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amifostine anhydrous and Thyroid Neoplasms

amifostine anhydrous has been researched along with Thyroid Neoplasms in 12 studies

Amifostine: A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
amifostine : An organic thiophosphate that is the S-phospho derivative of 2-[(3-aminopropyl)amino]ethanethiol. A prodrug for the free thiol, WR-1065, which is used as a cytoprotectant in cancer chemotherapy and radiotherapy.

Thyroid Neoplasms: Tumors or cancer of the THYROID GLAND.

Research Excerpts

ExcerptRelevanceReference
"Since differentiated thyroid cancer has a good prognosis, reduction of long-term side effects is important."2.69Salivary gland protection by amifostine in high-dose radioiodine treatment: results of a double-blind placebo-controlled study. ( Bohuslavizki, KH; Brenner, W; Clausen, M; Henze, E; Klutmann, S; Mester, J, 1998)
"Xerostomia was graded according to WHO criteria."2.69Salivary gland protection by amifostine in high-dose radioiodine therapy of differentiated thyroid cancer. ( Bleckmann, C; Bohuslavizki, KH; Brenner, W; Clausen, M; Henze, E; Klutmann, S; Lassmann, S; Mester, J, 1999)
"Xerostomia was graded according to WHO-criteria."2.69Radioprotection of salivary glands by amifostine in high-dose radioiodine treatment. Results of a double-blinded, placebo-controlled study in patients with differentiated thyroid cancer. ( Bleckmann, C; Bohuslavizki, KH; Brenner, W; Buchert, R; Clausen, M; Henze, E; Klutmann, S; Kröger, S; Mester, J, 1999)
"Since differentiated thyroid cancer has an excellent prognosis, reduction of long-term side effects of high-dose radioiodine treatment (HD-RIT), i."2.69Salivary gland protection by S-2-(3-aminopropylamino)-ethylphosphorothioic acid (amifostine) in high-dose radioiodine treatment: results obtained in a rabbit animal model and in a double-blind multi-arm trial. ( Bohuslavizki, KH; Buchert, R; Clausen, M; Jenicke, L; Klutmann, S; Kröger, S; Mester, J, 1999)
"Standard treatment of differentiated thyroid cancer includes total thyroidectomy and high-dose Radioactive Iodine Therapy (RIT) for ablation of remnant thyroid tissue."1.51Radioprotective Effects of Amifostine, L-Carnitine and Vitamin E in Preventing Early Salivary Gland Injury due to Radioactive Iodine Treatment. ( Altun, GD; Ergulen, A; Muratli, A; Serim, BD; Torun, N, 2019)
"Patients with well-differentiated thyroid cancer have a good prognosis but a significant chance for local recurrence."1.32Quality of life with well-differentiated thyroid cancer: treatment toxicities and their reduction. ( Elkins, D; Goffman, TE; Karakla, D; Mason, ME; Mendoza, A; Shaffer, B, 2004)
"Because differentiated thyroid cancer has a good prognosis, reduction of long-term side effects is important."1.30Radioprotection of salivary glands by amifostine in high-dose radioiodine therapy. ( Bohuslavizki, KH; Brenner, W; Clausen, M; Feyerabend, B; Henze, E; Hübner, RH; Klutmann, S; Lassmann, S; Lüttges, J; Tinnemeyer, S, 1998)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (41.67)18.2507
2000's4 (33.33)29.6817
2010's2 (16.67)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Auttara-Atthakorn, A1
Sungmala, J1
Anothaisintawee, T1
Reutrakul, S1
Sriphrapradang, C1
Torun, N1
Muratli, A1
Serim, BD1
Ergulen, A1
Altun, GD1
Ma, C2
Xie, J2
Chen, Q1
Wang, G2
Zuo, S2
Jiang, Z1
Mandel, SJ1
Mandel, L1
Mendoza, A1
Shaffer, B1
Karakla, D1
Mason, ME1
Elkins, D1
Goffman, TE1
Kim, SJ1
Choi, HY1
Kim, IJ1
Kim, YK1
Jun, S1
Nam, HY1
Kim, JS1
Bohuslavizki, KH5
Brenner, W4
Klutmann, S5
Hübner, RH1
Lassmann, S2
Feyerabend, B1
Lüttges, J1
Tinnemeyer, S1
Clausen, M5
Henze, E4
Mester, J4
Bleckmann, C2
Kröger, S2
Buchert, R2
Jenicke, L1

Reviews

4 reviews available for amifostine anhydrous and Thyroid Neoplasms

ArticleYear
Prevention of salivary gland dysfunction in patients treated with radioiodine for differentiated thyroid cancer: A systematic review of randomized controlled trials.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Adenocarcinoma; Amifostine; Bethanechol; Humans; Iodine Radioisotopes; Pilocarpine; Randomized Contr

2022
Amifostine for salivary glands in high-dose radioactive iodine treated differentiated thyroid cancer.
    The Cochrane database of systematic reviews, 2009, Oct-07, Issue:4

    Topics: Adenocarcinoma, Follicular; Amifostine; Carcinoma, Papillary; Humans; Iodine Radioisotopes; Radiatio

2009
Does amifostine have radioprotective effects on salivary glands in high-dose radioactive iodine-treated differentiated thyroid cancer.
    European journal of nuclear medicine and molecular imaging, 2010, Volume: 37, Issue:9

    Topics: Amifostine; Animals; Humans; Iodine Radioisotopes; Radiation Dosage; Radiation-Protective Agents; Sa

2010
Radioactive iodine and the salivary glands.
    Thyroid : official journal of the American Thyroid Association, 2003, Volume: 13, Issue:3

    Topics: Amifostine; Carcinoma, Papillary; Humans; Iodine Radioisotopes; Radiation Injuries; Radiation-Protec

2003

Trials

5 trials available for amifostine anhydrous and Thyroid Neoplasms

ArticleYear
Limited cytoprotective effects of amifostine in high-dose radioactive iodine 131-treated well-differentiated thyroid cancer patients: analysis of quantitative salivary scan.
    Thyroid : official journal of the American Thyroid Association, 2008, Volume: 18, Issue:3

    Topics: Adult; Aged; Amifostine; Cell Differentiation; Combined Modality Therapy; Cytoprotection; Female; Hu

2008
Salivary gland protection by amifostine in high-dose radioiodine treatment: results of a double-blind placebo-controlled study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1998, Volume: 16, Issue:11

    Topics: Adenocarcinoma, Follicular; Adult; Amifostine; Carcinoma, Papillary; Double-Blind Method; Female; Hu

1998
Salivary gland protection by amifostine in high-dose radioiodine therapy of differentiated thyroid cancer.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1999, Volume: 175, Issue:2

    Topics: Adult; Aged; Amifostine; Carcinoma, Papillary; Drug Evaluation; Female; Humans; Iodine Radioisotopes

1999
Radioprotection of salivary glands by amifostine in high-dose radioiodine treatment. Results of a double-blinded, placebo-controlled study in patients with differentiated thyroid cancer.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1999, Volume: 175 Suppl 4

    Topics: Adenocarcinoma, Follicular; Adult; Aged; Aged, 80 and over; Amifostine; Carcinoma, Papillary; Double

1999
Salivary gland protection by S-2-(3-aminopropylamino)-ethylphosphorothioic acid (amifostine) in high-dose radioiodine treatment: results obtained in a rabbit animal model and in a double-blind multi-arm trial.
    Cancer biotherapy & radiopharmaceuticals, 1999, Volume: 14, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Amifostine; Animals; Antiemetics; Blood Pressure; Dose-Response Rela

1999

Other Studies

3 other studies available for amifostine anhydrous and Thyroid Neoplasms

ArticleYear
Radioprotective Effects of Amifostine, L-Carnitine and Vitamin E in Preventing Early Salivary Gland Injury due to Radioactive Iodine Treatment.
    Current medical imaging reviews, 2019, Volume: 15, Issue:4

    Topics: Amifostine; Animals; Carcinoma, Papillary; Carnitine; Guinea Pigs; Injections, Intramuscular; Iodine

2019
Quality of life with well-differentiated thyroid cancer: treatment toxicities and their reduction.
    Thyroid : official journal of the American Thyroid Association, 2004, Volume: 14, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Amifostine; Chronic Disease; Fatigue; Fem

2004
Radioprotection of salivary glands by amifostine in high-dose radioiodine therapy.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1998, Volume: 39, Issue:7

    Topics: Adenocarcinoma, Follicular; Adult; Aged; Amifostine; Animals; Carcinoma, Papillary; Case-Control Stu

1998