contraction; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Trachea

1990
Effect of acid-base balance on biliary bicarbonate secretion in the isolated perfused guinea pig liver.
    The American journal of physiology, 1990, Volume: 258, Issue:6 Pt 1

    Topics: Acid-Base Equilibrium; Acidosis; Acidosis, Respiratory; Alkalosis; Alkalosis, Respiratory; Amiloride; Animals; Bicarbonates; Bile; Electrolytes; Guinea Pigs; In Vitro Techniques; Liver; Male; Perfusion; Reference Values

1990
Intracellular pH during "chemical hypoxia" in cultured rat hepatocytes. Protection by intracellular acidosis against the onset of cell death.
    The Journal of clinical investigation, 1989, Volume: 83, Issue:2

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acidosis; Amiloride; Animals; Bicarbonates; Carrier Proteins; Cell Survival; Cells, Cultured; Chlorides; Fluoresceins; Gluconates; Hydrogen-Ion Concentration; Liver; Male; Monensin; Oxygen; Rats; Rats, Inbred Strains; Sodium-Hydrogen Exchangers

1989
Determinants of ammonia entry along the rat proximal tubule during chronic metabolic acidosis.
    The American journal of physiology, 1989, Volume: 256, Issue:6 Pt 2

    Topics: Acidosis; Amiloride; Ammonia; Animals; Bicarbonates; Kidney Tubules, Proximal; Perfusion; Rats; Rats, Inbred Strains

1989
Amiloride prevents the metabolic acidosis of a KCl load in nephrectomized rats.
    Clinical science (London, England : 1979), 1989, Volume: 76, Issue:6

    Topics: Acidosis; Amiloride; Animals; Hydrogen; Male; Nephrectomy; Potassium; Potassium Chloride; Rats; Rats, Inbred Strains; Sodium

1989
Differentiation of Na+-K+ pump in rat proximal tubule is modulated by Na+-H+ exchanger.
    The American journal of physiology, 1988, Volume: 255, Issue:3 Pt 2

    Topics: Acidosis; Aging; Amiloride; Ammonium Chloride; Animals; Carrier Proteins; DNA; In Vitro Techniques; Kidney; Kidney Tubules, Proximal; Male; Proteins; Rats; Rats, Inbred Strains; Reference Values; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase

1988
Acidosis, acetazolamide, and amiloride: effects on 22Na transfer across the blood-brain and blood-CSF barriers.
    Journal of neurochemistry, 1989, Volume: 52, Issue:4

    Topics: Acetazolamide; Acidosis; Amiloride; Animals; Blood-Brain Barrier; Brain; Cerebrospinal Fluid; Male; Rats; Rats, Inbred Strains; Sodium; Sodium Radioisotopes; Tissue Distribution

1989
Intact ability to lower urine pH in nonacidotic adrenalectomized rats.
    Mineral and electrolyte metabolism, 1986, Volume: 12, Issue:2

    Topics: Acidosis; Adrenalectomy; Aldosterone; Amiloride; Animals; Bicarbonates; Dexamethasone; Hydrogen-Ion Concentration; Male; Rats; Rats, Inbred Strains; Sodium; Sodium Bicarbonate; Sodium Chloride; Sulfates; Urine

1986
Effect of amiloride on contractility of rat cardiac muscle exposed to chronic hypercapnia and acute acidosis.
    Cardiovascular research, 1988, Volume: 22, Issue:11

    Topics: Acidosis; Amiloride; Animals; Hydrogen-Ion Concentration; Hypercapnia; In Vitro Techniques; Myocardial Contraction; Papillary Muscles; Rats; Rats, Inbred Strains; Time Factors

1988
Glial swelling during extracellular acidosis in vitro.
    Stroke, 1988, Volume: 19, Issue:3

    Topics: Acidosis; Alkalosis; Amiloride; Extracellular Space; HEPES; Hydrogen-Ion Concentration; Neuroglia; Tumor Cells, Cultured

1988
Characteristics of proton excretion in normal and acidotic toad urinary bladder.
    Biochimica et biophysica acta, 1985, Jul-11, Volume: 817, Issue:1

    Topics: Acidosis; Amiloride; Animals; Bufo marinus; Carbon Dioxide; Hydrogen-Ion Concentration; Kinetics; Models, Biological; Mucous Membrane; Urinary Bladder

1985
Role of carbonic anhydrase in urinary acidification by the toad bladder.
    The American journal of physiology, 1974, Volume: 227, Issue:5

    Topics: Acetazolamide; Acidosis; Amiloride; Ammonium Chloride; Animals; Biological Transport; Bufo marinus; Carbon Dioxide; Carbonic Anhydrases; Depression, Chemical; Electrophysiology; Hydrogen-Ion Concentration; Membrane Potentials; Partial Pressure; Sodium; Species Specificity; Urinary Bladder; Urine

1974
Prevention of diuretic-induced electrolyte disturbances by amiloride in patients with ascites due to cirrhosis of the liver.
    Acta cardiologica, 1973

    Topics: Acidosis; Alkalosis; Amiloride; Ascites; Diuretics; Humans; Hypokalemia; Hyponatremia; Liver Cirrhosis; Pyrazines; Water-Electrolyte Balance

1973
The effect of potassium metabolism on acetazolamide-induced teratogenesis.
    The Johns Hopkins medical journal, 1972, Volume: 130, Issue:2

    Topics: Abnormalities, Drug-Induced; Acetazolamide; Acidosis; Administration, Oral; Amiloride; Animals; Bicarbonates; Female; Forelimb; Injections, Subcutaneous; Kidney; Liver; Muscles; Potassium; Potassium Deficiency; Pregnancy; Pregnancy Complications; Rats; Sodium; Triamterene

1972
Potassium-escape-phenomenon in rats during continuous application of amiloride. 3. Influence of acid and alkali loading.
    Pharmacology, 1971, Volume: 6, Issue:5

    Topics: Acid-Base Equilibrium; Acidosis; Alkalosis; Amiloride; Ammonium Chloride; Animals; Bicarbonates; Diuresis; Diuretics; Hydrogen-Ion Concentration; Male; Nephrectomy; Potassium; Pyrazines; Rats; Rats, Inbred Strains; Sodium; Sodium Chloride; Urea

1971