amifostine anhydrous has been researched along with Sarcoma in 6 studies
Amifostine: A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
amifostine : An organic thiophosphate that is the S-phospho derivative of 2-[(3-aminopropyl)amino]ethanethiol. A prodrug for the free thiol, WR-1065, which is used as a cytoprotectant in cancer chemotherapy and radiotherapy.
Sarcoma: A connective tissue neoplasm formed by proliferation of mesodermal cells; it is usually highly malignant.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Seventy-three dogs with soft tissue sarcomas were randomized to 2 dose response assays to receive irradiation alone or with the radioprotector WR-2721." | 2.66 | Influence of WR 2721 on radiation response of canine soft tissue sarcomas. ( Dewhirst, MW; Gillette, EL; McChesney, SL; Withrow, SJ, 1986) |
| "Metformin (250 mg/kg) was effective in protecting splenic cells from a 7 Gy dose in vivo (protection factor = 1." | 1.40 | Metformin exhibits radiation countermeasures efficacy when used alone or in combination with sulfhydryl containing drugs. ( Grdina, DJ; Miller, RC; Murley, JS, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Miller, RC | 1 |
| Murley, JS | 1 |
| Grdina, DJ | 1 |
| Pasetto, LM | 1 |
| Basso, U | 1 |
| Brandes, AA | 1 |
| Koukourakis, MI | 1 |
| Ozkaynak, MF | 1 |
| Sahdev, I | 1 |
| Gross, TG | 1 |
| Levine, JE | 1 |
| Cheerva, AC | 1 |
| Richards, MK | 1 |
| Rozans, MK | 1 |
| Shaw, PJ | 1 |
| Kadota, RP | 1 |
| Begg, AC | 1 |
| Terry, NH | 1 |
| McChesney, SL | 1 |
| Gillette, EL | 1 |
| Dewhirst, MW | 1 |
| Withrow, SJ | 1 |
1 review available for amifostine anhydrous and Sarcoma
| Article | Year |
|---|---|
Amifostine: is there evidence of tumor protection?
Topics: Amifostine; Animals; Antineoplastic Agents; Clinical Trials as Topic; Combined Modality Therapy; Dog | 2003 |
2 trials available for amifostine anhydrous and Sarcoma
| Article | Year |
|---|---|
A pilot study of addition of amifostine to melphalan, carboplatin, etoposide, and cyclophosphamide with autologous hematopoietic stem cell transplantation in pediatric solid tumors-A pediatric blood and marrow transplant consortium study.
Topics: Adolescent; Adult; Amifostine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplan | 2008 |
Influence of WR 2721 on radiation response of canine soft tissue sarcomas.
Topics: Amifostine; Animals; Clinical Trials as Topic; Combined Modality Therapy; Dog Diseases; Dogs; Organo | 1986 |
3 other studies available for amifostine anhydrous and Sarcoma
| Article | Year |
|---|---|
Metformin exhibits radiation countermeasures efficacy when used alone or in combination with sulfhydryl containing drugs.
Topics: Acetylcysteine; Acute Radiation Syndrome; Amifostine; Animals; Captopril; Cell Line, Transformed; Ce | 2014 |
Improved tolerability of chemotherapy in soft tissue sarcomas: old and new strategies.
Topics: Amifostine; Antineoplastic Agents; Dose-Response Relationship, Drug; Granulocyte Colony-Stimulating | 2003 |
Stromal radiosensitivity: influence of tumour type on the Tumour Bed Effect assay.
Topics: Adenocarcinoma; Amifostine; Animals; Dose-Response Relationship, Radiation; Mice; Mice, Inbred CBA; | 1985 |