amiloride and Disease Models, Animal

Topics: Amiloride; Animals; Anticonvulsants; Brain; Disease Models, Animal; Enzyme Inhibitors; Epilepsy; Humans; Sodium Channel Blockers; Sodium Channels; Sodium-Hydrogen Exchangers

Topics: Amiloride; Animals; Diet, Sodium-Restricted; Disease Models, Animal; Dogs; Edema; Epithelial Sodium Channel Blockers; Epithelial Sodium Channels; Humans; Hypoalbuminemia; Kidney Glomerulus; Kidney Tubules, Collecting; Natriuresis; Nephrotic Syndrome; Proteinuria; Rats; Rats, Mutant Strains; Serine Proteases; Sodium; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase

Topics: Administration, Oral; Amiloride; Animals; Antineoplastic Agents; Disease Models, Animal; Humans; Neoplasm Metastasis; Neoplasms; Sodium Channel Blockers; Sodium-Hydrogen Exchangers; Urokinase-Type Plasminogen Activator

Topics: Acidosis, Renal Tubular; Amiloride; Amphibians; Amphotericin B; Animals; Biological Transport, Active; Carbonates; Disease Models, Animal; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Kidney Tubules; Kidney Tubules, Distal; Lithium; Membrane Potentials; Rats; Turtles

Topics: Acidosis, Renal Tubular; Aldosterone; Amiloride; Amphotericin B; Animals; Carbon Dioxide; Disease Models, Animal; Hydrogen; Hydrogen-Ion Concentration; Kidney Tubules, Distal; Lithium; Partial Pressure; Ureteral Obstruction

Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis

Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, Spinal; Humans; Mice, Inbred C57BL; Mice, Knockout; Neurons; Pruritus; Receptors, Atrial Natriuretic Factor; Reproducibility of Results; Signal Transduction; Small Molecule Libraries

Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

Topics: Acid Sensing Ion Channels; Amiloride; Animals; Disease Models, Animal; Injections, Intraperitoneal; Locomotion; Male; Nociception; Visceral Pain; Zebrafish

Topics: 1-Methyl-3-isobutylxanthine; Amiloride; Animals; Animals, Genetically Modified; Colforsin; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Disease Models, Animal; Epithelial Sodium Channel Blockers; Epithelial Sodium Channels; Epithelium; Ion Transport; Male; Sodium; Swine

Topics: Amiloride; Animals; Aquaporin 2; Autonomic Denervation; Chronic Disease; Disease Models, Animal; Diuretics; Epithelial Sodium Channel Blockers; Epithelial Sodium Channels; Heart Failure; Kidney; Male; Natriuresis; Rats, Sprague-Dawley; Renal Elimination; Sodium

Topics: Acidosis; Amiloride; Animals; Brain Ischemia; Cell Death; Disease Models, Animal; Epithelial Sodium Channel Blockers; Hippocampus; Injections, Intraperitoneal; Male; Mice; Neurons; Oxidative Stress; Zinc

Topics: Acetanilides; Acid Sensing Ion Channel Blockers; Acid Sensing Ion Channels; Acrylamides; Amiloride; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bridged Bicyclo Compounds, Heterocyclic; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; Hyperalgesia; Male; Mice; Morphine; Pain Measurement; Purines; Random Allocation; Receptors, Atrial Natriuretic Factor; Receptors, Opioid; Stomach Ulcer; Transient Receptor Potential Channels; Visceral Pain

Topics: Acetic Acid; Acid Sensing Ion Channel Blockers; Acid Sensing Ion Channels; Acrylamides; Amiloride; Animals; Behavior, Animal; Bridged Bicyclo Compounds, Heterocyclic; Calcitonin Gene-Related Peptide; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Pain; Phosphorylation; Proto-Oncogene Proteins c-fos; Trigeminal Nucleus, Spinal; TRPV Cation Channels

Topics: Acid Sensing Ion Channels; Amiloride; Animals; Disease Models, Animal; Elapid Venoms; Hyperalgesia; Injections, Intravenous; Male; Mice; Mice, Inbred C57BL; Migraine Disorders; Peptides; Rats; Rats, Sprague-Dawley

Topics: Amiloride; Animals; Blood Pressure; Disease Models, Animal; Epidermal Growth Factor; Epithelial Sodium Channels; Hypertension; Kidney; Rats; Rats, Inbred Dahl; Sodium Chloride, Dietary

Topics: Acid Sensing Ion Channel Blockers; Acid Sensing Ion Channels; Amiloride; Animals; Disease Models, Animal; Ganglia, Spinal; Hyperalgesia; Irritable Bowel Syndrome; Male; Nerve Growth Factor; Pain Measurement; Rats; Rats, Sprague-Dawley

Topics: Acid Sensing Ion Channels; Amiloride; Analgesics; Animals; Disease Models, Animal; Male; Neuralgia; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spinal Cord; Transcription, Genetic

Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acid Sensing Ion Channel Blockers; Acid Sensing Ion Channels; Amiloride; Animals; Carrier Proteins; Cell Survival; Cells, Cultured; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Homer Scaffolding Proteins; Hypoxia; Infarction, Middle Cerebral Artery; Neurons; Peptides; Rats; Rats, Sprague-Dawley; Signal Transduction; Spider Venoms; Time Factors; Up-Regulation

Topics: Aldosterone; Amiloride; Animals; Aquaporin 2; Disease Models, Animal; Disease Progression; Epithelial Sodium Channels; Immunohistochemistry; Kidney; Patch-Clamp Techniques; Polycystic Kidney, Autosomal Recessive; Rats; Rats, Sprague-Dawley; Sodium

Topics: Amiloride; Animals; Cell Movement; Disease Models, Animal; Nephrectomy; Podocytes; Proteinuria; Rats; Real-Time Polymerase Chain Reaction; Receptors, Urokinase Plasminogen Activator

Topics: Acid Sensing Ion Channels; Amiloride; Animals; Blotting, Western; Capsaicin; Cnidarian Venoms; Disease Models, Animal; Dose-Response Relationship, Drug; Formaldehyde; Ganglia, Spinal; Hyperalgesia; Pyridines; Rats; Sulfones; Time Factors; TRPV Cation Channels

Topics: Amiloride; Angiotensin II; Animals; Arteries; Blood Pressure; Blood Pressure Determination; Disease Models, Animal; Epithelial Sodium Channels; Female; Hypertension; Kidney; Male; Mice; Mice, Knockout; NG-Nitroarginine Methyl Ester; Proprotein Convertase 9; Proprotein Convertases; Serine Endopeptidases; Sodium; Sodium Chloride, Dietary

Topics: Acid Sensing Ion Channel Blockers; Acid Sensing Ion Channels; Acids; Action Potentials; Amiloride; Animals; Blinking; Cnidarian Venoms; Cornea; Disease Models, Animal; Dry Eye Syndromes; Eye; Guanidines; Guinea Pigs; Hydrogen-Ion Concentration; Male; Nerve Fibers; Ocular Motility Disorders; Ovalbumin; Pain; Patch-Clamp Techniques; Quinazolines; Rats; Rats, Sprague-Dawley; RNA, Messenger; RNA, Small Interfering; Sensory Receptor Cells; Statistics, Nonparametric

Topics: Adaptor Proteins, Signal Transducing; Amiloride; Angiotensin II; Animals; Biomarkers; Blood Pressure; Cell Membrane; Disease Models, Animal; Epithelial Sodium Channel Blockers; Epithelial Sodium Channels; Hypertension; Kidney Tubules, Distal; Mice, Inbred C57BL; Mice, Transgenic; Natriuresis; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Sodium Chloride, Dietary; Time Factors

Topics: Amiloride; Ammonia; Animals; Biological Transport; Blood Pressure; Carbonic Anhydrases; Chlorides; Disease Models, Animal; Enzyme Activation; Epithelial Sodium Channels; Gene Expression Profiling; Gene Regulatory Networks; Gitelman Syndrome; Ketoglutaric Acids; Kidney Glomerulus; Male; Mice; Mice, Knockout; Natriuresis; Nephrons; Paracrine Communication; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Receptors, Notch; Receptors, Purinergic P2; Renal Reabsorption; Signal Transduction; Sodium Chloride; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 3

Topics: Amiloride; Animals; Antihypertensive Agents; Disease Models, Animal; Diuretics; Epithelial Sodium Channels; Hematocrit; Hydrochlorothiazide; Hydrogen-Ion Concentration; Hypertension, Renal; Hypokalemia; Kidney Tubules, Distal; Membrane Potentials; Mice; Mice, Congenic; Mice, Inbred C57BL; Mice, Knockout; Natriuresis; Polymorphism, Single Nucleotide; Potassium; Sodium; Sodium Channel Blockers; Sodium-Bicarbonate Symporters

Topics: Amiloride; Animals; Cell Line, Transformed; Cell Movement; Disease Models, Animal; Gene Expression; Mice; Podocytes; Proteinuria; Receptors, Urokinase Plasminogen Activator

Topics: Amiloride; Animals; Calcium; Cell Proliferation; Disease Models, Animal; Epithelial Sodium Channel Blockers; Epithelial Sodium Channels; Epithelium; Microscopy, Fluorescence; Patch-Clamp Techniques; Polycystic Kidney, Autosomal Recessive; Rats; Rats, Sprague-Dawley; Signal Transduction

Topics: Acute Disease; Amiloride; Animals; Anticonvulsants; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Humans; Male; Mice; Migraine Disorders; Nitroglycerin; Pain Measurement; Propranolol; Serotonin 5-HT1 Receptor Agonists; Species Specificity; Sumatriptan; Treatment Outcome; Valproic Acid; Vasodilator Agents

Topics: Acid Sensing Ion Channel Blockers; Acid Sensing Ion Channels; Amiloride; Animals; Anticonvulsants; Behavior, Animal; Brain; Disease Models, Animal; Down-Regulation; Electroencephalography; Male; Pilocarpine; Rats, Sprague-Dawley; RNA, Messenger; Seizures; Sodium-Hydrogen Exchangers; Time Factors

Topics: Acid Sensing Ion Channels; Amiloride; Animals; Biophysics; Cells, Cultured; Cerebral Cortex; CHO Cells; Cricetinae; Cricetulus; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Embryo, Mammalian; Infarction, Middle Cerebral Artery; Inhibitory Concentration 50; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Models, Molecular; Neurons; Patch-Clamp Techniques; Transfection

Topics: Amides; Amiloride; Animals; Cation Transport Proteins; Cell Hypoxia; Cell Movement; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Enzyme Activation; Hydrogen-Ion Concentration; Hypertension, Pulmonary; Hypoxia; Male; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Protein Kinase Inhibitors; Pulmonary Artery; Pyridines; Rats, Wistar; rho-Associated Kinases; Signal Transduction; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers; Vascular Remodeling

Topics: Acid Sensing Ion Channels; Amiloride; Animals; Blotting, Western; Cyclophosphamide; Disease Models, Animal; Female; Immunohistochemistry; Injections, Intraperitoneal; Mucous Membrane; Rats; Urinary Bladder; Urinary Bladder, Overactive; Urination; Urodynamics

Topics: Amiloride; Animals; beta Catenin; Collagen Type III; Connective Tissue Growth Factor; Cytoprotection; Diabetes Insipidus, Nephrogenic; Disease Models, Animal; Disease Progression; Epithelial Sodium Channel Blockers; Fibrosis; Glycogen Synthase Kinase 3 beta; Kidney; Kidney Diseases; Lithium Carbonate; Male; Myofibroblasts; Rats, Wistar; Transforming Growth Factor beta1

Topics: Allergens; Amiloride; Animals; Aspergillus fumigatus; Asthma; Bronchoalveolar Lavage Fluid; Cell Count; Cells, Cultured; Disease Models, Animal; Epithelial Cells; Epithelial Sodium Channels; Interleukin-13; Lung; Mice, Transgenic; Mucociliary Clearance; Pyroglyphidae; Sodium Channel Blockers; STAT6 Transcription Factor

Topics: Amiloride; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation; Gerbillinae; Glial Fibrillary Acidic Protein; Hippocampus; Integrins; Ischemic Attack, Transient; Pyramidal Cells; Reperfusion; Sodium-Hydrogen Exchangers; Time Factors

Topics: Amiloride; Analysis of Variance; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Pilocarpine; Rats; Rats, Sprague-Dawley; Reaction Time; Seizures; Sodium Channel Blockers

Topics: Amiloride; Animals; Cell Size; Disease Models, Animal; Epithelial Cells; Extracellular Fluid; Hypertension; In Vitro Techniques; Kidney Medulla; Male; NADPH Oxidases; Osmolar Concentration; Oxidative Stress; Rats; Rats, Inbred Dahl; Sodium; Sodium Channel Blockers; Sodium Chloride; Sodium, Dietary; Superoxides; Urothelium

Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Acid Sensing Ion Channels; Acidosis, Lactic; Amiloride; Animals; Antiparkinson Agents; Binding, Competitive; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Male; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Parkinsonian Disorders; Peptides; Radioligand Assay; Sodium Channel Blockers; Sodium Channels; Spider Venoms; Substantia Nigra; Tyrosine 3-Monooxygenase

Topics: Acid Sensing Ion Channels; Adult; Amiloride; Animals; Cells, Cultured; Disease Models, Animal; Female; Humans; Huntington Disease; In Vitro Techniques; Male; Mice; Mice, Transgenic; Middle Aged; Mutation; Nerve Tissue Proteins; Peptides; Rats; Recombinant Fusion Proteins; RNA Interference; Serotonin Plasma Membrane Transport Proteins; Sodium Channel Blockers; Sodium Channels; Solubility

Topics: Amiloride; Animals; Animals, Newborn; Bronchoalveolar Lavage Fluid; Cell Count; Cystic Fibrosis; Disease Models, Animal; DNA; Enzyme-Linked Immunosorbent Assay; Epithelial Sodium Channels; Gene Expression Regulation; Interleukin-13; Lung; Lung Diseases; Mice; Morbidity; Potassium; Sodium; Sodium Channel Blockers; Survival Rate; Treatment Outcome

Topics: Acid Sensing Ion Channels; Amiloride; Amygdala; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Exploratory Behavior; Fever; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Isoquinolines; Male; Membrane Potentials; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Microdialysis; Naphthalenes; Nerve Tissue Proteins; Neurons; Peptides; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Sodium Channels; Spider Venoms; Stress, Psychological

Topics: Amiloride; Analysis of Variance; Animals; Anticonvulsants; Avoidance Learning; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Electroshock; Male; Mice; Motor Activity; Muscle Strength; Psychomotor Performance; Seizures; Sodium Channel Blockers; Time Factors

Topics: Amiloride; Animals; Cystic Fibrosis; Disease Models, Animal; Humans; Mice; Mice, Transgenic; Sodium Channel Blockers; Treatment Outcome

Topics: Amiloride; Animals; Cystic Fibrosis; Disease Models, Animal; Disease Progression; Epithelial Sodium Channel Blockers; Epithelial Sodium Channels; Lung; Mice; Mice, Inbred CFTR; Mice, Transgenic; Sodium; Sodium Channel Blockers

Topics: Albumins; Amiloride; Animals; Blood Pressure; Bronchoalveolar Lavage Fluid; Capillaries; Capillary Permeability; Disease Models, Animal; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Epithelial Sodium Channel Blockers; Epithelial Sodium Channels; Extravascular Lung Water; Hydrostatic Pressure; Male; Oligopeptides; Peptides, Cyclic; Piperidines; Pulmonary Alveoli; Pulmonary Edema; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B; Sodium Channel Blockers; Time Factors; Vasoconstriction

Topics: Acute Lung Injury; Amiloride; Analysis of Variance; Animals; Cells, Cultured; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Epithelial Sodium Channels; Epithelium; Gene Expression Regulation; Male; Neutrophils; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium Channel Blockers; Time Factors; Tumor Necrosis Factor-alpha; Water

Topics: Age Factors; Amiloride; Animals; Chlorides; Cilia; Colforsin; Cystic Fibrosis; Disease Models, Animal; Humans; Ion Transport; Male; Membrane Potentials; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred CFTR; Nasal Cavity; Nasopharynx; Olfactory Mucosa; Respiratory Mucosa; Sodium; Tissue Culture Techniques

Topics: Amiloride; Animals; Arginine Vasopressin; Brain; Brain Edema; Disease Models, Animal; Glucose; Hyponatremia; Injections, Intraventricular; Male; Osmolar Concentration; Potassium; Rats; Rats, Wistar; Sodium; Sodium Channels; Sodium Chloride; Water-Electrolyte Balance

Topics: Amiloride; Animals; Disease Models, Animal; Hypertension; Kidney Tubules; Male; NADPH Oxidases; Nitric Oxide; Oxidative Stress; Probability; Random Allocation; Rats; Rats, Inbred Dahl; Sensitivity and Specificity; Signal Transduction; Sodium Chloride; Sodium-Hydrogen Exchangers; Superoxides

Topics: Amiloride; Animals; Biological Transport; Choroid Plexus; Disease Models, Animal; Epithelial Sodium Channel Blockers; Epithelial Sodium Channels; Hypertension; Male; Ouabain; Rats; Rats, Inbred Dahl; Rats, Wistar; RNA, Messenger; Sodium; Sodium-Potassium-Exchanging ATPase; Sodium, Dietary

Topics: Amiloride; Analysis of Variance; Animals; Arterioles; Disease Models, Animal; Juxtaglomerular Apparatus; Male; Muscle, Smooth, Vascular; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Sodium Channel Blockers; Vasoconstriction; Vasodilation

Topics: Amiloride; Analysis of Variance; Animals; Disease Models, Animal; Edema; Fluorescent Antibody Technique; Gastrointestinal Motility; Hydrostatic Pressure; Intestinal Diseases; Laparotomy; Male; Muscle Contraction; Muscle, Smooth; Polymerase Chain Reaction; Random Allocation; Rats; Reference Values; RNA, Messenger; Sensitivity and Specificity; Signal Transduction; Sodium-Hydrogen Exchangers; STAT3 Transcription Factor

Topics: Acidosis; Adaptation, Physiological; Amiloride; Animals; Animals, Newborn; Bicarbonates; Disease Models, Animal; Gene Expression Regulation; Hydrogen-Ion Concentration; Kidney Tubules, Proximal; Mice; Mice, Inbred C57BL; Microvilli; Rats; RNA, Messenger; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Time Factors

Topics: Amiloride; Animals; Cells, Cultured; Chloride Channels; Chlorides; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Disease Models, Animal; Epithelial Sodium Channels; Hypothyroidism; Ion Transport; Isoproterenol; Swine; Thyroid Gland

Topics: Acid Sensing Ion Channels; Acids; Amiloride; Animals; Behavior, Animal; Biophysics; Calcium; Cells, Cultured; Cricetinae; Cricetulus; Disease Models, Animal; Dithionitrobenzoic Acid; Dose-Response Relationship, Drug; Electric Stimulation; Ganglia, Spinal; Glutamates; Guanidines; Hydrogen-Ion Concentration; Ion Channel Gating; Ligands; Membrane Potentials; Mice; Mice, Knockout; Mutagenesis, Site-Directed; Mutation; Nerve Tissue Proteins; Pain; Pain Measurement; Patch-Clamp Techniques; Protein Structure, Tertiary; Protons; Quinazolines; Rats; Sensory Receptor Cells; Sodium Channels; Sulfhydryl Reagents; Time Factors; Transfection

Topics: Acrolein; Amiloride; Analgesics, Non-Narcotic; Animals; Bradykinin; Camphor; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Flavonoids; Functional Laterality; Hyperalgesia; Male; Mice; Models, Chemical; Pain; Pain Measurement; Pain Threshold; Ruthenium Red

Topics: Amiloride; Animals; Brain Edema; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Disease Progression; Hyponatremia; Injections, Intraventricular; Male; Rats; Rats, Wistar; Sodium Channel Blockers; Sodium Channels; Treatment Outcome

Topics: Amiloride; Animals; Disease Models, Animal; Gait Disorders, Neurologic; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Recovery of Function; Spinal Cord Injuries

Topics: Amiloride; Animals; Cell Movement; Cells, Cultured; Disease Models, Animal; Epithelial Sodium Channels; Glomerulosclerosis, Focal Segmental; In Vitro Techniques; Integrin beta3; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Nephrectomy; Podocytes; Proteinuria; Rats; Receptors, Urokinase Plasminogen Activator; Sodium Channel Blockers; Triamterene

Topics: Amiloride; Angiotensin II Type 1 Receptor Blockers; Animals; Bendroflumethiazide; Disease Models, Animal; Dose-Response Relationship, Drug; Epithelial Sodium Channels; Imidazoles; Male; Natriuresis; Natriuretic Agents; Obesity; Pyridines; Rats; Rats, Zucker; Receptor, Angiotensin, Type 2; Sodium; Sodium Chloride Symporter Inhibitors; Sodium Chloride Symporters; Sulfonamides; Thiophenes; Urination

Topics: Amiloride; Animals; Biomarkers; Calcium; Cells, Cultured; Chlorides; Cyclic AMP; Cystic Fibrosis; Diffusion Chambers, Culture; Disease Models, Animal; Electric Impedance; Epithelial Cells; Exocrine Glands; Humans; Ion Transport; Lactoferrin; Methacholine Chloride; Mucin-5B; Muramidase; Swine; Tight Junctions; Trachea

Topics: Aldosterone; Amiloride; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Biomarkers; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Body Weight; Calcium Channel Blockers; Disease Models, Animal; Dose-Response Relationship, Drug; Homeostasis; Hypertension; Kidney; Losartan; Male; Mice; Mice, Knockout; Natriuresis; Renin; Serine Endopeptidases; Sodium Channel Blockers; Sodium Chloride, Dietary; Telemetry; Time Factors

Topics: Amiloride; Animals; Blood Pressure; Brain; Disease Models, Animal; Endosomal Sorting Complexes Required for Transport; Epithelial Sodium Channels; Female; Heart Rate; Hypertension; Liddle Syndrome; Male; Mice; Mice, Knockout; Nedd4 Ubiquitin Protein Ligases; Sodium; Sodium Chloride, Dietary; Ubiquitin-Protein Ligases

Topics: Acid-Base Equilibrium; Alkalosis; Amiloride; Animals; Animals, Newborn; Asphyxia Neonatorum; Blood-Brain Barrier; Brain; Disease Models, Animal; Humans; Hydrogen-Ion Concentration; Infant, Newborn; Male; Membrane Potentials; Neurons; Rats; Rats, Sprague-Dawley; Seizures; Sodium-Hydrogen Exchangers

Topics: Amiloride; Animals; Aspartic Acid; Asphyxia; Brain; Cell Death; Disease Models, Animal; Hypoxia-Ischemia, Brain; Immunohistochemistry; In Situ Nick-End Labeling; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Microglia; Neuroprotective Agents; Swine

Topics: Acid Sensing Ion Channels; Acids; Amiloride; Amyotrophic Lateral Sclerosis; Animals; Apoptosis; Cells, Cultured; Disease Models, Animal; Humans; Longevity; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Motor Neurons; Mutation; Superoxide Dismutase; Superoxide Dismutase-1

Topics: Age Factors; Amiloride; Animals; Animals, Newborn; Blood Pressure; Cardioplegic Solutions; Coronary Circulation; Creatine Kinase; Disease Models, Animal; Heart Arrest, Induced; Heart Rate; Isotonic Solutions; Myocardial Contraction; Myocardial Reperfusion Injury; Rabbits; Sodium-Hydrogen Exchangers; Time Factors; Ventricular Pressure

Topics: Aldosterone; Amiloride; Animals; Disease Models, Animal; Diuretics; Epithelial Cells; Epithelial Sodium Channels; Hypertension; Kidney; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Models, Biological; Patch-Clamp Techniques; Sodium Channels; Sodium, Dietary

Topics: Amiloride; Analysis of Variance; Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Epilepsy; Kindling, Neurologic; Male; Maze Learning; Memory; Mice; Motor Activity; Pentylenetetrazole; Psychomotor Performance; Reaction Time; Swimming; Time Factors

Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Amiloride; Animals; Biological Transport; Clonidine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Male; Norepinephrine; Octopamine; Ouabain; Phenylephrine; Prazosin; Propranolol; Pulmonary Alveoli; Pulmonary Edema; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase; Up-Regulation; Water-Electrolyte Balance; Yohimbine

Topics: Amiloride; Animals; Disease Models, Animal; High-Frequency Ventilation; Oxygen; Positive-Pressure Respiration; Rabbits; Respiratory Distress Syndrome; Sodium Channel Blockers; Sodium Channels; Time Factors; Up-Regulation

Topics: Acid Sensing Ion Channels; Acids; Amiloride; Animals; Cell Count; Cell Size; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Freund's Adjuvant; Ganglia, Spinal; Hydrogen-Ion Concentration; Hyperalgesia; Isoquinolines; Membrane Potentials; Membrane Proteins; Naphthalenes; Nerve Tissue Proteins; Neurons; Pain Measurement; Pain Threshold; Pain, Postoperative; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Sodium Channels

Topics: Amiloride; Animals; Cells, Cultured; Cilia; Disease Models, Animal; Electrophysiology; Epithelial Cells; Epithelial Sodium Channels; Kidney; Mice; Peptide Hydrolases; Polycystic Kidney, Autosomal Recessive; Sodium; Sodium Channel Blockers; Sodium Channels; Tumor Suppressor Proteins

Topics: Adrenalectomy; Adrenergic beta-Antagonists; Amiloride; Animals; Cardiac Output; Disease Models, Animal; Diuretics; Epinephrine; Extravascular Lung Water; Heart Failure; Immunohistochemistry; Male; Myocardium; Norepinephrine; Organ Size; Propranolol; Pulmonary Alveoli; Pulmonary Edema; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase; Ventricular Pressure

Topics: Amiloride; Animals; Benzolamide; Blood Flow Velocity; Capsaicin; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Disease Models, Animal; Duodenum; Epithelial Cells; Gene Expression; Hydrogen-Ion Concentration; Hyperemia; Intestinal Mucosa; Intracellular Fluid; Laser-Doppler Flowmetry; Male; Methazolamide; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA; Sodium-Calcium Exchanger; TRPV Cation Channels

Topics: Acetophenones; Adenylyl Cyclases; Aging; Aldehydes; Amiloride; Animals; Chlorides; Colforsin; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activators; Mice; Mice, Inbred CFTR; Microscopy, Electron, Scanning; Odorants; Olfactory Mucosa; Olfactory Receptor Neurons; Pentanols; Receptors, Odorant; RNA, Messenger; Smell; Sodium; Sodium Channel Blockers; Time Factors; Tissue Culture Techniques

Topics: Amiloride; Animals; Bronchoconstriction; Cystic Fibrosis; Dinoflagellida; Disease Models, Animal; Ethers; Humans; Ion Transport; Lung; Marine Toxins; Mucociliary Clearance; Oxocins; Polymers; Sheep; Sodium; Sodium Channels; Trichechus

Topics: Amiloride; Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Enzyme Inhibitors; Male; Plasminogen Activator Inhibitor 1; Pulmonary Disease, Chronic Obstructive; Rats; Rats, Wistar; Urokinase-Type Plasminogen Activator

Topics: Amiloride; Amino Acid Motifs; Animals; Butadienes; Cell Line; Disease Models, Animal; Dogs; Down-Regulation; Epidermal Growth Factor; Epithelial Sodium Channel Blockers; Epithelial Sodium Channels; Hypertension; Kidney; Membrane Potentials; Mice; Mice, Transgenic; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mutation; Nitriles; Phosphorylation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Protein Transport; Sodium; Sodium Channel Blockers; Syndrome; Transfection

Topics: Amiloride; Animals; Aquaporin 1; Diabetes Insipidus, Nephrogenic; Disease Models, Animal; Kidney Medulla; Lithium; Lithium Carbonate; Male; Potassium; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium

Topics: Adaptation, Physiological; Amiloride; Animals; Bartter Syndrome; Cation Transport Proteins; Chlorides; Disease Models, Animal; Diuretics; Epithelial Sodium Channels; Female; Furosemide; Glomerular Filtration Rate; Hydrochlorothiazide; Loop of Henle; Male; Mice; Mice, Mutant Strains; Potassium Channels, Inwardly Rectifying; Pregnancy; Sodium; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 1; Up-Regulation

Topics: Amiloride; Amino Acids, Cyclic; Animals; Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Drug Synergism; Homeostasis; Hydrogen-Ion Concentration; Insulin; Insulin Secretion; Insulin-Secreting Cells; Keto Acids; Ketoglutarate Dehydrogenase Complex; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type I; Sodium-Calcium Exchanger

Topics: Acetazolamide; Acidosis, Renal Tubular; Amiloride; Animals; Carbon Dioxide; Chlorides; Disease Models, Animal; Lithium; Lithium Chloride; Maleates; Partial Pressure; Rats

Topics: Acidosis, Renal Tubular; Amiloride; Animals; Carbon Dioxide; Carbonic Anhydrases; Disease Models, Animal; Dogs; Partial Pressure; Pyrazines

Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Amiloride; Biological Transport; Disease Models, Animal; Epithelium; Gallbladder; Gallbladder Neoplasms; Humans; Keratins; Methods; Microscopy, Electron; Mucins; Mucous Membrane; Sodium; Tumor Cells, Cultured

Topics: Amiloride; Animals; Disease Models, Animal; Doxorubicin; Glomerulosclerosis, Focal Segmental; Hypertrophy; Kidney; Male; Molecular Probe Techniques; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium-Hydrogen Exchangers; Sodium, Dietary; Time Factors

Topics: Amiloride; Animals; Cricetinae; Disease Models, Animal; Extravascular Lung Water; Ion Transport; Lung; Male; Mesocricetus; Muscular Dystrophy, Animal; Organ Size; Perfusion; Sodium; Spectrometry, X-Ray Emission; Water-Electrolyte Balance

Topics: Action Potentials; Amiloride; Animals; Calcium-Transporting ATPases; Cell Size; Cells, Cultured; Disease Models, Animal; Guinea Pigs; Heart; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium

Topics: Amiloride; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Cell Death; Combined Modality Therapy; Disease Models, Animal; Flow Cytometry; Hydralazine; Hydrogen-Ion Concentration; Intracellular Fluid; Kinetics; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Nigericin; Sarcoma, Experimental; Sodium-Hydrogen Exchangers; Tumor Cells, Cultured

Topics: Amiloride; Analysis of Variance; Animals; Blood Pressure; Body Weight; Cell Membrane; Disease Models, Animal; Hypertension; Kidney Cortex; Microvilli; Rats; Rats, Inbred Strains; Sodium Chloride, Dietary; Sodium-Hydrogen Exchangers

Topics: Aldosterone; Amiloride; Animals; Cardiomyopathies; Cicatrix; Collagen; Disease Models, Animal; Drug Therapy, Combination; Fibrosis; Hypertension; Hypertrophy; Male; Mineralocorticoids; Myocardium; Necrosis; Rats; Rats, Sprague-Dawley; Time Factors

Topics: Amiloride; Animals; Animals, Newborn; Antigens; Bronchoconstriction; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Histamine; Immunoglobulin E; In Vitro Techniques; Muscle Contraction; Pollen; Rhinitis, Allergic, Seasonal; Sodium; Sodium Channels; Time Factors; Trachea

Topics: Acetylcholine; Amiloride; Animals; Bucladesine; Colitis; Colon; Dinoprostone; Disease Models, Animal; Epithelium; Inflammation; Male; Membrane Potentials; Motor Neurons; Muscle, Smooth; Rabbits; Tetrodotoxin; Trinitrobenzenesulfonic Acid; Vasoactive Intestinal Peptide

Topics: Amiloride; Animals; Creatinine; Disease Models, Animal; Diuretics; Glomerulosclerosis, Focal Segmental; Male; Rats; Rats, Sprague-Dawley; Sodium; Sodium Chloride, Dietary

Topics: Amiloride; Angiotensin II; Animals; Body Weight; Cardiomyopathy, Dilated; Disease Models, Animal; Diuretics; Female; Furosemide; Heart; Mice; Mice, Inbred DBA; Myocardium; Organ Size; Sodium-Hydrogen Exchangers

Topics: Action Potentials; Amiloride; Animals; Arrhythmias, Cardiac; Calcium; Cardiac Pacing, Artificial; Coloring Agents; Disease Models, Animal; Diuretics; Electrocardiography; Eosine Yellowish-(YS); Hematoxylin; Hemodynamics; Hydrogen; Infusions, Intravenous; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Necrosis; Pericardium; Phosphotungstic Acid; Sodium; Swine; Tachycardia, Ventricular; Tetrazolium Salts

Topics: Amiloride; Animals; Animals, Newborn; Disease Models, Animal; Electrophysiology; Epithelial Sodium Channels; Fetal Death; Genes, Recessive; Heterozygote; Humans; Kidney; Lung; Membrane Potentials; Mice; Mice, Knockout; Mice, Transgenic; Mucous Membrane; Pseudohypoaldosteronism; Sodium Channels; Survival Rate

Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Amiloride; Animals; Atenolol; Bronchoalveolar Lavage; Disease Models, Animal; Extracellular Space; Iodine Radioisotopes; Isoproterenol; Male; Mice; Mice, Inbred Strains; Perfusion; Pulmonary Alveoli; Pulmonary Edema; Serum Albumin; Sodium Channel Blockers; Terbutaline

Topics: Adrenal Glands; Adrenalectomy; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Amiloride; Animals; Blood; Blood Pressure; Brain Diseases; Central Nervous System Agents; Cisterna Magna; Disease Models, Animal; Diuretics; Dogs; Epinephrine; Extravascular Lung Water; Female; Hypertension, Pulmonary; Injections; Male; Propanolamines; Proteins; Pulmonary Alveoli; Pulmonary Artery; Pulmonary Edema; Sodium Channel Blockers; Veratrine

Topics: Amiloride; Animals; Biological Transport; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Disease Models, Animal; Epithelial Cells; Humans; Immunity, Innate; Immunohistochemistry; Lung; Mice; Mice, Mutant Strains; Nasal Mucosa; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Pseudomonas Infections; Respiratory System; Sodium

Topics: Amiloride; Animals; Bepridil; Calcium Channel Blockers; Corpus Striatum; Disease Models, Animal; Excitatory Amino Acids; Glucose; Hypoxia, Brain; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Sodium-Calcium Exchanger; Tetrodotoxin

Topics: Acetic Acid; Amiloride; Animals; Animals, Newborn; Behavior, Animal; Capsaicin; Disease Models, Animal; Diuretics; Dose-Response Relationship, Drug; Drug Administration Routes; Formaldehyde; Glutamic Acid; Hot Temperature; Hyperalgesia; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Spinal; Male; Mice; Muscle Contraction; Pain; Pain Measurement; Postural Balance

Topics: Amiloride; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Heart Septum; In Vitro Techniques; Male; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; Perfusion; Rabbits; Sodium-Hydrogen Exchangers

Topics: Amiloride; Animals; Chlorides; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Disease Models, Animal; Diuretics; Epithelial Sodium Channels; Kidney; Kidney Function Tests; Male; Mice; Mice, Inbred CFTR; Mice, Transgenic; Sodium; Sodium Channels; Sodium Chloride, Dietary

Topics: Amiloride; Angina Pectoris; Animals; Azocines; Blood Pressure; Disease Models, Animal; Electrocardiography; Heart; Heart Rate; Isoproterenol; Male; Myocardial Ischemia; Myocardium; Neuroprotective Agents; Pyrroles; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers; Vasopressins

Topics: Amiloride; Animals; Biological Transport, Active; Blotting, Northern; Cholelithiasis; Disease Models, Animal; Electrophysiology; Epithelial Cells; Gallbladder; Guanidines; Immunoblotting; Male; Protein Isoforms; RNA; Sciuridae; Sodium; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Sulfones

Topics: Aerosols; Amiloride; Animals; Cells, Cultured; Cystic Fibrosis; Disease Models, Animal; Diuretics; Goblet Cells; Humans; Ion Transport; Mice; Mice, Inbred C57BL; Microdialysis; Microscopy, Confocal; Mucus; Nasal Mucosa; Osmolar Concentration; Pulmonary Surfactants; Raffinose; Respiratory Mucosa; Sodium Chloride; Uridine Triphosphate

Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Chloride Channels; Chlorides; Colforsin; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Disease Models, Animal; Female; Humans; Ion Transport; Membrane Potentials; Mice; Mice, Inbred Strains; Nasal Mucosa; Thionucleotides

Topics: Amiloride; Animals; Cystic Fibrosis; Disease Models, Animal; Electron Probe Microanalysis; Female; Furosemide; Ion Transport; Liver; Mice; Mice, Inbred Strains; Microscopy, Electron, Scanning

Topics: Acidosis; Amiloride; Animals; Calcium; Cardiotonic Agents; Coronary Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelins; Ferrets; Heart; Hydrogen-Ion Concentration; In Vitro Techniques; Ion Pumps; Myocardial Contraction; Time Factors

Topics: Amiloride; Animals; Biological Transport; Cells, Cultured; Chlorides; Colforsin; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Disease Models, Animal; Epithelium; Intestinal Mucosa; Membrane Proteins; Mice; Mutation; Nasal Mucosa; Trachea

Topics: Amiloride; Animals; Animals, Newborn; Anions; Cystic Fibrosis; Disease Models, Animal; Diuretics; Electron Probe Microanalysis; Embryo, Mammalian; Evaluation Studies as Topic; Female; Furosemide; Metals; Mice; Microscopy, Electron; Pancreas; Submandibular Gland

Topics: Alprostadil; Amiloride; Animals; Cornea; Disease Models, Animal; Neovascularization, Pathologic; Photography; Rabbits

Topics: Acetazolamide; Amiloride; Animals; Biological Transport; Chlorides; Cystic Fibrosis; Disease Models, Animal; Diuretics; Drug Combinations; Female; Furosemide; Male; Mice; Microscopy, Electron; Pancreas; Potassium; Rats; Rats, Inbred Strains; Salivary Glands; Sodium

Topics: Absorption; Administration, Oral; Amiloride; Animals; Bile Acids and Salts; Calcium; Cholesterol; Disease Models, Animal; Evaluation Studies as Topic; Gallstones; Male; Phospholipids; Sciuridae

Topics: Amiloride; Animals; Barium; Biological Transport, Active; Colon; Disease Models, Animal; Electric Conductivity; Intestinal Mucosa; Kidney Failure, Chronic; Male; Potassium; Rats; Rats, Inbred Strains; Reference Values

Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acetylcholine; Amiloride; Animals; Biological Transport; Ceruletide; Chlorides; Colforsin; Cystic Fibrosis; Disease Models, Animal; Furosemide; Kinetics; Male; Pancreas; Rats; Rats, Inbred Strains; Reserpine; Vasoactive Intestinal Peptide

Topics: Amiloride; Animals; Disease Models, Animal; Hyperkalemia; Male; Potassium; Potassium Chloride; Rats; Rats, Inbred Strains

Topics: Adrenalectomy; Amiloride; Animals; Blood Glucose; Chemical Phenomena; Chemistry; Diabetes Mellitus; Disease Models, Animal; Diuretics; Erythrocytes; Furosemide; Glucose Tolerance Test; Hyperkalemia; Insulin; Male; Potassium; Pyrazines; Rats; Sodium; Streptozocin