amiloride has been researched along with Cystic Fibrosis of Pancreas in 241 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 30 (12.45) | 18.7374 |
| 1990's | 116 (48.13) | 18.2507 |
| 2000's | 57 (23.65) | 29.6817 |
| 2010's | 31 (12.86) | 24.3611 |
| 2020's | 7 (2.90) | 2.80 |
| Authors | Studies |
|---|---|
| Astakhova, N; Boucher, RC; Geiss, WB; Hirsh, AJ; Johnson, MR; Molino, BF; Sargent, BJ; Smith, RT; Swenson, BD; Usyatinsky, A; Wyle, MJ; Zamurs, A; Zhang, J | 1 |
| Beazley, S; Burmester, M; Campanucci, VA; Carmalt, JL; Duke, T; Fujiyama, M; Gray, B; Ianowski, JP; Jagadeeshan, S; Le, Y; Luan, X; Machen, TE; Murray, B; Shipley, A; Swekla, K; Tam, JS | 1 |
| Kota, P | 1 |
| Adewale, AT; Åstrand, A; Boitet, E; Edwards, L; Hemmerling, M; Kaza, N; Lever, JEP; Libby, EF; Lindberg, B; Malmgren, A; Root, J; Rowe, SM; Sabater, J; Shei, RJ; Wingren, C | 1 |
| McDonald, VM; Smith, S; Wark, P | 1 |
| Davies, JC; Fajac, I; Henry, T; Jais, JP; Kyrilli, S; Sermet-Gaudelus, I; Wilschanski, M | 1 |
| Levin, MH; Pasricha, ND; Schallhorn, JM; Smith, AJ; Verkman, AS | 1 |
| Eygeris, Y; Henderson, MI; Kim, J; MacDonald, KD; Mukherjee, A; Sahay, G | 1 |
| Abdullah, LH; Ballard, ST; Coakley, RD; Davis, CW; Evans, JR; Ford, AA; Griffith, JD; Kesimer, M; Makhov, AM; Nguyen, K; Wang, TT | 1 |
| Althaus, M | 1 |
| Althaus, M; Schoenberger, M | 1 |
| Liedtke, CM | 1 |
| Bridges, RJ; Krishna Mandava, V; Pilewski, JM; Randell, SH; Rasgado-Flores, H; Siman, H; Van Driessche, W | 1 |
| Ballmann, M; Davies, J; Derichs, N; Gonska, T; Hjelte, L; Leal, T; Melotti, P; Middleton, P; Naehrlich, L; Tümmler, B; van Konigsbruggen-Rietschel, S; Vermeulen, F; Wilschanski, M | 1 |
| Harvey, BJ; Katzenellenbogen, JA; Kim, SH; Saint-Criq, V | 1 |
| Burrows, EF; Noone, PG; Southern, KW | 2 |
| Bangel-Ruland, N; Tomczak, K; Weber, WM | 1 |
| Crampin, E; Sharp, K; Sneyd, J | 1 |
| Capurro, V; Galietta, LJ; Gianotti, A; Moran, O; Scudieri, P; Zegarra-Moran, O | 1 |
| Birket, SE; Chu, KK; Fernandez, CM; Grizzle, WE; Hanes, J; Houser, GH; Lin, V; Liu, L; Mazur, M; Rowe, SM; Shastry, S; Sloane, PA; Solomon, GM; Sorscher, EJ; Tearney, GJ | 1 |
| O'Grady, SM; Panoskaltsis-Mortari, A; Zaidman, NA | 1 |
| Assael, BM; Bergamini, G; Melotti, P; Menin, L; Pintani, E; Tridello, G | 1 |
| George, AM; Iredell, J; Middleton, PG; Treerat, P; Widmer, F | 1 |
| Boucher, RC; Duerr, J; Harm, M; Hirtz, S; Mall, MA; Schatterny, J; Schubert, SC; Treis, D; Zhou, Z | 1 |
| Bush, A; Ratjen, F | 1 |
| Mall, MA | 1 |
| Ratjen, F | 1 |
| Boucher, RC; Grubb, BR; Ostrowski, LE; Rogers, TD | 1 |
| Finkbeiner, WE; Mills, AD; Namkung, W; Padmawar, P; Song, Y; Verkman, AS | 1 |
| Bangel-Ruland, N; Heermann, R; Lindemann, H; Semmler, J; Sobczak, K; Weber, WM | 1 |
| Ball, R; Brownlee, KG; Conway, SP; Denton, M; Duff, AJ; Lee, TW | 1 |
| Bärtsch, P; Dehnert, C; Frese, F; Mairbäurl, H; Schmitt, L; Wiebel, M; Zugck, C | 1 |
| Beckmann, N; Blé, FX; Cannet, C; Collingwood, S; Danahay, H | 1 |
| House, HH; Middleton, PG | 1 |
| Fong, P; Ganta, S; Li, H | 1 |
| De Boeck, K; Feyaerts, N; Proesmans, M; Vermeulen, F | 1 |
| Bauer, R; Grumbach, Y; Lide, E; Lockwood, SR; Rubenstein, RC; Suaud, L | 1 |
| Brose, N; Jiang, C; Kawabe, H; Kimura, T; Lu, C; Lu, WY; Rotin, D; Salter, MW; Xiang, YY; Zhang, W | 1 |
| Derichs, N; Finkbeiner, WE; Jin, BJ; Song, Y; Verkman, AS | 1 |
| Chen, JH; Ernst, S; Itani, OA; Karp, PH; Keshavjee, S; Klesney-Tait, J; Parekh, K; Welsh, MJ; Zabner, J | 1 |
| Angiari, C; Assael, BM; Buffelli, M; Ettorre, M; Johansson, J; Melotti, P; Ricciardi, M; Sorio, C; Verzè, G; Vezzalini, M; Viviani, L | 1 |
| Fong, P; Ganta, S; Li, Y | 1 |
| Borthwell, RM; Finkbeiner, WE; Hajighasemi-Ossareh, M; Lachowicz-Scroggins, ME; Modlin, S; Stevens, JE; Widdicombe, JH | 1 |
| Blouquit-Laye, S; Braun, C; Chinet, T; Dannhoffer, L; Dinh-Xuan, AT; Sage, E | 1 |
| Atherton-Watson, H; Canning, P; Danahay, HL; de Courcey, F; Elborn, JS; Ennis, M; Williams, MT; Zholos, AV | 1 |
| Bronsveld, I; De Boeck, K; de Nooijer, R; Leal, T; Leonard, A; Melotti, P; Middleton, PG; Sands, D; Sermet, I; Vermeulen, F; Wilschanski, M; Yaakov, Y | 1 |
| Coakley, RJ; McElvaney, NG; O'Neill, SJ; Taggart, C | 1 |
| Hirsh, AJ | 1 |
| Boucher, RC; Coakley, RD; Paradiso, AM | 1 |
| Cumps, J; Leal, T; Lebacq, J; Lebecque, P; Wallemacq, P | 1 |
| Ballard, ST; Bowden, AL; Townsley, MI; Trout, L | 1 |
| Chung, NC; Fischer, H; Illek, B; Widdicombe, JH | 1 |
| Boyle, MP; Diener-West, M; Foy, C; Knowles, M; Milgram, L; Standaert, T; Zeitlin, P | 1 |
| Alton, EW; Donohoo, E; Geddes, DM; Middleton, PG; Pollard, KA; Wheatley, JR | 1 |
| Boyle, MP; Guggino, WB; Molina, L; Zeitlin, PL | 1 |
| Abraham, WM; Boucher, RC; Hirsh, AJ; Hopkins, S; Paradiso, AM; Sabater, JR; Smith, RT; Zamurs, A | 1 |
| Galietta, LJ; Pedemonte, N; Qian, L; Salinas, D; Sonawane, ND; Song, Y; Verkman, AS | 1 |
| Jornot, L; Lacroix, JS; Rochat, T | 1 |
| Caldwell, CW; Carter, B; Engelhardt, JF; Gerard, CJ; Godwin, S; Karp, P; Laux, D; Liu, X; Munson, K; Pastor, E; Peluso, R; Shi, H; Thomas, CP; Yan, Z; Zabner, J; Zhang, LN | 1 |
| Duszyk, M; Lam, RS; Shaw, AR | 1 |
| Alton, EW; Davies, MG; Geddes, DM | 1 |
| Kidd, TJ; Middleton, PG; Williams, B | 1 |
| Irokawa, T; Joo, NS; Robbins, RC; Wine, JJ | 1 |
| Kunzelmann, K; McMorran, B; Ousingsawat, J; Scharf, B; Scheidt, K; Schreiber, R; Wainwright, B | 1 |
| Bennett, WD; Boucher, RC; Donaldson, SH; Knowles, MR; Tarran, R; Zeman, KL | 1 |
| Gourgoulianis, K; Hatzoglou, C; Zarogiannis, S | 1 |
| Ballmann, M; Hammer, U; Hubler, A; Mainz, J; Rokahr, C; Zintl, F | 1 |
| Finkbeiner, WE; Levin, MH; Nielson, D; Sullivan, S; Verkman, AS; Yang, B | 1 |
| Corey, M; Dupuis, A; Durie, P; Ellis, L; Jarvi, K; Martin, S; Tsui, LC; Tullis, E; Wilschanski, M; Zielenski, J | 1 |
| Butterworth, MB; Frizzell, RA; Kleyman, TR; McKenna, EE; Myerburg, MM; Peters, KW; Pilewski, JM | 1 |
| Cotton, CU; Davis, PB; Issler, AC; Kelley, TJ; Perez, A; Verkman, AS | 1 |
| Bellon, G; Bui, S; Deneuville, E; Edelman, A; Huet, F; Lenoir, G; Reix, P; Roussel, D; Sermet-Gaudelus, I | 1 |
| Hebestreit, A; Hebestreit, H; Kersting, U | 1 |
| Burns, KA; Grubb, BR; Kulaga, HM; Ostrowski, LE; Reed, RR; Rogers, TD; Wonsetler, RL | 1 |
| Carpenter, S; Corey, M; Durie, P; Ellis, L; O'Brodovich, HM; Smith, D; Sweezey, NB; Tullis, DE | 1 |
| Potera, C | 1 |
| Diggs, PS; Grubb, BR; O'Neal, WK; Ostrowski, LE; Rogers, TD; Yin, W | 1 |
| Becq, F; Bot, AG; De Jonge, HR; Noël, S; Wilke, M | 1 |
| Breslow, JL; Sorscher, EJ | 1 |
| Briggman, JV; Jenkins, MQ; Patton, CJ; Spicer, SS | 1 |
| Boucher, RC; Fischer, N; Gatzy, JT; Knowles, MR; Spock, A; Stutts, MJ | 1 |
| Boucher, R; Gatzy, J; Knowles, M | 2 |
| Dearborn, DG; Hopfer, U; Lebowitz, JL; Taylor, A; Will, PC | 1 |
| Chotai, C; Conn, A; Knox, AJ; Lewis, S; Peckham, DG | 1 |
| Boucher, RC; Knowles, MR; Noone, P; Olivier, K | 1 |
| Boucher, RC; Knowles, MR; Paradiso, AM | 1 |
| Boucher, RC; Canessa, CM; Cohn, JA; Hamrick, M; Olsen, JC; Rossier, BC; Stutts, MJ | 1 |
| Baro-Puigdemasa, I; Danner, I; Escande, D | 1 |
| Devadason, SG; Everard, ML; Le Souef, PN; Sunderland, VB | 1 |
| Smith, AE | 1 |
| Boucher, R; Grubb, B; Knowles, M; Lazarowski, E | 1 |
| Knowles, MR; Noone, PG | 1 |
| Couture, LA; Graham, SM; Gregory, RJ; Smith, AE; Welsh, MJ; Zabner, J | 1 |
| Beaulieu, R; Dessanges, JF; Farinotti, R; Faurisson, F; Grimfeld, A; Kitzis, MD; Lefebvre, JP; Peytavin, G; Sautegeau, A | 1 |
| Boissinot, E; Diot, P; Le Pape, A; Lemarié, E | 1 |
| Colledge, WH; Cuthbert, AW; Evans, MJ; Hickman, ME; MacVinish, LJ; Ratcliff, R | 1 |
| Bennett, WD; Boucher, RC; Hohneker, KW; Knowles, MR; Olivier, KN; Robinson, J | 1 |
| Alton, EW; Geddes, DM; Middleton, PG | 3 |
| Harris, CE; Wilmott, RW | 1 |
| Bernstein, JM; Yankaskas, JR | 1 |
| Fiel, SB | 1 |
| Karp, PH; Smith, JJ; Welsh, MJ | 1 |
| Faller, DP; O'Reilly, CM; Ryan, MP | 1 |
| Fiedler, MA; Wilmott, RW | 1 |
| Finkbeiner, WE; Jiang, C; McCray, PB; Miller, SS; Widdicombe, JH | 1 |
| App, EM; Boucher, RC; Church, N; King, M; Knowles, MR; Ramirez, O; Tomkiewicz, RP; Zayas, JG | 1 |
| Alton, EW; Hodson, ME; Tsang, VT; Yacoub, M | 1 |
| Lindemann, H | 2 |
| Dietzsch, HJ; Wunderlich, P | 1 |
| Smith, JJ; Welsh, MJ | 1 |
| Crawford, O; Dinwiddie, R | 1 |
| Bowler, IM; Conway, SP; James, SL; Kelman, B; Littlewood, JM; Sheldon, TA; Smye, SW; Watson, A; Worthington, D | 1 |
| Greger, R; Kathöfer, S; Kunzelmann, K | 1 |
| Bignamini, E; Viaca, A | 1 |
| Bailey, DL; Bautovich, GJ; Bye, PT; King, M; Regnis, JA; Robinson, M | 1 |
| Bear, CE; Beharry, S; Durie, P; Kent, G; Li, C; Rozmahel, R; Tsui, LC; Wilschanski, MA | 1 |
| Blank, U; Clauss, W; Eistert, B; Fryen, A; Glanz, H; Hüls, G; Lindemann, H; Weber, WM | 1 |
| Bennett, WD; Boucher, RC; Hohneker, KW; Knowles, MR; Olivier, KN; Zeman, KL | 1 |
| Augarten, A; Szeinberg, A; Virgilis, D; Yahav, Y | 1 |
| Beaulieu, R; Dessanges, JF; Farinotti, R; Faurisson, F; Grimfeld, A; Kitzis, MD; Lefevre, JP; Peytavin, G; Sautegeau, A | 1 |
| Barbry, P; Lazdunski, M; Lingueglia, E; Voilley, N | 1 |
| Chinet, T | 1 |
| Allen, RC; Bessou, G; Descamps-Latscha, B; Lenoir, G; Nguyen, AT; Paulais, M; Witko-Sarsat, V | 1 |
| Engelhardt, JF; Wilson, J; Yankaskas, J; Zhang, Y | 1 |
| Ghosal, S; McGaw, J; Taylor, CJ | 1 |
| Eaton, DC; Gomez, LM; Harte, BJ; Kleyman, TR; Lin, C; Ling, BN; McNulty, KA; Smith, PR; Worrell, RT; Zuckerman, JB | 1 |
| Blank, U; Clauss, W; Hofmann, T; Lindemann, H; Münker, G; Rückes, C; Weber, W | 1 |
| Boucher, RC; Grubb, BR | 1 |
| Colledge, WH; Cuthbert, AW; Evans, MJ; Gill, DR; Higgins, CF; Huang, L; Hyde, SC; MacVinish, LJ; Mofford, KA; Ratcliff, R; Sorgi, F | 1 |
| Aubin, G; Clancy, JP; Lesnick, B; McCarty, NA; Ruiz, F; Sorscher, EJ; Venglarik, CJ; Walker, LC; Weatherly, MR | 1 |
| Finkbeiner, WE; Jiang, C; Miller, SS; Widdicombe, JH | 1 |
| Belli, D; Berclaz, PY; Bertrand, D; Duperrex, O; Lacroix, JS; Pochon, N; Rochat, T | 1 |
| Balfour, R; Cheng, SH; Fasbender, A; Launspach, J; Marshall, J; Meeker, D; Morris, JE; Perricone, MA; Smith, AE; Welsh, MJ; Zabner, J | 1 |
| Blank, U; Clauss, W; Lindemann, H; Möller, K; Münker, G; Rieboldt, J; Rückes, C; Weber, WM | 1 |
| Carothers, A; Dorin, JR; Greening, AP; Ho, LP; Innes, JA; Porteous, DJ; Samways, JM | 1 |
| Brouwer, KL; Edwards, L; Knowles, MR; Liu, X; Noone, PG; Regnis, JA; Robinson, M | 1 |
| Cotton, CU; Drumm, ML; Kelley, TJ | 1 |
| Ackerley, C; Bear, CE; Cutz, E; Durie, P; Gyomorey, K; Huan, LJ; Kent, G; Li, C; Ramjeesingh, M; Tanswell, KA; Wang, Y; Wilschanski, M | 1 |
| Boucher, RC; Hofmann, T; Knowles, MR; Lindemann, H; Rückes, C; Stutts, MJ; Weber, WM; Ziersch, A | 1 |
| Cuthbert, AW; Durrington, HJ; Hickman, ME; MacVinish, LJ; Mufti, DA | 1 |
| Anzai, C; Tada, H; Yoshimura, K | 1 |
| Bleich, M; Greger, R; Kunzelmann, K; Mall, M; Schreiber, R | 1 |
| Castellani, C; Delmarco, A; Mastella, G; Pradal, U | 1 |
| Drumm, ML; Kelley, TJ | 1 |
| Loffing, J; McCoy, D; Moyer, BD; Stanton, BA | 1 |
| Boucher, RC; Verghese, MW | 1 |
| Alton, EW; Bush, KA; Chadwick, S; Delaney, SJ; Farley, R; Geddes, DM; Jaffe, A; Middleton, PG; Rolleston, S; Smith, SN; Wainwright, B | 1 |
| Frederiksen, O; Holstein-Rathlou, NH; Larsen, PL; Pedersen, PS; Qvortrup, K | 2 |
| Cuthbert, AW; Hickman, ME; MacVinish, LJ | 1 |
| Kunzelmann, K; Schreiber, R | 1 |
| Bittner, P; Hofmann, T; Hüls, G; Lindemann, H; Schwandt, HJ; Senier, I | 1 |
| Devor, DC; Pilewski, JM | 1 |
| Beck, S; Brandis, M; Greger, R; Kühr, J; Kunzelmann, K; Schütz, VV; Seydewitz, HH | 1 |
| Clauss, W; Lindemann, H; Münker, G; Rückes-Nilges, C; Weber, U; Weber, WM | 1 |
| Grubb, BR | 1 |
| Mrsny, RJ; Shen, BQ; Widdicomb, JH | 1 |
| Duszyk, M; Thethi, K | 1 |
| Boisseau, P; Chailleux, E; Danner, I; Escande, D | 1 |
| Alton, EW; Geddes, DM; Hodson, ME; Jaffe, A; Thomas, SR | 1 |
| Hjelte, L; Jorulf, H; Lagerstrand, L | 1 |
| Knox, AJ; Rodgers, HC | 1 |
| Bridges, RJ; Devor, DC; Gerlach, AC; Gondor, M; Pilewski, JM; Singh, AK | 1 |
| Colledge, WH; Evans, MJ; Ghosal, S; Ratcliff, R; Taylor, CJ | 1 |
| Chaumet-Riffaud, P; d'Athis, P; Foucard, C; Lenoir, G; Marchand, MC; Navarro, J; Pons, G; Sautegeau, A; Sauvage, E | 1 |
| Colledge, WH; Green, R; Kibble, JD; Neal, AM; Taylor, CJ | 1 |
| Brandis, M; Greger, R; Hübner, M; Kuehr, J; Kunzelmann, K; Mall, M; Seydewitz, HH; Wissner, A | 1 |
| Brandis, M; Greger, R; Kuehr, J; Kunzelmann, K; Mall, M; Schreiber, R; Seydewitz, HH; Wissner, A | 1 |
| Gabriel, SE; Hardy, SP; Lethem, MI; Makhlina, M; Thomas, EJ | 1 |
| Brandis, M; Calenborn, D; Gonska, T; Kuehr, J; Kunzelmann, K; Mall, M; Wissner, A | 1 |
| Roomans, GM | 1 |
| Basler, B; Hebestreit, A; Hebestreit, H; Jeschke, R; Kersting, U | 1 |
| Boucher, RC; Davis, CW; Grubb, BR; Hirsh, AJ; Parsons, D; Picher, M; Tarran, R | 1 |
| Barker, PM; Bosworth, DG; Knowles, MR; Legrys, VA; Noone, PG; Southern, KW | 1 |
| Forman, HJ; Fuller, CM; Gao, L; Matalon, S; Sorscher, EJ; Venglarik, CJ; Yankaskas, JR | 1 |
| Cheng, SH; Harris, DJ; Jiang, C; Lane, MB; Lee, ER; Xiao, YF | 1 |
| Brady, KG; Drumm, ML; Kelley, TJ | 1 |
| Ambrose, C; Balamuth, N; Cahill, PA; Canny, S; Caplan, MJ; Cho, E; Egan, ME; Geibel, J; Glöckner-Pagel, J; Pappoe, L; Wagner, CA | 1 |
| Gerritsen, J; Heymans, HS; Hoekstra, MO; Knol, K; van Aalderen, WM | 1 |
| Mörk, AC; Roomans, GM; von Euler, A | 2 |
| Paradiso, AM | 1 |
| Alton, EW; Geddes, DM; Smith, SN | 1 |
| Brown, NE; Clandinin, MT; Kang, JX; Labrecque, PA; Man, SF | 1 |
| Bijman, J; Hoogeveen, AT; Keulemans, JL; Roomans, GM; Sagström, S; Wroblewski, R | 1 |
| Bell, CL; Quinton, PM | 1 |
| Boucher, RC; Johnson, LG; Olsen, JC; Sarkadi, B; Stutts, MJ; Swanstrom, R; Yankaskas, JR | 1 |
| Boucher, RC; Clarke, LL; Gabriel, SE; Grubb, BR; Koller, BH; Smithies, O | 1 |
| Kapranov, NI; Kashirskaia, NIu; Khafizova, ZA; Moin, DM; Petrova, NV; Shabalova, LA; Simonova, OI | 1 |
| Alton, E; Caplen, N; Geddes, D; Williamson, R | 1 |
| Briend, R; Broissand, C; Lenoir, G; Pradier, J; Silly, C; Willemot, JM | 1 |
| Cohn, RC; Putnam, RW; Rudzienski, L | 1 |
| Alton, EW; Barnes, PJ; Geddes, DM; Logan-Sinclair, R; Rogers, DF; Yacoub, M | 1 |
| Boucher, RC; Clarke, LL; Knowles, MR | 2 |
| Brayden, DJ; Cuthbert, AW; Pickles, RJ | 1 |
| Berger, HA; Welsh, MJ | 1 |
| Disser, J; Frömter, E; Hazama, A | 1 |
| Blower, P; Geddes, DM; Graham, A; Nunan, TO; O'Doherty, MJ; Page, CJ; Thomas, SH | 1 |
| Zahaykevich, A | 1 |
| Boucher, RC; Willumsen, NJ | 3 |
| Goldhill, J; Hardcastle, J; Hardcastle, PT; Taylor, CJ | 1 |
| Boucher, RC; Church, NL; Edwards, LJ; Gilligan, P; Helms, RW; King, M; Knowles, MR; Waltner, WE; Yankaskas, JR | 2 |
| Gowen, CW; Gowen, MA; Knowles, MR | 1 |
| Bijman, J; de Jonge, HR; Keulemans, J; Scholte, BJ; Sinaasappel, M; van der Kamp, AW; Verbeek, E | 1 |
| Carmeliet, E; Cassiman, JJ; Jorissen, M; Van den Berghe, H; Vereecke, J | 1 |
| Becker, T; Bittner, P; Boldt, A; Hofmann, T; Lindemann, H; Schwandt, HJ | 1 |
| Brayden, DJ; Cuthbert, AW; Dunne, A; Smyth, RL; Wallwork, J | 1 |
| App, EM; Helfesrieder, R; King, M; Köhler, D; Matthys, H | 1 |
| Marijianowski, M; McMillan, EB; Mulders, H; Roomans, GM; Sagström, S | 1 |
| Quinton, PM | 1 |
| Chesrown, SE; Loughlin, GM; Sauder, RA | 1 |
| Quinton, PM; Reddy, MM | 2 |
| Unal-Maelger, OH; Urbanek, R | 1 |
| Boucher, RC; Jetten, AM; Stutts, MJ; Willumsen, NJ; Yankaskas, JR | 1 |
| Chen, J; Hagiwara, G; Krouse, ME; Lewiston, NJ; Wine, JJ | 1 |
| Boucher, RC; Cheng, EH; Earp, HS; Knowles, MR; Paradiso, AM; Stutts, MJ | 1 |
| Pedersen, PS | 1 |
| Boucher, RC; Davis, CW; Willumsen, NJ | 1 |
| Azizkhan, RG; Berschneider, HM; Boucher, RC; Knowles, MR; Orlando, RC; Powell, DW; Tobey, NA | 1 |
| Boucher, RC; Gatzy, JT; Knowles, MR; Yankaskas, JR | 1 |
| Berschneider, HM; Boucher, RC; Croom, RD; Knowles, MR; Orlando, RC; Powell, DW | 1 |
| Martinez, AM; Martinez, JR | 1 |
| Boucher, RC; Cotton, CU; Gatzy, JT; Knowles, MR; Yankaskas, JR | 1 |
| al-Bazzaz, F; Goldstein, JL; Layden, TJ; Nash, NT; Rao, MC | 1 |
| Aronoff, SC; Cohn, RC; Jacobs, M | 1 |
| App, E; Köhler, D; Matthys, H; Schmitz-Schumann, M; Würtemberger, G | 1 |
| Bijman, J; Quinton, P | 1 |
| Boucher, RC; Cotton, CU; Gatzy, JT; Knowles, MR; Stutts, MJ | 1 |
| Bijman, J; Frömter, E | 1 |
| Boucher, RC; Gatzy, JT; Gingras-Leatherman, J; Gowen, CW; Knowles, MR; Lawson, EE | 1 |
26 review(s) available for amiloride and Cystic Fibrosis of Pancreas
| Article | Year |
|---|---|
Sustained inhibition of ENaC in CF: Potential RNA-based therapies for mutation-agnostic treatment.
Topics: Amiloride; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Sodium Channel Blockers; Epithelial Sodium Channels; Humans; Mutation; RNA | 2022 |
Nebulised hypertonic saline for cystic fibrosis.
Topics: Administration, Inhalation; Adolescent; Adult; Amiloride; Child; Child, Preschool; Cystic Fibrosis; Humans; Infant; Mannitol; Middle Aged; Saline Solution, Hypertonic; Sodium; Xylitol; Young Adult | 2023 |
ENaC inhibitors and airway re-hydration in cystic fibrosis: state of the art.
Topics: Amiloride; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Sodium Channel Blockers; Epithelial Sodium Channels; Humans; Mucociliary Clearance; Protease Inhibitors; Purinergic Agonists; Sodium | 2013 |
Novel small molecule epithelial sodium channel inhibitors as potential therapeutics in cystic fibrosis - a patent evaluation.
Topics: Amiloride; Animals; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Cystic Fibrosis; Epithelial Sodium Channel Blockers; Humans; Lung; Mucociliary Clearance; Patents as Topic; Small Molecule Libraries; Water | 2013 |
Sodium channel blockers for cystic fibrosis.
Topics: Amiloride; Anti-Bacterial Agents; Cystic Fibrosis; Forced Expiratory Volume; Humans; Mucus; Randomized Controlled Trials as Topic; Respiration; Saline Solution, Hypertonic; Sodium Channel Blockers; Vital Capacity | 2014 |
Targeting ENaC as a Molecular Suspect in Cystic Fibrosis.
Topics: Amiloride; Clinical Trials as Topic; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Sodium Channel Blockers; Epithelial Sodium Channels; Humans; Oligonucleotides, Antisense; RNA, Small Interfering; Small Molecule Libraries; Sodium | 2015 |
Sodium channel blockers for cystic fibrosis.
Topics: Amiloride; Cystic Fibrosis; Humans; Mucus; Randomized Controlled Trials as Topic; Respiration; Saline Solution, Hypertonic; Sodium Channel Blockers; Vital Capacity | 2012 |
Altering airway surface liquid volume: inhalation therapy with amiloride and hyperosmotic agents.
Topics: Administration, Inhalation; Amiloride; Cystic Fibrosis; Epithelium; Humans; Mannitol; Mucociliary Clearance; Mucus; Osmotic Pressure; Respiratory System; Saline Solution, Hypertonic; Sodium Channel Blockers | 2002 |
Pharmacologic modulation of salt and water in the airway epithelium in cystic fibrosis.
Topics: Adolescent; Adult; Amiloride; Body Water; Child; Chloride Channels; Clinical Trials as Topic; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelium; Humans; Ion Transport; Lung; Membrane Proteins; Mucociliary Clearance; Sodium Chloride | 1995 |
Treatment of cystic fibrosis based on understanding CFTR.
Topics: Amiloride; Animals; Chloride Channels; Cystic Fibrosis; Molecular Biology; Mutation; Salts | 1995 |
Trends in therapy of abnormal airway epithelial ion and liquid transport.
Topics: Aerosols; Amiloride; Chlorides; Cystic Fibrosis; Humans; Ion Channels; Ion Transport; Sodium; Sodium Channels; Uridine Triphosphate | 1993 |
Pharmacologic treatment of abnormal ion transport in the airway epithelium in cystic fibrosis.
Topics: Adolescent; Adult; Amiloride; Child; Chlorides; Clinical Trials as Topic; Cystic Fibrosis; Epithelium; Humans; Ion Transport; Respiratory System; Sodium | 1995 |
Inhalation-based therapies in the treatment of cystic fibrosis.
Topics: Administration, Inhalation; Aerosols; Amiloride; Cystic Fibrosis; Deoxyribonucleases; Drug Carriers; Humans; Liposomes; Phosphatidylglycerols; Protease Inhibitors; Respiratory Therapy; Tobramycin; Uridine Triphosphate | 1994 |
Clinical management of pulmonary disease in cystic fibrosis.
Topics: Amiloride; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Bronchodilator Agents; Cystic Fibrosis; Expectorants; Humans; Lung Diseases; Lung Transplantation; Respiratory Therapy | 1993 |
Recent advances in the treatment of cystic fibrosis.
Topics: alpha 1-Antitrypsin; Amiloride; Animals; Anti-Bacterial Agents; Chromosomes, Human, Pair 7; Clinical Trials as Topic; Cystic Fibrosis; Deoxyribonuclease I; Genetic Therapy; Humans; Lung Transplantation; Recombinant Proteins; Respiratory Therapy | 1994 |
[Amiloride inhalation therapy in mucoviscidosis].
Topics: Administration, Inhalation; Aerosols; Amiloride; Child; Cystic Fibrosis; Dose-Response Relationship, Drug; Humans | 1993 |
[New aspects of therapy of mucoviscidosis (CF)].
Topics: Adenosine Triphosphate; Administration, Inhalation; Amiloride; Child; Cystic Fibrosis; Deoxyribonucleases; Genetic Therapy; Heart-Lung Transplantation; Humans; Lung Transplantation; Uridine Triphosphate | 1993 |
Recent advances in cystic fibrosis research.
Topics: Adolescent; alpha 1-Antitrypsin; Amiloride; Animals; Child; Child, Preschool; Cystic Fibrosis; Deoxyribonucleases; Genes; Genetic Therapy; Genotype; Humans; Infant; Infant, Newborn; Life Expectancy; Lung; Membrane Proteins; Mice; Prognosis; Research | 1993 |
[New therapeutic modalities for pulmonary disease in cystic fibrosis].
Topics: Amiloride; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Deoxyribonucleases; Humans; Protease Inhibitors; Uridine Triphosphate | 1995 |
Molecular biology of the amiloride-sensitive epithelial Na+ channel.
Topics: Amiloride; Animals; Cystic Fibrosis; DNA, Complementary; Epithelium; Mutagenesis, Site-Directed; Patch-Clamp Techniques; RNA, Messenger; Sodium Channels; src Homology Domains | 1996 |
[Cystic fibrosis].
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Amiloride; Aminoglycosides; Anti-Bacterial Agents; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Diagnosis, Differential; Diuretics; Humans; Mutation; Phosphodiesterase Inhibitors; Prognosis | 1998 |
CFTR, a regulator of channels.
Topics: Amiloride; Animals; Body Water; Calcium; Calcium Channels; Chlorides; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Humans; Hydrogen-Ion Concentration; Intracellular Fluid; Ion Channel Gating; Ion Transport; Membrane Potentials; Potassium; Potassium Channels; Sodium; Sodium Channels; Sulfonylurea Compounds | 1999 |
Pharmacological treatment of the ion transport defect in cystic fibrosis.
Topics: Amiloride; Bicarbonates; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Genistein; Humans; Ion Transport; Phenylbutyrates; Xanthines | 2001 |
[Current advances and present-day issues in mucoviscidosis].
Topics: Adolescent; Amiloride; Anti-Inflammatory Agents; Child; Child, Preschool; Cystic Fibrosis; Female; Heart-Lung Transplantation; Humans; Infant; Lung Transplantation; Male; Pregnancy; Prenatal Diagnosis; Prognosis; Protease Inhibitors | 1992 |
New treatments for cystic fibrosis.
Topics: Amiloride; Anti-Inflammatory Agents; Chlorides; Cystic Fibrosis; Deoxyribonucleases; Genetic Therapy; Humans; Sodium | 1992 |
Amiloride for lung disease in cystic fibrosis.
Topics: Amiloride; Cystic Fibrosis; Humans; Mucociliary Clearance | 1991 |
21 trial(s) available for amiloride and Cystic Fibrosis of Pancreas
| Article | Year |
|---|---|
Can Burkholderia cepacia complex be eradicated with nebulised amiloride and TOBI?
Topics: Adolescent; Amiloride; Anti-Bacterial Agents; Burkholderia cepacia complex; Burkholderia Infections; Child; Cystic Fibrosis; Drug Therapy, Combination; Humans; Nebulizers and Vaporizers; Sodium Channel Blockers; Tobramycin | 2010 |
A multicenter study of the effect of solution temperature on nasal potential difference measurements.
Topics: Adult; Amiloride; Bronchodilator Agents; Chloride Channels; Chlorides; Confidence Intervals; Cystic Fibrosis; Diuretics; Heating; Humans; Ion Transport; Isoproterenol; Middle Aged; Nasal Mucosa | 2003 |
A phase I trial of intranasal Moli1901 for cystic fibrosis.
Topics: Administration, Intranasal; Adolescent; Adult; Amiloride; Biological Transport; Chloride Channels; Cystic Fibrosis; Dose-Response Relationship, Drug; Female; Humans; Isoproterenol; Male; Membrane Potentials; Nasal Mucosa; Peptides, Cyclic; Single-Blind Method | 2004 |
Mucus clearance and lung function in cystic fibrosis with hypertonic saline.
Topics: Administration, Inhalation; Adolescent; Adult; Amiloride; Biological Transport; Cystic Fibrosis; Female; Forced Expiratory Volume; Humans; Male; Maximal Midexpiratory Flow Rate; Mucociliary Clearance; Permeability; Premedication; Saline Solution, Hypertonic; Sodium Channel Blockers; Vital Capacity; Water | 2006 |
Hypertonic saline inhibits luminal sodium channels in respiratory epithelium.
Topics: Adolescent; Adrenergic beta-Agonists; Adult; Amiloride; Case-Control Studies; Cystic Fibrosis; Dose-Response Relationship, Drug; Gluconates; Humans; Isoproterenol; Nasal Mucosa; Saline Solution, Hypertonic; Sodium Channel Blockers; Sodium Channels | 2007 |
Effect of oral digoxin, topical ouabain and salbutamol on transepithelial nasal potential difference in patients with cystic fibrosis.
Topics: Adolescent; Adult; Albuterol; Amiloride; Cystic Fibrosis; Digoxin; Double-Blind Method; Enzyme Inhibitors; Epithelium; Female; Humans; Male; Nasal Mucosa; Ouabain; Pilot Projects; Sodium-Potassium-Exchanging ATPase | 1995 |
Effect of amiloride and saline on nasal mucociliary clearance and potential difference in cystic fibrosis and normal subjects.
Topics: Adolescent; Adult; Amiloride; Cystic Fibrosis; Double-Blind Method; Electrophysiology; Humans; Mucociliary Clearance; Nose; Saccharin; Sodium Chloride | 1993 |
Amiloride inhalation therapy in cystic fibrosis. Influence on ion content, hydration, and rheology of sputum.
Topics: Administration, Inhalation; Adolescent; Adult; Amiloride; Cystic Fibrosis; Double-Blind Method; Electrolytes; Humans; Rheology; Sputum; Time Factors; Water | 1993 |
Nebulised amiloride in respiratory exacerbations of cystic fibrosis: a randomised controlled trial.
Topics: Adolescent; Adult; Aerosols; Amiloride; Child; Cystic Fibrosis; Double-Blind Method; Expectorants; Female; Forced Expiratory Volume; Humans; Male; Prospective Studies; Time Factors; Vital Capacity | 1995 |
Concentration of inhaled amiloride in cystic fibrosis.
Topics: Amiloride; Cystic Fibrosis; Double-Blind Method; Forced Expiratory Volume; Humans; Nebulizers and Vaporizers | 1996 |
Effect of uridine 5'-triphosphate plus amiloride on mucociliary clearance in adult cystic fibrosis.
Topics: Adult; Aerosols; Amiloride; Cystic Fibrosis; Drug Therapy, Combination; Female; Humans; Male; Mucociliary Clearance; Time Factors; Treatment Outcome; Uridine Triphosphate | 1996 |
Comparison of DNA-lipid complexes and DNA alone for gene transfer to cystic fibrosis airway epithelia in vivo.
Topics: Adolescent; Adult; Amiloride; Chlorine; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; DNA; Dose-Response Relationship, Drug; Double-Blind Method; Evaluation Studies as Topic; Female; Gene Transfer Techniques; Genetic Vectors; Humans; Interleukin-6; Lipids; Male; Membrane Potentials; Middle Aged; Nasal Mucosa; Polymerase Chain Reaction; Terbutaline; Time Factors; Treatment Outcome | 1997 |
Aerosolized amiloride: dose effect on nasal bioelectric properties, pharmacokinetics, and effect on sputum expectoration in patients with cystic fibrosis.
Topics: Administration, Intranasal; Adolescent; Adult; Aerosols; Amiloride; Child; Cross-Over Studies; Cystic Fibrosis; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Membrane Potentials; Nasal Mucosa; Sodium; Sodium Channel Blockers; Sputum | 1997 |
Pulmonary gas exchange in cystic fibrosis: basal status and the effect of i.v. antibiotics and inhaled amiloride.
Topics: Administration, Inhalation; Adolescent; Adult; Amiloride; Anti-Bacterial Agents; Blood Flow Velocity; Blood Gas Analysis; Cross-Over Studies; Cystic Fibrosis; Diuretics; Female; Forced Expiratory Volume; Humans; Injections, Intravenous; Lactams; Male; Nebulizers and Vaporizers; Pulmonary Circulation; Single-Blind Method; Spirometry; Tobramycin; Tomography, X-Ray Computed; Treatment Outcome; Ventilation-Perfusion Ratio | 1999 |
The effect of topical benzamil and amiloride on nasal potential difference in cystic fibrosis.
Topics: Administration, Intranasal; Adolescent; Adult; Amiloride; Cross-Over Studies; Cystic Fibrosis; Double-Blind Method; Electric Impedance; Humans; Membrane Potentials; Nasal Mucosa; Retrospective Studies; Sodium Channel Blockers | 1999 |
French multicenter randomized double-blind placebo-controlled trial on nebulized amiloride in cystic fibrosis patients. The Amiloride-AFLM Collaborative Study Group.
Topics: Administration, Inhalation; Adolescent; Adult; Amiloride; Child; Child, Preschool; Cystic Fibrosis; Diuretics; Double-Blind Method; Female; Forced Expiratory Volume; France; Humans; Male; Nebulizers and Vaporizers; Treatment Outcome; Vital Capacity | 2000 |
Pulmonary deposition of nebulised amiloride in cystic fibrosis: comparison of two nebulisers.
Topics: Administration, Inhalation; Adult; Amiloride; Cystic Fibrosis; Female; Humans; Lung; Male; Nebulizers and Vaporizers; Technetium | 1991 |
Aerosolized amiloride as treatment of cystic fibrosis lung disease: a pilot study.
Topics: Administration, Inhalation; Adolescent; Adult; Aerosols; Amiloride; Cystic Fibrosis; Double-Blind Method; Female; Humans; Male; Sputum; Vital Capacity | 1991 |
A pilot study of aerosolized amiloride for the treatment of lung disease in cystic fibrosis.
Topics: Absorption; Adolescent; Adult; Aerosols; Amiloride; Cystic Fibrosis; Double-Blind Method; Female; Humans; Lung Diseases; Male; Mucociliary Clearance; Pilot Projects; Randomized Controlled Trials as Topic; Sodium; Sodium Channels; Vital Capacity | 1990 |
[Elimination of secretions in CF patients under amiloride inhalation].
Topics: Absorption; Administration, Inhalation; Adolescent; Adult; Amiloride; Autogenic Training; Child; Cystic Fibrosis; Female; Humans; Male; Sodium; Sputum | 1990 |
Acute and long-term amiloride inhalation in cystic fibrosis lung disease. A rational approach to cystic fibrosis therapy.
Topics: Administration, Inhalation; Adolescent; Adult; Age Factors; Amiloride; Child; Cough; Cystic Fibrosis; Elasticity; Electrolytes; Female; Humans; Lung Diseases; Male; Mucociliary Clearance; Pneumonia; Random Allocation; Respiratory Function Tests; Sputum; Viscosity | 1990 |
194 other study(ies) available for amiloride and Cystic Fibrosis of Pancreas
| Article | Year |
|---|---|
Design, synthesis, and structure-activity relationships of novel 2-substituted pyrazinoylguanidine epithelial sodium channel blockers: drugs for cystic fibrosis and chronic bronchitis.
Topics: Animals; Bronchi; Bronchitis, Chronic; Combinatorial Chemistry Techniques; Cystic Fibrosis; Dogs; Epithelial Sodium Channels; Guanidines; Models, Molecular; Pyrazines; Respiratory Mucosa; Sodium Channel Blockers; Sodium Channels; Stereoisomerism; Structure-Activity Relationship; Tissue Culture Techniques | 2006 |
cAMP triggers Na
Topics: 1-Methyl-3-isobutylxanthine; Amiloride; Animals; Animals, Genetically Modified; Colforsin; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Disease Models, Animal; Epithelial Sodium Channel Blockers; Epithelial Sodium Channels; Epithelium; Ion Transport; Male; Sodium; Swine | 2021 |
Preclinical evaluation of the epithelial sodium channel inhibitor AZD5634 and implications on human translation.
Topics: Amiloride; Animals; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Sodium Channel Blockers; Epithelial Sodium Channels; Humans; Mucociliary Clearance; Rats; Respiratory Mucosa; Sheep; Sodium Channel Blockers | 2022 |
Insights into the variability of nasal potential difference, a biomarker of CFTR activity.
Topics: Adult; Amiloride; Biological Transport; Bronchodilator Agents; Chlorides; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Sodium Channel Blockers; Female; Humans; Isoproterenol; Male; Membrane Potentials; Mutation; Nasal Mucosa; Observer Variation; Sodium | 2020 |
Ocular Surface Potential Difference Measured in Human Subjects to Study Ocular Surface Ion Transport.
Topics: Amiloride; Cystic Fibrosis; Epithelial Sodium Channels; Eye; Humans; Ion Transport; Ocular Physiological Phenomena; Research Subjects | 2020 |
Engineered mutant α-ENaC subunit mRNA delivered by lipid nanoparticles reduces amiloride currents in cystic fibrosis-based cell and mice models.
Topics: Amiloride; Animals; Cystic Fibrosis; Dehydration; Epithelial Sodium Channels; Humans; Liposomes; Mice; Nanoparticles; RNA, Messenger; Sodium | 2020 |
Defective postsecretory maturation of MUC5B mucin in cystic fibrosis airways.
Topics: Amiloride; Animals; Bronchi; Bumetanide; Cells, Cultured; Cystic Fibrosis; Humans; In Vitro Techniques; Mucin-5B; Swine; Trachea | 2017 |
Understanding the cellular mechanism for inhaled hyperosmotic saline therapy for patients with cystic fibrosis. Focus on "Effect of apical hyperosmotic sodium challenge and amiloride on sodium transport in human bronchial epithelial cells from cystic fibr
Topics: Administration, Inhalation; Amiloride; Bronchi; Cystic Fibrosis; Humans; Ion Transport; Respiratory Mucosa; Saline Solution, Hypertonic; Sodium; Treatment Outcome | 2013 |
Effect of apical hyperosmotic sodium challenge and amiloride on sodium transport in human bronchial epithelial cells from cystic fibrosis donors.
Topics: Amiloride; Bronchi; Cell Culture Techniques; Cells, Cultured; Cystic Fibrosis; Humans; Ion Transport; Osmosis; Respiratory Mucosa; Saline Solution, Hypertonic; Sodium | 2013 |
Nasal potential difference measurements in diagnosis of cystic fibrosis: an international survey.
Topics: Adrenergic beta-Agonists; Amiloride; Chlorides; Cystic Fibrosis; Diagnostic Techniques, Respiratory System; Electrodiagnosis; Epithelial Sodium Channel Blockers; Europe; Health Care Surveys; Humans; Internationality; Isoproterenol; Membrane Potentials; Nasal Mucosa; Observer Variation; Reference Values; Reproducibility of Results; Surveys and Questionnaires | 2014 |
Non-genomic estrogen regulation of ion transport and airway surface liquid dynamics in cystic fibrosis bronchial epithelium.
Topics: Amiloride; Bronchi; Bumetanide; Cell Line; Colforsin; Cyclic AMP; Cystic Fibrosis; Epithelial Cells; Epithelial Sodium Channels; Estradiol; Female; Gene Expression Regulation; Humans; Ion Transport; Male; Ouabain; Protein Kinase C-delta; Respiratory Mucosa; Signal Transduction; Sodium; Sodium-Potassium-Exchanging ATPase; Water | 2013 |
A spatial model of fluid recycling in the airways of the lung.
Topics: Amiloride; Biological Transport; Body Fluids; Computer Simulation; Cystic Fibrosis; Humans; Hydrogen-Ion Concentration; Ion Channels; Ions; Lung; Membrane Potentials; Models, Biological; Reproducibility of Results; Tight Junctions; Time Factors; Water | 2015 |
Pharmacological rescue of mutant CFTR protein improves the viscoelastic properties of CF mucus.
Topics: Amiloride; Aminopyridines; Benzodioxoles; Biological Availability; Cell Culture Techniques; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Sodium Channel Blockers; Humans; Microfluidics; Models, Theoretical; Mucus; Mutant Proteins; Respiratory Mucosa | 2016 |
Combination therapy with cystic fibrosis transmembrane conductance regulator modulators augment the airway functional microanatomy.
Topics: Amiloride; Aminophenols; Animals; Cells, Cultured; Chloride Channel Agonists; Colforsin; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Drug Evaluation, Preclinical; Drug Therapy, Combination; Humans; Membrane Potentials; Mice; Mutation, Missense; NIH 3T3 Cells; Quinolones | 2016 |
Differentiation of human bronchial epithelial cells: role of hydrocortisone in development of ion transport pathways involved in mucociliary clearance.
Topics: Amiloride; Bronchi; Cell Differentiation; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Cells; Epithelial Sodium Channels; Humans; Hydrocortisone; Ion Transport; Mucins; Mucociliary Clearance; Receptors, Adrenergic, beta-2; Respiratory Mucosa; Sodium | 2016 |
Nasal potential difference outcomes support diagnostic decisions in cystic fibrosis.
Topics: Adrenergic beta-Agonists; Adult; Amiloride; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Diagnosis, Differential; Discriminant Analysis; Electric Conductivity; Epithelial Sodium Channel Blockers; Female; Genetic Testing; Humans; Isoproterenol; Male; Membrane Potentials; Mucus; Nasal Mucosa; ROC Curve; Sensitivity and Specificity; Sweat | 2016 |
In vitro interactions of tobramycin with various nonantibiotics against Pseudomonas aeruginosa and Burkholderia cenocepacia.
Topics: Amiloride; Burkholderia cepacia complex; Burkholderia Infections; Cystic Fibrosis; Drug Interactions; Drug Resistance, Bacterial; Drug Therapy, Combination; Humans; Membrane Transport Modulators; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin | 2008 |
Preventive but not late amiloride therapy reduces morbidity and mortality of lung disease in betaENaC-overexpressing mice.
Topics: Amiloride; Animals; Animals, Newborn; Bronchoalveolar Lavage Fluid; Cell Count; Cystic Fibrosis; Disease Models, Animal; DNA; Enzyme-Linked Immunosorbent Assay; Epithelial Sodium Channels; Gene Expression Regulation; Interleukin-13; Lung; Lung Diseases; Mice; Morbidity; Potassium; Sodium; Sodium Channel Blockers; Survival Rate; Treatment Outcome | 2008 |
Amiloride: still a viable treatment option in cystic fibrosis?
Topics: Amiloride; Animals; Cystic Fibrosis; Disease Models, Animal; Humans; Mice; Mice, Transgenic; Sodium Channel Blockers; Treatment Outcome | 2008 |
Role of the amiloride-sensitive epithelial Na+ channel in the pathogenesis and as a therapeutic target for cystic fibrosis lung disease.
Topics: Amiloride; Animals; Cystic Fibrosis; Disease Models, Animal; Disease Progression; Epithelial Sodium Channel Blockers; Epithelial Sodium Channels; Lung; Mice; Mice, Inbred CFTR; Mice, Transgenic; Sodium; Sodium Channel Blockers | 2009 |
Update in cystic fibrosis 2008.
Topics: Amiloride; Animals; Bacterial Infections; Biomarkers; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Deoxycytosine Nucleotides; Disease Progression; Humans; Inflammation; Lung; Oxadiazoles; Respiratory Function Tests; Sodium Channel Blockers; Uridine | 2009 |
Ion transport across CF and normal murine olfactory and ciliated epithelium.
Topics: Age Factors; Amiloride; Animals; Chlorides; Cilia; Colforsin; Cystic Fibrosis; Disease Models, Animal; Humans; Ion Transport; Male; Membrane Potentials; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred CFTR; Nasal Cavity; Nasopharynx; Olfactory Mucosa; Respiratory Mucosa; Sodium; Tissue Culture Techniques | 2009 |
In situ measurement of airway surface liquid [K+] using a ratioable K+-sensitive fluorescent dye.
Topics: Adenosine Triphosphate; Amiloride; Animals; Bronchi; Cells, Cultured; Colforsin; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; DNA Primers; Electrophysiology; Epithelial Cells; Fluorescent Dyes; Humans; Mice; Microscopy, Fluorescence; Potassium; Potassium Channels; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Trachea | 2009 |
[Antisense oligonucleotides for therapy of cystic fibrosis. Inhibition of sodium absorption mediated by ENaC in nasal epithelial cells].
Topics: Amiloride; Blotting, Western; Cells, Cultured; Cystic Fibrosis; Epithelial Sodium Channel Blockers; Humans; Microscopy, Fluorescence; Nasal Mucosa; Oligoribonucleotides, Antisense; Sodium; Sodium Channel Blockers; Transfection | 2009 |
Exercise reduces airway sodium ion reabsorption in cystic fibrosis but not in exercise asthma.
Topics: Adult; Amiloride; Asthma, Exercise-Induced; Chloride Channels; Cystic Fibrosis; Exercise; Exercise Test; Female; Humans; Ion Transport; Isoproterenol; Male; Membrane Potentials; Nose; Sodium; Sodium Channel Blockers; Treatment Outcome; Young Adult | 2011 |
ENaC-mediated effects assessed by MRI in a rat model of hypertonic saline-induced lung hydration.
Topics: Administration, Inhalation; alpha 1-Antitrypsin; Amiloride; Animals; Aprotinin; Body Water; Cystic Fibrosis; Dose-Response Relationship, Drug; Epithelial Sodium Channel Blockers; Epithelial Sodium Channels; Extravascular Lung Water; Fluid Shifts; Guanidines; Lung; Magnetic Resonance Imaging; Male; Mucociliary Clearance; Protease Inhibitors; Pyrazines; Rats; Rats, Inbred BN; Respiratory Mucosa; Saline Solution, Hypertonic; Sodium Channel Blockers; Time Factors | 2010 |
Measurement of airway ion transport assists the diagnosis of cystic fibrosis.
Topics: Adolescent; Adult; Amiloride; Chlorides; Cohort Studies; Cystic Fibrosis; Epithelium; Female; Humans; Ion Transport; Isoproterenol; Male; Membrane Potentials; Nasal Mucosa; Sodium; Young Adult | 2010 |
Altered ion transport by thyroid epithelia from CFTR(-/-) pigs suggests mechanisms for hypothyroidism in cystic fibrosis.
Topics: Amiloride; Animals; Cells, Cultured; Chloride Channels; Chlorides; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Disease Models, Animal; Epithelial Sodium Channels; Hypothyroidism; Ion Transport; Isoproterenol; Swine; Thyroid Gland | 2010 |
Nasal potential measurements on the nasal floor and under the inferior turbinate: does it matter?
Topics: Adolescent; Adult; Amiloride; Child; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Humans; Membrane Potentials; Middle Aged; Mutation; Nasal Mucosa; Sensitivity and Specificity; Turbinates; Young Adult | 2011 |
Regulation of endogenous ENaC functional expression by CFTR and ΔF508-CFTR in airway epithelial cells.
Topics: Aldosterone; Amiloride; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Dexamethasone; Epithelial Sodium Channels; Gene Expression Regulation; Humans; Hydrocortisone; Sequence Deletion; Trypsin | 2011 |
Deletion of the ubiquitin ligase Nedd4L in lung epithelia causes cystic fibrosis-like disease.
Topics: Amiloride; Animals; Animals, Newborn; Cystic Fibrosis; Endosomal Sorting Complexes Required for Transport; Epithelial Sodium Channel Blockers; Epithelial Sodium Channels; Epithelium; Gene Deletion; Lung; Mice; Nedd4 Ubiquitin Protein Ligases; Patch-Clamp Techniques; Ubiquitin-Protein Ligases | 2011 |
Hyperviscous airway periciliary and mucous liquid layers in cystic fibrosis measured by confocal fluorescence photobleaching.
Topics: Amiloride; Bronchi; Cells, Cultured; Cilia; Colforsin; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Dextrans; Epithelial Cells; Epithelial Sodium Channel Blockers; Epithelial Sodium Channels; Fluorescein-5-isothiocyanate; Fluorescence Recovery After Photobleaching; Humans; Microscopy, Confocal; Mucus; Respiratory Mucosa; Viscosity | 2011 |
Human cystic fibrosis airway epithelia have reduced Cl- conductance but not increased Na+ conductance.
Topics: Amiloride; Animals; Anions; Cells, Cultured; Chlorides; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelium; Humans; Ion Transport; Respiratory Mucosa; Sodium; Sodium Channel Blockers; Sodium Channels; Swine | 2011 |
Defective CFTR expression and function are detectable in blood monocytes: development of a new blood test for cystic fibrosis.
Topics: Adolescent; Adult; Aged; Amiloride; Cell Line; Child; Child, Preschool; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Cells; Female; Fluorescence; Hematologic Tests; Heterozygote; Humans; Infant; Male; Membrane Potentials; Middle Aged; Monocytes; Phenotype; Single-Cell Analysis; Young Adult | 2011 |
Endogenous surface expression of ΔF508-CFTR mediates cAMP-stimulated Cl(-) current in CFTR(ΔF508/ΔF508) pig thyroid epithelial cells.
Topics: Amiloride; Animals; Animals, Genetically Modified; Anions; Cells, Cultured; Chloride Channels; Colforsin; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Cells; Gene Knockout Techniques; Ion Transport; Membrane Potentials; Membrane Proteins; Mutation; Protein Folding; Protein Transport; Proteolysis; Sus scrofa; Swine; Temperature; Thyroid Gland | 2012 |
Chloride secretion by cultures of pig tracheal gland cells.
Topics: Amiloride; Animals; Biomarkers; Calcium; Cells, Cultured; Chlorides; Cyclic AMP; Cystic Fibrosis; Diffusion Chambers, Culture; Disease Models, Animal; Electric Impedance; Epithelial Cells; Exocrine Glands; Humans; Ion Transport; Lactoferrin; Methacholine Chloride; Mucin-5B; Muramidase; Swine; Tight Junctions; Trachea | 2012 |
Effect of nitric oxide on epithelial ion transports in noncystic fibrosis and cystic fibrosis human proximal and distal airways.
Topics: Adenosine Triphosphate; Adult; Aged; Amiloride; Bronchi; Chloride Channels; Colforsin; Cyclic GMP; Cyclic N-Oxides; Cystic Fibrosis; Epithelial Sodium Channel Blockers; Epithelial Sodium Channels; Free Radical Scavengers; Guanylate Cyclase; Humans; Imidazoles; Middle Aged; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Oxadiazoles; Purinones; Quinoxalines; Young Adult | 2012 |
Development of primary human nasal epithelial cell cultures for the study of cystic fibrosis pathophysiology.
Topics: Adult; Amiloride; Cells, Cultured; Colforsin; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Sodium Channel Blockers; Female; Humans; Interleukin-1beta; Interleukin-8; Lipopolysaccharides; Male; Nasal Lavage Fluid; Nasal Mucosa; Tumor Necrosis Factor-alpha; Uridine Triphosphate; Young Adult | 2012 |
Influence of perfusate temperature on nasal potential difference.
Topics: Adolescent; Adult; Amiloride; Chloride Channels; Chlorides; Cystic Fibrosis; Healthy Volunteers; Humans; Ion Transport; Ions; Isoproterenol; Middle Aged; Nasal Mucosa; Perfusion; Temperature; Time Factors; Young Adult | 2013 |
Cytosolic pH and the inflammatory microenvironment modulate cell death in human neutrophils after phagocytosis.
Topics: Amiloride; Apoptosis; Body Fluids; Bronchoalveolar Lavage Fluid; Chlorides; Cystic Fibrosis; Cytosol; Epithelium; Escherichia coli; Humans; Hydrogen-Ion Concentration; Inflammation; Ion Transport; Neutrophils; Oxidation-Reduction; Protons; Sodium-Hydrogen Exchangers; Vacuolar Proton-Translocating ATPases; Zinc Compounds | 2002 |
Polarized distribution of HCO3- transport in human normal and cystic fibrosis nasal epithelia.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adult; Amiloride; Barium; Bicarbonates; Biological Transport, Active; Cells, Cultured; Chlorides; Colforsin; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Diffusion Chambers, Culture; Diuretics; Epithelial Cells; Female; Fluoresceins; Fluorometry; Humans; Hydrogen-Ion Concentration; Male; Nasal Mucosa; ortho-Aminobenzoates | 2003 |
Modified method to measure nasal potential difference.
Topics: Adolescent; Adult; Amiloride; Biological Transport, Active; Case-Control Studies; Child; Chlorides; Cohort Studies; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Evoked Potentials; Female; Humans; Ion Transport; Isoproterenol; Male; Middle Aged; Nasal Mucosa; Sodium; Sweat | 2003 |
Disruptive effects of anion secretion inhibitors on airway mucus morphology in isolated perfused pig lung.
Topics: Adrenergic beta-Agonists; Algorithms; Amiloride; Animals; Anions; Bethanechol; Bicarbonates; Bronchi; Bumetanide; Capillary Permeability; Chlorides; Cystic Fibrosis; Diuretics; Exocrine Glands; Isoproterenol; Lung; Microscopy, Electron; Mucins; Mucociliary Clearance; Mucus; Perfusion; Positive-Pressure Respiration; Pulmonary Circulation; Swine; Tissue Fixation | 2003 |
Measurement of nasal potential difference in mild asthmatics.
Topics: Adolescent; Adult; Amiloride; Asthma; Cystic Fibrosis; Female; Humans; Ion Transport; Isoproterenol; Male; Membrane Potentials; Nasal Mucosa; Sodium Chloride | 2003 |
Airway surface liquid calcium modulates chloride permeability in the cystic fibrosis airway.
Topics: Adolescent; Adult; Amiloride; Bronchodilator Agents; Calcium; Calcium Signaling; Cations, Divalent; Chlorides; Cystic Fibrosis; Humans; Isoproterenol; Magnesium; Membrane Potentials; Permeability; Respiratory Mucosa | 2003 |
Evaluation of second generation amiloride analogs as therapy for cystic fibrosis lung disease.
Topics: Absorption; Amiloride; Animals; Bronchi; Cystic Fibrosis; Electrophysiology; Epithelial Cells; Epithelial Sodium Channels; Epithelium; Female; Humans; In Vitro Techniques; Lung Diseases; Mannitol; Microscopy, Confocal; Mucus; Muscle Contraction; Sheep; Sodium; Sodium Channel Blockers; Sodium Channels; Viscosity | 2004 |
Evidence against the rescue of defective DeltaF508-CFTR cellular processing by curcumin in cell culture and mouse models.
Topics: Administration, Oral; Amiloride; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Cycle; Cell Line; Cells, Cultured; Chlorine; Chromatography, High Pressure Liquid; Colforsin; Curcumin; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Cells; Homozygote; Humans; Mice; Mutation; Perfusion; Phenylbutyrates; Rats; Rats, Inbred F344; Temperature; Thyroid Gland; Time Factors; Trachea; Transfection | 2004 |
N-acetylcysteine inhibits Na+ absorption across human nasal epithelial cells.
Topics: Acetylcysteine; Amiloride; Cell Polarity; Cells, Cultured; Chlorides; Cystic Fibrosis; Diffusion Chambers, Culture; Diuretics; Epithelial Sodium Channels; Expectorants; Glutathione; Humans; Membrane Potentials; Nasal Mucosa; Potassium; RNA, Messenger; Sodium; Sodium Channels; Sodium-Potassium-Exchanging ATPase | 2004 |
Dual therapeutic utility of proteasome modulating agents for pharmaco-gene therapy of the cystic fibrosis airway.
Topics: Amiloride; Cell Polarity; Cells, Cultured; CpG Islands; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Dependovirus; DNA Methylation; Doxorubicin; Epithelial Cells; Epithelial Sodium Channels; Genetic Therapy; Genome, Viral; Humans; Promoter Regions, Genetic; Proteasome Endopeptidase Complex; Proteasome Inhibitors; RNA, Messenger; Sodium; Sodium Channels; Time Factors | 2004 |
Membrane cholesterol content modulates activation of BK channels in colonic epithelia.
Topics: Amiloride; Animals; beta-Cyclodextrins; Cell Membrane; Cell Membrane Permeability; Cholesterol; Colon; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelium; Filipin; Membrane Microdomains; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Mutant Strains; Ouabain; Patch-Clamp Techniques; Potassium Channels; Quaternary Ammonium Compounds; Water | 2004 |
The effect of varying tonicity on nasal epithelial ion transport in cystic fibrosis.
Topics: Adult; Amiloride; Case-Control Studies; Culture Techniques; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Cells; Female; Humans; Ion Transport; Isoproterenol; Male; Membrane Potentials; Nasal Mucosa; Reference Values; Sampling Studies; Sensitivity and Specificity | 2005 |
Combination aerosol therapy to treat Burkholderia cepacia complex.
Topics: Administration, Inhalation; Adult; Amiloride; Anti-Bacterial Agents; Burkholderia cepacia complex; Burkholderia Infections; Cystic Fibrosis; Drug Therapy, Combination; Female; Humans; Male; Nebulizers and Vaporizers; Sodium Channel Blockers; Tobramycin | 2005 |
Hyposecretion, not hyperabsorption, is the basic defect of cystic fibrosis airway glands.
Topics: Amiloride; Animals; Chlorides; Colforsin; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; DNA Primers; Exocrine Glands; Humans; Ion Transport; Lung; Polymerase Chain Reaction; Respiratory Mucosa; Swine; Time Factors; Tissue Distribution; Trachea | 2006 |
Flagellin of Pseudomonas aeruginosa inhibits Na+ transport in airway epithelia.
Topics: Adenosine Triphosphate; Amiloride; Animals; Bronchi; Butadienes; Calcium Signaling; Cells, Cultured; Cystic Fibrosis; Egtazic Acid; Epithelial Cells; Epithelial Sodium Channels; Estrenes; Flagellin; G(M1) Ganglioside; Humans; Ion Transport; MAP Kinase Signaling System; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Inbred CFTR; Nitriles; Patch-Clamp Techniques; Phosphatidylinositol 4,5-Diphosphate; Pseudomonas aeruginosa; Pseudomonas Infections; Pyrrolidinones; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Respiratory Tract Infections; Sodium; Sodium Channels; Trachea | 2006 |
Hypertonic saline for cystic fibrosis.
Topics: Administration, Inhalation; Adrenal Cortex Hormones; Amiloride; Aquaporin 3; Cystic Fibrosis; Drug Therapy, Combination; Forced Expiratory Volume; Humans; Mucociliary Clearance; Premedication; Saline Solution, Hypertonic; Sodium Channel Blockers; Up-Regulation | 2006 |
Cystic fibrosis in 65- and 67-year-old siblings. Clinical feature and nasal potential difference measurement in patients with genotypes F508del and 2789+5G-->A.
Topics: Aged; Amiloride; Chlorides; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Genetic Carrier Screening; Genotype; Humans; Male; Membrane Potentials; Nasal Mucosa; Phenotype; Siblings; Sweat | 2006 |
Hypertonic saline therapy in cystic fibrosis: Evidence against the proposed mechanism involving aquaporins.
Topics: Amiloride; Animals; Aquaporins; Cell Membrane; Cystic Fibrosis; Epithelial Cells; Humans; Models, Biological; Perfusion; Permeability; Rats; Rats, Inbred F344; Saline Solution, Hypertonic; Thyroid Gland; Water | 2006 |
Mutations in the cystic fibrosis transmembrane regulator gene and in vivo transepithelial potentials.
Topics: Alleles; Amiloride; Chlorides; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; DNA Mutational Analysis; Epithelial Cells; Genotype; Humans; Male; Nose; Prospective Studies; Sodium Channel Blockers; Sweat; Vas Deferens | 2006 |
Airway surface liquid volume regulates ENaC by altering the serine protease-protease inhibitor balance: a mechanism for sodium hyperabsorption in cystic fibrosis.
Topics: Absorption; Amiloride; Cells, Cultured; Cystic Fibrosis; Epithelial Sodium Channels; Humans; Lung; Serine Endopeptidases; Serine Proteinase Inhibitors; Sodium; Sodium Channels | 2006 |
CFTR inhibition mimics the cystic fibrosis inflammatory profile.
Topics: Amiloride; Cell Differentiation; Cell Nucleus; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Cytokines; Electric Conductivity; Epithelial Cells; Humans; Inflammation; Molecular Mimicry; Mutant Proteins; Protein Transport; rhoA GTP-Binding Protein; Smad3 Protein; Transcription Factor RelA | 2007 |
The CF-CIRC study: a French collaborative study to assess the accuracy of cystic fibrosis diagnosis in neonatal screening.
Topics: Amiloride; Catheterization; Child, Preschool; Chlorides; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Electric Conductivity; Electrodes, Implanted; Equipment Design; Female; France; Genetic Testing; Humans; Infant; Infant, Newborn; Ion Transport; Isoproterenol; Male; Nasal Mucosa; Neonatal Screening; Perfusion; Predictive Value of Tests; Reference Values; Research Design; Sensitivity and Specificity; Sodium; Sodium Channel Blockers; Subcutaneous Tissue; Sweat; Sympathomimetics | 2006 |
Olfactory epithelia exhibit progressive functional and morphological defects in CF mice.
Topics: Acetophenones; Adenylyl Cyclases; Aging; Aldehydes; Amiloride; Animals; Chlorides; Colforsin; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activators; Mice; Mice, Inbred CFTR; Microscopy, Electron, Scanning; Odorants; Olfactory Mucosa; Olfactory Receptor Neurons; Pentanols; Receptors, Odorant; RNA, Messenger; Smell; Sodium; Sodium Channel Blockers; Time Factors; Tissue Culture Techniques | 2007 |
Amiloride-insensitive nasal potential difference varies with the menstrual cycle in cystic fibrosis.
Topics: Adolescent; Adult; Amiloride; Case-Control Studies; Cystic Fibrosis; Estrogens; Female; Follicular Phase; Humans; Ion Transport; Luteal Phase; Membrane Potentials; Menstrual Cycle; Nasal Mucosa; Progesterone; Sex Factors; Sodium Channel Blockers | 2007 |
Marine biology. Florida red tide brews up drug lead for cystic fibrosis.
Topics: Amiloride; Animals; Bronchoconstriction; Cystic Fibrosis; Dinoflagellida; Disease Models, Animal; Ethers; Humans; Ion Transport; Lung; Marine Toxins; Mucociliary Clearance; Oxocins; Polymers; Sheep; Sodium; Sodium Channels; Trichechus | 2007 |
Expression of CFTR from a ciliated cell-specific promoter is ineffective at correcting nasal potential difference in CF mice.
Topics: Amiloride; Animals; Chloride Channels; Cilia; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Cells; Gene Expression; Genetic Therapy; Humans; Immunoprecipitation; Membrane Potentials; Mice; Mice, Knockout; Mice, Transgenic; Nasal Mucosa; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Sodium Channel Blockers; Trachea; Transgenes; Treatment Failure | 2007 |
Parallel improvement of sodium and chloride transport defects by miglustat (n-butyldeoxynojyrimicin) in cystic fibrosis epithelial cells.
Topics: 1-Deoxynojirimycin; Amiloride; Animals; Cell Line; Chlorides; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Cells; Humans; Mice; Mice, Knockout; Nasal Mucosa; Sodium; Sodium Channel Blockers | 2008 |
Cystic fibrosis: a disorder of calcium-stimulated secretion and transepithelial sodium transport?
Topics: Amiloride; Biological Transport, Active; Bronchi; Calcium; Cystic Fibrosis; Epithelium; Humans; Models, Biological; Mucus; Pancreatic Ducts; Salivary Glands; Sodium | 1982 |
Effect of amiloride on potential difference across rectal mucosa in cystic fibrosis patients.
Topics: Adolescent; Adult; Amiloride; Child; Child, Preschool; Cystic Fibrosis; Dose-Response Relationship, Drug; Humans; Infant; Intestinal Mucosa; Ion Channels; Membrane Potentials; Pyrazines; Rectum; Sodium; Water-Electrolyte Balance | 1982 |
Abnormal ion permeation through cystic fibrosis respiratory epithelium.
Topics: Absorption; Amiloride; Chlorides; Cystic Fibrosis; Humans; Ion Channels; Nasal Mucosa; Sodium | 1983 |
Relative ion permeability of normal and cystic fibrosis nasal epithelium.
Topics: Adult; Amiloride; Cell Membrane Permeability; Chlorides; Cystic Fibrosis; Epithelium; Female; Humans; Ions; Male; Membrane Potentials; Nasal Mucosa; Potassium; Sodium | 1983 |
Increased bioelectric potential difference across respiratory epithelia in cystic fibrosis.
Topics: Adolescent; Adult; Age Factors; Amiloride; Bronchi; Child; Child, Preschool; Cystic Fibrosis; Epithelium; Female; Humans; Infant; Male; Membrane Potentials; Middle Aged; Nasal Mucosa; Respiratory System | 1981 |
Saliva from patients with cystic fibrosis inhibits amiloride-sensitive sodium transport.
Topics: Amiloride; Animals; Colon; Cystic Fibrosis; Electrophysiology; In Vitro Techniques; Intestinal Absorption; Male; Pyrazines; Rats; Saliva; Sodium | 1980 |
In vivo nasal potential difference: techniques and protocols for assessing efficacy of gene transfer in cystic fibrosis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amiloride; Biological Transport; Calcium; Child; Child, Preschool; Chlorides; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Electrophysiology; Epithelium; Female; Genetic Therapy; Genotype; Humans; Infant; Intracellular Fluid; Ion Channel Gating; Isoproterenol; Male; Membrane Proteins; Middle Aged; Nasal Mucosa; Nasal Polyps; Perfusion; Potentiometry; Signal Transduction; Sodium | 1995 |
CFTR as a cAMP-dependent regulator of sodium channels.
Topics: 3T3 Cells; Absorption; Amiloride; Animals; Cell Line; Cell Membrane Permeability; Chloride Channels; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; DNA, Complementary; Dogs; Humans; Membrane Proteins; Mice; Patch-Clamp Techniques; Rats; Sodium; Sodium Channels; Transfection | 1995 |
[Pharmacology of ion channels in mucoviscidosis. Physiological bases and therapeutic applications].
Topics: Adenosine Triphosphate; Adolescent; Adult; Amiloride; Child; Child, Preschool; Chloride Channels; Cystic Fibrosis; Epithelium; Female; Genetic Therapy; Humans; Ion Channels; Male; Potassium Channels; Respiratory System; Sodium Channels | 1995 |
An alternative aerosol delivery system for amiloride.
Topics: Aerosols; Amiloride; Cystic Fibrosis; Evaluation Studies as Topic; Nebulizers and Vaporizers | 1995 |
Isobutylmethylxanthine fails to stimulate chloride secretion in cystic fibrosis airway epithelia.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Adult; Amiloride; Bronchi; Cells, Cultured; Chlorides; Colforsin; Cyclic AMP; Cystic Fibrosis; Electric Conductivity; Enzyme Activation; Epithelium; Female; Humans; Male | 1993 |
Adenovirus-mediated gene transfer transiently corrects the chloride transport defect in nasal epithelia of patients with cystic fibrosis.
Topics: Adenoviridae; Adult; Amiloride; Biological Transport; Chlorides; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelium; Female; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Humans; Male; Membrane Potentials; Membrane Proteins; Middle Aged; Nasal Mucosa; Safety; Terbutaline | 1993 |
Nebulizer performance: AFLM study. Association Française de Lutte contre la Mucoviscidose.
Topics: Administration, Inhalation; Aerosols; Amiloride; Colistin; Cystic Fibrosis; Humans; Nebulizers and Vaporizers; Tobramycin | 1995 |
[Characterization by isotope method of the performance of the pneumatic nebulizer NL9 Atomizer in the production of colistin, tobramycin and amiloride aerosols].
Topics: Aerosols; Amiloride; Colistin; Cystic Fibrosis; Evaluation Studies as Topic; Humans; Nebulizers and Vaporizers; Particle Size; Sodium Pertechnetate Tc 99m; Surface Tension; Tobramycin | 1994 |
Ion-transporting activity in the murine colonic epithelium of normal animals and animals with cystic fibrosis.
Topics: Amiloride; Animals; Biological Transport; Carbachol; Colforsin; Colon; Cystic Fibrosis; Epithelium; Furosemide; Ions; Mice; Mice, Inbred CFTR; Potassium; Rubidium Radioisotopes; Tetraethylammonium; Tetraethylammonium Compounds | 1994 |
Protocols for in vivo measurement of the ion transport defects in cystic fibrosis nasal epithelium.
Topics: Adult; Amiloride; Biological Transport, Active; Chlorides; Cystic Fibrosis; Electric Conductivity; Female; Genetic Therapy; Humans; Ion Transport; Isoproterenol; Male; Nasal Mucosa; Perfusion; Sodium; Terbutaline; Time Factors | 1994 |
Increased ion transport in cultured nasal polyp epithelial cells.
Topics: Absorption; Adenosine Triphosphate; Amiloride; Cell Membrane Permeability; Cells, Cultured; Chlorides; Cystic Fibrosis; Humans; Ion Transport; Isoproterenol; Nasal Mucosa; Nasal Polyps; Sodium | 1994 |
Defective fluid transport by cystic fibrosis airway epithelia.
Topics: Amiloride; Biological Transport; Body Water; Cells, Cultured; Cystic Fibrosis; Epithelium; Humans; Respiratory System; Sodium | 1994 |
Amiloride-sensitive sodium uptake into human placental brush border membrane vesicles.
Topics: Amiloride; Biological Transport, Active; Bumetanide; Cystic Fibrosis; Female; Humans; In Vitro Techniques; Ion Transport; Microvilli; Ouabain; Placenta; Pregnancy; Sodium | 1994 |
Altered fluid transport across airway epithelium in cystic fibrosis.
Topics: Absorption; Adenosine Triphosphate; Adolescent; Adult; Amiloride; Body Fluids; Cells, Cultured; Cyclic AMP; Cystic Fibrosis; Epithelial Cells; Epithelium; Female; Humans; Male; Middle Aged; Nasal Mucosa; Sodium; Sodium Channels; Trachea; Uridine Triphosphate | 1993 |
In vitro bioelectric properties of bronchial epithelium from transplanted lungs in recipients with cystic fibrosis.
Topics: Adolescent; Adult; Amiloride; Biopsy; Bronchi; Child; Cystic Fibrosis; Electrophysiology; Epithelium; Female; Heart-Lung Transplantation; Humans; Isoproterenol; Male; Postoperative Period | 1993 |
Fluid and electrolyte transport by cultured human airway epithelia.
Topics: Amiloride; Biological Transport; Body Fluids; Cells, Cultured; Chlorides; Cystic Fibrosis; Electrolytes; Epithelial Cells; Humans; Ion Transport; Nasal Mucosa; Potassium; Sodium; Solutions | 1993 |
Na+ and Cl- conductances in airway epithelial cells: increased Na+ conductance in cystic fibrosis.
Topics: Amiloride; Base Sequence; Cells, Cultured; Chloride Channels; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Diuretics; Epithelial Cells; Epithelium; Humans; Ionophores; Microelectrodes; Molecular Sequence Data; Nasal Mucosa; Nasal Polyps; Nystatin; Patch-Clamp Techniques; Polymerase Chain Reaction; RNA, Messenger; Sodium Channels; Trachea | 1995 |
Effect of hypertonic saline, amiloride, and cough on mucociliary clearance in patients with cystic fibrosis.
Topics: Adolescent; Adult; Aerosols; Amiloride; Analysis of Variance; Confounding Factors, Epidemiologic; Cough; Cystic Fibrosis; Drug Combinations; Expectorants; Female; Forced Expiratory Volume; Humans; Isotonic Solutions; Lung; Male; Mucociliary Clearance; Saline Solution, Hypertonic; Technetium Tc 99m Sulfur Colloid | 1996 |
In vivo measurements of ion transport in long-living CF mice.
Topics: Amiloride; Animals; Chlorides; Crosses, Genetic; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelium; Exons; Female; Homozygote; Intestinal Mucosa; Male; Membrane Potentials; Mice; Mice, Inbred Strains; Mice, Mutant Strains; Nasal Mucosa; Rectum | 1996 |
[Benzamil and mucoviscidosis. Primary culture of nasal mucosa as an electrophysiologic in vitro model].
Topics: Amiloride; Chloride Channels; Culture Techniques; Cystic Fibrosis; Diuretics; Dose-Response Relationship, Drug; Humans; Membrane Potentials; Nasal Mucosa; Sodium; Sodium Channels; Water-Electrolyte Balance | 1996 |
Trimethoprim and tetracycline inhibit airway epithelial sodium absorption.
Topics: Absorption; Adult; Amiloride; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Cystic Fibrosis; Diuretics; Epithelium; Female; Humans; In Vitro Techniques; Ion Transport; Male; Membrane Potentials; Nasal Mucosa; Sheep; Sodium; Tetracycline; Trachea; Trimethoprim | 1996 |
[Comparative study of the performance and ergonomics of nebulizers in cystic fibrosis].
Topics: Administration, Inhalation; Adult; Aerosols; Amiloride; Anti-Bacterial Agents; Child; Colistin; Cystic Fibrosis; Diuretics; Equipment Design; Ergonomics; Humans; Materials Testing; Nebulizers and Vaporizers; Particle Size; Tobramycin | 1996 |
[Pharmacological approach in pulmonary involvement of cystic fibrosis].
Topics: Amiloride; Cystic Fibrosis; Diuretics; Humans; Lung | 1996 |
Disturbed myeloperoxidase-dependent activity of neutrophils in cystic fibrosis homozygotes and heterozygotes, and its correction by amiloride.
Topics: Adolescent; Amiloride; Child; Child, Preschool; Cystic Fibrosis; Female; Heterozygote; Homozygote; Humans; Male; Neutrophils; Peroxidase | 1996 |
In vivo analysis of fluid transport in cystic fibrosis airway epithelia of bronchial xenografts.
Topics: Absorption; Amiloride; Animals; Biological Transport; Body Fluids; Bronchi; Cystic Fibrosis; Electrophysiology; Epithelium; Humans; Male; Rats; Rats, Inbred F344; Reference Values; Sodium; Transplantation, Heterologous | 1996 |
Modification of nasal membrane potential difference with inhaled amiloride and loperamide in the cystic fibrosis (CF) mouse.
Topics: Amiloride; Animals; Cystic Fibrosis; Dose-Response Relationship, Drug; Female; Loperamide; Male; Membrane Potentials; Mice; Nasal Mucosa; Sodium Channel Blockers | 1996 |
Expression of the cystic fibrosis phenotype in a renal amphibian epithelial cell line.
Topics: Amiloride; Animals; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Fluorescent Antibody Technique, Indirect; Gene Expression; Models, Biological; Oligonucleotides, Antisense; Patch-Clamp Techniques; Phenotype; Sodium; Sodium Channel Blockers; Sodium Channels; Xenopus laevis | 1997 |
Cystic fibrosis and non-cystic-fibrosis human nasal epithelium show analogous Na+ absorption and reversible block by phenamil.
Topics: Amiloride; Cells, Cultured; Cystic Fibrosis; Dose-Response Relationship, Drug; Epithelium; Humans; Nasal Mucosa; Sodium | 1997 |
Enhanced colonic Na+ absorption in cystic fibrosis mice versus normal mice.
Topics: Absorption; Aldosterone; Amiloride; Animals; Barium; Colon; Cystic Fibrosis; Electrophysiology; Female; Infusion Pumps; Intestinal Mucosa; Male; Mice; Reference Values; Sodium | 1997 |
Chloride secretion in the trachea of null cystic fibrosis mice: the effects of transfection with pTrial10-CFTR2.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Antioxidants; Avian Sarcoma Viruses; Calcimycin; Chloride Channels; Chlorides; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Diuretics; Genetic Therapy; HeLa Cells; Humans; Hydroquinones; Ionophores; Mice; Mice, Inbred CFTR; Molecular Sequence Data; Plasmids; Promoter Regions, Genetic; Trachea; Transfection | 1997 |
Relationship between airway ion transport and a mild pulmonary disease mutation in CFTR.
Topics: Adolescent; Adrenergic beta-Agonists; Adult; Amiloride; Animals; Child; Chlorides; COS Cells; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Female; Genotype; Humans; Ion Transport; Isoproterenol; Male; Membrane Potentials; Mutation; Nasal Mucosa; Prognosis; Sodium | 1997 |
[Amiloride inhalation].
Topics: Administration, Inhalation; Amiloride; Cystic Fibrosis; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Water-Electrolyte Balance | 1996 |
Fluid transport across cultures of human tracheal glands is altered in cystic fibrosis.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Biological Transport, Active; Body Fluids; Cells, Cultured; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Exocrine Glands; Humans; Ion Transport; Methacholine Chloride; Nitrobenzoates; Thionucleotides; Trachea; Uridine Triphosphate | 1997 |
A new device for in vivo measurement of nasal transepithelial potential difference in cystic fibrosis patients and normal subjects.
Topics: Adult; Amiloride; Case-Control Studies; Cystic Fibrosis; Electric Conductivity; Electrodes; Endoscopy; Equipment Design; Female; Humans; Ion Transport; Male; Nasal Mucosa; Perfusion; Terbutaline; Turbinates | 1997 |
Amiloride-sensitive Na+ channels in human nasal epithelium are different from classical epithelial Na+ channels.
Topics: 1-Methyl-3-isobutylxanthine; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Electrophysiology; Humans; Kinetics; Nasal Mucosa; ortho-Aminobenzoates; Quaternary Ammonium Compounds; Reference Values; Sodium Channels | 1997 |
Correlation between nasal potential difference measurements, genotype and clinical condition in patients with cystic fibrosis.
Topics: Adult; Amiloride; Chlorides; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Female; Forced Expiratory Volume; Genotype; Humans; Isoproterenol; Male; Membrane Potentials; Mutation; Nasal Mucosa | 1997 |
Airway deposition and clearance and systemic pharmacokinetics of amiloride following aerosolization with an ultrasonic nebulizer to normal airways.
Topics: Absorption; Administration, Inhalation; Adult; Aerosols; Amiloride; Bronchi; Bronchoscopy; Chromatography, High Pressure Liquid; Cystic Fibrosis; Diuretics; Dose-Response Relationship, Drug; Humans; Nebulizers and Vaporizers; Regression Analysis; Ultrasonic Therapy | 1997 |
In vivo activation of CFTR-dependent chloride transport in murine airway epithelium by CNP.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chlorides; Colforsin; Cyclic GMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Mice; Mice, Knockout; Mice, Mutant Strains; Models, Biological; Nasal Mucosa; Natriuretic Peptide, C-Type; Nitroprusside; ortho-Aminobenzoates; Proteins; Trachea | 1997 |
Assessment of the efficacy of in vivo CFTR protein replacement therapy in CF mice.
Topics: Amiloride; Animals; Cell Membrane; Cell Membrane Permeability; Chlorides; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Drug Carriers; Drug Delivery Systems; Epithelium; Ion Transport; Liposomes; Membrane Potentials; Mice; Mice, Knockout; Nasal Mucosa; Neutrophils; Phospholipids; Proteolipids | 1998 |
Effects of topically delivered benzamil and amiloride on nasal potential difference in cystic fibrosis.
Topics: Administration, Intranasal; Adolescent; Adult; Aerosols; Amiloride; Cells, Cultured; Cystic Fibrosis; Epithelium; Female; Humans; In Vitro Techniques; Male; Membrane Potentials; Nasal Mucosa; Sodium Channel Blockers; Sodium Channels | 1998 |
Importance of basolateral K+ conductance in maintaining Cl- secretion in murine nasal and colonic epithelia.
Topics: Amiloride; Animals; Benzimidazoles; Calcium; Calcium Channel Agonists; Chlorides; Colforsin; Colon; Cystic Fibrosis; Electric Conductivity; Intestinal Mucosa; Intracellular Membranes; Mice; Nasal Mucosa; Osmolar Concentration; Potassium; Potassium Channel Blockers | 1998 |
The amiloride-inhibitable Na+ conductance is reduced by the cystic fibrosis transmembrane conductance regulator in normal but not in cystic fibrosis airways.
Topics: 1-Methyl-3-isobutylxanthine; Amiloride; Chlorides; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Humans; Nasal Mucosa; Sodium Channels | 1998 |
Nasal potential difference in congenital bilateral absence of the vas deferens.
Topics: Adrenergic beta-Agonists; Adult; Amiloride; Chlorides; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Diuretics; DNA; Epithelium; Female; Follow-Up Studies; Heterozygote; Humans; Ion Transport; Isoproterenol; Male; Membrane Potentials; Mutation; Nasal Mucosa; Sodium; Sweat; Vas Deferens | 1998 |
Inducible nitric oxide synthase expression is reduced in cystic fibrosis murine and human airway epithelial cells.
Topics: Amiloride; Animals; Biological Transport; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Disease Models, Animal; Epithelial Cells; Humans; Immunity, Innate; Immunohistochemistry; Lung; Mice; Mice, Mutant Strains; Nasal Mucosa; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Pseudomonas Infections; Respiratory System; Sodium | 1998 |
Exocytosis is not involved in activation of Cl- secretion via CFTR in Calu-3 airway epithelial cells.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acetazolamide; Amiloride; Cell Membrane; Chloride Channels; Chlorides; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Cells; Exocytosis; Humans; Lung; Microvilli; Nitrobenzoates; ortho-Aminobenzoates; Respiratory System | 1998 |
Effects of ion composition and tonicity on human neutrophil antibacterial activity.
Topics: Adult; Amiloride; Cystic Fibrosis; Humans; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Osmolar Concentration; Peroxidase; Pseudomonas aeruginosa; Respiratory System; Sodium; Staphylococcus aureus; Superoxides; Zinc Sulfate | 1998 |
The in vivo effects of milrinone on the airways of cystic fibrosis mice and human subjects.
Topics: Amiloride; Animals; Chlorides; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelium; Humans; Isoproterenol; Lung; Male; Membrane Potentials; Mice; Milrinone; Mutation; Nose; Phosphodiesterase Inhibitors; Respiratory System; Solutions | 1999 |
Ion transport in epithelial spheroids derived from human airway cells.
Topics: Absorption; Adenosine Triphosphate; Amiloride; Biological Transport; Chlorides; Cyclic AMP; Cystic Fibrosis; Electrophysiology; Epithelium; Female; Humans; Hydrocortisone; Ions; Male; Nasal Polyps; ortho-Aminobenzoates; Sodium; Spheroids, Cellular | 1999 |
Formal analysis of electrogenic sodium, potassium, chloride and bicarbonate transport in mouse colon epithelium.
Topics: Acetazolamide; Amiloride; Animals; Bicarbonates; Biological Transport; Chlorides; Colforsin; Colon; Cystic Fibrosis; Diuretics; Electrophysiology; Epithelium; Furosemide; In Vitro Techniques; Inorganic Chemicals; Membrane Potentials; Mice; Mice, Inbred CFTR; Models, Theoretical; Potassium; Sodium | 1999 |
UTP inhibits Na+ absorption in wild-type and DeltaF508 CFTR-expressing human bronchial epithelia.
Topics: Amiloride; Biological Transport; Bronchi; Bumetanide; Calcium; Cells, Cultured; Chlorides; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Histamine; Homozygote; Humans; Membrane Potentials; Mucous Membrane; Sequence Deletion; Sodium; Tetradecanoylphorbol Acetate; Uridine Triphosphate | 1999 |
Lack of correlation between CFTR expression, CFTR Cl- currents, amiloride-sensitive Na+ conductance, and cystic fibrosis phenotype.
Topics: Amiloride; Cells, Cultured; Chloride Channels; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Cells; Gene Expression; Humans; Nasal Mucosa; Phenotype; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium Channels | 1999 |
Minor role of Cl- secretion in non-cystic fibrosis and cystic fibrosis human nasal epithelium.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphate; Amiloride; Calcium Channel Blockers; Cells, Cultured; Chloride Channels; Chlorides; Cyclic AMP; Cystic Fibrosis; Humans; Membrane Potentials; Nasal Mucosa; Nitrobenzoates; ortho-Aminobenzoates; Reference Values; Sodium; Sodium Channels | 1999 |
Ion transport across the normal and CF neonatal murine intestine.
Topics: Amiloride; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Animals, Newborn; Carbachol; Carrier Proteins; Chlorides; Colforsin; Cystic Fibrosis; Electrochemistry; Electrophysiology; Intestinal Absorption; Intestinal Mucosa; Intestines; Ion Transport; Membrane Glycoproteins; Mice; Mice, Inbred Strains; Monosaccharide Transport Proteins; Reference Values; Sodium; Sodium-Glucose Transporter 1; Symporters | 1999 |
Hepatocyte growth factor inhibits amiloride-sensitive Na(+) channel function in cystic fibrosis airway epithelium in vitro.
Topics: Amiloride; Cell Line; Cystic Fibrosis; Down-Regulation; Epithelial Cells; Hepatocyte Growth Factor; Humans; Protein Kinases; Sodium Channels | 1999 |
Nitric oxide inhibits whole-cell current in cystic fibrosis pancreatic epithelial cells.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Calcium Channel Blockers; Cell Line; Charybdotoxin; Cyclic AMP; Cyclic GMP; Cystic Fibrosis; Diltiazem; Enzyme Inhibitors; Epithelial Cells; Glutathione; Humans; Membrane Potentials; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Oxadiazoles; Pancreas; Patch-Clamp Techniques; Penicillamine; Quinoxalines; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione | 1999 |
Respiratory epithelial ion transport in patients with disseminated bronchiectasis.
Topics: Adolescent; Adult; Amiloride; Bronchiectasis; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Diagnosis, Differential; Epithelium; Female; Genotype; Gluconates; Humans; Ion Transport; Isoproterenol; Male; Membrane Potentials; Middle Aged; Nasal Mucosa; Uridine Triphosphate | 1999 |
Pulmonary disease severity in men with deltaF508 cystic fibrosis and residual chloride secretion.
Topics: Adenosine Triphosphate; Adult; Amiloride; Bronchodilator Agents; Chloride Channels; Chlorides; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Diuretics; Female; Forced Expiratory Volume; Homozygote; Humans; Isoproterenol; Male; Membrane Potentials; Mutation; Retrospective Studies | 1999 |
Fluid absorption related to ion transport in human airway epithelial spheroids.
Topics: Amiloride; Cell Culture Techniques; Cell Membrane; Cells, Cultured; Cystic Fibrosis; Diuretics; Electrophysiology; Epithelial Cells; Female; Humans; Hydrochlorothiazide; Male; Nasal Cavity; Osmosis; Sodium Chloride Symporter Inhibitors; Water; Water-Electrolyte Balance | 1999 |
Stimulation of Cl(-) secretion by chlorzoxazone.
Topics: Amiloride; Anions; Bronchi; Bumetanide; Cell Membrane; Cells, Cultured; Charybdotoxin; Chlorine; Chlorzoxazone; Colforsin; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Drug Interactions; Epithelium; Glyburide; Humans; Isoproterenol; Nasal Mucosa; Nystatin; Potassium Channel Blockers; Rubidium; Zoxazolamine | 2000 |
Sodium channel blockers and uridine triphosphate: effects on nasal potential difference in cystic fibrosis mice.
Topics: Amiloride; Animals; Chlorides; Cystic Fibrosis; Drug Therapy, Combination; Loperamide; Membrane Potentials; Mice; Mice, Inbred CFTR; Nasal Mucosa; Sodium Channels; Uridine Triphosphate | 2000 |
Evidence for cystic fibrosis transmembrane conductance regulator-dependent sodium reabsorption in kidney, using Cftr(tm2cam) mice.
Topics: Amiloride; Animals; Chlorides; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Disease Models, Animal; Diuretics; Epithelial Sodium Channels; Kidney; Kidney Function Tests; Male; Mice; Mice, Inbred CFTR; Mice, Transgenic; Sodium; Sodium Channels; Sodium Chloride, Dietary | 2000 |
Effect of genistein on native epithelial tissue from normal individuals and CF patients and on ion channels expressed in Xenopus oocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adolescent; Adult; Aged; Amiloride; Animals; Child; Child, Preschool; Colforsin; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Dose-Response Relationship, Drug; Epithelium; Female; Gene Expression; Genistein; Humans; Ion Channels; Ion Transport; Membrane Potentials; Middle Aged; Mutation; Nasal Cavity; Oocytes; Rectum; Sodium Channels; Xenopus | 2000 |
Role of K(V)LQT1 in cyclic adenosine monophosphate-mediated Cl(-) secretion in human airway epithelia.
Topics: 1-Methyl-3-isobutylxanthine; Amiloride; Biological Transport; Bronchi; Cell Line, Transformed; Chlorides; Chromans; Colforsin; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Diuretics; Gene Expression; Humans; KCNQ Potassium Channels; KCNQ1 Potassium Channel; Membrane Potentials; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Potassium; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Respiratory Mucosa; Sulfonamides | 2000 |
Expression of nucleotide-regulated Cl(-) currents in CF and normal mouse tracheal epithelial cell lines.
Topics: Amiloride; Animals; Antigens, Viral, Tumor; Cell Line, Transformed; Chloride Channels; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Electrophysiology; Epithelial Cells; Mice; Mice, Knockout; Mice, Transgenic; Nucleotides; Purinergic Agonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Reference Values; Trachea | 2000 |
Inhibition of amiloride-sensitive epithelial Na(+) absorption by extracellular nucleotides in human normal and cystic fibrosis airways.
Topics: Absorption; Adenosine Triphosphate; Adolescent; Adult; Aged; Amiloride; Calcium; Child; Child, Preschool; Cystic Fibrosis; Enzyme Inhibitors; Epithelium; Female; Humans; Indoles; Male; Maleimides; Middle Aged; Nasal Cavity; Nucleotides; Protein Kinase C; Signal Transduction; Sodium; Uridine Triphosphate | 2000 |
Exercise inhibits epithelial sodium channels in patients with cystic fibrosis.
Topics: Adolescent; Adult; Amiloride; Child; Cystic Fibrosis; Diuretics; Epithelium; Exercise; Exercise Test; Female; Humans; Male; Mucus; Respiratory System; Sodium Channels; Water-Electrolyte Balance | 2001 |
The CF salt controversy: in vivo observations and therapeutic approaches.
Topics: Aerosols; Amiloride; Animals; Cells, Cultured; Cystic Fibrosis; Disease Models, Animal; Diuretics; Goblet Cells; Humans; Ion Transport; Mice; Mice, Inbred C57BL; Microdialysis; Microscopy, Confocal; Mucus; Nasal Mucosa; Osmolar Concentration; Pulmonary Surfactants; Raffinose; Respiratory Mucosa; Sodium Chloride; Uridine Triphosphate | 2001 |
A modified technique for measurement of nasal transepithelial potential difference in infants.
Topics: Adult; Amiloride; Cystic Fibrosis; Differential Threshold; Diuretics; Genotype; Humans; Infant; Infant, Newborn; Nasal Mucosa | 2001 |
Chlorzoxazone or 1-EBIO increases Na(+) absorption across cystic fibrosis airway epithelial cells.
Topics: Amiloride; Animals; Benzimidazoles; Calcium Channel Agonists; Cell Polarity; Cells, Cultured; Chlorides; Chlorzoxazone; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Diuretics; Dose-Response Relationship, Drug; Epithelial Cells; Epithelial Sodium Channels; Humans; Ion Transport; Muscle Relaxants, Central; Oocytes; Patch-Clamp Techniques; Potassium; Respiratory Mucosa; Sodium; Sodium Channels; Xenopus laevis | 2001 |
Partial correction of defective Cl(-) secretion in cystic fibrosis epithelial cells by an analog of squalamine.
Topics: Amiloride; Animals; Cells, Cultured; Chlorides; Cholestanols; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Diuretics; Epithelial Cells; Humans; Ion Transport; Ionophores; Membrane Potentials; Mice; Mice, Transgenic; Molecular Structure; Nasal Mucosa; Patch-Clamp Techniques; Recombinant Proteins; Respiratory Mucosa | 2001 |
Examining basal chloride transport using the nasal potential difference response in a murine model.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Chloride Channels; Chlorides; Colforsin; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Disease Models, Animal; Female; Humans; Ion Transport; Membrane Potentials; Mice; Mice, Inbred Strains; Nasal Mucosa; Thionucleotides | 2001 |
Calcium-pump inhibitors induce functional surface expression of Delta F508-CFTR protein in cystic fibrosis epithelial cells.
Topics: Amiloride; Calcium Channel Blockers; Cell Membrane; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Cells; Gene Expression Regulation; Humans; Isoproterenol; Patch-Clamp Techniques; Sequence Deletion; Thapsigargin | 2002 |
[Cystic fibrosis; pathophysiology of electrolyte transport and potential influence of amiloride].
Topics: Amiloride; Biological Transport; Cystic Fibrosis; Electrolytes; Humans; Ion Channels | 1992 |
Effect of chronic treatment with diuretics on mouse liver: a morphological and microanalytical investigation.
Topics: Amiloride; Animals; Cystic Fibrosis; Disease Models, Animal; Electron Probe Microanalysis; Female; Furosemide; Ion Transport; Liver; Mice; Mice, Inbred Strains; Microscopy, Electron, Scanning | 1992 |
Identification of Na(+)-H+ exchange in human normal and cystic fibrotic ciliated airway epithelium.
Topics: Adolescent; Adult; Amiloride; Carrier Proteins; Cells, Cultured; Cilia; Cystic Fibrosis; Epithelium; Female; Humans; Hydrogen-Ion Concentration; Kinetics; Male; Nasal Mucosa; Nasal Polyps; Phorbols; Potassium; Reference Values; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate | 1992 |
Ion transport characteristics of the murine trachea and caecum.
Topics: Amiloride; Animals; Bumetanide; Cecum; Chlorides; Colforsin; Cystic Fibrosis; Electric Conductivity; In Vitro Techniques; Male; Mice; Mice, Transgenic; Phorbol 12,13-Dibutyrate; Pyridazines; Sodium; Trachea | 1992 |
The chloride channel blocker anthracene 9-carboxylate inhibits fatty acid incorporation into phospholipid in cultured human airway epithelial cells.
Topics: Amiloride; Anthracenes; Cells, Cultured; Chloride Channels; Chlorides; Cystic Fibrosis; Electric Conductivity; Epithelium; Fatty Acids; Humans; Kinetics; Linoleic Acid; Linoleic Acids; Membrane Proteins; Nasal Mucosa; Nasal Polyps; Phospholipids; Triglycerides; Verapamil | 1992 |
X-ray micro-analysis of cultured respiratory epithelial cells from patients with cystic fibrosis.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amiloride; Calcimycin; Cells, Cultured; Chlorides; Cyclic AMP; Cystic Fibrosis; Electron Probe Microanalysis; Epithelium; Humans; Ouabain; Potassium; Respiratory System; Sodium | 1992 |
T84 cells: anion selectivity demonstrates expression of Cl- conductance affected in cystic fibrosis.
Topics: Amiloride; Anions; Azides; Bumetanide; Chlorides; Colforsin; Colonic Neoplasms; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Electric Conductivity; Epithelium; Humans; Kinetics; Membrane Potentials; Membrane Proteins; Potassium; Sodium Azide; Tumor Cells, Cultured | 1992 |
Correction of the apical membrane chloride permeability defect in polarized cystic fibrosis airway epithelia following retroviral-mediated gene transfer.
Topics: 3T3 Cells; Amiloride; Animals; Base Sequence; Bronchi; Cell Differentiation; Cell Line; Cell Membrane Permeability; Chloride Channels; Chlorides; Cloning, Molecular; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; DNA, Single-Stranded; Epithelial Cells; Epithelium; Genetic Vectors; Humans; Immunoblotting; Ion Channels; Membrane Proteins; Mice; Molecular Sequence Data; Phenotype; Retroviridae; Trachea; Transduction, Genetic; Transfection | 1992 |
Defective epithelial chloride transport in a gene-targeted mouse model of cystic fibrosis.
Topics: Amiloride; Animals; Biological Transport; Cells, Cultured; Chlorides; Colforsin; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Disease Models, Animal; Epithelium; Intestinal Mucosa; Membrane Proteins; Mice; Mutation; Nasal Mucosa; Trachea | 1992 |
[Amiloride hydrochloride nebulized by oxygen in the treatment of mucoviscidosis].
Topics: Aerosols; Amiloride; Cystic Fibrosis; Humans | 1992 |
In vitro antimicrobial activity of amiloride analogs against Pseudomonas.
Topics: Amiloride; Cystic Fibrosis; Humans; Microbial Sensitivity Tests; Pseudomonas; Species Specificity | 1992 |
Bioelectric properties of cystic fibrosis airways obtained at heart-lung transplantation.
Topics: Amiloride; Bronchi; Cystic Fibrosis; Heart-Lung Transplantation; Humans; Ion Transport; Isoproterenol; Membrane Potentials | 1992 |
Extracellular ATP and UTP induce chloride secretion in nasal epithelia of cystic fibrosis patients and normal subjects in vivo.
Topics: Adenosine; Adenosine Triphosphate; Adolescent; Adult; Amiloride; Cells, Cultured; Chlorides; Cystic Fibrosis; Dose-Response Relationship, Drug; Electrophysiology; Female; Humans; Male; Membrane Potentials; Nasal Mucosa; Uridine Triphosphate | 1992 |
Effects of chronic and in utero treatment with diuretics on mouse exocrine cells studied by X-ray microanalysis.
Topics: Amiloride; Animals; Animals, Newborn; Anions; Cystic Fibrosis; Disease Models, Animal; Diuretics; Electron Probe Microanalysis; Embryo, Mammalian; Evaluation Studies as Topic; Female; Furosemide; Metals; Mice; Microscopy, Electron; Pancreas; Submandibular Gland | 1992 |
Ion transport in cultured epithelia from human sweat glands: comparison of normal and cystic fibrosis tissues.
Topics: Adenylyl Cyclases; Amiloride; Barium; Calcium; Carbachol; Cells, Cultured; Colforsin; Cyclic AMP; Cystic Fibrosis; Epithelium; Humans; Kallidin; Lanthanum; Sodium Channels; Sweat Glands; Terpenes; Thapsigargin | 1991 |
Electrolyte transport in the lungs.
Topics: Amiloride; Chlorides; Cystic Fibrosis; Diuretics; Humans; Ion Channels; Lung; Ouabain; Potassium Channels; Sodium Channels; Sodium-Potassium-Exchanging ATPase | 1991 |
Some properties of sodium and chloride channels in respiratory epithelia of CF- and non-CF-patients.
Topics: Adenosine Triphosphate; Amiloride; Cell Membrane; Chloride Channels; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Electric Conductivity; Epithelium; Humans; In Vitro Techniques; Membrane Proteins; Respiratory System; Sodium Channels | 1991 |
Activation by extracellular nucleotides of chloride secretion in the airway epithelia of patients with cystic fibrosis.
Topics: Adenosine; Adenosine Triphosphate; Adolescent; Adult; Amiloride; Cell Membrane Permeability; Cells, Cultured; Child; Chlorides; Cystic Fibrosis; Epithelium; Female; Humans; Male; Microelectrodes; Middle Aged; Nasal Mucosa; Receptors, Purinergic; Uridine; Uridine Triphosphate | 1991 |
Transcellular sodium transport in cultured cystic fibrosis human nasal epithelium.
Topics: Adolescent; Adult; Amiloride; Amphotericin B; Biological Transport; Bumetanide; Cells, Cultured; Child; Cystic Fibrosis; Electrophysiology; Epithelium; Female; Humans; Male; Nasal Mucosa; Osmolar Concentration; Ouabain; Sodium | 1991 |
Failure of cholinergic stimulation to induce a secretory response from the rectal mucosa in cystic fibrosis.
Topics: Acetylcholine; Amiloride; Animals; Child; Child, Preschool; Cystic Fibrosis; Female; Humans; Infant; Intestinal Mucosa; Membrane Potentials; Rabbits; Rectum | 1991 |
Colonic transepithelial potential difference in infants with cystic fibrosis.
Topics: Amiloride; Chlorides; Cystic Fibrosis; Humans; Infant; Infant, Newborn; Intestinal Absorption; Intestinal Mucosa; Intestinal Obstruction; Meconium; Membrane Potentials; Nasal Mucosa; Rectum; Sweat | 1991 |
Chloride transport in cultured nasal epithelium of cystic fibrosis patients.
Topics: Amiloride; Biological Transport; Cells, Cultured; Chlorides; Cyclic AMP; Cystic Fibrosis; Electrochemistry; Humans; Nasal Mucosa; Nasal Polyps | 1990 |
Non-selective cation and dysfunctional chloride channels in the apical membrane of nasal epithelial cells cultured from cystic fibrosis patients.
Topics: Adolescent; Adult; Amiloride; Biological Transport, Active; Cations; Cell Membrane; Cells, Cultured; Child; Chloride Channels; Cystic Fibrosis; Epithelium; Humans; Membrane Potentials; Membrane Proteins; Nasal Cavity | 1990 |
Altered sensitivity to amiloride in cystic fibrosis. Observations using cultured sweat glands.
Topics: Adolescent; Adult; Amiloride; Child; Culture Techniques; Cystic Fibrosis; Humans; Models, Biological; Sodium; Sweat Glands | 1990 |
Changes in rat and mouse salivary glands and pancreas after chronic treatment with diuretics: a potential animal model for cystic fibrosis.
Topics: Acetazolamide; Amiloride; Animals; Biological Transport; Chlorides; Cystic Fibrosis; Disease Models, Animal; Diuretics; Drug Combinations; Female; Furosemide; Male; Mice; Microscopy, Electron; Pancreas; Potassium; Rats; Rats, Inbred Strains; Salivary Glands; Sodium | 1990 |
Aerosolized amiloride for the treatment of lung disease in cystic fibrosis.
Topics: Aerosols; Amiloride; Cystic Fibrosis; Humans; Lung Diseases | 1990 |
Missing Cl conductance in cystic fibrosis.
Topics: Amiloride; Chlorides; Cystic Fibrosis; Eccrine Glands; Electric Conductivity; Epithelium; Humans; Ion Channels; Membrane Potentials; Sodium; Sweat Glands | 1986 |
Clinical application of transepithelial potential difference measurements in cystic fibrosis.
Topics: Action Potentials; Adolescent; Adult; Amiloride; Child; Cystic Fibrosis; Epithelium; Female; Humans; Ion Channels; Male; Nasal Mucosa | 1987 |
Cl- permeability of sweat duct cell membranes: intracellular microelectrode analysis.
Topics: Amiloride; Cell Membrane Permeability; Chlorides; Cystic Fibrosis; Humans; Ion Channels; Membrane Potentials; Microelectrodes; Sweat Glands | 1987 |
[Status of determining the transepithelial potential difference (PD) of the respiratory epithelium in the diagnosis of mucoviscidosis].
Topics: Adolescent; Adult; Amiloride; Child; Child, Preschool; Chlorides; Cystic Fibrosis; Epithelium; Female; Genetic Carrier Screening; Humans; Infant; Ion Channels; Male; Membrane Potentials; Middle Aged; Nasal Mucosa; Sodium | 1988 |
Activation of an apical Cl- conductance by Ca2+ ionophores in cystic fibrosis airway epithelia.
Topics: Adolescent; Adult; Amiloride; Calcimycin; Calcium; Cells, Cultured; Chloride Channels; Chlorides; Cystic Fibrosis; Electric Conductivity; Ethers; Female; Humans; Ion Channels; Ionomycin; Isoproterenol; Male; Membrane Potentials; Membrane Proteins; Nasal Polyps; Reference Values; Turbinates | 1989 |
Persistence of abnormal chloride conductance regulation in transformed cystic fibrosis epithelia.
Topics: Amiloride; Antigens, Polyomavirus Transforming; Calcimycin; Cell Line; Cell Membrane; Chloride Channels; Chlorides; Colforsin; Cystic Fibrosis; Electric Conductivity; Epithelium; Ethers; Freeze Fracturing; Humans; Intercellular Junctions; Ion Channels; Ionomycin; Membrane Proteins; Microscopy, Electron; Nasal Polyps; Simian virus 40; Transformation, Genetic | 1989 |
Ion channels in normal human and cystic fibrosis sweat gland cells.
Topics: Adolescent; Adult; Aged; Amiloride; Anions; Calcium; Cations; Cell Membrane; Cells, Cultured; Chloride Channels; Chlorides; Cystic Fibrosis; Electric Conductivity; Epithelium; Fibroblasts; Humans; Ion Channels; Membrane Proteins; Middle Aged; Potassium Channels; Sweat Glands | 1989 |
Localization of Cl- conductance in normal and Cl- impermeability in cystic fibrosis sweat duct epithelium.
Topics: Amiloride; Cell Membrane Permeability; Chloride Channels; Chlorides; Cystic Fibrosis; Epithelium; Humans; In Vitro Techniques; Ion Channels; Kinetics; Membrane Potentials; Membrane Proteins; Reference Values; Sweat Glands | 1989 |
Chloride secretory response of cystic fibrosis human airway epithelia. Preservation of calcium but not protein kinase C- and A-dependent mechanisms.
Topics: 1-Methyl-3-isobutylxanthine; Adolescent; Adult; Amiloride; Bradykinin; Calcimycin; Calcium; Child; Chlorides; Cyclic AMP; Cystic Fibrosis; Electric Conductivity; Epithelium; Female; Humans; Isoproterenol; Male; Nasal Mucosa; Protein Kinase C; Tetradecanoylphorbol Acetate | 1989 |
Human sweat duct cells in primary culture. Basic bioelectric properties of cultures derived from normals and patients with cystic fibrosis.
Topics: Adolescent; Adult; Amiloride; Cells, Cultured; Child; Child, Preschool; Culture Media; Cystic Fibrosis; Electric Conductivity; Epithelial Cells; Humans; Membrane Potentials; Potassium Channels; Sodium Channels; Sweat Glands; Temperature | 1989 |
Cellular Cl- transport in cultured cystic fibrosis airway epithelium.
Topics: Adolescent; Adult; Amiloride; Biological Transport; Bumetanide; Cells, Cultured; Child; Child, Preschool; Chlorides; Cystic Fibrosis; Epithelium; Female; Humans; Male; Nasal Mucosa; Potassium | 1989 |
Shunt resistance and ion permeabilities in normal and cystic fibrosis airway epithelia.
Topics: Amiloride; Cell Membrane Permeability; Chlorides; Cystic Fibrosis; Electrolytes; Epithelium; Humans; Nasal Mucosa; Sodium | 1989 |
Altered intestinal chloride transport in cystic fibrosis.
Topics: Adult; Amiloride; Biological Transport; Calcimycin; Chlorides; Cyclic AMP; Cystic Fibrosis; Electric Conductivity; Female; Glucose; Humans; Infant; Infant, Newborn; Intestinal Absorption; Intestinal Mucosa; Intestines; Male; Membrane Potentials; Sodium; Theophylline | 1988 |
Persistence of abnormal chloride ion permeability in cystic fibrosis nasal epithelial cells in heterologous culture.
Topics: Adolescent; Adult; Aged; Amiloride; Animals; Cell Membrane Permeability; Cells, Cultured; Child; Chlorides; Cystic Fibrosis; Epithelium; Female; Humans; Isoproterenol; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Nude; Middle Aged; Nasal Mucosa; Rabbits; Trachea | 1985 |
Colonic and esophageal transepithelial potential difference in cystic fibrosis.
Topics: Adult; Aged; Amiloride; Colon; Cystic Fibrosis; Epithelium; Esophagus; Female; Humans; In Vitro Techniques; Intestinal Mucosa; Male; Membrane Potentials | 1989 |
The reserpine-treated rat as an experimental animal model for cystic fibrosis: abnormal Cl transport in pancreatic acinar cells.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acetylcholine; Amiloride; Animals; Biological Transport; Ceruletide; Chlorides; Colforsin; Cystic Fibrosis; Disease Models, Animal; Furosemide; Kinetics; Male; Pancreas; Rats; Rats, Inbred Strains; Reserpine; Vasoactive Intestinal Peptide | 1988 |
Evidence for reduced Cl- and increased Na+ permeability in cystic fibrosis human primary cell cultures.
Topics: Adolescent; Adult; Amiloride; Biological Transport, Active; Cell Membrane Permeability; Cells, Cultured; Child; Chlorides; Cystic Fibrosis; Epithelium; Humans; Isoproterenol; Membrane Potentials; Nasal Mucosa; Sodium | 1988 |
Rectum has abnormal ion transport but normal cAMP-binding proteins in cystic fibrosis.
Topics: Adult; Amiloride; Biological Transport, Active; Carrier Proteins; Chlorides; Cyclic AMP Receptor Protein; Cystic Fibrosis; Female; Humans; Ions; Male; Molecular Weight; Permeability; Rectum; Theophylline | 1988 |
In vitro activity of amiloride combined with tobramycin against Pseudomonas isolates from patients with cystic fibrosis.
Topics: Amiloride; Child; Cystic Fibrosis; Humans; Microbial Sensitivity Tests; Pseudomonas; Pseudomonas Infections; Tobramycin | 1988 |
Inhalation of amiloride improves the mucociliary and the cough clearance in patients with cystic fibroses.
Topics: Adolescent; Adult; Amiloride; Bronchi; Child; Cilia; Cough; Cystic Fibrosis; Female; Humans; Male; Metabolic Clearance Rate; Mucus | 1986 |
Permeability properties of cell membranes and tight junctions of normal and cystic fibrosis sweat ducts.
Topics: Amiloride; Cell Membrane Permeability; Chlorides; Cystic Fibrosis; Humans; Intercellular Junctions; Ouabain; Potassium; Sodium; Sweat Glands | 1987 |
Abnormal apical cell membrane in cystic fibrosis respiratory epithelium. An in vitro electrophysiologic analysis.
Topics: Amiloride; Cell Membrane; Cell Membrane Permeability; Chlorides; Cystic Fibrosis; Epithelium; Humans; In Vitro Techniques; Isoproterenol; Membrane Potentials; Nasal Mucosa | 1987 |
Direct demonstration of high transepithelial chloride-conductance in normal human sweat duct which is absent in cystic fibrosis.
Topics: Adult; Amiloride; Cell Membrane Permeability; Chlorides; Cystic Fibrosis; Epithelium; Gluconates; Humans; In Vitro Techniques; Male; Sweat Glands | 1986 |
Increased nasal potential difference and amiloride sensitivity in neonates with cystic fibrosis.
Topics: Adult; Amiloride; Biological Transport; Child; Chlorides; Cystic Fibrosis; Electron Transport; Humans; Infant, Newborn; Nasal Mucosa; Potentiometry; Sodium; Sweat | 1986 |