amiloride has been researched along with Invasiveness, Neoplasm in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (11.76) | 18.2507 |
| 2000's | 10 (58.82) | 29.6817 |
| 2010's | 4 (23.53) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Aboelela, A; Buckley, BJ; Bujaroski, RS; Fliegel, L; Kelso, MJ; Kumar, A; Li, X; Majed, H; Ranson, M | 1 |
| Ji, HL; Li, X; Liu, C; Ma, Y; Xu, S | 1 |
| Andrews, EJ; Killeen, SD; Redmond, HP; Wang, JH | 1 |
| Dong, W; Dou, K; Song, Z; Wang, D; Yang, X | 2 |
| Chan, WL; Chang, JG; Chang, WH; Chang, YS; Chow, LP; Huang, HD; Hung, CH; Lin, HH; Yang, DM; Yang, WK | 1 |
| Izaki, H; Kagawa, S; Kanayama, HO; Kido, H; Oka, N; Okamoto, M; Okumura, Y | 1 |
| Bourguignon, LY; Diedrich, F; Gilad, E; Singleton, PA; Stern, R | 1 |
| Jones, DA; Kassis, J; Kharait, S; Kloeker, S; Mamoune, A; Manos, E; Wells, A | 1 |
| Evans, DM; Sloan Stakleff, KD | 1 |
| Bauer, TW; Boyd, DD; Bucana, CD; Callahan, J; Camp, ER; Ellis, LM; Evans, DB; Fan, F; Liu, W; Mazar, AP; Parry, GC; Somcio, RJ; Yang, A | 1 |
| Sinha, AA; Wilson, MJ | 1 |
| Alonso, DF; Bal de Kier Joffé, E; Davel, L; Farías, EF; Ladeda, V; Puricelli, L | 1 |
| Albarani, V; Bellizzi, A; Casavola, V; Guerra, L; Paradiso, A; Reshkin, SJ; Tommasino, M | 1 |
| Evans, DM; Sloan-Stakleff, K | 1 |
| Arroyo de Prada, N; Graeff, H; Luther, T; Magdolen, U; Magdolen, V; Muehlenweg, B; Reuning, U; Schmitt, M; Sperl, S; Wilhelm, OG | 1 |
| Akedo, H; Iwasaki, T; Kakishita, E; Mukai, M; Nakata, A; Sabe, H; Schaefer, E; Shinkai, K; Tatsuta, M; Terada, N; Tsujimura, T; Yano, H | 1 |
2 review(s) available for amiloride and Invasiveness, Neoplasm
| Article | Year |
|---|---|
Potential Roles of Amiloride-Sensitive Sodium Channels in Cancer Development.
Topics: Acid Sensing Ion Channels; Amiloride; Animals; Apoptosis; Cell Movement; Cell Proliferation; Epithelial Sodium Channels; Humans; Neoplasm Invasiveness; Neoplasms; Signal Transduction; Sodium | 2016 |
Natural and synthetic inhibitors of the tumor-associated serine protease urokinase-type plasminogen activator.
Topics: Amidines; Amiloride; Animals; Benzamidines; Guanidines; Mice; Mice, Knockout; Models, Biological; Molecular Structure; Neoplasm Invasiveness; Neoplasm Proteins; Phenotype; Plasminogen Activator Inhibitor 1; Plasminogen Activator Inhibitor 2; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; Serine Proteinase Inhibitors; Serpins; Structure-Activity Relationship; Thiophenes; Urokinase-Type Plasminogen Activator | 2000 |
15 other study(ies) available for amiloride and Invasiveness, Neoplasm
| Article | Year |
|---|---|
Screening of 5- and 6-Substituted Amiloride Libraries Identifies Dual-uPA/NHE1 Active and Single Target-Selective Inhibitors.
Topics: Amiloride; Breast Neoplasms; Cell Line, Tumor; Diuretics; Female; Humans; Models, Molecular; Neoplasm Invasiveness; Sodium-Hydrogen Exchanger 1; Structure-Activity Relationship; Urokinase-Type Plasminogen Activator | 2021 |
Bacterial endotoxin enhances colorectal cancer cell adhesion and invasion through TLR-4 and NF-kappaB-dependent activation of the urokinase plasminogen activator system.
Topics: Amiloride; Antibodies; Bacterial Toxins; Caco-2 Cells; Carcinoma; Cell Adhesion; Cell Movement; Colorectal Neoplasms; Humans; Lipopolysaccharides; Neoplasm Invasiveness; NF-kappa B; Receptors, Urokinase Plasminogen Activator; Toll-Like Receptor 4; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator | 2009 |
Inhibition of Na(+)/H(+) exchanger 1 by 5-(N-ethyl-N-isopropyl) amiloride reduces hypoxia-induced hepatocellular carcinoma invasion and motility.
Topics: Amiloride; Carcinoma, Hepatocellular; Cation Transport Proteins; Cell Hypoxia; Cell Movement; Extracellular Signal-Regulated MAP Kinases; Hep G2 Cells; Humans; Hydrogen-Ion Concentration; Liver Neoplasms; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers; Vascular Endothelial Growth Factor A | 2010 |
Expression and modulation of Na(+) /H(+) exchanger 1 gene in hepatocellular carcinoma: A potential therapeutic target.
Topics: Adult; Aged; Aged, 80 and over; Amiloride; Animals; Apoptosis; Carcinoma, Hepatocellular; Cation Transport Proteins; Cell Proliferation; Female; Flow Cytometry; Gene Expression Regulation, Neoplastic; Genetic Therapy; Hep G2 Cells; Humans; Hydrogen-Ion Concentration; Immunohistochemistry; Liver Neoplasms; Male; Mice; Mice, Nude; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; RNA Interference; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers; Spectrometry, Fluorescence; Time Factors; Transfection; Tumor Burden; Up-Regulation; Xenograft Model Antitumor Assays | 2011 |
Small molecule amiloride modulates oncogenic RNA alternative splicing to devitalize human cancer cells.
Topics: Alternative Splicing; Amiloride; Apoptosis; Cell Line, Tumor; Cell Nucleus; Cytokinesis; Cytoskeleton; DNA Fragmentation; DNA Repair; Enzyme Activation; Exons; Gene Expression Regulation, Neoplastic; Genes, Neoplasm; Genome, Human; Humans; Mitosis; Neoplasm Invasiveness; Neoplasm Proteins; Neoplasms; Nuclear Proteins; Phosphorylation; Protein Isoforms; Protein Phosphatase 1; Proteomics; Proto-Oncogene Proteins c-akt; RNA-Binding Proteins; RNA, Messenger; RNA, Neoplasm; Serine-Arginine Splicing Factors | 2011 |
Amiloride and urinary trypsin inhibitor inhibit urothelial cancer invasion.
Topics: Amiloride; Carcinoma, Transitional Cell; Cell Line, Tumor; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Neoplasm Invasiveness; RNA, Messenger; Sensitivity and Specificity; Trypsin Inhibitors; Urokinase-Type Plasminogen Activator; Urothelium | 2003 |
CD44 interaction with Na+-H+ exchanger (NHE1) creates acidic microenvironments leading to hyaluronidase-2 and cathepsin B activation and breast tumor cell invasion.
Topics: Amides; Amiloride; Animals; Breast Neoplasms; Cathepsin B; Caveolin 1; Caveolins; Cell Line, Tumor; Endosomes; Enzyme Inhibitors; Humans; Hyaluronan Receptors; Hyaluronic Acid; Hyaluronoglucosaminidase; Hydrogen-Ion Concentration; Immunoglobulin G; Intracellular Signaling Peptides and Proteins; Lysosomes; Membrane Microdomains; Membrane Proteins; Neoplasm Invasiveness; Phosphorylation; Protein Serine-Threonine Kinases; Pyridines; Rats; rho-Associated Kinases; RNA, Small Interfering; Sodium-Hydrogen Exchangers | 2004 |
DU145 human prostate carcinoma invasiveness is modulated by urokinase receptor (uPAR) downstream of epidermal growth factor receptor (EGFR) signaling.
Topics: Amiloride; Animals; Antisense Elements (Genetics); Autocrine Communication; Carcinoma; Cell Movement; DNA, Complementary; Down-Regulation; Epidermal Growth Factor; ErbB Receptors; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Phospholipase C gamma; Prostatic Neoplasms; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; Signal Transduction; Type C Phospholipases; Up-Regulation; Urokinase-Type Plasminogen Activator; Xenograft Model Antitumor Assays | 2004 |
Control of pulmonary metastases of rat mammary cancer by inhibition of uPA and COX-2, singly and in combination.
Topics: Amiloride; Animals; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Drug Therapy, Combination; Female; Isoenzymes; Lung Neoplasms; Mammary Neoplasms, Experimental; Neoplasm Invasiveness; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Inbred F344; Sulfonamides; Urokinase-Type Plasminogen Activator | 2004 |
Targeting of urokinase plasminogen activator receptor in human pancreatic carcinoma cells inhibits c-Met- and insulin-like growth factor-I receptor-mediated migration and invasion and orthotopic tumor growth in mice.
Topics: Amiloride; Animals; Antibodies, Monoclonal; Apoptosis; Cell Growth Processes; Cell Line, Tumor; Cell Movement; Hepatocyte Growth Factor; Humans; Insulin-Like Growth Factor I; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Neovascularization, Pathologic; Pancreatic Neoplasms; Proto-Oncogene Proteins c-met; Receptor, IGF Type 1; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; Urokinase-Type Plasminogen Activator | 2005 |
Plasminogen activator and metalloprotease activities of Du-145, PC-3, and 1-LN-PC-3-1A human prostate tumors grown in nude mice: correlation with tumor invasive behavior.
Topics: Amiloride; Animals; Humans; Male; Metalloendopeptidases; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Neoplasm Transplantation; Plasminogen Activators; Prostatic Neoplasms; Transplantation, Heterologous; Urokinase-Type Plasminogen Activator | 1993 |
Effects of synthetic urokinase inhibitors on local invasion and metastasis in a murine mammary tumor model.
Topics: Amidines; Amiloride; Animals; Antineoplastic Agents; Cell Division; Diuretics; Enzyme Inhibitors; Female; Fibrinolysis; Fibronectins; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Neoplasm Invasiveness; Neoplasm Metastasis; Neovascularization, Pathologic; Thiophenes; Triamterene; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator | 1996 |
Phosphoinositide 3-kinase is involved in the tumor-specific activation of human breast cancer cell Na(+)/H(+) exchange, motility, and invasion induced by serum deprivation.
Topics: Adenosine Triphosphate; Amiloride; Ammonium Chloride; Androstadienes; Blood; Blotting, Western; Breast Neoplasms; Cell Line; Cell Movement; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Kinetics; Lactic Acid; Neoplasm Invasiveness; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Sodium-Hydrogen Exchangers; Time Factors; Transfection; Tumor Cells, Cultured; Up-Regulation; Wortmannin | 2000 |
Suppression of the invasive capacity of human breast cancer cells by inhibition of urokinase plasminogen activator via amiloride and B428.
Topics: Amidines; Amiloride; Breast Neoplasms; Cell Division; Humans; Neoplasm Invasiveness; Serine Proteinase Inhibitors; Thiophenes; Tumor Cells, Cultured | 2000 |
Involvement of phosphorylation of Tyr-31 and Tyr-118 of paxillin in MM1 cancer cell migration.
Topics: Amiloride; Animals; Blotting, Western; Cell Movement; Cytoskeletal Proteins; Dose-Response Relationship, Drug; Fibronectins; Immunoblotting; Lysophospholipids; Neoplasm Invasiveness; Paxillin; Phosphoproteins; Phosphorylation; Phosphotyrosine; Precipitin Tests; Pseudopodia; Rats; Serine Endopeptidases; Signal Transduction; Time Factors; Tumor Cells, Cultured; Tyrosine | 2002 |